Basic Information

Insect: Venustoraphidia nigricollis
Gene Symbol: -
Assembly: GCA_034508555.1
Location: JAVRKA010000027.1:748867-752148[+]

Transcription Factor Domain

TF Family: HMG
Domain: HMG_box domain
PFAM: PF00505
TF Group: Other Alpha-Helix Group
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 2.6e-18 2.2e-15 57.4 0.5 1 68 220 287 220 288 0.97

2 4 1.2e-08 1.1e-05 26.3 1.9 1 65 308 371 308 373 0.95

3 4 3.8e-06 0.0032 18.4 2.0 2 68 408 472 407 473 0.82

4 4 8.9e-06 0.0077 17.2 4.9 34 68 568 602 544 603 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	2.6e-18	2.2e-15	57.4	0.5	1	68	220	287	220	288	0.97
2	4	1.2e-08	1.1e-05	26.3	1.9	1	65	308	371	308	373	0.95
3	4	3.8e-06	0.0032	18.4	2.0	2	68	408	472	407	473	0.82
4	4	8.9e-06	0.0077	17.2	4.9	34	68	568	602	544	603	0.79

Sequence Information

Coding Sequence: ATGGTTTCCAAAAGAAAGCGTGTCAATTcagaaacattaaataaaaaaaaagtaaaaatcatttgTAAGGATAGTGATGCTGAATCAAATATACAGCTGCCGTTACCAgccacaaaaaagaaaaacaaaaacaaacgtgAAATAATTCCTCATAAAAGTGCAGACTTTTCAGTTGCACAGTCCGAACAAAGTCAAAATGTGTTAagcaatactaaaaaaaaaagtggtaATCAGAGTCcacagaaaaaaaacaagagCACAGATTCCGTACGTCCTGAAGACGATATAGAATCAGACATCGTTGAACACTTGGCAAAGGAATCAAATGTTATACCAGAAAATAATGGCACAAATAGTCAAACAATAGGCGATTTGGCAGCGTGGTCTCAAAATGACCTTTCTGAACTTTTGAAACGCATCGAGGATGCTATACCTCACCGAGATACTCTACGACATCAATCGAGAGCTGATAAATTATGCTGGGATACGGTTGCTTTTGGTACTTACAGTCCAGAACAATGTAAAGAAGCTTGGGAAaccataagaaaaaaattgagaagttatagaattttaaaagaaatggtCGATGATGCTAAGCAGTGGATTATTAAGCCATGGACTAATTTTTACCGCAAAAGCAATCGTCATCCAGAAATGCCGCGTAGACCTTTAACTTCTTATatgcttttttatttgaaaaataaagacAAAGTATTGCAAGAAAATCCAGGAATGGAaatgactggATTGTCTAGATGTATTGCGACCATGTACAAAAATATGCCACCTgagaaaaaggaaaaatataacaCTACAGCTGTACAATTACGTAAGGAATACGACTGTAAAATGGAGCAattttaTCAAAATCATCCAGAACTTATTCCACAAAAAGATAAACCAGAAAGTGATACAAAAAATCCTCATAAACCATTAACACCGTTTAGATATTTCTGTAAAAGTAAATTAGAAAAGTTTTCAAACGATCCAAATTTCGATAGAACTACCctaattgaaaaatgtaaagAACAGTGGAAATCAatgaatgataaaaaaaaagttttttggattGATTTAGCCTTGGAACAGGAAGAAAAATACAtggaacaaattaaaatacaagCAGTGAAATATTCAGATAGCACAGTTCAGCCAACCATAAAGAGTATTCTTACAAAGGAAGAAAAATTGATTAAAGAACGAATTGCTGGAAAACCAGAAAAACCACCAAACTCAGCGTATAGTCTGTTTTCTCGTATGATGTTAGTGAGCCATGAATTAAAATCTGTTTCACCTAAGGAGAGAATGCATGTCATCGCACAGCAATGGAAAGCATGCACCCcagaagaaaaaaatgaatataaagaAAGAGTAGCCCATATGATTGAACAATATAAATTAGAATACGCCACTTACTTAGAGTCATTATCGCAAGAAAAACGCGAAgaagaattattaaaaagtataccaaaaagaaaaaaaatcataaaaccgAAATCTTCTGAAGACATTTCCGATACTGTGAAAGAAGCTacaaatgaaaaagaaaagaatTCACCGAGTAAGAAGCAGCACGATGATCTGTTTGTGTATCCTCAAAACGAATTGCTGTATGCAGGAGAACCAGAGCAACCTCCACCaacggcttttttgttatttgcgaaaaaattaataaagaataaaaaagccATATCGCGGGCTGAATTAGATAAAATATGGCAAATGTTACCAGATACTGAAAAAagtaattatcaaaaaaaattgacggaaatgaaacagaaatatataaaaaactatgaACAGTTTTTGAAAGGACTTGATCCTGACCAATTCAGAGAATATTCAAATCTAaaggcaataaaaaaatcagtgccAAATACTTTATCTTCTTCGTCGTCATCTGAATGTGATTCAGATAGTGACTGTGACgatGCAAGTAGCTCTGAAGACTCTGATTCTTCTGATTCATCGTTAAGCTCAActgtttcaaaaattgaataa
Protein Sequence: MVSKRKRVNSETLNKKKVKIICKDSDAESNIQLPLPATKKKNKNKREIIPHKSADFSVAQSEQSQNVLSNTKKKSGNQSPQKKNKSTDSVRPEDDIESDIVEHLAKESNVIPENNGTNSQTIGDLAAWSQNDLSELLKRIEDAIPHRDTLRHQSRADKLCWDTVAFGTYSPEQCKEAWETIRKKLRSYRILKEMVDDAKQWIIKPWTNFYRKSNRHPEMPRRPLTSYMLFYLKNKDKVLQENPGMEMTGLSRCIATMYKNMPPEKKEKYNTTAVQLRKEYDCKMEQFYQNHPELIPQKDKPESDTKNPHKPLTPFRYFCKSKLEKFSNDPNFDRTTLIEKCKEQWKSMNDKKKVFWIDLALEQEEKYMEQIKIQAVKYSDSTVQPTIKSILTKEEKLIKERIAGKPEKPPNSAYSLFSRMMLVSHELKSVSPKERMHVIAQQWKACTPEEKNEYKERVAHMIEQYKLEYATYLESLSQEKREEELLKSIPKRKKIIKPKSSEDISDTVKEATNEKEKNSPSKKQHDDLFVYPQNELLYAGEPEQPPPTAFLLFAKKLIKNKKAISRAELDKIWQMLPDTEKSNYQKKLTEMKQKYIKNYEQFLKGLDPDQFREYSNLKAIKKSVPNTLSSSSSSECDSDSDCDDASSSEDSDSSDSSLSSTVSKIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01530156;
90% Identity: iTF_01530156;
80% Identity: -