Basic Information

Insect: Venusia cambrica
Gene Symbol: -
Assembly: GCA_951394065.1
Location: OX596040.1:14389771-14394316[+]

Transcription Factor Domain

TF Family: E2F
Domain: E2F_TDP domain
PFAM: PF02319
TF Group: Helix-turn-helix
Description: This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.026 1.9e+02 2.5 0.0 42 58 33 49 31 53 0.87

2 19 0.026 1.9e+02 2.5 0.0 42 58 80 96 78 100 0.87

3 19 0.026 1.9e+02 2.5 0.0 42 58 127 143 125 147 0.87

4 19 0.026 1.9e+02 2.5 0.0 42 58 174 190 172 194 0.87

5 19 0.026 1.9e+02 2.5 0.0 42 58 221 237 219 241 0.87

6 19 0.026 1.9e+02 2.5 0.0 42 58 268 284 266 288 0.87

7 19 0.026 1.9e+02 2.5 0.0 42 58 315 331 313 335 0.87

8 19 0.026 1.9e+02 2.5 0.0 42 58 362 378 360 382 0.87

9 19 0.026 1.9e+02 2.5 0.0 42 58 409 425 407 429 0.87

10 19 0.026 1.9e+02 2.5 0.0 42 58 456 472 454 476 0.87

11 19 0.026 1.9e+02 2.5 0.0 42 58 503 519 501 523 0.87

12 19 0.026 1.9e+02 2.5 0.0 42 58 550 566 548 570 0.87

13 19 0.026 1.9e+02 2.5 0.0 42 58 597 613 595 617 0.87

14 19 0.026 1.9e+02 2.5 0.0 42 58 644 660 642 664 0.87

15 19 0.026 1.9e+02 2.5 0.0 42 58 691 707 689 711 0.87

16 19 0.026 1.9e+02 2.5 0.0 42 58 738 754 736 758 0.87

17 19 0.026 1.9e+02 2.5 0.0 42 58 785 801 783 805 0.87

18 19 0.026 1.9e+02 2.5 0.0 42 58 832 848 830 852 0.87

19 19 0.028 2e+02 2.4 0.0 42 58 879 895 877 898 0.87

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.026	1.9e+02	2.5	42	58	33	49	31	53	0.87
2	19	0.026	1.9e+02	2.5	42	58	80	96	78	100	0.87
3	19	0.026	1.9e+02	2.5	42	58	127	143	125	147	0.87
4	19	0.026	1.9e+02	2.5	42	58	174	190	172	194	0.87
5	19	0.026	1.9e+02	2.5	42	58	221	237	219	241	0.87
6	19	0.026	1.9e+02	2.5	42	58	268	284	266	288	0.87
7	19	0.026	1.9e+02	2.5	42	58	315	331	313	335	0.87
8	19	0.026	1.9e+02	2.5	42	58	362	378	360	382	0.87
9	19	0.026	1.9e+02	2.5	42	58	409	425	407	429	0.87
10	19	0.026	1.9e+02	2.5	42	58	456	472	454	476	0.87
11	19	0.026	1.9e+02	2.5	42	58	503	519	501	523	0.87
12	19	0.026	1.9e+02	2.5	42	58	550	566	548	570	0.87
13	19	0.026	1.9e+02	2.5	42	58	597	613	595	617	0.87
14	19	0.026	1.9e+02	2.5	42	58	644	660	642	664	0.87
15	19	0.026	1.9e+02	2.5	42	58	691	707	689	711	0.87
16	19	0.026	1.9e+02	2.5	42	58	738	754	736	758	0.87
17	19	0.026	1.9e+02	2.5	42	58	785	801	783	805	0.87
18	19	0.026	1.9e+02	2.5	42	58	832	848	830	852	0.87
19	19	0.028	2e+02	2.4	42	58	879	895	877	898	0.87

Sequence Information

Coding Sequence: ATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGGACAGGGCGGTGgtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGCGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTagtcaagtcgtaccgacgcggtGACCAAGATGTGCTGCTTGATGTCCAAAATGTTCTGCGTGGTTACAGGTGTGTACAGCGGGATGACCGGAGTGTACAGGAAGGTGGTCAAGTCGTACCGGCGCGGTGA
Protein Sequence: MFCVVTGVYSGMTGADRAVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGVYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGVYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGAYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGVYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGVYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGVYSGMTGVYRKVVKSYRRGDQDVLLDVQNVLRGYRCVQRDDRSVQEGGQVVPAR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -