Basic Information

Transcription Factor Domain

TF Family: CBF
Domain: CBF_beta domain
PFAM: PF02312
TF Group: Beta-Scaffold Factors
Description: Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 1.4e-43 2.7e-39 135.6 0.2 1 94 33 119 33 124 0.94

2 2 7.2e-40 1.4e-35 123.5 0.2 81 163 125 209 119 213 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	1.4e-43	2.7e-39	135.6	0.2	1	94	33	119	33	124	0.94
2	2	7.2e-40	1.4e-35	123.5	0.2	81	163	125	209	119	213	0.93

Coding Sequence: ATGCACACAATGAGTGACCCGGCGGCGCTGGCTGGGATGCTGCCCTTCGACTCCATCGGCCTCTACGAGCAGCCGAAGCCTCGGTTCATCTTCAAGATGCCGCGCGTGGTTCCTGACCAAAAAGGAAAATTTGAATCCGATGATCTCTTTAAAAGACTGAGCAGGGAAAGTGAGGTCCGTTACACAGGCTACCGGGACAGGCCGCCAGAGGAGCGCCAGATGCGCTTCACCAGCGGATGCCGGGAGGGTCACACAGAGATAGCCTTCACAGCCACTGGCACCAACCTACAGCTCGTGTTCGACCACTCCCCCTACAACAACCGAGGCTGTGACTTCCAGAAGGAGAACGGCAAGCTAATTTACGATCACTCTCCTTACAAGAACCGAGGCTGTGACTTCCAGAAGGAGAACGGCAAGGTACACATCGTCTCCCGTTTCATAATGAATGGCGTGTGCGTCCGATGGCGCGGCTGGCTGGATCTGGAGCGGTTGGACGGGGCCGGGTGTCTCGAGCTGGACGAGGAGCGCGCTGCGATGGAGGACGCGGCGTTGCGCGAGCAGATCGACAGATACAACCAGCGGCTGCGCGAGTTCGAGGACAAGCAGCGCGCGTACCGCGAGCACGGCGACGAGCTGCGGCACTCGCACGCGCACGCGCAGCGCTGCCACCAGGCGCGCCAGCCGCCGCACGCCGCGCACCCGACGCACCCGCACCCGGCGCACCCTGTACACATCAAACCACACTCGCAGGGCGCGCTCATTTCCTAA
Protein Sequence: MHTMSDPAALAGMLPFDSIGLYEQPKPRFIFKMPRVVPDQKGKFESDDLFKRLSRESEVRYTGYRDRPPEERQMRFTSGCREGHTEIAFTATGTNLQLVFDHSPYNNRGCDFQKENGKLIYDHSPYKNRGCDFQKENGKVHIVSRFIMNGVCVRWRGWLDLERLDGAGCLELDEERAAMEDAALREQIDRYNQRLREFEDKQRAYREHGDELRHSHAHAQRCHQARQPPHAAHPTHPHPAHPVHIKPHSQGALIS

Sequence clustering based on sequence similarity using MMseqs2