Tatt010626.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Trypoxylon attenuatum
Gene Symbol
ttk
Assembly
GCA_963989405.1
Location
OZ022491.1:19328380-19334814[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.3e-26 3.6e-24 85.2 0.1 1 102 21 119 21 123 0.93

Sequence Information

Coding Sequence
ATGGGAAGTGAGCATTACTGCCTGAGGTGGAACAATCATCAGAGCAACTTGCTGGGTGTGTTCAGTCAACTGCTGGAGTCGGAGTCGCTGGTGGACGTGACCCTGGCGTGCACGGAGGGACCGTCGATACGCGCCCACAAGGTAGTCCTCTCCGCGTGCTCCAGCTACTTCCAGGCCCTATTCCTCGACCACCCGAACCGCCACCCCATAGTCATCCTAAAGGACGTACGTTTCGCCGAGCTACGTACCCTCGTCGACTTCATGTACAAGGGCGAGGTAAACGTCGAGTACTGCCAGTTATCGGCCCTCCTAAAGACAGCGGAGAGCCTCAAGGTGAAGGGTCTCGCGGACATGACGAATATCAACGCGGCGGTCGCTTCGAGGGACGAAccacaacagcagcaacaacaaccacagcagcaacaacagcagcagcaacagcagcaacaacataCGAGTGGATCCGAGGGTATCCAGCGTGAAACGTCGAGAGAACACCATCGTGAGCGCGATAGCATAAAGGAAGTGAGCAATAAGGAGAGAGACAGGGAAGGCAACAACGCCAGTGCCGGTGGTACGGCAGTGCCATCCTTAAGCTCGAAGGAATGCGAGCAACCCCAACAGAATGTAGCCCAACCACCCACCAGTGAATCGGCGGAGCCAGTCGACATGACGGATTGTCCACCTTCGCCAACCGGACCCGGTAGCCCTTGTCCTGGACCCCTGGCACTCGATCGACCCAGGAGAGACTCCGAAGACGCGGCCAGTCTCGAAGAAACAAGAGGATCTCTCAGTCCAATTTCTGTGCATAGCGGACCATCCGACATGAGCCTCAGCAACAATACCGGCGGCACACCTGGTGTACTACCCCTGAACCTACCGCAGAGCCGGCTTCCGTCCCCGCACAGTACAGAGCCTCTCGCGGGCCCCTCGGGGTTGCCCCCGGTGCAGCAAGTTCCGCTTTCATTGAAGAAAGAGATGGACTGGGAAAGGTCGACCGAGGAACGCAGTGCGAGCAGCGAAATATCCACGGACTACAGACTCCCACCAGATCCGGAGTTAATGGGTGTGGATGAGCGGGTGTTTGCGTGCATGTACTGCGGTGCCTCGTTCCTCCACCAGAGCAAGCTGACGCGGCACATCCTCTCGCACAGCCTCGAGTCGCTCAAGTACCGCGAGCAAGCGGCCCACCTGCAGCTGCAGGCGCAGTTGGGCCTCGAGCCCGGCATGCACCTGCCGCCCGAGGCCCACTACCCGGCCACAGGTACGATCGAGCCGATGGACCTCGAGCTCGCGGCCCACTCGGACCCGACCTCCGGCGTCGTCCTCTGCAAGTTTTGCGGCAAGTCCTTCCCGGACGTCGGCTCCCTGATAGCCCACCTACCGGCACACACGGGCGATCGGCCCTTCAAGTGCGAGTTCTGTGGCAAGGCCTTCAAGCTGCGCCATCACATGAAGGACCACTGTCGAGTGCACACCGGCGAGCGGCCTTTCCGCTGTACTCTGTGCGGCAAGACCTTCTCGAGGTCGACGATACTCAAGGCCCACGAAAAGACACACTACCCCAAGTATGTGCGCAAGTTCCTGTCCCCGAGCCCCGTGGACCCCTCCGAGGAAGAGGCcccaccgccgccaccgccgcatCATTGA
Protein Sequence
MGSEHYCLRWNNHQSNLLGVFSQLLESESLVDVTLACTEGPSIRAHKVVLSACSSYFQALFLDHPNRHPIVILKDVRFAELRTLVDFMYKGEVNVEYCQLSALLKTAESLKVKGLADMTNINAAVASRDEPQQQQQQPQQQQQQQQQQQQHTSGSEGIQRETSREHHRERDSIKEVSNKERDREGNNASAGGTAVPSLSSKECEQPQQNVAQPPTSESAEPVDMTDCPPSPTGPGSPCPGPLALDRPRRDSEDAASLEETRGSLSPISVHSGPSDMSLSNNTGGTPGVLPLNLPQSRLPSPHSTEPLAGPSGLPPVQQVPLSLKKEMDWERSTEERSASSEISTDYRLPPDPELMGVDERVFACMYCGASFLHQSKLTRHILSHSLESLKYREQAAHLQLQAQLGLEPGMHLPPEAHYPATGTIEPMDLELAAHSDPTSGVVLCKFCGKSFPDVGSLIAHLPAHTGDRPFKCEFCGKAFKLRHHMKDHCRVHTGERPFRCTLCGKTFSRSTILKAHEKTHYPKYVRKFLSPSPVDPSEEEAPPPPPPHH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01498475; iTF_00291875; iTF_00294821; iTF_00291655; iTF_00294056; iTF_00294601; iTF_00293296; iTF_00293840; iTF_00293073; iTF_00770691; iTF_01198988; iTF_00770477; iTF_01199725; iTF_01199512; iTF_01198779; iTF_01538085; iTF_01538307; iTF_00298438; iTF_00298659; iTF_00140679; iTF_00140865; iTF_00295592; iTF_00295373; iTF_00296913; iTF_00297138; iTF_00296138; iTF_00296359; iTF_00773962; iTF_00773917; iTF_00774078; iTF_00088363; iTF_00088137; iTF_00297675; iTF_00297894; iTF_00361196; iTF_00360993; iTF_01473292; iTF_01473505; iTF_01255791; iTF_01255976; iTF_00254449; iTF_00254673; iTF_00252405; iTF_00252183; iTF_00633907; iTF_00633733; iTF_01131155; iTF_01130931; iTF_01475571; iTF_01475790; iTF_00218516; iTF_00218698; iTF_01090260; iTF_01090082; iTF_01539700; iTF_01539885; iTF_00089142; iTF_00088929; iTF_00215798; iTF_00215979; iTF_00223286; iTF_00223467; iTF_00255190; iTF_00255414; iTF_00252927; iTF_00253152; iTF_01395222; iTF_01395437; iTF_01454457; iTF_01454282; iTF_00087290; iTF_00087506; iTF_00253690; iTF_00253912; iTF_00224156; iTF_00223970; iTF_00730876; iTF_00731035; iTF_01475036; iTF_01474811; iTF_00393693; iTF_00393870; iTF_00086686; iTF_00086412; iTF_00222782; iTF_00222616; iTF_00228766; iTF_00228948; iTF_00729630; iTF_00729437; iTF_01474270; iTF_01474049; iTF_00085504; iTF_00085744; iTF_00217344; iTF_00217164; iTF_00996640; iTF_00996463;
90% Identity
iTF_00223286;
80% Identity
iTF_01498475;