Tlin005632.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tromatobia lineatoria
Gene Symbol
ZFX
Assembly
GCA_949699805.1
Location
OX453036.1:14080160-14085484[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.4 1.8e+02 3.7 0.1 3 23 16 36 15 36 0.94
2 15 3.5 4.5e+02 2.4 3.8 1 23 920 943 920 943 0.81
3 15 0.0029 0.37 12.1 0.6 2 23 1027 1049 1026 1049 0.95
4 15 0.0035 0.45 11.8 0.1 2 23 1062 1083 1061 1083 0.97
5 15 2.7e-05 0.0035 18.5 1.4 2 23 1086 1107 1085 1107 0.97
6 15 0.0076 0.98 10.8 0.3 1 23 1113 1135 1113 1135 0.95
7 15 2.7e-05 0.0035 18.5 4.5 2 23 1142 1163 1141 1164 0.95
8 15 0.12 16 7.0 3.7 5 23 1177 1195 1176 1195 0.97
9 15 2.4e-05 0.0031 18.6 1.5 3 23 1202 1223 1201 1223 0.97
10 15 0.014 1.8 10.0 0.5 2 23 1239 1259 1238 1259 0.97
11 15 7.4e-05 0.0095 17.1 0.7 1 20 1265 1284 1265 1287 0.92
12 15 9.2e-05 0.012 16.8 2.7 1 23 1295 1317 1295 1317 0.99
13 15 0.0026 0.33 12.3 3.2 1 23 1323 1345 1323 1345 0.97
14 15 4.7e-06 0.0006 20.9 3.9 1 23 1351 1373 1351 1373 0.99
15 15 0.00033 0.043 15.1 7.2 1 23 1379 1401 1379 1402 0.96

Sequence Information

Coding Sequence
ATGGATCTCGGCGGCGTTGCGTCAACTGGCGCTGGTTCGGTCGCCTGTCCCGTTTGTACCCTCTACTTGCGAGAGGGCATCAGCCTCCAGCGGCATTTGGACACTCATCCCAAAGAACAGGTTATAGAGGCACTAATTAAAGCAAGTTCAACGCCAACCCCGTCCCCAGCCCCAACCCCAACTCCACCGATTCCACCTACGATACCGCCTGCCCCAAACACACCGCAGAATCCCCAACATCAGGTTAATCCGGGCGCTCAGATACCTGCTCAATCGCCCTATCCTATGGGACCTGTTTTTGAGTGTCCGCCTATAAATACAATGATGCCGCCTCAATTTGCCTCGTTCAGTTATCAGCAATTTGTCAACAATGGCACGATGATGATACCGCAGTATGCAATGGCTCCTCAGGCCAATCAGATGATGCAGATGCTTTACAATCCTTACGGAATGTATCAGCAGCAACAGATACCCACCGTCCAAATGATCTCGCCCATCACAGCTATTCCTACCACTAGAATCAGACCCGTTGTTACTGTGGCTAGCGACGTTAATCCCAGGAGTGTTATTATACCCAATGGAGCAACGGAGCCCAAGCAGATATCCAACGAATTGCTTGCCGAGTCTGAGGCTGAAAGAATCCTGCCTGATATCGAACTTCCTAACACTCCTGTTCCTTCGGAGGATGAGATATTGCCTTCTAGGCATGAATCCGAAGAAGGAGGCGAACATCAGGAACACAGGGAACAGCAGATGCAAAATAACCTTATTCAGAGGATGGATAACGAGCGTCAGGACTATCAGAACTCTCAGCATTCCGATGGTGATAATTGCAAAACTGGCAACAGCGAAGAGGACGAAGCCGAGAGTATATTGCCTGATGTTGTTGAGAGGGACTCACATATAAACACACAAGTACAATGTAAAACTATAGAGTTTGAGGAACAGGAGAGCAGAGAATTTCCACAGGGTTATGAGAATCAGATGGAAAAAAGCAGGGCTAATGAGAGGGAAATTGAGAGGGATGATGCTGAAGCGATTAAACTTGAAGGGGAACATATTATGGAGAATCGCGAGTGCCCGGGAGAGAGTATGGGTTCGCAGCAGCAACGCGAGCAGGAAAAAATGAAGAGTGGCGAACCGGAAGTCGAGGAACTCGAGCATCTGCTCATAAACGTTATGGAAACGGGATTCGAAAGCGGACGCACTAAGAACTTGAAGGAAGACGCGAAAAAAGTGGAAGAGGAGCAGGAGAGTTCGCCCCTTGAAAATTCAGCGAATATGGACGCAGAAGCTCAAGAGAAGAACGAAGAAACGAGGAAAATGTACACCGAAGAATTGCAGGACGAATCGCCCTGCAAAAGTATGAATGACAACGTCGAGAGCATCGAGGAAATCGACTCCAGTGTTAATCATACTTATCGGTACAGATGTAGCTTGTCCGCTCCTTCCTCGCCCGCTGCGCCCAAAAAACTCTACAGAACTTACTCAATGAGATCCGAATACGGATCCAACGAGAATCTCAATTTTTATCCCGCTGGATTCGACGCTGCGGCTCTTCAAGATGCTGAAGACGAGGAGATGAAGAACATGGAGGATAATCTGGACGAGGAGGATATGGAGATCGAGGAAATCGCCAGTCCGCACACGCCTTTTGTTAAACAAAACAATTCTCGTGATCGCGTGAGATCTCACAGTCCTGCATCCGCGATAAGTGGCATTTCCGGTCTCCGGGTACAGAGCGCACGAAGCAAAGCCTGCTCGCCTGCTTCCGATCACGCATTTCAACCGATGGACACcgaagaagaggaagacgaCGTAAGACATCAACGGCAACTACGACAACAGCATAAACaagacgaggaggaggaggacgaagaagaggacgaagaggaacaagaggaagaagaagacgaggacgacgaggacggcgaagaagacgaagagagcAACGATTCCGTTGATTTGTCGATGAAGAAACATCCCGTCGATTGCTCGCGAAACGAACAAGAGTCTAAGCCAAACGTGCTAGAAACAAGTCCCGCGGAAAGTCTGGAGAGGAAGTTCGATTCTAATCAGATTTATCATCAATCGGTTATCACCGAACATGTTAGCTCGTTTCCAACGATAAACTCGCAACAACCTTTGATAATACACGAGAGTTATTCGGTTTCGAGCAACAAATCTACGCATAATAATCTACTGAATCTCTCGGAACTCGTTGATCCTACGACCAGCGCTGAATCCAGGAGCTTTCAGGCCGCTAAGACCATTCATCATTTACCATCGACGGAGCTTCTCAATATTAACGAAGACGCTCATGCCGGACCGATGAATGTCTTTGAATTCGACGGACTTCAAATTTTAGTTCCTAGTACATTCATAAGCGAATCTTCTCAGAAAGCCATCAGCGCTACCAGCCAACAATCGATGGCCAGCAGCGAAGGAGGCGCCGGAATCGACGAGGAGGTCAAGAGCGTCAATATGCGGGCCGATGAGACGATGCCACCGCGCGGTGAACTCTCCGAACAAGAGAGCAACGGATGCACTGAACCGTCCGCCTGGCAGCTTTACATGGGCCAAGAATCGTCGCGCATGTCGACGTCCTACGACCTCATGGCTCGCGAGAGTTGGGAAGAGTCGGAGGGTTCCGACAACGAGGTGGGAGTGCCACTGTTGGACAGCAGATCACTAGCAACGCACTTCACATCGAGTCTCTTCCTGGATCGAGATCGAAAGACGCCAACGAAGAGGACCTTCAAGTGTTCCCACTGCTCAGAGGTGTTCGATTGTCCTAAGGAGCGTCGTGTGCACAGCACGACAGTCCACAAGGAGGCGGGACCGAGTAGCAGCAACGATCCAACCGAGCAATCGGAAGCTAAGGACATAAAGCTCCTGGACGGTCGTATGAACGCCTTCGACGATATTTTCGTCTCGGGAATTCACGTGCAACAAACTTACCACCATCAGCAGCCGCTGCTACATCAACTGCAGCCGCCACAGCAGCCGGACGACGCAAAAGTCGATGGCGATCAGAAGATCGACGGTATCGCGAGTATTCCTCAAAATTTGGAAATATCTTGCGCAATGTGCAGCCAACGTTTCAGCAGCGAGAGATCACTTCAGGTTCACAACAGGCGAGTCCACGGCACCGAAGTGGCTCGACGACTTcaggaaatttcaaaatgtcagATCTGCAACGAGGAATTTCCCTCGGTGATGCTTTTCAACGCTCATCTCAAGATCCATCCCCTCGAGTGCGCCCAATGCGGCAAATACTTCTACAGAAAGCCCAATTTCAAGCTCCACATGAAGCGTCATCTCGGTATCAAGCCATTTCCATGCACGATATGCGACAAAGCATTCCTCACTAAGCAAAAGCTCGACGAACACACCAACGGTCACACCGGCAATGCTCCGGTTAAGTGTAATTTATGCAACGAGACTTTTCGTAGATATTCTAATTTAACCCAGCACAAGAATAGACATCATCTTAATATTAAGCGAAAACTCAAGGATTACATTTGCCACTGCGGCGAAGTTTTTCATACGAAGAAAAAGCTCGCCTGGCACAAAGAGACACATGACGAGAAACCAAAGGCTTGCACTTACTGCAACGAGAGGTTCATACACATGGCTAGCTTAACACGACACATGAGACGCGCTCACAATCGCAGATTCGTACCCGACGCTCAGCGCGAAAGCGAAAACGTCGAGTGCCCCATTTGCAAATGCATATATCTCAGATCCTCGCTTTCCGTTCATATGCGCGTTCACAACGGCGAAAGACCGTACGAGTGTCAGGTTTGCTCCAAGGCCTTCAGCACCAAATGGAATTTGCAATTGCACAAATGGACCCACGCGGCGCGCAGCACAAAACCCTTCAAGTGCAATCAGTGCAGCGCGGCGTTTTATCGACACAGCGATTATACCGCTCACATGAATTCACATCGCAACGTACGGCCCTACACGTGCAACTATTGCGGCGCTCAGTTCATTAGGAAGTACAATTGTCTTCGACACGTTAAAGAACACGAGGAAAATAAGGCGTACACGTGCGACGTTTGCAACAAGACTTTTCATCGCTCTTATTATCTCAAAGAACACTTGAGAGTTCACTCCGGCGCCAGACCCTACACTTGTCATATTTGTGGCAAATCCAGTAGCACCAAATCCAATCACAACAAACACGTTAGAATTCATCACGCACGGGAGCCTGTTAATACGGAAAATTAA
Protein Sequence
MDLGGVASTGAGSVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASSTPTPSPAPTPTPPIPPTIPPAPNTPQNPQHQVNPGAQIPAQSPYPMGPVFECPPINTMMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPITAIPTTRIRPVVTVASDVNPRSVIIPNGATEPKQISNELLAESEAERILPDIELPNTPVPSEDEILPSRHESEEGGEHQEHREQQMQNNLIQRMDNERQDYQNSQHSDGDNCKTGNSEEDEAESILPDVVERDSHINTQVQCKTIEFEEQESREFPQGYENQMEKSRANEREIERDDAEAIKLEGEHIMENRECPGESMGSQQQREQEKMKSGEPEVEELEHLLINVMETGFESGRTKNLKEDAKKVEEEQESSPLENSANMDAEAQEKNEETRKMYTEELQDESPCKSMNDNVESIEEIDSSVNHTYRYRCSLSAPSSPAAPKKLYRTYSMRSEYGSNENLNFYPAGFDAAALQDAEDEEMKNMEDNLDEEDMEIEEIASPHTPFVKQNNSRDRVRSHSPASAISGISGLRVQSARSKACSPASDHAFQPMDTEEEEDDVRHQRQLRQQHKQDEEEEDEEEDEEEQEEEEDEDDEDGEEDEESNDSVDLSMKKHPVDCSRNEQESKPNVLETSPAESLERKFDSNQIYHQSVITEHVSSFPTINSQQPLIIHESYSVSSNKSTHNNLLNLSELVDPTTSAESRSFQAAKTIHHLPSTELLNINEDAHAGPMNVFEFDGLQILVPSTFISESSQKAISATSQQSMASSEGGAGIDEEVKSVNMRADETMPPRGELSEQESNGCTEPSAWQLYMGQESSRMSTSYDLMARESWEESEGSDNEVGVPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCSEVFDCPKERRVHSTTVHKEAGPSSSNDPTEQSEAKDIKLLDGRMNAFDDIFVSGIHVQQTYHHQQPLLHQLQPPQQPDDAKVDGDQKIDGIASIPQNLEISCAMCSQRFSSERSLQVHNRRVHGTEVARRLQEISKCQICNEEFPSVMLFNAHLKIHPLECAQCGKYFYRKPNFKLHMKRHLGIKPFPCTICDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKRKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLSVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSSTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00414525;
90% Identity
iTF_00653058;
80% Identity
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