Basic Information

Insect: Ephialtes manifestator
Gene Symbol: ZFX
Assembly: GCA_963970395.1
Location: OZ019968.1:35695920-35700971[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.5 2.8e+02 3.7 0.1 3 23 16 36 15 36 0.94

2 14 0.0031 0.59 12.1 0.6 2 23 1031 1053 1030 1053 0.95

3 14 0.0038 0.72 11.8 0.1 2 23 1066 1087 1065 1087 0.97

4 14 2.9e-05 0.0055 18.5 1.4 2 23 1090 1111 1089 1111 0.97

5 14 0.0082 1.5 10.8 0.3 1 23 1117 1139 1117 1139 0.95

6 14 2.9e-05 0.0055 18.5 4.5 2 23 1146 1167 1145 1168 0.95

7 14 0.13 25 7.0 3.7 5 23 1181 1199 1180 1199 0.97

8 14 2.6e-05 0.005 18.6 1.5 3 23 1206 1227 1205 1227 0.97

9 14 0.015 2.8 10.0 0.5 2 23 1243 1263 1242 1263 0.97

10 14 7.9e-05 0.015 17.1 0.7 1 20 1269 1288 1269 1291 0.92

11 14 9.9e-05 0.019 16.8 2.7 1 23 1299 1321 1299 1321 0.99

12 14 0.0028 0.52 12.3 3.2 1 23 1327 1349 1327 1349 0.97

13 14 5e-06 0.00095 20.9 3.9 1 23 1355 1377 1355 1377 0.99

14 14 0.00036 0.068 15.1 7.2 1 23 1383 1405 1383 1406 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.5	2.8e+02	3.7	0.1	3	23	16	36	15	36	0.94
2	14	0.0031	0.59	12.1	0.6	2	23	1031	1053	1030	1053	0.95
3	14	0.0038	0.72	11.8	0.1	2	23	1066	1087	1065	1087	0.97
4	14	2.9e-05	0.0055	18.5	1.4	2	23	1090	1111	1089	1111	0.97
5	14	0.0082	1.5	10.8	0.3	1	23	1117	1139	1117	1139	0.95
6	14	2.9e-05	0.0055	18.5	4.5	2	23	1146	1167	1145	1168	0.95
7	14	0.13	25	7.0	3.7	5	23	1181	1199	1180	1199	0.97
8	14	2.6e-05	0.005	18.6	1.5	3	23	1206	1227	1205	1227	0.97
9	14	0.015	2.8	10.0	0.5	2	23	1243	1263	1242	1263	0.97
10	14	7.9e-05	0.015	17.1	0.7	1	20	1269	1288	1269	1291	0.92
11	14	9.9e-05	0.019	16.8	2.7	1	23	1299	1321	1299	1321	0.99
12	14	0.0028	0.52	12.3	3.2	1	23	1327	1349	1327	1349	0.97
13	14	5e-06	0.00095	20.9	3.9	1	23	1355	1377	1355	1377	0.99
14	14	0.00036	0.068	15.1	7.2	1	23	1383	1405	1383	1406	0.96

Sequence Information

Coding Sequence: ATGGATATCGGCGGCGTAACGGGTACTGGCGGTGGCTCGGTCGCCTGTCCCGTTTGTACCCTCTACTTGCGAGAGGGCATCAGCCTCCAGCGGCATTTGGACACTCATCCCAAAGAACAGGTTATAGAGGCACTAATTAAAGCAAGTTCAACACCAACCCCATCCCCAACCCCAACTCCAACCCCACCGATTCCGCCGACGATACCGCCCGCCCCAAATACACCGCAGACACCCCAACATCAGGTTAATCCGGGCGCTCAGATACCTGCTCAATCGCCCTATCCCATGGGACCTGTCTTTGAGTGTCCACCCATTAATACCATGATGCCGCCTCAATTTGCCTCGTTCAGTTATCAGCAATTCGTCAACAACGGCACCATGATGATACCCCAATACGCCATGGCGCCTCAGGCCAATCAAATGATGCAGATGCTTTACAATCCTTACGGAATGTATCAGCAGCAACAGATACCCACCGTCCAAATGATCTCGCCCATCACTACTATTCCTACCACTAGAATCAGACCCGTTGTTACTGTCGCAAGCGAGGTCAGTCCCAGAAGCGTTATCATACCTAACGGAGCTGCTGAGCCCAAACAGATATCTAACGAATTGCTCTCCGAGCCTGAGGCTGAAAGAATCCTACCGGATATAGAACTTTCTACTACTCCTGTTCCTTCGGAGGATGAGATTTTGCCATCGAGGCACGATTCCGATGAGACTGGCGTTCATCAGGAACACAGGGAACAGCAGATGCAAAATGGTCTCATTCAGAGGATGAACAACGAGCGTCAGGAGTATCAGAACTCTCAGCATTCCGATGGTGATAATTGCAAAACTGGCAACAGCGAGGTGGATGAAGCTGAGAGTATATTGCCCGATGTCGTGGAGAGGGACACACATATAGACACACAAGTACAATGTAAAACTATAGAGTTTGAGGAACACGAGAGCAGAGAGTTTCCACAGGGTTACGAGAGCGAGATGGAAAAGAGCGGGACTAACGAGCGTGAAATCGAGAGAGACGAGGCTGAGGCGATTAAACTTGAGAGAGAGCACACTATGGAGAATCGGGAATGCCAGGGCGAGTCTATGGCTTCGCAGCAGCAACGCGAGCAGGAAAAAATGAAGGAAACTGGCGAACCGGAAGTCGAGCAGCTCGAACATCTGCTCATTGCGGTTATGGAGTCGGGATTCGAAAATGGGCGCTCTAAGAACTCCAAGGAAGAGACGAAGAAGGCGGAAGAGGAGCAAGAGCGGTCGCCGGTCGAAGATTCAGCGAATATGGACGCAGAAACCCAAGACAAGAACGAGGAAACGAGCAAAATGTATACCGAAGAATTGCAGGACGAAACGCCCTGCAAAAGTATGAACGAGAGTGGCGAGAGCGTCGAGAGCATCGAGGAACTCGACAGCAATCCTAATCATACATATCGGTATAGATGTAGCGTGTCCGCTCCTGCCTCGCCTGCACCGAAAAAACTTTACAGAACTTACTCCATGAGGTCCGAATACGGATCCAACGAGAATCTCAATTTCTATCCCGCTGGATTCGACGCTGCGACTCTGCATGATGCTGAGGACGAGGAGATGAAGACAATGGAGGATAATCTGGACGAGGAGGACATGGAGATCGAGGAAATCGCCAGTCCGCATACGCCTTTTGTTAAACAAAACGATGCTCGCGATCGCGTTAGATCGCATAGTCCTGCGTCCGCGATAAGCGGCATTTCCGGTCTACGGGTACAGAGCGATCGAAGCAAAGCCTGCTCGCCTTCTTCCGTTCACGGTTTCCAGCCAATGGACaccgaagaagaggaagaagacgaaCGACAACAGCGGCAACAACGGCAACAGCATAAACAGGAACAGgatgaagaggaggaggaggaggaagaggaacaagaggaagaggaagaagaagacgagGATGACGAAGAGGACGAAGAGGATGAAGAAAGCAACGATTCTGTTGATTTGTCGATGAAGAAACATCCCGTTGATTCTTCGCGAAACGAGCAAAAGTCTAAGCCAAATGTGCTGGAAACAAGTCCCGCGGAAAGCCTTGAAAGAAAATTCGATTCTAATCAGATTTATCACCAATCGGTGATCACTGAACATGTTAGCTCGTTTCCTACGATAAACTCGCAACAACCTTTGATTATACACGAGAGTTATTCGGTTTCGAGCAATAAATCGACGCATAATAATCTTCTGAATCTCTCGGAACTCGTTGATCCAACGACCAGCGCCGAATCCAGGAGCTTTCAGGCCGCTAAGACAATTCATCATTTGCCCTCGACGGAGCTTCTCAATATTAATGAAGACGCTCATGCCGGGCCGATGAATGTCTTTGAATTCGACGGACTTCAAATTTTAGTTCCTAGTACATTCATAAGCGAATCTTCCCAGAAAGCCATCAGCGCTACCAGCCAACAATCGATGGCCAGCAGCGAAGGAGGCGCCGGAATCGACGAGGAGGTCAAGAGCGTCAATATGCGGGCCGATGAGACGATGCCACCGCGCGGTGAACTTTCCGAACAAGAGAGCAATGGCTGTACTGAACCTTCTGCCTGGCAGctTTACATGGGCCAAGAATCGTCACGCATGTCGACGTCTTACGACCTCATGGCTCGCGAGAGTTGGGAAGAGTCGGAGGGTTCCGACAACGAGGTAGGAGTGCCGCTGTTGGACAGCAGATCACTAGCGACGCATTTCACATCGAGTCTGTTCCTGGATCGAGACCGAAAAACGCCGACGAAGAGAACCTTCAAGTGTTCCCACTGCGTAGAGGTCTTCGATTGTCCTAAAGAGCGACGTGTGCACAGCACGACGGTACACAAGGAGGCGGGACCGAGCAGCAGTAACGATCCCACCGAACAGTCTGAAGCGAAGGACATAAAGCTCCTGGACGGTCGTATGAACGCCTTCGACGATATTTTCGTTTCCGGAATTCACGTTCAACAAACTTATCATCACCAGCAGCCACTGCTGCATCAACTGCAGCCTCCACAGCAGCCGGACGACGCGAAAGCCGACGGCGATCAGAAGATCGACGGTATCGCGAGTATTCctcaaaatttggaaatttcgtGCGCAATGTGCAGTCAACGTTTCAGCAGCGAGAGATCTCTTCAGGTTCACAACAGGCGAGTTCACGGCACCGAAGTCGCTCGACGACTTCaggaaatttcaaaatgccaGATCTGCAACGAGGAATTTCCCTCGGTGATGCTTTTCAATGCTCATCTTAAGATTCATCCCCTCGAGTGCGCCCAGTGCGGCAAATACTTCTACAGAAAGCCCAATTTCAAGCTCCACATGAAGCGTCATCTCGGTATAAAGCCATTTCCATGCACGATATGCGACAAAGCATTCCTCACTAAGCAAAAGCTCGACGAACACACCAACGGTCACACCGGCAACGCTCCGGTTAAGTGTAATTTATGCAACGAGACTTTTCGTAGATATTCTAATTTAACGCAGCACAAGAATAGACATCATCTTAATATTAAGCGCAAACTCAAGGACTACATCTGCCACTGTGGCGAAGTTTTTCATACGAAGAAAAAGCTCGCTTGGCACAAAGAAACACACGACGAGAAACCAAAGGCTTGCACTTACTGCAACGAGAGGTTCATACACATGGCTAGCTTAACGCGACACATGAGACGCGCTCACAATCGCAGATTCGTGCCTGACGCTCAGCGCGAAAGCGAAAACGTCGAGTGCCCCATTTGTAAGTGCATATATCTCAGATCCTCGCTTTCCGTTCACATGCGCGTTCACAACGGCGAACGACCTTACGAGTGCCAGGTTTGCTCCAAGGCCTTTAGCACCAAATGGAATTTGCAATTGCACAAATGGACCCACGCGGCGCGCAGCACAAAACCCTTCAAGTGCAATCAGTGCAGCGCGGCGTTTTATCGACACAGCGATTATACCGCTCACATGAATTCACATCGCAACGTACGGCCCTACACGTGCAACTATTGCGGCGCTCAGTTCATTAGGAAGTACAATTGTCTTCGACACGTTAAGGAACACGAGGAAAATAAGGCGTACACGTGCGACGTTTGCAACAAGACTTTTCATCGTTCTTACTATCTCAAAGAACACTTGAGAGTTCACTCCGGCGCGAGACCCTACACTTGTCATATTTGCGGCAAATCCAGTAGCACCAAGTCCAATCACAACAAACACGTTAGAATTCATCACGCGCGGGAGCCTGTTAATACAGAGAATTAA
Protein Sequence: MDIGGVTGTGGGSVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASSTPTPSPTPTPTPPIPPTIPPAPNTPQTPQHQVNPGAQIPAQSPYPMGPVFECPPINTMMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPITTIPTTRIRPVVTVASEVSPRSVIIPNGAAEPKQISNELLSEPEAERILPDIELSTTPVPSEDEILPSRHDSDETGVHQEHREQQMQNGLIQRMNNERQEYQNSQHSDGDNCKTGNSEVDEAESILPDVVERDTHIDTQVQCKTIEFEEHESREFPQGYESEMEKSGTNEREIERDEAEAIKLEREHTMENRECQGESMASQQQREQEKMKETGEPEVEQLEHLLIAVMESGFENGRSKNSKEETKKAEEEQERSPVEDSANMDAETQDKNEETSKMYTEELQDETPCKSMNESGESVESIEELDSNPNHTYRYRCSVSAPASPAPKKLYRTYSMRSEYGSNENLNFYPAGFDAATLHDAEDEEMKTMEDNLDEEDMEIEEIASPHTPFVKQNDARDRVRSHSPASAISGISGLRVQSDRSKACSPSSVHGFQPMDTEEEEEDERQQRQQRQQHKQEQDEEEEEEEEEQEEEEEEDEDDEEDEEDEESNDSVDLSMKKHPVDSSRNEQKSKPNVLETSPAESLERKFDSNQIYHQSVITEHVSSFPTINSQQPLIIHESYSVSSNKSTHNNLLNLSELVDPTTSAESRSFQAAKTIHHLPSTELLNINEDAHAGPMNVFEFDGLQILVPSTFISESSQKAISATSQQSMASSEGGAGIDEEVKSVNMRADETMPPRGELSEQESNGCTEPSAWQLYMGQESSRMSTSYDLMARESWEESEGSDNEVGVPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCVEVFDCPKERRVHSTTVHKEAGPSSSNDPTEQSEAKDIKLLDGRMNAFDDIFVSGIHVQQTYHHQQPLLHQLQPPQQPDDAKADGDQKIDGIASIPQNLEISCAMCSQRFSSERSLQVHNRRVHGTEVARRLQEISKCQICNEEFPSVMLFNAHLKIHPLECAQCGKYFYRKPNFKLHMKRHLGIKPFPCTICDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKRKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLSVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSSTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00414525;
90% Identity: iTF_00343361; iTF_01497675;
80% Identity: -