Basic Information

Gene Symbol
salm
Assembly
GCA_030522925.1
Location
JAPYZS010000039.1:4779-14674[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 5.1e-06 0.00056 20.8 0.9 1 23 386 408 386 408 0.98
2 8 1e-05 0.0011 19.9 2.1 1 23 414 436 414 436 0.98
3 8 0.064 7 7.9 3.8 2 23 803 824 802 824 0.98
4 8 4.4e-08 4.8e-06 27.3 0.6 1 23 830 852 830 852 0.97
5 8 2.3e-05 0.0025 18.8 2.3 1 23 862 884 862 884 0.98
6 8 0.0021 0.23 12.6 1.9 2 23 1178 1199 1177 1199 0.97
7 8 1e-06 0.00011 23.0 2.1 3 23 1379 1399 1377 1399 0.96
8 8 7.9e-07 8.7e-05 23.4 2.2 1 23 1405 1427 1405 1427 0.98

Sequence Information

Coding Sequence
ATGGAGCTTATGAGATGGAGCATCACAAAACCGCTGCAGAGCCGAGGCATCGGTGGCCGACCTATCAAACCCGCGCCTACCTCCAGGCCGCTCGACTTGCGAACTTCTCTCTCCGgagaagaaaatgattcagCCTCAGACGGGGAGGAGAGCGGAGGGGCGCCGGGCGGTGACGAGGCGGTGGATCTCACCGCGTCGCAGCGTTCACAGCCCGACGAGGAGGACGAGTTGCCCGTGGAAGACGAGGAAGAGGAGGGCATGGACGAGCCGGACGAGCACGACGACGAGGACGAGGAGGGCTCGCGCAAACGGATGCGTCACCGACAGGACGCGGAGAACAACAACAGCTTCGCGGAGGGCGCCCCCGTGCCCGGGCTGTTTCCCTCCGCCGGTACTAGTCACGTGACACTGGAGGCACTGCAGAACACGAACGTAGCCGTGGCTCAGTTCGCACCGGCGGCGCTCGCGGCGACCCCGGAGAACGAGGCTGTGCTGCAGGAGCTGGCGATACTCTACACGATCCATCAGCAGCACCAAGTATTACAACTCCAAATAATCAATCAGATCCAACAGAAGCTATCGATCAATCAGCAGGGCCAGTCGGGACAAACGACCACGACGACGTCCACGACAACGACAACGACAACGGGCGAGACGGCGCCGGTGAACGAGAGCAAGGAGCAGTCGCCCTCGCCGAGCGTGCTCTCGAAGCCGGTGTCGCTGACGTCACCGCCCCCATCCCTGTCCCGTTCGCCGATTCTGCAGCAACAGTCATCGCCGATCGCGCTGACGCCCGGCGAGCGGCCCGCGCCGTCGGCCAGCGCGTCGCCCCTGAGTGTGCCTGTGACGACCGCGGCGACGACGCCGAGCATGGCGAACAGTCAGGTCGCGCTTTCTCACCAGATGCCGCCCCTTTGTTCGATCAGTTCGTCGCTGGCGTCGTCGATTATCACGAATAACGACCCGCTGCCACTGCACGAGCCAAATACCCTGGAGGTGTTACAGAAGAGAGCTCAAGAGGTGCTGGACAATGCGAGTCAGGGCCTGCTGGCGAACAACCTGGCGGACGAGCTCGCGTTCAGGGGTGGTAAAGGCTCGCGGCTGTCTCCGTACGACTCGAAATCGGGCGGCGGCCGAGGCGAGCCGTTCTTCAAGCACCGCTGTCGCTACTGCGGCAAAGTGTTTGGCAGCGACTCGGCACTCCAGATCCACATACGGTCACACACAGGTGAGCGTCCCTTTAAGTGCAACGTCTGTGGAAGCCGATTCACCACCAAGGGGAACCTCAAGGTTCACTTTCAGAGGCACACGGCCAAGTTTCCGCACGTAAAGATGAATCCGAATCCCGTCCCCGAACACCTTGACAAATTTCATCCTCCCCTCCTTCAACAGCTCGCGGCGTCCGGTCAGCGACCTCTTCCATCGCCGCCGCCCCCGCCGCCGCCGTCACATGCCCAGTTTCATTCAACGCCCAATCGTGGTTTTATTCCCCAACAACAAcaaccaccaccaccacccaTACCATTGAATCTTGCCTTACCCGGTATGCCGCCCCTTTACCGATCTCCAGTCGTCAATCAGCGAGACGATCAAGACTTACCAGAGAACCTTAGCAAGCCTGTAGCACCGACACCAACTACTTCTCCGAACTCGCCCAATGCCCAATTAAATTCTCATAACCCCTTTCATGATAATCTTCAAGGTTCGCAGCCGCCACTGCAGCAACCGAAAACGAAGGATGATATCAAAGTTGAACGGCGCTCGCCGGtcgatgaacaatttcaacCGAGGCCGATCAGCCAAGAGAATAACGAGCGAATAACGCCCAAGCGCGAACCCGAGGACGCGGAGGACCCCACCGAGGACGAGAGCAAAGAGTACGACGATACGGCCCGAAGATACTCGTCGCCTCTCTCGGTGAATCCCTCGTGTCAGCCGCAGACCTACGAGGACTGCAGCATGGATAGCAAGATGAGCGGCAGACTCGAGGGCGACGTCGACATGGACGGCGAGGTCGAGATGGACGAGCAACCCGAAAATCTATCCAGCAGACCCTCGTCCAACCGTCTTCCAACGCAACTGCTCGGCTACCCTGGAGCCTCCCCGGCGAGCAGCACCGCGAGCAGTAGCAGCTTGCACACCTCCTTCGCGGGCATTCTGTACCCAGGTCCCCCGTCTCATCACCAGTTACCTCATCACCCCTCCTCCACGTCTGTGTCCACGTCTACAGGCATCAACGAGATGATCGATCCCGCGAAAGATCCCGCCATCTACTCGAGCCTCCTGCCAAGGCCCGGCAGCACCGACAACTCCTGGGAGAGTCTCATCGAGATCACAAAGACCTCGGAGACGTCCAAGTTGCAGCAGCTTGTAGATAACATTGAACATAAGCTAACCGATCCGAATCAGTGTGTGATATGCCACAGAGTTCTATCGTGCAAGAGCGCGCTGCAGATGCACTACCGAACGCACACGGGCGAGCGCCcgttcaaatgtaaaatttgcgGCCGAGCTTTCACGACGAAGGGCAACCTGAAGACGCACATGGGTGTGCACAGGGCGAAGCCACCGCTTCGGGTGCTACATCAGTGCCCGGTCTGCCATAAGAAGTTCACGAACGCGATCGTCCTGCAGCAGCACATACGACTGCACACGGGCGAACCCACTGATCTCAGCCCCGAACAAATCCAAGCCGCCGAAGTGAACGAGTTCCCGCCGGGCTATCCTCACCATCTTGCGCCCTTCCTACCCCAGGGATTCCCTCCCATGCACCCAGCAGGGACGGCGGGCTTCTCCCTAAACTTTCAACCCCGACCGCCGACAATTGGAAGGCCTCCGCCCCAAGACCACGAGATGGACACCCAAGACTCCCAACCGGCGCAATCCAACGACCAACAGTCCTACATGGATGAGCATTGCGAGGACCAAGAGGAAGACCAAGAGGACGAGGAGAAGGACAGCAGAGAAGAGGACGAGAGGTGCGAGACGGCCAACGACAGGCGAAGCATCCTCGACGAGGACGAGGAGAAGGAGCAGGAAGAGGAGATTGAGTGCAAAGACATCCCTGTCCCGTCCTTCTCGACCTCCTTGGCTGCGCTTGAAAACCAGGTCAGAACCATCACGACCATGGCGACGAGTCTGGCCAGCATAGAAAGGTCCCCGCCGCTGCACAGATTCAACGGCAGGGAAAAGAGCAACAGCCCTCCGAGCAACGGCACGCCCCTGGACCTCACGCCACGAGCCTCTTCGACGCCGGCCTCTGCGGCCTCGACGCCGACGCCACCGCCTTCAAGTGCGCCGACCACCCATCACCCGCACCCGTTCGGCATGTTCGCCGGTCTCCTGCAGGCCGCGTCGTCGTCCCCGTCATCCAACAACCTCAATAGCGTCGGTTCGATAAATGCAGTGAGTCCTGCCGGCAGTGCTGCTGGACCTCTCGCCTCTCTAACGACATCGGCGGTGCTCGCAGCCACATCAACCTATAACCCACTCGGTCTGGCTGTTGGAGGGCCAGCAGCACGTGGCAACACTACTTGCAATATCTGCTACAAGACGTTCGCATGCAATTCAGCGTTAGAGATTCATTACCGTAGTCATACAAAGGAACGACCTTTCAAaaacaaaaaagatggtGAAACCGACTCTGCAAATACAACCCAAACGAGCGCAGCGGAGAAGCCCAAGCGCAGGCGACGGCGGCCTGAGGATGCTAAAAGTCGGGGGCGGACAAGGCCCGATGGCGAGCGGGCACTGACGTCTGCTCACGCAGCCGTCTTTGGGGAAACTCGCCTGCCCCCGCTGATGCCATCCGCCCTCGGTCTTCTAGCCTCGGACCCCGTTTTCCTGGGGAATATGAAGCAGCACATGTTGACGCATAAGATACGAGACATGCCAGCCCATCTGTTCAGCGAGCCGAAACAGCCGAGTCCGAGTTCTCAGACGGTGCAGCAGGACAGGGAGTCGTCGTCGAGTCCCCTTCGCAACGACGAACCCAACAGTCTTCCGCCTCCGCCTCCACCGCCACCCCCACCTCCCCCACCGATGCCGCCTGTAGAGTCTACGGTGAAGCGAACGACCCCCGAGGGCGAGCTGCCTGCGCCAAAAAGACCATGCAGCATGTCCAGCAAGCACTTGTGCCAGGTTTGCAATAAGAATTTCTCCTCGTCCTCGGCGCTGCAGATCCACATGAGAACGCACACTGGCGACAAACCCTTCAAGTGCGACATCTGCCATAAGGCCTTCACGACAAAGGGCAATCTCAAGGTACACACGGGAACACATATGTGGACAAACGGAACATCGCGACGAGGTCGACGAATGTCGTTGGACCTGCCGCCTCTGCCCATCACCCCCAAGGACTCGGAATTTCTGCAACGACGACCGGACCTCTTCTATCCATATCTTCACCCGCCATTCCTTAATGGTGTTCAGCCAAAACTTAACGAGATCTCGGTGATACAAAACAGCAATGGTTTGCCGGCACACTCGACGGGCGTGAGCAAATACGCCGGACTGTTTAGCTCGGTGTACGGAAGCGCGGGGTTCTCGCTGGACAAACAGCCGATGTCGCCCGGAAATGGGCCCTTGGGCGAGACCAAATCAGCGTTCCCACCCGGATCGATGCTGTTCCAGTCGCCGTCGCCGGCCCACTCGTCCGGCACCGCTTCGTCCAACGTCAACAGTCAGAACTCGCCCAGCCTACCTGCGTGGAGCTCCGAGTCGCTGCAGCACCACCACTTCGAGAGGGATGCACCGCCGCGACCCGAGAGCGACCCTACGCCACCCTCGGCACACCTCGCGCCACCACCCACGCCCCGAGGCGAGGGCCTGGCTGCGTGA
Protein Sequence
MELMRWSITKPLQSRGIGGRPIKPAPTSRPLDLRTSLSGEENDSASDGEESGGAPGGDEAVDLTASQRSQPDEEDELPVEDEEEEGMDEPDEHDDEDEEGSRKRMRHRQDAENNNSFAEGAPVPGLFPSAGTSHVTLEALQNTNVAVAQFAPAALAATPENEAVLQELAILYTIHQQHQVLQLQIINQIQQKLSINQQGQSGQTTTTTSTTTTTTTGETAPVNESKEQSPSPSVLSKPVSLTSPPPSLSRSPILQQQSSPIALTPGERPAPSASASPLSVPVTTAATTPSMANSQVALSHQMPPLCSISSSLASSIITNNDPLPLHEPNTLEVLQKRAQEVLDNASQGLLANNLADELAFRGGKGSRLSPYDSKSGGGRGEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHTAKFPHVKMNPNPVPEHLDKFHPPLLQQLAASGQRPLPSPPPPPPPSHAQFHSTPNRGFIPQQQQPPPPPIPLNLALPGMPPLYRSPVVNQRDDQDLPENLSKPVAPTPTTSPNSPNAQLNSHNPFHDNLQGSQPPLQQPKTKDDIKVERRSPVDEQFQPRPISQENNERITPKREPEDAEDPTEDESKEYDDTARRYSSPLSVNPSCQPQTYEDCSMDSKMSGRLEGDVDMDGEVEMDEQPENLSSRPSSNRLPTQLLGYPGASPASSTASSSSLHTSFAGILYPGPPSHHQLPHHPSSTSVSTSTGINEMIDPAKDPAIYSSLLPRPGSTDNSWESLIEITKTSETSKLQQLVDNIEHKLTDPNQCVICHRVLSCKSALQMHYRTHTGERPFKCKICGRAFTTKGNLKTHMGVHRAKPPLRVLHQCPVCHKKFTNAIVLQQHIRLHTGEPTDLSPEQIQAAEVNEFPPGYPHHLAPFLPQGFPPMHPAGTAGFSLNFQPRPPTIGRPPPQDHEMDTQDSQPAQSNDQQSYMDEHCEDQEEDQEDEEKDSREEDERCETANDRRSILDEDEEKEQEEEIECKDIPVPSFSTSLAALENQVRTITTMATSLASIERSPPLHRFNGREKSNSPPSNGTPLDLTPRASSTPASAASTPTPPPSSAPTTHHPHPFGMFAGLLQAASSSPSSNNLNSVGSINAVSPAGSAAGPLASLTTSAVLAATSTYNPLGLAVGGPAARGNTTCNICYKTFACNSALEIHYRSHTKERPFKNKKDGETDSANTTQTSAAEKPKRRRRRPEDAKSRGRTRPDGERALTSAHAAVFGETRLPPLMPSALGLLASDPVFLGNMKQHMLTHKIRDMPAHLFSEPKQPSPSSQTVQQDRESSSSPLRNDEPNSLPPPPPPPPPPPPPMPPVESTVKRTTPEGELPAPKRPCSMSSKHLCQVCNKNFSSSSALQIHMRTHTGDKPFKCDICHKAFTTKGNLKVHTGTHMWTNGTSRRGRRMSLDLPPLPITPKDSEFLQRRPDLFYPYLHPPFLNGVQPKLNEISVIQNSNGLPAHSTGVSKYAGLFSSVYGSAGFSLDKQPMSPGNGPLGETKSAFPPGSMLFQSPSPAHSSGTASSNVNSQNSPSLPAWSSESLQHHHFERDAPPRPESDPTPPSAHLAPPPTPRGEGLAA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01493065;
90% Identity
iTF_01493065;
80% Identity
-