Basic Information

Gene Symbol
-
Assembly
GCA_030522925.1
Location
JAPYZS010000019.1:415526-416937[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 6.7e-05 0.021 15.6 2.5 2 108 28 154 27 156 0.73
2 3 4.7e-17 1.5e-14 54.7 0.7 2 109 237 337 234 338 0.89
3 3 3.1 9.8e+02 0.6 0.1 81 101 341 361 336 368 0.83

Sequence Information

Coding Sequence
atggaaGAGAATGATTATGAAGAAAACAAAAATTTGGAACCAGAAGATTCGAAATTCTTTCGGAACTTTCAGAGCGACATGAAAGAAATGTTCAACAATTCGGTGTGTTCCGATATCAAAATACTTATCGATTACAAGGTCATCAGAGGTCATAAACTCATTCTTCTGGGAAATCCatcattttctaaaatgaTAGCCTCGAATCCAGACTTGAAAGAAATCTACTTCTCCGATCAGATATCCGATTCGGTTGAACGCGATATCCGACATCTGTTTTGCGATAACTTTGACCAGGAGAAGGAGgacgttttacaattttcatcagaagcttgtgaaacatttttgcgaTATCTCTATGGAATGGaagtcaaaaaagaaatgatcaaTCTTGATTTGATGTTGGTCGCCTATAAGTTCTCTGATGAGATGCTCAaagatttttgtcaaaaacatCTGATCAAAGATGTAAATGTGAGAAATGCAGTTCGAACACTTTTGGTTTCATTAGAAACTCAATCTGAAAAACTTAAAATCGAGGCATGCAAGTTGATAGCGAGGAATTTCAATGAGATGAAATTCAACCAGGATTTAAATCTTATCCTGGAAAATGAAGCTGCCCTTTCTGAGATTCTAAATGTTTTTGatgactGCGAAACAATTCTCCTTAAGTCAAAAATGAAGGATGAGAATCTTGAATATGACTCACTGAACCAATTGCGCAGTACAGATTTAATGATGACAGTTGGGAACCACCACTTCCTGGCCCACAAGAAGATACTTTCTGAACGAAATGCAGTGTTCAAGGTGATCATCGATGCTGCTTCCTCGGATGGTTTCCCTACATCCGTCAACATCCCAGATGTCGACCATAAaagtttcaagatttttttgcattttatttacacCGACGAAGTAAATCGTTACTATGTTTCtgacaatttattgaaattagcTCACATGTACACTGatgataaattgaaagaaatctGTGAGATAgagtttattcaaaaacttgaTTACGATAATGCTATTAAGTTGTTGTTCGTTgctatgaaatttgaatgcaaGCATCTTCAGAAGTGTGCTTTAAACTATATTCTTGTTAGATATGAAGAAATTTCATCTCAAGATGATTACCAGAAGCTTGTACAAAATCTTGACGctacaaatttgttaattagaACTTTACGTAAGAGGCTAAAACCAGACATAGGTATGACATGA
Protein Sequence
MEENDYEENKNLEPEDSKFFRNFQSDMKEMFNNSVCSDIKILIDYKVIRGHKLILLGNPSFSKMIASNPDLKEIYFSDQISDSVERDIRHLFCDNFDQEKEDVLQFSSEACETFLRYLYGMEVKKEMINLDLMLVAYKFSDEMLKDFCQKHLIKDVNVRNAVRTLLVSLETQSEKLKIEACKLIARNFNEMKFNQDLNLILENEAALSEILNVFDDCETILLKSKMKDENLEYDSLNQLRSTDLMMTVGNHHFLAHKKILSERNAVFKVIIDAASSDGFPTSVNIPDVDHKSFKIFLHFIYTDEVNRYYVSDNLLKLAHMYTDDKLKEICEIEFIQKLDYDNAIKLLFVAMKFECKHLQKCALNYILVRYEEISSQDDYQKLVQNLDATNLLIRTLRKRLKPDIGMT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-