Tvar017212.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Trilocha varians
Gene Symbol
-
Assembly
GCA_030269945.2
Location
AP028276.1:9780655-9787229[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 3.3 2.7e+02 3.0 0.9 1 23 54 77 54 77 0.94
2 22 0.098 8.2 7.8 2.1 1 23 84 107 84 107 0.97
3 22 2.1 1.7e+02 3.6 5.3 1 23 193 215 193 215 0.97
4 22 0.005 0.42 11.8 0.4 2 23 221 242 220 242 0.97
5 22 0.67 56 5.1 1.7 1 23 248 270 248 271 0.95
6 22 0.25 21 6.5 3.5 2 21 504 523 503 524 0.95
7 22 9 7.5e+02 1.6 1.4 1 23 621 643 621 643 0.79
8 22 7.1 6e+02 1.9 0.2 1 21 649 669 649 670 0.83
9 22 0.14 12 7.3 0.6 2 23 776 797 775 797 0.96
10 22 3.5 2.9e+02 2.9 0.9 3 23 879 899 877 899 0.95
11 22 0.23 19 6.6 2.1 1 23 907 929 907 929 0.98
12 22 0.14 11 7.3 3.3 1 23 965 987 965 987 0.95
13 22 0.00025 0.021 15.9 4.0 1 23 995 1017 995 1017 0.99
14 22 0.0025 0.21 12.8 1.5 1 23 1101 1123 1101 1123 0.98
15 22 2.6 2.1e+02 3.3 1.7 1 19 1177 1195 1177 1199 0.90
16 22 0.55 46 5.4 0.1 2 23 1206 1227 1205 1227 0.93
17 22 0.024 2 9.7 0.3 1 23 1294 1316 1294 1316 0.95
18 22 0.031 2.6 9.3 0.2 1 23 1322 1344 1322 1344 0.95
19 22 0.007 0.58 11.4 2.6 1 23 1434 1456 1434 1456 0.97
20 22 0.00017 0.015 16.4 1.4 1 23 1462 1484 1462 1484 0.99
21 22 2.6 2.2e+02 3.3 4.2 1 23 1573 1595 1573 1595 0.96
22 22 0.51 42 5.5 4.3 1 23 1609 1631 1609 1631 0.97

Sequence Information

Coding Sequence
ATGCTTCAGCAGATGTCCTCGCCGGCTGACGCGCAATTCGGCGAGGTCACGACAGTCGCGCGCGCCTTCGAAGGCCGCTTCTTCGGCGACGTGTCCTCTGGCGCTTCTTCGGACACCGCTGAAGATTTTGAGTTGCCTCACTGTAAGATAAGAAGAAACTACAACTGTACAAAGTGCACGTTCTACACTCAAAATCCACGCGCTTATCTGGTGCACACTCGAGACGCTCACTtcgttaaattgaaaatatatgaATGTCCTCACTGCATCTACGCTTCGAGACATAATCAAAAACTTGTGAGGCATGTGAAGATGGTTCACGATAACGTATCTACGCATACTGTCAATAAGGTTGAATTTGAATCGGCACACACAAATGGAATTTCTATGGAAAGCGAGTCACAAGAACAAGATTCAGAGAGAATAGAAGACATGTTAGAAGAGATTGAGGATAATGATGATATACAACTGGATATGGATGACTGTAATGATGATAAAATTGACCGCCCTTGCGAAATGGACATTGAAGCTGAACCTTTTAGACGTGATGTTCCCGTAAAAGGAAAAGAAAACCTCTTTTCCTGCGATAAATGTAATTATGTGACACATTTACGCTCAAGATTTACGAAACATGTAAAATATCATTCAATGCCTATGATAAAATGTGTTGTATGCGACTTCAGAACACCGTACAAATGGAACTTAGATCGTCACATGAAAAACCACGGCGGAGTGGGAAGTTTTAAATGTTCTATGTGCAACTTTACTGCAGATATAAAGCAGAGTTTGACTGTACACGAAATGAATCACCACACGCCACAGGCGGGCCACTCGCACGTCAATCGTCGTCGCAATCGGGTGGGCGCCAGTGACGCAGCACAAGCGGACGAAGCGAGTTTGCTGCTCGTGAAGGAAGAGGATGGGAGCGGCGATTCACGTTCATCACACTCCGCTTCGGAAATGGGACAACAGAACATGGAAAAAGATATGATAGCCTGCAACAGTGATTCAAATGACACTTCTGATGTAACTCACAAGATCTCACATTCTATCTACAATGAACACAGTCAGCAGTCACCAAGTAGCGGCACAGAGGATTCAAAAGGACAAAGAAATAAGAAAACACCTCGACCCTTACCACAACTTATACCTCTTAATTCATCGACGCctaatcaaacaaaaacaagCAACGAACCAcccacaaaaaaaattaaacttgaatCAGATACTGACACAACAGAAGGTATAAGATACCATGCTGACAGTCCTGATATTTTCATGCCTTATACCTCGGTGAAAGATTCTGAAAGTAGAAAGAAAAATGAATCATTCTTTGATAAACTTAAAAAGAGATTGTTAACAGAAACGGGAGAAGAAGGATCTTTGATTTGTAAAAACTGCGGTTTCCAAAGTAAATGCTTGTCTGAACATTCTGTGCATGAAAAGAGTTGCACTCCTTTAGCGAGTAGAAGTATGACCAATACATTACTGCCTAGTTCAGGTTCAACGCGTTGCCAAAATTGTAGACACAGATGTAAATCGAGTGCGGATTTATTTATTCACATGCAAAACTGTGGCAAAAGTAATCAGACACAAAATGAATATACTCAAGACGCAAATGCAACAAACAACACTGCTGCATTAAATCGTGATAAAGATATTGGACCACATCCAATGGAAAACGTTGTTTTTGTTTGGAATAATATTAATCAGGAAACAAATAAATTCGACACACCACTGGATATAAACATTAATGATGATTGCACTCTTCCTGATATGGCACGACACGAAGACATTGAGTTGGTAGATGACAACGACGGCATGAACTTATCTCCCAGTCAAGCAGCgggtaaaaatgtttttaaatgtccACATTGCTCATTCTGGGCATCGACTGCATCCAGATTCCACGTACACATTGTAggacatttaaacaaaaaaccttTCGAATGTTCCATCTGCAAATATAAATCTAACTGGAGGTGGGACATAACAAAACATATAAAGTTAAAGTCCGTAAGGGATCTTGATCATAATGAAGCTAAAGTGTTGATGACTGACGAAACGGGACGAAGAAACTATAGCAAATACACAAAATTTTTAGCAATACCTGTAACTAAAGAAGGTGGAAAAACCGAATTTCGATATCTTGATCTTCATACCTACGTTGACGATTCAATGGATGTGGACGATACAACCGAAGAGTATAATGAAACTTCTACGTATGATATGCAACCACTAAATCTTCAAACTAAACACTTCGATTTCCAAGCTTCTCTTGACTCGAGTGATCAACAAGACAAGAAACCTAAAAAGACACTTTGGAAATGTAAAAAATGCAATTACAAAGATTCATCAAAGGATGCATTATTAGAGCACGTTCGTGAACACACTAAAGGCGAAAACCCCGATGAAACACGGAACAAGAAACCAGAAAACTCAATAGATCCAGCTGACTTAGCATATCGTTGTGGGCATTGTCATCAGTTATCGAACTGGAAACACGTAATACAGCGCCACTGTCGTTTGAAGCATAACGGCATCATCAAAGTCATAACAACAGTCAAACAGAAACCAGAATCGAACGCGATTTCTACGGGATCATTAACCATTGACGACATCACGTCTGACTTCTGCACGAAATGTCCATTCAAATCGAACGACAAACAAGTACTCCTACTTCATTATCAACAACATGAACCATCAACGAGTTCTGTATTCAAATGttatttttgtccatttttcgttaaaaatgaaaatgaattagTGCAGCACCTGCATGTGCATGGTGTGGATGATCCAGAAGATTTTATCTCTAGAGCTATGGGATGCAGATCGCCAGTAATCGATCCTCAGTCCGGTCTGCCTCAACCCGCAGGTGCAGCTAAACGGCACAAATGTTCTGAATGTCCATATGAAACCAATAGCAAATCTCAATACATGTATCATGAACAATTCCACCGCTTGCCAGCAGATACACCGTACAAATGTCCGGAATGTAACTACAGTGTTTCAAAAAGACATCTACTTCATCAGCATTTGAGAGTTCACGGCATTATTCCCAAGAAAAACGAGAGTGAAGCTGAGTTGGAATCGATGTTAGGCCAAAGGTCAGATGATACATGTGATGATATGTCCAATTATTTCAATGAAATTCCTCTCGTTTGGGTATCTGCAAAAGATGAGTTCCACAAAATGTACAAATGTCGTTATTGTTCTTACGTAAATTCTCAAAAATGTAAAATTCCAGTTCATGAGAAAATTCATTGCATTATTTTCGAAAACGATGCATCGGTTTACTACAAATGCTCCGAATGTAAATTTACTTTTGACAACGCCGTAAAGCTTTCTGAACATTCAAAATCACACGGTGATTTATACGGGCGGATTTACTGCCTCGTCACAGATGACATTCCTGATGATGAACAAGTGGCTAAATTACGTAAAGTTCTCGAACTCGAAAAAACTGGAATTAATGAGACTTCGTCTCTTCACGAAGAATTGGGCGAAAGCAAAGAAAAACTCTTATATTTCTGTCAACAGTGTCCCGCACATTACTTTACAGACAGTGAATTACAAGTACATGACAAAAATCATAATGCAAACCTTTCAATCAAGTGCAAAAACTGCAGTTTTGCCGTATCTCAGGATAGTGAATTGATTTTACATGCTGTTGTTCACTCTGACGAATACCACACAAAAACTAGAATGCTTAAATTCGCACACAATTCTCATCCGGCCCACAGAGCACCGATTCTTGAATGTATTCGTACTGAAAGCGGTACAGAAATTTGGGTGATAAACCATAGCAAGAAAAATGAAGTTCTAGAAGTAAACACTCCCAAAAAACCGCAAGAAGTTAAACACACACCTAAACAATATAATTGTAAAGAATGCCCTGCCAAATTTTTTAAAGGTTCGGCTCTCAATTATCACATGGGTTTGCATGGTGGTGAAGGTGAATACAAATGTAAAAGTTGTAGTTATGCAGTTAAGAATGTTGGTAATTTGGCAAAACATGAAGCTTTACatgaaaaggaaaataaaaactCTAACGGTGATTACGAATCAGGAGACGATGGCGATTACAAAAACATTCCACTTTCGGGCACTGATTTATTCCAGAGAAAGACTGAAGCTCAGAAAAGAGTACTAACTGATAAAGATAAATTAGTAAAGCCCAATGACCATTTTCCTCCTGTGCTTCAAGCGGATCCGCAATTTGGATTTTTGATGCATGGTAATCCAGAATTCATTTACCCAACTTATCTCAAAAATGGACGACAAAAAGAAAAACGATACAAGTGTCATAAATGTCCATCTGCGTTTGAAAAAAGAGAACAGTATAAAATACATTTGTCTTTACATGGCTCCAAGCAGCGATACAAGTGTGAACTATGCGATTACTCTGTTAAGTATTATGCTAACTATGTCCAACACATGCGGAAACATCAAATGAATGATGAAGCGCAAGCTGAAAGAAAGAAAGGTGGTAGTGGATTTTTAGGAACGGAACCCCAAAGTGCAGAAACTATGAACGAACAGGAATGCACTGAAAACCCAAAAATGGCCGTCAAAACTATCCCAAAAACAGATTTCCAACAATTTTCATACAGAGATCAACAAACATTGCGTCTTTTACAACGAAGACGATCAAATTCTTCTTTTAATAAGGATATAAGTACAAACGAATCTGTTGTGAACAAGCGGAAACTACACTCTTGTCTTCTATGCCCATATACGAATCATCGTCAGGATGCtttaaataatcattataaaagACATGACGATACCGAAATTGCCAGCATCCCTAACGCGGCAAATCATAAATGTAATTATTGTGACCTGATTGTCTTGCAATCACATTTCTTGAAAGAACATCTGAAAACCCACTTTAACTATCAAAAAACCCTAACTCCCGAATGCTTTGTTGCAAACGAAAATGTTAGTTTTACCATAACGAAAGCTGATAATGAAAGTCAGCCATGCGATCTCAAATtagatattgaaaataaaaacttgacgTGCAATGATGTGAAAATGTTTGTAAACATTAAAACTGGCGAATTAGTGGTTTAA
Protein Sequence
MLQQMSSPADAQFGEVTTVARAFEGRFFGDVSSGASSDTAEDFELPHCKIRRNYNCTKCTFYTQNPRAYLVHTRDAHFVKLKIYECPHCIYASRHNQKLVRHVKMVHDNVSTHTVNKVEFESAHTNGISMESESQEQDSERIEDMLEEIEDNDDIQLDMDDCNDDKIDRPCEMDIEAEPFRRDVPVKGKENLFSCDKCNYVTHLRSRFTKHVKYHSMPMIKCVVCDFRTPYKWNLDRHMKNHGGVGSFKCSMCNFTADIKQSLTVHEMNHHTPQAGHSHVNRRRNRVGASDAAQADEASLLLVKEEDGSGDSRSSHSASEMGQQNMEKDMIACNSDSNDTSDVTHKISHSIYNEHSQQSPSSGTEDSKGQRNKKTPRPLPQLIPLNSSTPNQTKTSNEPPTKKIKLESDTDTTEGIRYHADSPDIFMPYTSVKDSESRKKNESFFDKLKKRLLTETGEEGSLICKNCGFQSKCLSEHSVHEKSCTPLASRSMTNTLLPSSGSTRCQNCRHRCKSSADLFIHMQNCGKSNQTQNEYTQDANATNNTAALNRDKDIGPHPMENVVFVWNNINQETNKFDTPLDININDDCTLPDMARHEDIELVDDNDGMNLSPSQAAGKNVFKCPHCSFWASTASRFHVHIVGHLNKKPFECSICKYKSNWRWDITKHIKLKSVRDLDHNEAKVLMTDETGRRNYSKYTKFLAIPVTKEGGKTEFRYLDLHTYVDDSMDVDDTTEEYNETSTYDMQPLNLQTKHFDFQASLDSSDQQDKKPKKTLWKCKKCNYKDSSKDALLEHVREHTKGENPDETRNKKPENSIDPADLAYRCGHCHQLSNWKHVIQRHCRLKHNGIIKVITTVKQKPESNAISTGSLTIDDITSDFCTKCPFKSNDKQVLLLHYQQHEPSTSSVFKCYFCPFFVKNENELVQHLHVHGVDDPEDFISRAMGCRSPVIDPQSGLPQPAGAAKRHKCSECPYETNSKSQYMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIIPKKNESEAELESMLGQRSDDTCDDMSNYFNEIPLVWVSAKDEFHKMYKCRYCSYVNSQKCKIPVHEKIHCIIFENDASVYYKCSECKFTFDNAVKLSEHSKSHGDLYGRIYCLVTDDIPDDEQVAKLRKVLELEKTGINETSSLHEELGESKEKLLYFCQQCPAHYFTDSELQVHDKNHNANLSIKCKNCSFAVSQDSELILHAVVHSDEYHTKTRMLKFAHNSHPAHRAPILECIRTESGTEIWVINHSKKNEVLEVNTPKKPQEVKHTPKQYNCKECPAKFFKGSALNYHMGLHGGEGEYKCKSCSYAVKNVGNLAKHEALHEKENKNSNGDYESGDDGDYKNIPLSGTDLFQRKTEAQKRVLTDKDKLVKPNDHFPPVLQADPQFGFLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKGGSGFLGTEPQSAETMNEQECTENPKMAVKTIPKTDFQQFSYRDQQTLRLLQRRRSNSSFNKDISTNESVVNKRKLHSCLLCPYTNHRQDALNNHYKRHDDTEIASIPNAANHKCNYCDLIVLQSHFLKEHLKTHFNYQKTLTPECFVANENVSFTITKADNESQPCDLKLDIENKNLTCNDVKMFVNIKTGELVV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00236281;
90% Identity
-
80% Identity
-