Tvar016012.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Trilocha varians
Gene Symbol
RHOBTB1
Assembly
GCA_030269945.2
Location
AP028274.1:8061917-8075120[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2e-07 8e-05 23.4 0.1 3 44 256 296 254 313 0.85
2 3 7.1e-06 0.0029 18.4 0.1 47 107 394 453 385 456 0.81
3 3 2.4e-20 9.8e-18 65.0 0.2 6 108 480 581 476 583 0.93

Sequence Information

Coding Sequence
ATGGACAACGAGCAACCGCATCAAGAGCTTGTTAAATGCGTAGTCGTCGGCGACACAGCCGTTGGGAAGACGCGACTAATATGTGCAAGAGCCTGCAACAAACATGTCTCCCTCTCTCAGCTGATGACAACACATGTGCCCACTGTCTGGGCTATTGACCAGTACAGGATTTATAAAGATGTTCTAGAAAGATCCTGGGAGATGGTGGATGGTGTAAACGTGTCGTTACGTCTTTGGGACACTTTTGGTGACCACGAAAAGGACAGAAGATTTGCGTATGGAAGGTCTGATGTGGTTCTGTTATGTTTCTCAATAACAAACCCTATATCATTGAGGAACTGCGGAGCGATGTGGTATCCAGAAATCAGGCGTTTTTGTCCGAACACACCTATCCTGCTCGTTGGCTGCAAGAACGACCTTCGCTACATGTACAGAGATGAGAACTACCTGAGTTACTGTAAGGATCGAAGCCCTTTCATTAGAGCTCCAAGAAAATGCGACCTAGTAATGCCGGACCAAGGTAGAGCTTTAGCCCATGAGTTCGGGATCTACTATTACGAGACCTCGGTGTTCACCTATTACGGGGTCAACGAGGTTTTCGAGAATGCCATCAGGGCGGCATTGATAGCCAGAAGACAGCAACGGTTCTGGATGACGAATTTGAAGAGAGTGCAAAGACCATTACAGCAGGCGCCGTTCAGACCTCCAAGGCCAGTTGAACCTGAAGTAACTTTCGTCAGCAGCACCTACCTAGAGAACATGACCAATCTACTACAGCAGCAGTATTTCTCGGACATGGTAATAATCTGCGGCTCGAAAGGGTTCCCAGTCCACCGAGTAATGATGGCGGCTGCTTGCGAAGTGTTCTACCGGCTTCTCATCATGGATTGCGAGAGTCTATCCGTGGACCTCGCTAGGAGTTCCAGCGAGAGTAGTATGGTAAGCAGTATAGGTGAAGCTCCACCAGGTGAAGTAAATGAAGACACGGAACATCTTCTCAAACAAGACATCATCAAGCAAATGAGATTGTTAGACCAGATCAGGCGTAGGTCGTCGTGCCAAATTTTACCGTTGAGTGACGGGTGCAAGAAACCACCGGATTTATACAGAGAAGTCAACCATCCCGCTGTCAACTCTATACGGGTTGTAAAGTGTGACAAACTTCAGCACGCTACATCTCAAACTCAAACTATAGCCACTATGAGTAAACTGATCTCACAGGGGGTCATGCAAGAGATCCTCAACTTTATATACACTGGGAAGATGAAGTGTACTTCAGTTAAACGAGAGgaaatcCGCCAAGCATCCGAACTACTGGGGATCCCAGAACTGACGAGGACTAGTCAGTTGATTCTCACACAGCAGATGCTGTATGATGAAGGGTTCCTTCTACAGTTTCATGTGTCGATCCCAAGACGTTTAAGAGACATGTACGTGGAACGCAATACATTTGCTGACGTAACGTTTGCGCTGGATGATGGCATACATCTCGCGCACCGAGCTATCTTGATGGCGCGGTGTGATCCCATGAAGGCGATGTTCCAGGGACATTTCAGGGAGAGCAATTCTAGGGTTATATCACTGCCAGGTGTGAAAATATATGCTTTTCACATCCTTCTATGTTATATGTATACCGATAAAATACCAAGCGTGGAGGCTACCAGGTGTTTGGAATTGTTGGAATTAGCCAATAGATTCTGCATGAACCGACTTGTCAATTTAGTGGAGTATAAGGTCATTGAGGAATTGAGACACAAAGACAgagtTCGTGGTCATGAAGACGAGGTGGTAGAAATATCCTTATTTCTTTTGGAGCCGGCTAAGTTACACAACGCACATAATTTATCAGAATGGTGTCTATGGCGACTATGTGGTTCGTACGACAGAGTATGTCGTGACAAAACACTGTCGCCAACTGTGAGGGAATACCTTGCTGAAAACAGATACCCTCCTGTctgGTACGTCAAAGAATTCGACTACTACCAGAAGTGTTTGAACGAGCAGtcgaaagaaaagaaagaaatggCTCCTACCACGTCAATTCACACAACGCAGCAGACTGGATGTCTTTGTTTTCCTAGTAAAGTACGAAGGTCTAGTGACACAGTGGTGGAGACCCGTGCTCTATGCTCGGCGGTCGCTCTCCCTGTACAAGAGCCGCCGATCTGA
Protein Sequence
MDNEQPHQELVKCVVVGDTAVGKTRLICARACNKHVSLSQLMTTHVPTVWAIDQYRIYKDVLERSWEMVDGVNVSLRLWDTFGDHEKDRRFAYGRSDVVLLCFSITNPISLRNCGAMWYPEIRRFCPNTPILLVGCKNDLRYMYRDENYLSYCKDRSPFIRAPRKCDLVMPDQGRALAHEFGIYYYETSVFTYYGVNEVFENAIRAALIARRQQRFWMTNLKRVQRPLQQAPFRPPRPVEPEVTFVSSTYLENMTNLLQQQYFSDMVIICGSKGFPVHRVMMAAACEVFYRLLIMDCESLSVDLARSSSESSMVSSIGEAPPGEVNEDTEHLLKQDIIKQMRLLDQIRRRSSCQILPLSDGCKKPPDLYREVNHPAVNSIRVVKCDKLQHATSQTQTIATMSKLISQGVMQEILNFIYTGKMKCTSVKREEIRQASELLGIPELTRTSQLILTQQMLYDEGFLLQFHVSIPRRLRDMYVERNTFADVTFALDDGIHLAHRAILMARCDPMKAMFQGHFRESNSRVISLPGVKIYAFHILLCYMYTDKIPSVEATRCLELLELANRFCMNRLVNLVEYKVIEELRHKDRVRGHEDEVVEISLFLLEPAKLHNAHNLSEWCLWRLCGSYDRVCRDKTLSPTVREYLAENRYPPVWYVKEFDYYQKCLNEQSKEKKEMAPTTSIHTTQQTGCLCFPSKVRRSSDTVVETRALCSAVALPVQEPPI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00235958;
90% Identity
iTF_00236731;
80% Identity
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