Basic Information

Insect: Trichopria drosophilae
Gene Symbol: Hr39
Assembly: GCA_030407085.1
Location: CM059586.1:92220465-92225130[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.17 8.1e+03 -1.8 0.0 147 187 64 106 41 136 0.72

2 4 0.55 2.6e+04 -3.4 11.5 62 162 212 326 180 351 0.42

3 4 2.9e-08 0.0014 20.5 0.0 1 22 508 529 508 537 0.90

4 4 5.6e-74 2.7e-69 237.0 0.0 87 408 564 868 533 868 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.17	8.1e+03	-1.8	0.0	147	187	64	106	41	136	0.72
2	4	0.55	2.6e+04	-3.4	11.5	62	162	212	326	180	351	0.42
3	4	2.9e-08	0.0014	20.5	0.0	1	22	508	529	508	537	0.90
4	4	5.6e-74	2.7e-69	237.0	0.0	87	408	564	868	533	868	0.87

Sequence Information

Coding Sequence: ATGTCAGAGCAAGGCGGGCCTACGGAGGGCCCGGGCTGGTGGCCTCCGGCGCAGTCCTGGAAGTCACAATCGACCATGCCGACCCGCACCGCGGAGGCAGGGAAGAACGTCTCTGTCACGACGATTAACGTACCGCCAGCGCACGAGATGCATGACGGTAAAAGTGTTAAGTATTTAGGTGGTCAAAATGGCGTGACCGTATCAGTTGTGTCGAGCTGCAGTTCGTCAACGAATACCGTTGACTCGAGCATCAACTCGACGGTACCACCTCATATCGACGATCTCGATGATAGTGACGGAGAAATCAGTAAAATTGATTTTCGCGGAGTAAATCTTCGAACAAAGAAGAAAAGAGACAGGTCAATAACGCACGATAAAGAAAATGGTAGCGATATCATGCATCAACAGCCAGAGAGACCAATGTCTTGGGAGGGTGAGCTATCTGATCAAGAAATGTCTTCCAATACAATTACTAACCAGGACCTTGAGGAAACGTCAATGGAAGGAGTCCAAGTATGCAGTTCGAGCCCAGGACTTCAAGAACACAAATTTCCTATTAAACCCGAGCCGGACTTTCGGTCAAGTCCAGGACTCGCTTTAGGAACTTCACTAAACGAGACCATTGTACCTTTAACACACGCACAACAGCTTCAACAACAGCAGCATCGACAGCAACATCAGCAACGGGGTGCTGAAAGCCATGAACAAGCACAGCAAAGCGATCTGCCCTTACTCGTTGGCAAGCTTCTTGGTGGTTATAATTGTTCTACACCGAATCATAGCCCAGTACTCAATCCTAGACACCATCTCACAAAACACAGCCATACGAGATCTCaaGTACCGTCTCCGGATTCAGCAATTCACTCGGCCTATAGTGTATTCAGTTCACCTACTCAGAGTCCCCATGCGGCAAGGCATTCGGCTCTTGGTCCTGGCAGTCCAGTGCCTTCGTCGTCACTGTCGATGTCTCGTCATAGTTTCAACAATTCCACATCATCATTGTCTTTGTCATTGTCTCATTCCTTGTCACGAAATAATTCCGATGCTTCGAGCAGTTGCTACAGCTACGGTTCGCTTAGTCCACCTACACATTCACCTGTACAGCAACCGCGACACGCCCATCCTCAGCATCATCACCAGGTGCCACAAGGTAGCCCACTACATCTTTCCACGTCTTCGGGAGGTTCGAGTCATCATTACTCAACGCCTGGTTCCGAAGTTTCATCGGAAGGTCACTTGGACGACCAGGACGACTGTCGGATACCGTCGGCCCCGTCCGGAATCTCAACAAGGCAACAGTTGATAAATAGCCCGTGCCCGATATGCGGAGACAAAATTAGTGGCTTCCACTATGGAATTTTCTCTTGCGAGTCTTGTAAAGGGTTCTTCAAACGAACGGTACAAAACCGTAAGAATTACGTATGCCTTAGAGGGGCAAGGTGTCCCGTGACAGTAGCGACGAGAAAGAAGTGTCCAGCCTGCCGCTTCGACAAGTGCCTGAACATGGGAATGAAGCTCGAGGCAATAAGGGAGGATCGAACTCGAGGAGGGAGGAGTACCTATCAATGCACTTATACGCTCCCAGCGAATCTTATGGGGAGTAACGCGGGTGGCATGACGGGCGATAAGTTGTCTAGCGGCGCATGCAGTCCCGCTCCTCCAGGCTCCGAGCATCACCATTCGATGAAGCATCACTCAAATCATTCCCATAAAATGCAAGTAGTGCCACAGTTATTGCAGGACATCATGGATGTCGAACATCTCTGGCACTATAACGACAATGACAGACTAGGAGGCCAGGGAATGAATTCCTCAGGTTGCCCTAGTGGCAGCAGCAGTGCTGATTCGATTAGTGGTAGTTCGAATGGCCTAAGTAGTAGCGTCAATGGAAACATTAACCGTAGTGAGCCGCCAAGACCAAGTTCTACAGATTCCGCATCCACAAACCACGAACATCAGCATTCGCCACCGGCGTCCGTATTGAATCCCCCAACCAATAACTCGACGCAGCAACCGGACTTCTTGTCCAATTTGTGCAATATCGCCGATCATAGACTTTATAAAATTGTCAAGTGGTGCAAAAGCCTCcctcttttcaaaaatatctccaTCGATGATCAAATATGTTTGCTGATCAATTCGTGGTGcgaattgttattgttttcatgTTGCTTTCGAAGCATGAGCACTCCTGGCGAGATTCGTGTATCCCTTGGTAAGTCAATTACTCTGGAACAAGCGAGGCAACTTGGTTTAGCTACGTGTATCGAACGGATGTTAGCCTTCACGAATAACCTTCGGCGGCTTAGGGTGGATCAGTATGAATACGTCGCAATGAAGGTTATAGTGTTGTTGACGTCCGACACAAGTGAACTTAAAGAACCTGAAAAAGTAAGAGCTTCGCAAGAGAAAGCCTTGCAAGCTCTGCAGCAGTATACGATCGCAAGGTACCCTGAGATGCCTGCCAAGTTCGGGGAGTTACTTCTAAGGATTCCAGATCTGCAAAGAACATGCCAAGCCGGCAAAGAGTTACTAAGTGCAAAACGTGCCGAAGGCGAGGGTAGTTCTTTCAATCTCCTGATGGAACTTTTACGAGGGGAccactga
Protein Sequence: MSEQGGPTEGPGWWPPAQSWKSQSTMPTRTAEAGKNVSVTTINVPPAHEMHDGKSVKYLGGQNGVTVSVVSSCSSSTNTVDSSINSTVPPHIDDLDDSDGEISKIDFRGVNLRTKKKRDRSITHDKENGSDIMHQQPERPMSWEGELSDQEMSSNTITNQDLEETSMEGVQVCSSSPGLQEHKFPIKPEPDFRSSPGLALGTSLNETIVPLTHAQQLQQQQHRQQHQQRGAESHEQAQQSDLPLLVGKLLGGYNCSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGPGSPVPSSSLSMSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHAHPQHHHQVPQGSPLHLSTSSGGSSHHYSTPGSEVSSEGHLDDQDDCRIPSAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGARCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLMGSNAGGMTGDKLSSGACSPAPPGSEHHHSMKHHSNHSHKMQVVPQLLQDIMDVEHLWHYNDNDRLGGQGMNSSGCPSGSSSADSISGSSNGLSSSVNGNINRSEPPRPSSTDSASTNHEHQHSPPASVLNPPTNNSTQQPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00676835;
90% Identity: iTF_01489411;
80% Identity: iTF_01488774; iTF_01488605;