Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.016 6.8 6.4 0.1 26 48 174 196 168 201 0.89

2 6 0.048 20 4.9 0.0 26 48 202 224 197 229 0.89

3 6 0.0024 1 9.1 0.1 26 48 230 252 225 257 0.90

4 6 3 1.3e+03 -0.9 0.0 27 48 262 280 252 282 0.66

5 6 5 2.1e+03 -1.6 0.0 25 48 285 308 279 311 0.80

6 6 0.0021 0.86 9.3 0.0 25 48 313 336 290 336 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.016	6.8	6.4	0.1	26	48	174	196	168	201	0.89
2	6	0.048	20	4.9	0.0	26	48	202	224	197	229	0.89
3	6	0.0024	1	9.1	0.1	26	48	230	252	225	257	0.90
4	6	3	1.3e+03	-0.9	0.0	27	48	262	280	252	282	0.66
5	6	5	2.1e+03	-1.6	0.0	25	48	285	308	279	311	0.80
6	6	0.0021	0.86	9.3	0.0	25	48	313	336	290	336	0.85

Coding Sequence: ATGGAATCTGGTGATTTATTCGATCCTGCTataacagtgaaagaagAGCCTCGGCATGAGCTTCTCGATAATAATGTTTATGACATAATTGACACGACTCTTGCAGTTCCTCAAAATGTTAAATACGAGAAGTCTTGGcatgaaaattcaaCCCAGGAGCTTCTTCAGGAATATGACGAAAATCACGAAAATGAACTCGACGACATTCAAATCGAATTGGAATGTACCGACACGAAGCCCAATTTATTGGCAGTAtcgaaaattgaagatttctCTCCAAATCAGTTTCAGGATAGCAATGATTACAAAACTgaaagcaaaattaaattagaaacTTTCGGGacagtgaaaaaagaaatttttagtGAAGAAGCCACTGTGATTAAAGTTGAATGTGTTTCAAAAAGTATGAACTGTAAACATAGTCTCGAAACTCAAATTGACACTGCGCATAATGGAATCACTCCTGCAAGTCATCTAAAAAGACACGTCGATGCAGTCCGCAAAGATGTCACGCACGCATGTGAAATATGCGGCAATGTATTCAAACGAACAGTTGATCTCAATAggcacatcgattcggtgcataacaGTGTCCGCCATGCATGTGAcatttgcggaaagacataCTCAGacaagagtaatctcaaacgtcacatcgattcgatgcatAATTGTGTCAGTCacgaatgtaatatttgcggAAATGTTATTAAACATAAAGGCGATCTCAAACgtcacatcgattcggtgcataatcaAGTCCGACaagcatgcgataaatgcccaaagacattctcagtcaaaagtaatctcaaaaaacacattgacGCAGTACACAATGAAATCACCCAAGcatgtgatttttgtgaaaaaaaatttaaatatcaaacTCAACTCAATAGGCATGTCAAATCGTCGCATAATGACATCACTTATAAATGCAAGATATGCGGAAAAACGTTCGGACAGAAACGAAATCTGAAAGCTCATATCGATGTGGCTCATTGA
Protein Sequence: MESGDLFDPAITVKEEPRHELLDNNVYDIIDTTLAVPQNVKYEKSWHENSTQELLQEYDENHENELDDIQIELECTDTKPNLLAVSKIEDFSPNQFQDSNDYKTESKIKLETFGTVKKEIFSEEATVIKVECVSKSMNCKHSLETQIDTAHNGITPASHLKRHVDAVRKDVTHACEICGNVFKRTVDLNRHIDSVHNSVRHACDICGKTYSDKSNLKRHIDSMHNCVSHECNICGNVIKHKGDLKRHIDSVHNQVRQACDKCPKTFSVKSNLKKHIDAVHNEITQACDFCEKKFKYQTQLNRHVKSSHNDITYKCKICGKTFGQKRNLKAHIDVAH

Sequence clustering based on sequence similarity using MMseqs2