Basic Information

Gene Symbol
-
Assembly
GCA_034770305.1
Location
JAPMIB010000080.1:199773-201262[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 7.8e-08 2.9e-06 28.2 1.7 1 23 115 138 115 138 0.97
2 12 9e-06 0.00033 21.7 1.9 2 23 144 166 144 166 0.95
3 12 0.0034 0.12 13.6 4.7 1 23 171 194 171 194 0.96
4 12 1.6e-05 0.00058 20.9 3.3 1 23 199 222 199 222 0.95
5 12 6.2e-05 0.0023 19.1 0.1 1 21 227 247 227 248 0.94
6 12 8.4e-06 0.00031 21.8 3.4 1 23 255 278 255 278 0.91
7 12 3.5e-05 0.0013 19.8 0.9 1 23 283 306 283 306 0.96
8 12 2.8e-05 0.001 20.1 0.7 1 23 311 334 311 334 0.96
9 12 4.9e-07 1.8e-05 25.7 1.0 1 23 339 362 339 362 0.91
10 12 1.5e-05 0.00056 21.0 0.7 1 23 367 390 367 390 0.96
11 12 9.8e-05 0.0036 18.4 1.3 1 23 395 418 395 418 0.89
12 12 1.8e-05 0.00067 20.7 1.0 3 23 425 446 424 447 0.96

Sequence Information

Coding Sequence
atgaatagagttAAAAACTTTCATCTCTTACCAATTACGGCAGAAAATTCTacCCATACCCTTCGAACTTCTAACGTAAATTATGATGACGAAGTGGAAATAGTCGTTGAATGTGAAGACGTCAAGCCtgacattaatttattaacaGTTAAGAAAATTGGAGAAGATTCTCAGAATTTCTTGCAAAGCATAAAAGATGTCAATGGTGACATAactcaaaacaaaatgaaaaaagaagtctTAGAAAAAAGTCTAACCATGatcatggaaaaaaaacaccGATTCATACGTTGCATAGTAGAAGCATCCACACGTGTGACGCATATGCACAATGGTATCACTCatgaatgtaatatttgcgGTAAGACATTCACATCGAAAGGTTATCTTAAAACTCACATCAATACAGTGCACAATAGTGTCAGCAACACATGCGCTACGTGCGGAAAGTCATTTACACATAAGAGAAATCTGAAAGTTCACGTCGATACGGTGCACAATGGTATCATACATtcatgtgatatatgcggaaaaaaatgtttaactaAGAGTAATCTGAAATACCACCTGGATACATCACACAATGGCACCAaacatgcatgtgataaatgtggcaaattattttcacataaGTCTACTCTTAAAAATCACATCGATAcagtgcacaatggtgtcaaatatgtatgtgatatttgcggaaagaaattgtCAACAAAAGGATATCTTCAAATGCACATTGATACAGTGTACAATGGTATCACACATTCATGTGATATATGCagaaaatcattttcacaTAGATCCAATCTCAAAACGCACATCGATGATATCCACAATGGTATCACACATCCGTgtaatatttgcggaaagaaattgtCAACAAAACAGTATCTTCAAATGCACATTGATACAGTGCATAATCATATCACACattcatgtgatatttgcggaaagaaattgtCAACAAAAGGGTATCTTCAAATGCACATTGATACAGTACACAATGGTATCACACattcatgtgatatttgcggaaagaaattctcaaCCAAGAGTAATCTGAAAATCCACGTCGAGGCAATGCATAATGACATCACACACCCGTGTAAaatttgcggaaagaaattgtCAACAAAAGGGTATCTTCAAATACACATTGATACGATGCACAATGGTATCACACattcatgtgatatttgcggaaagaaattctcaaCCAAGAGTCGTATCAAAAAACACGTAGATGCAGCACATACAGGCATCACTCAAGCTTGTGGTatttgtgaaaagaaatttacacagaAGATAAATCTCAAAGCCCACCTTAATTCAGTTCATCATTCTCGCATTACAActcaatga
Protein Sequence
MNRVKNFHLLPITAENSTHTLRTSNVNYDDEVEIVVECEDVKPDINLLTVKKIGEDSQNFLQSIKDVNGDITQNKMKKEVLEKSLTMIMEKKHRFIRCIVEASTRVTHMHNGITHECNICGKTFTSKGYLKTHINTVHNSVSNTCATCGKSFTHKRNLKVHVDTVHNGIIHSCDICGKKCLTKSNLKYHLDTSHNGTKHACDKCGKLFSHKSTLKNHIDTVHNGVKYVCDICGKKLSTKGYLQMHIDTVYNGITHSCDICRKSFSHRSNLKTHIDDIHNGITHPCNICGKKLSTKQYLQMHIDTVHNHITHSCDICGKKLSTKGYLQMHIDTVHNGITHSCDICGKKFSTKSNLKIHVEAMHNDITHPCKICGKKLSTKGYLQIHIDTMHNGITHSCDICGKKFSTKSRIKKHVDAAHTGITQACGICEKKFTQKINLKAHLNSVHHSRITTQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01482697;
90% Identity
iTF_01482697;
80% Identity
iTF_01482697;