Tmad001746.1
Basic Information
- Insect
- Tribolium madens
- Gene Symbol
- -
- Assembly
- GCA_015345945.1
- Location
- JADDYM010000096.1:13421942-13431335[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 2.2e-06 0.00015 22.0 0.9 2 23 147 168 146 168 0.97 2 16 0.00023 0.016 15.6 4.1 1 23 173 195 173 195 0.97 3 16 0.00026 0.017 15.5 5.2 1 23 201 223 201 223 0.97 4 16 0.00038 0.026 15.0 0.6 1 19 229 247 229 250 0.95 5 16 1.7e-05 0.0011 19.2 0.7 1 23 257 279 257 279 0.96 6 16 0.0011 0.071 13.6 0.2 1 23 462 484 462 484 0.97 7 16 3.3e-05 0.0022 18.3 7.5 1 23 490 512 490 512 0.97 8 16 8.1e-08 5.4e-06 26.5 2.5 1 23 518 540 518 540 0.98 9 16 0.00041 0.027 14.9 1.8 1 23 546 569 546 569 0.95 10 16 0.019 1.3 9.6 2.2 1 23 581 603 581 603 0.94 11 16 4.3e-05 0.0029 18.0 5.4 1 23 609 631 609 631 0.98 12 16 1.6e-06 0.00011 22.4 0.5 1 23 638 660 638 660 0.96 13 16 1e-05 0.00068 19.9 1.3 1 23 666 688 666 688 0.98 14 16 3.1e-07 2.1e-05 24.7 0.9 3 23 696 716 694 716 0.96 15 16 7.3e-05 0.0049 17.2 0.2 1 23 722 744 722 744 0.99 16 16 0.092 6.2 7.5 0.6 1 23 749 772 749 772 0.96
Sequence Information
- Coding Sequence
- ATGGAGGAGGTCGAATACAACATGAATCGTATTTGTCGCGCGTGCAAAAACGAGTCGTCGGAGATGAGATCGGTGTTTGATGATTGCGAATTGCTGACCGAATGTCCCCGTATTGACGAGATGCTAATGGCTTGTACCTCGGTGCAGGTGAAAGCCGAGGATAGACTACCGAAGATGATTTGCGTCACTTGCACGGAACAGCTCAAAGGGGCCTATATTTTCAAGCAACAATGCCAACAGACCGACGTCAGTCTCAGGGAGTACGTCAAGAATTTCAAATCAGTCGACGATGTCAAGAAGGAAGTGGAGGCCACGGACGGCACTGTCGAAGAGAACCTGGTCGATGTTCTCTCCGAAGAGGACCCCTCGAAAGACTGTCTTACTTCAACTCAACGCTCCGACTTTATCGAATTTATAGAAGACAACCAAATGATTCTGACATGTCGCGAATGTGGTAAAAGCTTCACTCGTCTCGAAGGTTTGCGAAGCCACAAGCGTATCCACTTGGGTACACTTTTCAAATGTCGTTATTGTGGCAAAGGTTACACTAGACAAACTCACGTCTACCGACACGAATTATCTCACGGCAAACACAAACTCCACGTTTGCAGAATATGCAACAAGACTCTAACGAGAATGGAGCATTTAAAACGTCACTTGACGACACATCTAAAAGAAAAACCTTTCTCGTGTAAATCGTGTAATAGAGGTTTTAACAGATCGGATCATCTCGAAGTGCATGCAGTGAGGTGTAAGGGAGAGAGAGTACACATTTGTGACATTTGCAATCGGGGATTTTCGAGAGAGGATAGTCTTGAAGTGCACAAAAGGCTGCATGAGAATCAAAAACCGGCACTGCCAACTCTAGAGAATATAGATAATATCGAGGAGCATTATTACGAGATTGATTACGATCCCAACATGGATTATTCGGCTGGTTCGGATGTTGATGATTATTTAGAGCCGCATGTGGAAGTTACCGAAAATTTAGATGAGGATAGGATTAAGGAAGTGGAAAATTTACAAAACGACGACAGTAATAATAAGGGAGAGTCGGACCAGCAGATGGATATTAAAGATATGTTGGAATCTCAGATTGATCTTGAGATCAATGAAAATGATATCAGTATTGACGAAGATAAAAAAATTATAAGTAGAAGGTTTGAAAGTGACGAGTATGTGCCTGAGCAAGATGACGATATGGAGCTTGGCGTTGCAGACAATGACTCCGACAGCGTGGATTCGGAATACCTCCCAACTAAAGTACGAAAACGTCGCACTAGAGCACGAAAGAACGCTTCCGGTCACAGGAGCACAGGCCGGCCCCGAGGACGCCCCCCTGGCATTAAACGAGAACGCAAAGACACCGATGAAGAAGGCGAATTCCCATGTCCCAGCTGTAACGAGATTTTCCCTCGCATGAGTCTCTTAGACAAACACTCGAAAAGCCACGAAGCCGCCAAAGTCCACACTTGCAAAGTTTGCAACAAGGAATTCTCAAGGTTCAATCATTTGAAGCGTCATATGACATCGCATTCGGTTGTGCGACCTTTTTCGTGCGAAATCTGCGGTAAAAGGTTCTCCAGACGGGACCATTTGCAACAACACGTGAGACTCCATGATAAAAAGCAGGAACACAAGTGCGATATTTGTATGAAGATGTTTAACAGAGCCGATCAGTTGGCCAAACACAAGATTTCGAAACACGAAATGGGGGAGAAAGTGTTGGGCGAGAAAAAGTTCGAATGTCATGTGTGTTTGAAAACCTTCACGACTGAAAAATACCGTGATGTCCACGTGAAAGGCCACTTGGGGGAGAAGCGTTTCCAATGCAAAACATGCGATAAGTCTTTCCTGTCAAAGTCGCACCTAACCGAACACATGAAATTCCACAACGAACATTCAAAAAAGTTCCTCTGTTCAGAATGCGGTCAAAGGTTCATCAGGAACGATTATCTTGTGATTCACATGAGACGACATCGAGGCGAGAAACCTTTCAAATGCAAATTCTGCGGGAAGGGTTTTCCCCGAACCACCGACTTGACGGTGCATGAGCGCTACCATACGGGAGAAAAGACGCATCTTTGTACGATATGTGGGCGCGGATTCGGAAGGGCGTACAATTTGACGGTTCATATGAGGACGCATACGGGGGAAAAACCGTACAGGTGCACGTATTGCGAGGCGGCGTTTGCTCAAGGAAATGATCTGAAAGCACACGTGAGGAGGCATACGGGGGAGAGGTTTCAATGCGAGTTGTGTACGGAGAGTTTTCTCATGGGGTATTTGCTCACGCAACATAAAAGGAGTGTTCACGGTTTGAACGTAGTCAGTAATATAAGGCGCCTTCACCCCATTAACAAGATAAAACAGGACGCGGACGAGCCGCCCCCGATCACTATTCCATTGCCTAAACCGGTAGTACCTGAAATCCTCATTACCAATATCCAAGCCCACTTGAGTCAAATCCAACATCATCAAATCGCTAGAGAATAA
- Protein Sequence
- MEEVEYNMNRICRACKNESSEMRSVFDDCELLTECPRIDEMLMACTSVQVKAEDRLPKMICVTCTEQLKGAYIFKQQCQQTDVSLREYVKNFKSVDDVKKEVEATDGTVEENLVDVLSEEDPSKDCLTSTQRSDFIEFIEDNQMILTCRECGKSFTRLEGLRSHKRIHLGTLFKCRYCGKGYTRQTHVYRHELSHGKHKLHVCRICNKTLTRMEHLKRHLTTHLKEKPFSCKSCNRGFNRSDHLEVHAVRCKGERVHICDICNRGFSREDSLEVHKRLHENQKPALPTLENIDNIEEHYYEIDYDPNMDYSAGSDVDDYLEPHVEVTENLDEDRIKEVENLQNDDSNNKGESDQQMDIKDMLESQIDLEINENDISIDEDKKIISRRFESDEYVPEQDDDMELGVADNDSDSVDSEYLPTKVRKRRTRARKNASGHRSTGRPRGRPPGIKRERKDTDEEGEFPCPSCNEIFPRMSLLDKHSKSHEAAKVHTCKVCNKEFSRFNHLKRHMTSHSVVRPFSCEICGKRFSRRDHLQQHVRLHDKKQEHKCDICMKMFNRADQLAKHKISKHEMGEKVLGEKKFECHVCLKTFTTEKYRDVHVKGHLGEKRFQCKTCDKSFLSKSHLTEHMKFHNEHSKKFLCSECGQRFIRNDYLVIHMRRHRGEKPFKCKFCGKGFPRTTDLTVHERYHTGEKTHLCTICGRGFGRAYNLTVHMRTHTGEKPYRCTYCEAAFAQGNDLKAHVRRHTGERFQCELCTESFLMGYLLTQHKRSVHGLNVVSNIRRLHPINKIKQDADEPPPITIPLPKPVVPEILITNIQAHLSQIQHHQIARE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01410167;
- 90% Identity
- -
- 80% Identity
- -