Tmad000548.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tribolium madens
Gene Symbol
-
Assembly
GCA_015345945.1
Location
JADDYM010000096.1:4884972-4889429[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1e-05 0.00071 19.9 1.8 1 23 132 154 132 154 0.99
2 16 0.00026 0.017 15.5 7.5 2 23 161 182 161 182 0.97
3 16 0.00032 0.021 15.2 3.2 1 23 189 211 189 211 0.97
4 16 0.00094 0.063 13.7 1.5 1 23 273 295 273 295 0.99
5 16 3.8e-06 0.00026 21.3 6.2 2 23 302 323 302 323 0.98
6 16 8.5e-05 0.0057 17.0 4.5 2 23 340 362 339 362 0.97
7 16 5.3e-05 0.0036 17.6 2.6 1 23 423 445 423 445 0.96
8 16 0.00023 0.015 15.7 1.1 1 23 451 474 451 474 0.93
9 16 1.4e-06 9.2e-05 22.6 0.8 1 23 479 501 479 501 0.98
10 16 1.3e-07 9.1e-06 25.8 1.5 2 23 512 533 511 533 0.97
11 16 6.4e-08 4.3e-06 26.8 1.4 1 23 540 562 540 562 0.97
12 16 2e-05 0.0014 19.0 1.6 3 23 574 594 572 594 0.92
13 16 0.00018 0.012 16.0 5.1 1 23 600 622 600 622 0.99
14 16 2.3e-05 0.0016 18.8 3.1 1 23 628 650 628 650 0.98
15 16 5.1e-08 3.4e-06 27.1 0.2 1 23 656 678 656 678 0.99
16 16 0.0001 0.007 16.7 0.2 1 23 684 708 684 708 0.93

Sequence Information

Coding Sequence
ATGATTAATAAAACCACGGAGTTAGTTATCGATAAAATCTGCCGTTCATGTATGTGCCAAAATGAGAATATGCGAAATGTGTTCGATTCCAAAGAACTCGGCGGCCAAACTTTACAACTCGCTGAGATGTTAATGGATTGCGCTGCTGTGGTTGTTGCCTCAGGGGACGGCCTTCCCAACCTTTTATGCATAACCTGTGAAGACAAGCTCAACCTCGCCTACGAGTTCAAACAGCAGTGCCAGAAGACCGACACGACCCTACGGGAACTCACCAACCAATCCGATTCTGTAATCAAGGAGGAAACTTGCGATATAGTCGTTCAGCCCGACTTCAACATCCCAGAACTTTACAATGACTCAGATAGCGATGATGACGACTCCAAGTCTAAATCCTTTACGTGTCCCTTTTGCCAGAAGGTTCTAAGGACGAAAAAGGGTCTCCGCATCCATCAGCGACGCCACACAGGGGACAAACTCCGCTCTTGCCACTTGTGCGACGCTCAGTTTACAAGGACCCACCACTTGATCAGGCACATGAAAACCCACGTGAAGGGCGACACGGGGCACGTGTGTGCCGAATGTGGCATGTCTTTCATGAAATTGAGTCATTTGCTGTCGCATAAGAAGACCCACAAGGGAGATGGGGGCGATAAGAGCGATGAGGGTGAGAGCGGGCAGCAGTCAACAGCAGCGGACAATAACAGCGATTGCGATAATGAAATAACGTTGGAGATTAACGAGGATGAGGACGAGGATGACGCTTTGGAGGAGTATTTTAAGCCAAAGACGAAAACGTCGAAAAAAGATAAAGGAACTTATGAATGTAAATATTGTTTTAAGATTATGACGACGTTTGTCGGGCTTAAGATACACATGAGGAGGCATACGGGGTCAGATTTGGCCAAGTGTAAATTATGTGACAAAAGCTTTACGAAAACCAGCCACCTGAAGCGCCACCTACAAACCCATGGCATTAAAGAGCTCGATAAACCGAAACCTGTCGAAAAGAAGGTAATGGAATGTGAATTCTGCGACCGAAAATTCAAATACAAGAAGAGTTTCAACCATCATATGCAAACCGAGCATGGAATGTCGGACGAAAGCGACGTCCCTCTCAGTGCTTATATTTCAAAAATGAAAGATCCGGAAGAACCTAAAGAGGAGTCGGCTGAAAAACCTGAAAAGACGGACGAGGCAGAGCCGAGTTCGGATCAAGAGACGAAAGAGGAAATTACGCCGCCGACGAAACCCATCCATCACAAAGTCCACGTGTGTCACGTGTGTGAAGCGGCGTTCGCGCGAGCCAATCATTTAACACGACACATGACTTTGCACAGGGCACTCTTGATACATAAGTGTGATAGGTGCGACAAGGCGTATGCGACGTTGGAGCATTTGGCTAAGCATGTGGAAGAGGATCATATTAATAAGCCGTATGCATGTACGATTTGTAATAAGCCGTTTAGTAGGGGGGAGCATTTGATACGACACTTGAAGGTGCATCAAACCGGGAACGAGAAAGAGGATAATTTGACGTGTTCGATATGCGAAAAGACTTTCAGCAGGTCTGATCATTTAGCGCGCCATATCAAGATACATTTGTTACAAGATAAGCGGCATGTTTGTTCTGAGTGCGGTAAAGCGTTCAATAGACTCGATAATCTTAAGACTCACCAGAGGATACATACGGGTATCAAAGACACTACAAAGTTGCACCTTTGTATTTACTGCGGCAAGGAGTTTAATAATTCGAGCAATATGATTGTTCACATGAGACGACATACGGGGGAAAGACCGTATAAATGCAGTCAGTGTGGTAAGGGTTTCCCTAGATCACATGATCTCAAATGTCATGAAAGGACACACTCAGGGGAAAAACCCTATCATTGCGCGTTATGTGGAAAATCGTTCAATAAGAGCAATAAGTTGTTACGCCACACTCGCGTCCACACCGGTGAGCGGCCCTACGTGTGCAACATTTGCGGACGGGCCTTCACCCAATCCAACGACTTGGCCCTTCATATGCGTCGTCACACGGGGGCGCGGCCTTACGCCTGCGGTATGTGTCCGGCGCGTTTCATCCAATCCGGACAACTGAAAACCCACCGACGTACTACGGGCCATTGGGTGGAGACTCAGCCGGACCTGAAAGGGGGCCACCGGGTCGAGCCCGTCACCCCCGTTATGGAACCTACACCCATTAGGTTCAAGACCCATGGCAAGAAGAAGGATGATGAGGTGGACGAAGCAAAGAGCAAAATTTTAGCCCAGACGATGGGGTTAATGGGACCGTTGAACGTCTCAGGGGAGAATCTGGTGATCGATCCAAAAATTGTTGAGTTGCAGAATTCGGGATTGATCAATTTGATGGGCGGAGGGGAGGTTAAGTTTAAAGAGGGTGGGTTTGTGGTGTCGCAGGTGAAGAGTGAAGGGGAAAAGGTTCAAGGGTTTGGACAAGGGGGGTCCGTGACGTACTCGATAGTGGCGCCGGTGGCGAGTTCGACGACTTTTACAGCCGCGGATTATAGCAATTATCAGAATTTCGGTTGA
Protein Sequence
MINKTTELVIDKICRSCMCQNENMRNVFDSKELGGQTLQLAEMLMDCAAVVVASGDGLPNLLCITCEDKLNLAYEFKQQCQKTDTTLRELTNQSDSVIKEETCDIVVQPDFNIPELYNDSDSDDDDSKSKSFTCPFCQKVLRTKKGLRIHQRRHTGDKLRSCHLCDAQFTRTHHLIRHMKTHVKGDTGHVCAECGMSFMKLSHLLSHKKTHKGDGGDKSDEGESGQQSTAADNNSDCDNEITLEINEDEDEDDALEEYFKPKTKTSKKDKGTYECKYCFKIMTTFVGLKIHMRRHTGSDLAKCKLCDKSFTKTSHLKRHLQTHGIKELDKPKPVEKKVMECEFCDRKFKYKKSFNHHMQTEHGMSDESDVPLSAYISKMKDPEEPKEESAEKPEKTDEAEPSSDQETKEEITPPTKPIHHKVHVCHVCEAAFARANHLTRHMTLHRALLIHKCDRCDKAYATLEHLAKHVEEDHINKPYACTICNKPFSRGEHLIRHLKVHQTGNEKEDNLTCSICEKTFSRSDHLARHIKIHLLQDKRHVCSECGKAFNRLDNLKTHQRIHTGIKDTTKLHLCIYCGKEFNNSSNMIVHMRRHTGERPYKCSQCGKGFPRSHDLKCHERTHSGEKPYHCALCGKSFNKSNKLLRHTRVHTGERPYVCNICGRAFTQSNDLALHMRRHTGARPYACGMCPARFIQSGQLKTHRRTTGHWVETQPDLKGGHRVEPVTPVMEPTPIRFKTHGKKKDDEVDEAKSKILAQTMGLMGPLNVSGENLVIDPKIVELQNSGLINLMGGGEVKFKEGGFVVSQVKSEGEKVQGFGQGGSVTYSIVAPVASSTTFTAADYSNYQNFG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01568241;
90% Identity
iTF_01480297;
80% Identity
-