Basic Information

Insect: Tribolium castaneum
Gene Symbol: -
Assembly: GCA_000002335.3
Location: NC:123382-127903[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.036 2.1 8.5 0.1 2 23 215 237 214 237 0.89

2 18 0.00045 0.026 14.5 0.1 1 23 282 305 282 305 0.97

3 18 8.6 5e+02 1.0 0.4 3 20 313 330 312 335 0.84

4 18 0.21 13 6.0 0.1 1 23 343 365 343 365 0.97

5 18 7 4.1e+02 1.3 0.5 3 23 405 427 403 427 0.80

6 18 0.00036 0.021 14.8 4.6 1 23 430 453 430 453 0.96

7 18 0.011 0.63 10.1 2.1 2 23 460 482 459 482 0.95

8 18 0.00012 0.0072 16.3 3.6 1 21 578 598 578 599 0.95

9 18 0.012 0.7 10.0 0.9 2 23 611 633 610 633 0.91

10 18 0.072 4.3 7.5 0.7 1 23 636 659 636 659 0.95

11 18 0.13 7.8 6.7 0.2 3 23 666 686 664 686 0.95

12 18 3.3 1.9e+02 2.3 0.1 1 23 690 713 690 713 0.93

13 18 0.062 3.7 7.7 0.4 2 23 720 742 719 742 0.95

14 18 0.027 1.6 8.9 0.5 2 23 751 773 750 773 0.94

15 18 0.091 5.3 7.2 0.1 3 23 780 801 779 801 0.93

16 18 2.6 1.5e+02 2.6 4.9 3 23 900 921 899 921 0.95

17 18 0.39 23 5.2 0.1 2 23 928 950 927 950 0.92

18 18 0.14 8.3 6.6 0.9 1 23 963 985 963 985 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.036	2.1	8.5	0.1	2	23	215	237	214	237	0.89
2	18	0.00045	0.026	14.5	0.1	1	23	282	305	282	305	0.97
3	18	8.6	5e+02	1.0	0.4	3	20	313	330	312	335	0.84
4	18	0.21	13	6.0	0.1	1	23	343	365	343	365	0.97
5	18	7	4.1e+02	1.3	0.5	3	23	405	427	403	427	0.80
6	18	0.00036	0.021	14.8	4.6	1	23	430	453	430	453	0.96
7	18	0.011	0.63	10.1	2.1	2	23	460	482	459	482	0.95
8	18	0.00012	0.0072	16.3	3.6	1	21	578	598	578	599	0.95
9	18	0.012	0.7	10.0	0.9	2	23	611	633	610	633	0.91
10	18	0.072	4.3	7.5	0.7	1	23	636	659	636	659	0.95
11	18	0.13	7.8	6.7	0.2	3	23	666	686	664	686	0.95
12	18	3.3	1.9e+02	2.3	0.1	1	23	690	713	690	713	0.93
13	18	0.062	3.7	7.7	0.4	2	23	720	742	719	742	0.95
14	18	0.027	1.6	8.9	0.5	2	23	751	773	750	773	0.94
15	18	0.091	5.3	7.2	0.1	3	23	780	801	779	801	0.93
16	18	2.6	1.5e+02	2.6	4.9	3	23	900	921	899	921	0.95
17	18	0.39	23	5.2	0.1	2	23	928	950	927	950	0.92
18	18	0.14	8.3	6.6	0.9	1	23	963	985	963	985	0.96

Sequence Information

Coding Sequence: ATGGAGACGAAACTGTGCCGAATATGCGGAAAACTCGGCCAAAACTACGTGAATATTTTTCGAACCGAAGGCCTGAAGAACAAGATCGAAACATGTCTCCCTATTATTGTGTCGCCCCATTCACTTCTCCCCGATACGATTTGTGGCGAATGCTCAGACAATGTGGACAATTTCTACAGTTTTATCAAGAATTGTCTCCAGAATATTATCATACTTGAAGCCCAATATGACATAAACGAGTCTTGTTTGAAGACAAAACGCAAACATGACAAAGGATGCACCACTGATTTGGCCAGAAAAAGCGACAAAAATACTCAAACTATCGATTATCTTGATCTCCTCCTCAAAGAAAACGAATTGAATTTTCCTAACCTTAAAAAACTGGTCGACTATGACGACTCTGATTCTGAACAAGACGTCAAAAAAGCAGCGTCGATCTTTGATAATTTTGGCCGAAAATATTTCGACGATGCAGAAAACTACCTTATCGACGAAATTACTCAACGTAAAAAGCGCAAAAACGAAGATACAATCGAATCGTCACGTGCAAAAATCTGTAAAATCGAAACAACCAATCGGCGGAAAAACAAACAACCGAAAAAACTCGAAATCAAGAACGATTTTCTAGGAGATTTACCGCAAGTTTGTTTATTATGCGATGAACAATTCACTGGTCCTTCCATGTTGGCTAGTCACGTGTTTGAAACGCACGGCATTGACATGGCGGCCGTTACCGGCGATACTAACGACAAAAAGAAAAAGTTACCAAATCTACTCAAGATTTCAGATCTCAGGAAAAGCGATTCGATCGAAGAAGAGGAGCCGCCGACTCTTCTCCCGAGCTTCGTTTGTTCCCTTTGTCCGGCGATGTTTACATCACGTCCGGACTTGTTTGGCCATCTTCGTGTGAAACATTCCGACCAATCGGCTCTCTTATGTGGCATGTGTCTCTATCAAGCTTCATCATTGGCTAATCTTCAGTCACATGTTGAATTATGTTCCCACCAACATCCAACCACAACAAAATATGTCTGTCAGGTGTGTCGTTATGGTGATGATAATTCCAAATCATTGGAAAATCATATACTCGTCCATGACTTTTTGTTGGATGCGTGTAAAAAACAATCGAAAATGTTCGATCCAGCCGACTATATCGAAACGAATGGTAATTACGAATCGGGTGGTTCGTCACCAATGACAAAAAGTCTAGCGTGTAGTGAGTGCGGAATGGACGATTTTGATAATTTTAAAGAATTTAGTACGCATAGAAGAAGCCAACATTCAATTTTTCATTGCGATCTTTGTAATAAATTTTACGGCCGTAATTCGCATTTATGGAAACATGTCAATCGATTGCATAAAGGACATCCAAGTATCACGTGTCAGTTGTGCTACAAAACGAGTGCTTCAAAGTATCATCTCGCACAACATTTCAATAAAATCCACAGTACGAAGAGCTGCAAAAAGAGCGAAAATCAATTGAATTTTGACAATACGGACGATTTTATGTCACAGAAATTCCAAGCTTTTGATTTTCAATCGGTCAAACAGAGTTTCATGCGACAGGAATTACTCGAACAACAGGAAAAGAAGTTTTCCGAAAACGACGACAACTCGAATAATCATTTATCCGATCAGGAACCACCATCTGCACCTAAAGAAATTGACTCATCTAGTGACCTCTACACTAACATTATTACAAACTATACGCCACCTGCCAACGAAGGCGAATTCAAATGTCCCAAGTGTGGTAAAGGTTTTCACAAGAAAACCCTCCTTAAGAAACACAAAAAGAACTGTAGACCACGTCTCCAGAAAGATTTACTCACTCGTTGCAAATCATGTGCTCGTATATTTAAAGATCGCCAAAGTCTCGCCAAACATTTGGTTAATTACCATTCAGAGTATGCGTGTGAAATATGCGGTCAAAAAGTCCAAAGTAAGTGTGAGATTGTCTCACATATTAGGTTCACACATCCCGGTTGTCATTTGTTTTGTACGATATGTGGTAACATATTACGTAGTCGTAACGATATGGCCGACCACACACGTGACCATATGAATAGTTACGTCTGTCAATTCTGCGCTGATGCGTTACCAAGCAAAATCAAACTTAAAATGCACATTTTAAGTCTACATCGTAAAATATTAAGTTTAAGTTGCGGTGTTTGTTTGAAATTGTTTGAAACGCAACATGTTCTACGCGACCATGTCAGGTTAGTACATCGTGATCAGTTGGCGCCACTGACTTCGTGTCCCGTCTGTGGTAAAAATTACGGTTCAAAATGGAAAACCTACGATCACTTGAATAAGTCACACGGACGTATTTTTAAAGCTTGTAAGGCTTGTCTTGAAGTTTTTGACAATGAAAATCAATTACAAGCCCACTATGATAGTGTACATGGTGGGGGTAAAAACAATATACCGGTCGTAACGTCACAAGTTAGCCAACCACAAAATCACTGTGAGAGTGAAAGTGAGCGAGAAACGAATAGCGAACAAAGTGATGAGCAAGAAGAAGACGAACAATACGATAATAAAATCTCACTATTGGAGAAACGTCTACTTGGGAAAAATGAGAAGGTGTTACCAACCAAAATTAATAATAAAAAACTCAAAGAACTCGATTTTGACACGAATCCGCAACATAACAGTTCAAAACGTACAGTTTACGTCAATAGTAACGATCCGTCATTTTGCGAGATATGTCACAAGACATGGCCTGCTAAGAAACATCTCTGGCAACACTATATCCGGTGTCATAAATCAGTGGCGGCTACGGTTTGTGGCATTTGTCTCAAAACAAATTCCTCCTATGGTGCACTTCAAGCCCACTTGATGGAAACTCATCCAACGCTTTTGCACGGTCAAGGTTTCGGTTCGAATTTTATTTGTCGTATTTGTGGTCGTTATCACAATGCGTCAAGTAAATTAAAATTGCATATGGCGATTCATGAGAATTTTGATTGGTCGATGCTTGAACAACCGAAAGAGGAGAAGAAGGAAGAGAATGGGTTCCAGGATGCGTCTGAAATTAATTACGAGAGTTTGATTGAACAAGTCGAGTGTTCCTCGGGTTCGGAAAGTGAAAATGTCGAAACGAAAGATAAGGAATCAAGTTCGGAGGATGATAGTGATAGTGAGACGAACGAAGCGAGTTCTGTGAGTGAGGAAGAAGAGTCGAGTGGAAGTTGGTTTATGGTTAAAAGTGAAGAGAGTGAGGAGGAAAAGTTGGAATCGGCGATCAGATCGATTAAATATGAGTGCGTGGAAAAGGTAGAGGAGGAGGTGGAGGAGGAATATTGCGATATGCAAGCGCAAAGTTTGAATGATAATGAAATCGAGTCGGCGGTGGGGAGCATATTGTAA
Protein Sequence: METKLCRICGKLGQNYVNIFRTEGLKNKIETCLPIIVSPHSLLPDTICGECSDNVDNFYSFIKNCLQNIIILEAQYDINESCLKTKRKHDKGCTTDLARKSDKNTQTIDYLDLLLKENELNFPNLKKLVDYDDSDSEQDVKKAASIFDNFGRKYFDDAENYLIDEITQRKKRKNEDTIESSRAKICKIETTNRRKNKQPKKLEIKNDFLGDLPQVCLLCDEQFTGPSMLASHVFETHGIDMAAVTGDTNDKKKKLPNLLKISDLRKSDSIEEEEPPTLLPSFVCSLCPAMFTSRPDLFGHLRVKHSDQSALLCGMCLYQASSLANLQSHVELCSHQHPTTTKYVCQVCRYGDDNSKSLENHILVHDFLLDACKKQSKMFDPADYIETNGNYESGGSSPMTKSLACSECGMDDFDNFKEFSTHRRSQHSIFHCDLCNKFYGRNSHLWKHVNRLHKGHPSITCQLCYKTSASKYHLAQHFNKIHSTKSCKKSENQLNFDNTDDFMSQKFQAFDFQSVKQSFMRQELLEQQEKKFSENDDNSNNHLSDQEPPSAPKEIDSSSDLYTNIITNYTPPANEGEFKCPKCGKGFHKKTLLKKHKKNCRPRLQKDLLTRCKSCARIFKDRQSLAKHLVNYHSEYACEICGQKVQSKCEIVSHIRFTHPGCHLFCTICGNILRSRNDMADHTRDHMNSYVCQFCADALPSKIKLKMHILSLHRKILSLSCGVCLKLFETQHVLRDHVRLVHRDQLAPLTSCPVCGKNYGSKWKTYDHLNKSHGRIFKACKACLEVFDNENQLQAHYDSVHGGGKNNIPVVTSQVSQPQNHCESESERETNSEQSDEQEEDEQYDNKISLLEKRLLGKNEKVLPTKINNKKLKELDFDTNPQHNSSKRTVYVNSNDPSFCEICHKTWPAKKHLWQHYIRCHKSVAATVCGICLKTNSSYGALQAHLMETHPTLLHGQGFGSNFICRICGRYHNASSKLKLHMAIHENFDWSMLEQPKEEKKEENGFQDASEINYESLIEQVECSSGSESENVETKDKESSSEDDSDSETNEASSVSEEEESSGSWFMVKSEESEEEKLESAIRSIKYECVEKVEEEVEEEYCDMQAQSLNDNEIESAVGSIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01481241;
90% Identity: iTF_01481241;
80% Identity: -