Tcas000252.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tribolium castaneum
Gene Symbol
ZNF236
Assembly
GCA_000002335.3
Location
NC:14337340-14359447[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.00014 0.0082 16.1 1.4 1 23 99 121 99 121 0.98
2 25 0.00081 0.048 13.7 0.2 1 23 127 149 127 149 0.98
3 25 9.6e-05 0.0056 16.6 0.3 2 23 155 176 155 176 0.97
4 25 0.0061 0.36 10.9 1.9 2 23 183 204 182 204 0.95
5 25 0.27 16 5.7 1.2 2 23 216 237 215 237 0.95
6 25 3.1e-06 0.00018 21.3 1.6 1 23 261 283 261 283 0.97
7 25 0.00094 0.055 13.5 1.9 1 23 289 311 289 311 0.95
8 25 4.6e-05 0.0027 17.6 0.8 1 23 317 340 317 340 0.96
9 25 0.012 0.7 10.0 5.2 1 23 350 373 350 373 0.97
10 25 1.6e-07 9.4e-06 25.3 0.9 1 23 446 468 446 468 0.98
11 25 2e-05 0.0012 18.7 1.1 1 23 474 496 474 496 0.98
12 25 0.0022 0.13 12.3 1.6 1 23 502 524 502 524 0.98
13 25 0.026 1.6 8.9 1.4 1 23 530 553 530 553 0.93
14 25 0.0036 0.21 11.6 0.9 2 23 594 615 593 615 0.96
15 25 1 60 3.9 4.5 1 20 621 640 621 643 0.94
16 25 5.2e-06 0.0003 20.6 1.0 3 23 651 671 649 671 0.97
17 25 0.0019 0.11 12.5 2.9 1 23 677 699 677 699 0.98
18 25 8e-05 0.0047 16.8 2.7 2 23 919 940 918 940 0.97
19 25 5e-06 0.00029 20.6 6.3 1 23 950 972 950 972 0.98
20 25 8.6e-06 0.00051 19.9 2.1 1 23 978 1000 978 1000 0.98
21 25 6.4e-05 0.0038 17.1 1.0 1 23 1008 1030 1008 1030 0.97
22 25 0.07 4.1 7.6 3.9 1 23 1036 1059 1036 1059 0.95
23 25 0.0002 0.012 15.6 2.0 2 23 1190 1211 1189 1211 0.96
24 25 9.4e-06 0.00055 19.8 0.9 1 23 1217 1239 1217 1239 0.98
25 25 0.0069 0.4 10.7 2.7 1 23 1245 1268 1245 1268 0.97

Sequence Information

Coding Sequence
ATGGCTGAAGGAAGTTATATGGATAACATTTCGACTTTTGTCGCCCTACCAGTGGATACTTTGGAAAATAACATCCTCCAAAAACCTGAACAATTTCGCATAATCAAAAATGCAATCATTAAAAAATTATCTGATGGTTCAGTTTGTATTATAGACGCAAATGAGGTTAATGAAGGATTGCCACAAGAAATCGAAGTAACTTATTTGCCCCCTGTTGACGTTACGCCGGTGGCTAACGCCACTCCAGACAAGCCAACAGTAACTGTAAATAAGGAAACTTCACCTAAACAAACATACAAGTGTTCCAAATGCAAGGAAGTGTTCGAAAAACTTGTCTTATATCGAAAACACATGATGTGGCACCGAAGTATAAAAAAATTCAAATGTGAGAAATGTTCAGTAGGTTATAATGTGGAAACAAATTTAAAAATTCATATGGCAATGCATAGTGAAGGGAAGCCTACTTGTCCAATTTGCAATATTTCGTTTCAAAGATTGGCAAGTTTAAAATCTCATTTAATGTTGCATCAAGTTGAGGAATTGTGCACTTGTGAAGAATGTGGAGCTGAATTTGAAAAAGAAGAAGAATTAGAAAAACATTTTCATAGTCATTTGGAAAATACCGCCAAGGAAAATAATAATTTGGTTTGTACTTACTGTAGTGTTCAATTGGATGATCAAAAAAGTTATAAAGAGCACATTTCACATCATGTCAAGGTGAAGAAGATGGTTTTATCGGGAAAAAAATCCCGCAAAACCCACGGCAACAAAGAATACCCTCACGTGTGTAACATTTGTTCGAAAAGTTTTTCGCGAGTTTCGCTCCTGGAAAGACACTCACGTATCCACAGTGGAGAAAAACCTTTCCTTTGTCAATACTGTTTTCGTGGTTTCAACCAAAAAGGCACTCTACAAATTCATTACAGTAAACATACGGGGCATAAACCATTCCAGTGCACTTTATGTTCGGCGAAATTCAGCCAAAAAGGCAATCTTCGGGTACATGTTGAAAAAACACACACAGCGCCTTTACCAGGCGTTAAAATGTATAAATGTTCACACTGCACTTGCATTTTTAAAAAAATTGCCTCTTTGAACGTCCATATCACGAAGTTTCATTCAAACGGCGAAGACTCCACGAGTATTTCGAGTGTAATGAATCAGTTGAAAGAACTGGAACAAGTAGCAATGCCTTCTTCACACAGTGAGACTGTACAGGAAAATGAACGTGTTGACGATCCCAATACAAGTTTTGTCAGATTGGCTGAATCGTTCCTTGATGGAACAGTCAGACGATATTTGGTGAAGCAGAAGAAAGTGAACGATGTCAGATGGTACATTTGTAACTACTGTAACAAAGAGTTCAAAAAACCGTCGGATCTTATCAGACATACAAGGGTTCATACGAGGGAAAAACCATTTGTGTGTAACAAATGTGGTGCCTCGTTTTCCCTAAAAACGAGCCTTTTTTCACACGTTAAAACCCACCTTGGGAATAATAACTACTTTTGTTCGATTTGTATGAAAAAATTTTCGTCGGCTCGTTCGGTTAACTTGCACTTGAGGAGACACTCGGAGAAGCCACAATACAAATGTTTATCTTGCAACAAAAGTTTCAGTTCGATTCAAAAAGCCAAACTCCACTATAAAGAAGCTCACAGTGGACGATCTGAAAAAGACTCGGAAATAATTCTGAAGCAACCTTTAGTTAACACACCTGATGGTTTATTACCAGTGCCACCACCAAAATCCGTACATTCAACAAATTCAAAACAAATCCAATGTCCGATTTGTTGTGTACGATTTAGTAAAGTACCGAATTTAAAACGTCATATGCTGCTACATAACGGCGGAAAAAAGCACAAGTGTGGTCAATGTATGAAGTCGTATTATACAGCTCATGCTTTGAAGGAACATGTGTTGTGTCATTCTGGTGTTAAAAATTTCGGATGTAAAGTGTGTGGGAAAAAATATACAACGGCTTCGTTATTGAAGAGACACACTCTCAGTCACAGTACGAACAAGCCTTATGTTTGTCCATACTGTAGCAAGAATTTTAAAAGTGTTATGTTGTGTCGCAAACATATGAACGTACACAAGAAGGATCTACAGATCACTGTTCAAAACATATCTAATGAAACCAAAAATTTGGATATTGATAAACCAAAGCTACTTCTTATACCTGATTCGATATCCAACTCTGGTTTATTAACAAATAACCAAGATCCTCTAGAAACCACTAATCTCCAGTTAATTACTCAACCAAATGTGAACGAAATTGTGAATCCAACTGACCAACAATTTTATGAAATAACACCAAACTCTATCCAAATAATTACAAACAGTGACAAGGATCTTGTCCAAGATCCCAACCAAATACAGACTATTTTCATCAATTGCGACAATTTACCATTGGGCGATAACTTGTATTCAACGAACACAAATTCAGTTTTGTTTGATCCAATGAATGAAAACACTTTCAATATTAATGCCTTGAATGGAGATTTTTCAACACAAAACACCGAAACATTTAATGATGGACAAACCAATAGCACTTCAACCGATAAAGTTTCGAATGATAATCTCCTAACTACCAACATACCATTGTATCCACAATCTGAACTCAATCTACTGTTCAATCTAGACACTGAATTCGTTTCAAACAATTGCGATTTACCTGATATTAATATAAACGAAGTGCCTGACTTAAACGTCGAACCTGCGAAAGAAAACGACGAAGCGAAAAATCGAATGACTTGCGATAAATGTAGCAAAGTGTTCACTAACAAGAAAACTTTTTTGAAACATGTTAACAGCCACAAAGACCGGCAAAAAGTCGCCGGTTTCCACCAGTGCAGTTTCTGTGAGAAAAGCTTCAAGAAACACTCTGATTTGATACGCCACATTCGCACACACACGGGGGAAAAACCGTTTGCTTGTGACAAGTGCGAGAAAAAGTTTTCACTAAAATCAACTCTATTGTCGCATCAGCGCACTCATAATCCGATCAGTCACAAACAGTTTAATTGTGTCGTTTGTAACTCATTTTTCACGTCAAAGTCTAGCCTCAAGGTGCACATGAGTGTGCATACAGGTGATAAAAGCTATAAGTGTAGTTTTTGTTCGGCTAAATTCCGAACGGCGGCTCATCGAAAATCGCACGAGAATAATTATCACGTGAATCCGTCAAAGAAGAAAACGAAAAACAAAGTTACGAATTTGCTCGAATCCGTTGCAATGGATGTGTTGGGACAAACGGAGCAAACTGAGCAAAGTGAACAAGTTGGGGGTTTGGAAAATGTTCTTGTGGTGCAGGAGCCGTTAAATCTTCTGGATGATTCCGGTCAGAACGCATTAACCGAATCGACACAACTCGAACCGTTACTTTTGCAACAGTTGCAATCGAATTTTTTGTTGCAATATAATTTAGTTTCGTCGTCTTTGATTCAACTAGACGATGGGACACTTGTTAATTTTAAAACGGTTAACACCGATCAAGACTTATTGCAAGAAACGGTTAAACCGCCAAGTGAACCAACAACACCAGCCGAAAAACTGAGGAATTTGGAATGTGACATTTGTCACAAGAAATACGCGTCTAAAGATGTTTTAAGGAAACATAAAAAAATCCACGGTGTGGATAAGAAGTTTAGGTGTACGAAGTGTGAAAAGGGATTTGATACGGAGGAGGATTTGGAGAAGCATAAAAGGATACATGAGGGGTATAGGCCATATTCGTGTTTCTATTGCGCTAATAGTTTTTCAAAAGAGCATAGTTTGGCAACACATTTGAAAAGGATTCACAATGTTTCGCTCAAGGATAATCTTTTATTGTGTGATCTTAAATAA
Protein Sequence
MAEGSYMDNISTFVALPVDTLENNILQKPEQFRIIKNAIIKKLSDGSVCIIDANEVNEGLPQEIEVTYLPPVDVTPVANATPDKPTVTVNKETSPKQTYKCSKCKEVFEKLVLYRKHMMWHRSIKKFKCEKCSVGYNVETNLKIHMAMHSEGKPTCPICNISFQRLASLKSHLMLHQVEELCTCEECGAEFEKEEELEKHFHSHLENTAKENNNLVCTYCSVQLDDQKSYKEHISHHVKVKKMVLSGKKSRKTHGNKEYPHVCNICSKSFSRVSLLERHSRIHSGEKPFLCQYCFRGFNQKGTLQIHYSKHTGHKPFQCTLCSAKFSQKGNLRVHVEKTHTAPLPGVKMYKCSHCTCIFKKIASLNVHITKFHSNGEDSTSISSVMNQLKELEQVAMPSSHSETVQENERVDDPNTSFVRLAESFLDGTVRRYLVKQKKVNDVRWYICNYCNKEFKKPSDLIRHTRVHTREKPFVCNKCGASFSLKTSLFSHVKTHLGNNNYFCSICMKKFSSARSVNLHLRRHSEKPQYKCLSCNKSFSSIQKAKLHYKEAHSGRSEKDSEIILKQPLVNTPDGLLPVPPPKSVHSTNSKQIQCPICCVRFSKVPNLKRHMLLHNGGKKHKCGQCMKSYYTAHALKEHVLCHSGVKNFGCKVCGKKYTTASLLKRHTLSHSTNKPYVCPYCSKNFKSVMLCRKHMNVHKKDLQITVQNISNETKNLDIDKPKLLLIPDSISNSGLLTNNQDPLETTNLQLITQPNVNEIVNPTDQQFYEITPNSIQIITNSDKDLVQDPNQIQTIFINCDNLPLGDNLYSTNTNSVLFDPMNENTFNINALNGDFSTQNTETFNDGQTNSTSTDKVSNDNLLTTNIPLYPQSELNLLFNLDTEFVSNNCDLPDININEVPDLNVEPAKENDEAKNRMTCDKCSKVFTNKKTFLKHVNSHKDRQKVAGFHQCSFCEKSFKKHSDLIRHIRTHTGEKPFACDKCEKKFSLKSTLLSHQRTHNPISHKQFNCVVCNSFFTSKSSLKVHMSVHTGDKSYKCSFCSAKFRTAAHRKSHENNYHVNPSKKKTKNKVTNLLESVAMDVLGQTEQTEQSEQVGGLENVLVVQEPLNLLDDSGQNALTESTQLEPLLLQQLQSNFLLQYNLVSSSLIQLDDGTLVNFKTVNTDQDLLQETVKPPSEPTTPAEKLRNLECDICHKKYASKDVLRKHKKIHGVDKKFRCTKCEKGFDTEEDLEKHKRIHEGYRPYSCFYCANSFSKEHSLATHLKRIHNVSLKDNLLLCDLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01481081;
90% Identity
-
80% Identity
-