Basic Information

Insect: Triatoma rubrofasciata
Gene Symbol: TRERF1
Assembly: None
Location: chr12:11118039-11190587[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.4e-05 0.0014 18.4 0.2 2 23 184 205 183 205 0.97

2 6 7.9e-08 4.8e-06 26.2 0.8 1 23 211 233 211 233 0.99

3 6 6.7e-05 0.0041 17.0 2.6 1 23 239 263 239 264 0.95

4 6 0.00032 0.019 14.9 0.8 2 23 370 391 369 391 0.97

5 6 0.00063 0.038 14.0 0.0 1 23 1216 1240 1216 1240 0.98

6 6 0.00017 0.01 15.8 0.8 1 23 1271 1293 1271 1293 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.4e-05	0.0014	18.4	0.2	2	23	184	205	183	205	0.97
2	6	7.9e-08	4.8e-06	26.2	0.8	1	23	211	233	211	233	0.99
3	6	6.7e-05	0.0041	17.0	2.6	1	23	239	263	239	264	0.95
4	6	0.00032	0.019	14.9	0.8	2	23	370	391	369	391	0.97
5	6	0.00063	0.038	14.0	0.0	1	23	1216	1240	1216	1240	0.98
6	6	0.00017	0.01	15.8	0.8	1	23	1271	1293	1271	1293	0.98

Sequence Information

Coding Sequence: ATGAAAACAATGATGCTGAAAATGGTATGGGTGACAAAAGAGTGGGATATTGTAAACGTTAGAGGAAACTGTTTGCTGAAGGGTGGCAAGGGGCAGCCAGGTACTGCGAGCAGCGCTAGTGGACATGCAGTTTACTTGTATGGACCCGCAAGTACGCTCACCACAGAGGAGGAACTGCCTGAAGGAACGTCGTTAGCTATTGCGTACTCCACACCAGATGTATTAGCTGACCCATCCATCGATGTATTACTTGGAGCATCCAACGATGCTGGGGGTTGCCGCACCGTTAGAACTGAACAGGATGTTGATTTAGGGGTTGACTTAATTGGTGGCAGTTCTGGCGCCAGTGGTTTTGAATTGTTTGATTCTCAGAGTGGTCAAGATTTAACGCTTTCACCGCAAACTTTCACCAGCTCGACAGAAGCTTTCATCAATGAAAACTCTAATATTGGCAGTACTGAAGAGGAGAAAGCGGCCGATTCTGGCAAATTAACAGTAAGAAGAGCAACCAGGCCTAAAGCACTATCTCCCAATAGGCAAGGACCACAACAATGTCAGATTTGTTCAAAGGTGTTTGGAAATGCTTCTGCGTTAGCAAAACATAAATTAACGCACAGTGATGAAAGGAAATATGTTTGCGGTATGTGCGGCAAAGCCTTCAAGAGACAGGACCATCTAAATGGTCATATGCTCACGCATCGTAACAAGAAACCTTATGAATGTAAGGCGGACGGCTGTGGAAAATCATATTGCGATGCCAGATCATTACGCCGACATACTGAGAACCATCATGCCAGTAGTTCTCCAGGTGCAGTTCCATCTAGCACTACACCATCACCAGCCGGTACCAGCGGAACTGGAGCAGATTCACCACCAACATGCATCCAATATGCACCAAGACCTACATCACCAAAGGTGAAAAGCACTAAACAAACAACACCTGTTACTACTGGTAGTGTACAGATGCAACAGAATGCTACAAAACAAGTGCAACCTGTCTCACAATTGCAGCAGTTATTGGCCACTGAACCATCACATACTTCCTTATCTTCGAACAATAAGACATCTCCCATCTCAAAAGCTGTTCCAACAAGTAGCAAACCAGTTGAATGCAACTTATGCCATCGTAAATTCAAAAATGTACCTGCATTAAACGGACATATGAGGCTACATGGTGGCTACTTTAAGAAGGAATCTGATTCTAAAAAGTGCGAAAAGAAGGAAGTTAATGGTCCGCCATTGCAGACGGCTAGTATCAGTGTGAGAGCGTTGATTGAGGAAAAGATCATACAGAAGCGGATCACCACCAGCACCGCTCAGGGCTCCCAACACCTGCCACCCACACTGTCCATTATGGAAACGCCTGTTAGAAGATTTGGGAGTAAAACTACAACAGAACCATTAGCTGTTAAAATATCTTCTTTTGTTGTACCTTCATTACCATCGGGAGGTATTAGTACAATTAATTCAGAAAAAGTAGTTATAAAAACTGAAGAAGGAATCAAAGTTGAACATATAAAGGTGGATGGAGGTTTGAAAATGAAATCATTGAAAATAGATAACAGCAAAATGGAAGGTAGTATGCAGACAGAAGTGCCGGTTAAATCAGATTCGGTTCCGGCTACTGTATCATCCATTGTTACAACACCACAACTGGCCACCAGGACTCTACATGACCATCCTATTATTTTAAAAAAAGTATCAAAACCAATAACGAAAAGAACCACATCAGATCCGGGAACAAATCATCAAGAAGTTAATGATGGAGCTCAAGCAATTCAGAACACAATACAGGGAGAAACTTATTCAATAGGTGTTTATAGCGAAGATGGTGGCTACTTTTCACCAACAATTCAGGATGACATGTTTCAACATGTTCAGTCGGTGCAAGAATCAATGCTCTTGCAGGGTGTTGATCCAGCGCAATTAGTTGATTCCATACAGGCTGCAGGTCTTCAGGATATTGGAGCTCTTGAAAATTATCACAGTCCTACTGAAAGTTTGCCAAGTCCGGAAACCTTTCCAAATCACCAAGATTTACAAAGTGTTTTGGACTCACCATTACCAGTCAGTTTAGCCGATTTTGCCTCCCTACCATCACCATCGTTTACCTATCCTACACCACCGGCTAGCCATGAAGGACAGTCACCGTCCTTTCCAAATTTAGTATCTCAAGGTAATGCTTCACCCTTATCAGCTGCTTTCTACACTTCTCCAATGTCAAGTTCGGCCGCTGTGGAAGCTGCCCTCAATGAGGTGTTGCCAGAACACGGGTACCCCTCACCGCCGCCACATTCTCCACTCTCGTCAACTCCGGTCCCATCGCCATTGTCTCTACCAGCTTCATCAACTTCTCCACTTTCCCATCCCAGTTTAACATCACAGATGATGCCAAATTCAGATGATCCATTACTATCTTCAGCGCCTAAAGATTTTGGAGCTAGAAAAAGAGTTGATATTCATGGAGTGAAAGTGGTACATCAAACCACAAATACGGTAACAGGCATGGAAGTGCCGAGTAGTGGTCAAGGCGGTGTTACTGGTATAGTTCTCGATAGAAATGGTGAACTGAAATTAATACAAACTTCATGTTTTCAATCGATTTTAAGTGGGACTGTATTCGTCAACACTAAAACAAAATTAGAACCAACTGTTCTTAGTACAGGTGAAAATGGTCCTAGAGTAGTAAAGACATTGGCTATACCCAGCAAAGCATTGCTCACTAAAACAAAACCAGGAAACGTTGAGACTTCAAAAGAGGATATTGAAGATGACGTTTTCCTGAGCCCAAACGCACCGTCCAGTCCAATAAAGAATAACCGTAAAAGACCTAGATTAGATTGTGCTACTCCGCCGAGCCGACCATATGAGAGTAGGCTGAGAGTGGCTCGCAGCCGGCATTCTTCAGAGAGGCATCTCCTCTTCACACCACCGCCTATACTCCCACCAACACGCCACGGTCAGGGACTTTACTGGCAAGCAGTAACCACTTGGCCATCCTCTACAACCTCTTTGAAGGATTGTGGCTTGGATGATGGTGGACAGGAAATTGGTAGTGCCCCAGAATGTGATACCTCACCTCATATTAATCTTGGTGCACAGTACCAAGTACAAGTACCTCCTTGGAGTCGCCCACACGAGCGAGGTAGAGATACCCCAACAAGGGAACATCTTCTGTGGGATCCAACAACTTCTAAGAACATTAGTGATACAGAAGCCGTTCCTGGAGGAGGTCGCAATAAAGAGTATGCATTACATTTATTACACCTCTGTCATGGCAAAATCCACGACGCAATGCTACGTCTAATGCAACCAACACCATTTCTACCAGTTGGTCATCCACTTCTTAGTTTTGACTATCCCGATAGTGAAAGGTGGAGTCCTAGTGAAATGGATCTATTTCAACAAGCACTTATCAAATATGATAAGGATTTCTTAGCCATTTCACAAGAGATTGGAACAAAATCAACGAAACAATGTGTACAGTTCTATTATATATGGAAGAAGGTTTGTCCAGAAGAATACAAAAGGCTGAGGTTGGTAAGACGTAGATTCAGGGAGGCTGAAAAGGAATCAGAAAGCCTAAAAGCAGAACTTCCTACAAACGATGCAGACCTAGTGTCTACGAGTTCTGAAAGCCGTTTATTCGTTTGCGAATATGCAGATTGTTCAGCTAGCTTCAACTCTAGAGCTGCATTAAACGGCCATATACGTATACATGTTGGTGGTGGAGCCGGAGGTCGTGCTTCCACTCCAGATCATAAGCGACATAATAGTCATAATTCAGCAGGGCTGGATACAATGGAGGAATTTCCCTGCAAGATCTGTGGGAAGATTTTCAATAAAGTGAAAAGTAGAAGCGCACACATGAAGTCACATCGAGCATCAGACACTGAAGCTCGTAAAAGTGCCAAAGTGGAAACTGTGACCAATAATAAAGATTGCAGTACAGAAAGTAATGCGACGGCCAGAGGAGGCCCTACCGTCTCTTCATCTTCTATTGCTCTCCATAGACATCCCTGCGACCGCTGA
Protein Sequence: MKTMMLKMVWVTKEWDIVNVRGNCLLKGGKGQPGTASSASGHAVYLYGPASTLTTEEELPEGTSLAIAYSTPDVLADPSIDVLLGASNDAGGCRTVRTEQDVDLGVDLIGGSSGASGFELFDSQSGQDLTLSPQTFTSSTEAFINENSNIGSTEEEKAADSGKLTVRRATRPKALSPNRQGPQQCQICSKVFGNASALAKHKLTHSDERKYVCGMCGKAFKRQDHLNGHMLTHRNKKPYECKADGCGKSYCDARSLRRHTENHHASSSPGAVPSSTTPSPAGTSGTGADSPPTCIQYAPRPTSPKVKSTKQTTPVTTGSVQMQQNATKQVQPVSQLQQLLATEPSHTSLSSNNKTSPISKAVPTSSKPVECNLCHRKFKNVPALNGHMRLHGGYFKKESDSKKCEKKEVNGPPLQTASISVRALIEEKIIQKRITTSTAQGSQHLPPTLSIMETPVRRFGSKTTTEPLAVKISSFVVPSLPSGGISTINSEKVVIKTEEGIKVEHIKVDGGLKMKSLKIDNSKMEGSMQTEVPVKSDSVPATVSSIVTTPQLATRTLHDHPIILKKVSKPITKRTTSDPGTNHQEVNDGAQAIQNTIQGETYSIGVYSEDGGYFSPTIQDDMFQHVQSVQESMLLQGVDPAQLVDSIQAAGLQDIGALENYHSPTESLPSPETFPNHQDLQSVLDSPLPVSLADFASLPSPSFTYPTPPASHEGQSPSFPNLVSQGNASPLSAAFYTSPMSSSAAVEAALNEVLPEHGYPSPPPHSPLSSTPVPSPLSLPASSTSPLSHPSLTSQMMPNSDDPLLSSAPKDFGARKRVDIHGVKVVHQTTNTVTGMEVPSSGQGGVTGIVLDRNGELKLIQTSCFQSILSGTVFVNTKTKLEPTVLSTGENGPRVVKTLAIPSKALLTKTKPGNVETSKEDIEDDVFLSPNAPSSPIKNNRKRPRLDCATPPSRPYESRLRVARSRHSSERHLLFTPPPILPPTRHGQGLYWQAVTTWPSSTTSLKDCGLDDGGQEIGSAPECDTSPHINLGAQYQVQVPPWSRPHERGRDTPTREHLLWDPTTSKNISDTEAVPGGGRNKEYALHLLHLCHGKIHDAMLRLMQPTPFLPVGHPLLSFDYPDSERWSPSEMDLFQQALIKYDKDFLAISQEIGTKSTKQCVQFYYIWKKVCPEEYKRLRLVRRRFREAEKESESLKAELPTNDADLVSTSSESRLFVCEYADCSASFNSRAALNGHIRIHVGGGAGGRASTPDHKRHNSHNSAGLDTMEEFPCKICGKIFNKVKSRSAHMKSHRASDTEARKSAKVETVTNNKDCSTESNATARGGPTVSSSSIALHRHPCDR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01301833;
90% Identity: iTF_01301833;
80% Identity: iTF_01479375;