Basic Information

Gene Symbol
-
Assembly
GCA_001594075.1
Location
NW:14420-21053[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.015 1.1 9.4 3.1 1 23 399 421 399 421 0.97
2 19 0.013 0.87 9.6 0.5 2 23 458 479 457 479 0.96
3 19 0.00016 0.011 15.6 1.2 1 23 545 567 545 567 0.97
4 19 0.00012 0.0082 16.0 1.1 1 23 570 592 570 592 0.98
5 19 5.3e-06 0.00037 20.2 0.5 2 23 639 661 638 661 0.96
6 19 0.013 0.92 9.6 4.0 1 23 667 689 667 689 0.96
7 19 0.0005 0.034 14.0 0.7 1 20 695 714 695 719 0.94
8 19 1e-05 0.00072 19.3 1.2 1 23 793 815 793 815 0.97
9 19 0.0003 0.021 14.7 4.7 1 23 870 892 870 892 0.97
10 19 0.00013 0.0092 15.8 0.7 1 20 897 916 897 918 0.94
11 19 0.037 2.6 8.1 0.3 2 23 929 950 929 950 0.97
12 19 2.3e-05 0.0016 18.3 0.6 2 23 989 1010 988 1010 0.97
13 19 2e-05 0.0014 18.4 1.5 1 23 1015 1037 1015 1037 0.95
14 19 0.00088 0.061 13.3 1.7 1 20 1043 1062 1043 1065 0.93
15 19 6.1e-06 0.00042 20.0 0.5 1 23 1081 1103 1081 1103 0.95
16 19 3e-07 2.1e-05 24.2 0.6 1 23 1109 1131 1109 1131 0.99
17 19 3.2e-05 0.0022 17.8 0.2 1 23 1137 1159 1137 1159 0.97
18 19 0.019 1.3 9.1 6.9 1 23 1165 1187 1165 1187 0.96
19 19 0.004 0.28 11.2 0.6 1 20 1193 1212 1193 1214 0.90

Sequence Information

Coding Sequence
ATGGACGCCGTAACGATACATACGTCGGATCCGCCGCAGGGCGAGGACGCGATCACGTCCGCTATGAAGATATGCCGCGTCTGTCTGCTCGACAATCTGATGATGCGCGATCTCTTCGCAGAGAGCGAGGTCGCGTCCCTATCCGTGAAGGCGATGAGCTTCGCCAACGTTAAGATGTTACCAGGCGACGGTTTACCGACACAGGTGTGCTGTATGTGCGTCGACAAGTTGGAATCGGCATACGAGTTTAAGTTACAAGTGGAGCAAGCTGACAACGTTCTTCGAGAAAGGCTTATGGGAGGACTAATAAAGGAcgaattatttcttaatgagGTTGAAATACACTTGGATGCTGAGAAGAATAATGGTTTGGAAGAGATGAATGACAGTGCTGATTATGAATCTACTGATACATTGCCAATTGAAACAGAAACTGACAAGAACTTTCTGAAAAGTCAATTAATGATTTTGGAAGCTGAAAAATTGGCAGAGACAGATGGTATGCAACAAGATACAGAACAAGATAACTTGCAAGAAAGCATTGAGGAAGAATTGCAGCAAGAATTAGCCAGCTCGGAAGACAATGATATGTCAGATGCTATCGATGAATCTAGGGATGAAGTATCTTCCAACAACAAGAATATTATTCGAAGTTGCACAGATGCAATTCCAACAGatgaacataattatataatgcagcAACAGTGTATTATTTTGCATACTGAACAATTCTCCTTCCATAAAAAAATGCAGGAGACCGTACCAGAATTTAAACACGATATAACGAAATACAAAGAGTCGCTATCTGAACAAAATCAAGAAAATCAATCTGAGCAAAACCAAGAGATTCAGGTTGAACAAAATCAAGAAATTCCAACTCAGCAAATCCACGAGACTCTAGCTGAGCAAACTGAAGAGACTCCAGTTCAAAATGTTCAAGCTGAACAGGAGAATCAAACTgaacaaaatcaaaataaaaaaatggaattattacagaatgaagtattaaaaaatgatactaATGAGCCAGTCATGGAACAAGAATCACCTCAGAATGAAACTAGAAGAAGTAAACGTAGATTGGTTCGTCGGACATTCACCGAGCGGGATTCCGATGAGGAGAATTACTTTGAAAATTTGAATCTCAGTTCACGATTGAAAAAAGCGCAGGCAGATAAGACAGAGAAGATCTTTTTCATGTGTTACTTGTGCGATAAACAGTTTCTTTCAAAGAGCGTCTTGAAAGAGCATATGCATTCCCATGAAGAAGTAAGGAAAACATTGTCTCTGAAGAAAACGCCGGAGAAACCGCAGAAGGTGCAGACCAGCGTTTCAGCCGTGAAAACGCCGCCATCAGGAAAGAAAGCCAACAAGTGCCCTTATTGTGGTAAAGAGTATCTGTACATAATCTCGTTTACTAAACACATTAAACAACACGAGCGAGAGCGGCAGGAAGCGAAGGAAGATCCGATGTCGTTTGAGATGTTTTATGAGGATGAGTACAGTCTAGACTTAGATAACGACAACAAATCGGATGTTGAATGTAGAAAACGAAAGAGAGGAAGTATAGTCGACGATGTCGCGAGCGACAATGATCAGGATAAGAGAAGAAAGCGTAGTCTTATTGAGGAGTTTGCGTGTAACAAATGTCTAGAAAAATTCGATACAAAGCGAGGATTGCAAAAGCATTTGCTCACGCATGTTAGCTTCAAGTGCAGCGTGTGCAACGAGGAATACGACACTCTAGAACAACTAAAAAATCATCGAACAACGCATGTAGTCGAAGGCGTACTCACTGAGCAAGACTTGGAAGAAGACATGAAGCAAATGGCCAAGTGCGAGGAGAATGATGACAACCGCAAGAACATCAAAGATGAAGAGAACAGTGAATCCGCCGAAATCACGAAGGAACTAAAGTGTCCGACGTGTTCAATAACATTTTCACGCAAGAAAGCGCTCTCCAGACACATAGAGACAATACACTCCGACACCCATTCTTACGAATGCAAGATATGCTGTCAACAATTTACACGGAAGGATTTCCTACGCAGGCATGCCGAGCAGCATGCACGAGTGAAGACTTACAAATGTACCCAATGTAACAAGACCTTCGGCAACGAGCTCACGTTGAGAAATCACCTGGTTGCCACAAATCACAAGACATTTATACAGGGACAGGAATACGATCCCAACAAGCGTATAAAGCGCGTGGCGGCAAGAGCAGCACAGAAGATCATCGACAAGATCAAGACTGAAGACGGTCTCGAAGATTACGACGATGATAACGATGATAATACCGATTACGACGTCAAATTGGACGGGCATTATCGCCGTAAGCGCGACGCTACACCAAAGAAGTACAGTTATAAGAAGGAATTTGAGTGTGCAACCTGTAATAAAAGGTACAGCTCGAAGCAAGCGTTGACGAGGCACATGGAGCAACATGTAAAGGAGGAAAAGGCAGAGAAAGCAGTGGAGAAGGCGGCGGAGAAGCAGAAGAAGACCGCTTTAGAGAAGAAGGAAGCGCACAAGAGCAACACGGGCGATAACGATGACGACGATAACAACTCCGACTTTGAAAGTGGTCTTGATTGGCCAGTAGACAGCCATGAATGCACCACGTGCAAGAAGCAATACAGTACGAAGAAGTCGTTACTGCGCCATCAACTACTACATGAAGAGCCAAATTTCGAGTGCGATATCTGCAATATCAAGTTCTATCGTAAAGACAAACTGAAGGCGCACTACGATAAATGCTCGGAAAAGAATCCTGATCAGGTGAGGAAGTGCAACATCTGCGGCGACAGTTTCGAAAACAATGAGATTCTGCGCGAGCACAGAGCCAAGCACGTCACCGAGGGTATCCTAACGGAGGAGGATCTGAGAGACACCGAGCCAAAATCCGAAGAAAAGAGACTAAATGATAAAATGACCCGGAAGAGGAGGACCGATATTGTAGGGCTCGAATGTACCGAATGCAACAAACAATATACCTCTAGGAAGGGCTTGCTGCGACACATTCAGGTTCACGAGGGCAAGAAGTACCTATGTGAAATATGCCCAAAGAAATTCTATCGGCGAGAACATCTGAAGATTCACGTGGCAAAACACAACATGATTAAACCATACAAGTGCACTCGTTGCTCCAAACGTTTCATTAAGGAGGAGCAGCTCAATAATCACCTACCTAAGCATGATCGCACTTTTAAGAAGAACAAGGAGACCGACAGCTCGAAGAGATTCCTCTGTGAGATCTGCAGCAAGAGCTTTACGCAGTCGACAACGCTGCTAGCGCATCTGCGCGCTCATAAGGGTATCAAACCGTATGTGTGCGAAGTATGCTCCAGGCCATTCACCACTAATGCCTACTTGAAGATGCATATGCGCACGCATACGCAGGAACGTCCGTACATCTGCCAATATTGTTCGCGAGCGTTTGCCCGTGCCGACACCTTGGCTAATCACCTGACGTCGCACACTGGCGAAGCCAAGTACCACTGCAAGTGCTGTCCGAAGAACTTTCGGCGATTGAAATCATTGAAGGAGCACATGTTTATTCATACGGGTCAACGACCTTACGAGTGTCCAACTTGCGACAGGAAGTTCAACAATAACGGCAGTCGCTACGCGCACAGCAAGCGCTGCAAACAGAATCTTTTGCAGAATCAGAACCGGGCGCAACAGGTGATCCAGCAGacacagcagcaacagcaacagcaacaacaacaacaacaacaacaacaacatcAACCACAGCAAGTGCAAATACAGGTGCAGCCAGAACCGCATCCAATTAGGTTGCATCAAACCACGATCGGCCAAGCACAAGTAATCAAGGCGCAAAACATCAAAACAATCGCTATAGCGAGACAAGCTGAGCCTACGGTAACCACGCAACATCAGGTTATGCAGCATCAGGAAATACTAATGCCTTTAATCCTACCACTTACCGTTACTCTTGCTGATGTAGGCGAAGAGGTGATACTACCTGAaggtacaaaaatatttaccacTTCTTAA
Protein Sequence
MDAVTIHTSDPPQGEDAITSAMKICRVCLLDNLMMRDLFAESEVASLSVKAMSFANVKMLPGDGLPTQVCCMCVDKLESAYEFKLQVEQADNVLRERLMGGLIKDELFLNEVEIHLDAEKNNGLEEMNDSADYESTDTLPIETETDKNFLKSQLMILEAEKLAETDGMQQDTEQDNLQESIEEELQQELASSEDNDMSDAIDESRDEVSSNNKNIIRSCTDAIPTDEHNYIMQQQCIILHTEQFSFHKKMQETVPEFKHDITKYKESLSEQNQENQSEQNQEIQVEQNQEIPTQQIHETLAEQTEETPVQNVQAEQENQTEQNQNKKMELLQNEVLKNDTNEPVMEQESPQNETRRSKRRLVRRTFTERDSDEENYFENLNLSSRLKKAQADKTEKIFFMCYLCDKQFLSKSVLKEHMHSHEEVRKTLSLKKTPEKPQKVQTSVSAVKTPPSGKKANKCPYCGKEYLYIISFTKHIKQHERERQEAKEDPMSFEMFYEDEYSLDLDNDNKSDVECRKRKRGSIVDDVASDNDQDKRRKRSLIEEFACNKCLEKFDTKRGLQKHLLTHVSFKCSVCNEEYDTLEQLKNHRTTHVVEGVLTEQDLEEDMKQMAKCEENDDNRKNIKDEENSESAEITKELKCPTCSITFSRKKALSRHIETIHSDTHSYECKICCQQFTRKDFLRRHAEQHARVKTYKCTQCNKTFGNELTLRNHLVATNHKTFIQGQEYDPNKRIKRVAARAAQKIIDKIKTEDGLEDYDDDNDDNTDYDVKLDGHYRRKRDATPKKYSYKKEFECATCNKRYSSKQALTRHMEQHVKEEKAEKAVEKAAEKQKKTALEKKEAHKSNTGDNDDDDNNSDFESGLDWPVDSHECTTCKKQYSTKKSLLRHQLLHEEPNFECDICNIKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDSFENNEILREHRAKHVTEGILTEEDLRDTEPKSEEKRLNDKMTRKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCEICPKKFYRREHLKIHVAKHNMIKPYKCTRCSKRFIKEEQLNNHLPKHDRTFKKNKETDSSKRFLCEICSKSFTQSTTLLAHLRAHKGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYICQYCSRAFARADTLANHLTSHTGEAKYHCKCCPKNFRRLKSLKEHMFIHTGQRPYECPTCDRKFNNNGSRYAHSKRCKQNLLQNQNRAQQVIQQTQQQQQQQQQQQQQQQHQPQQVQIQVQPEPHPIRLHQTTIGQAQVIKAQNIKTIAIARQAEPTVTTQHQVMQHQEILMPLILPLTVTLADVGEEVILPEGTKIFTTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00016834;
90% Identity
iTF_00014886;
80% Identity
-