Basic Information

Gene Symbol
-
Assembly
GCA_036026315.1
Location
JAYRCB010000656.1:223064-226543[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00014 0.014 16.4 1.5 1 23 115 138 115 138 0.96
2 13 0.012 1.2 10.3 4.6 2 23 255 277 255 277 0.91
3 13 0.00095 0.092 13.8 1.7 2 23 334 356 334 356 0.95
4 13 6.8 6.6e+02 1.7 7.6 3 23 441 462 440 462 0.95
5 13 6.4 6.2e+02 1.7 2.9 1 23 512 535 512 535 0.94
6 13 0.00038 0.037 15.0 0.1 3 23 584 605 583 605 0.95
7 13 0.35 34 5.7 2.1 3 23 632 653 630 653 0.91
8 13 0.0089 0.86 10.7 3.6 2 23 701 723 700 723 0.96
9 13 0.12 12 7.2 4.2 3 23 738 759 736 759 0.92
10 13 0.00022 0.022 15.8 0.2 2 23 804 826 804 826 0.93
11 13 0.056 5.4 8.2 1.6 1 23 912 934 912 934 0.98
12 13 0.00015 0.015 16.3 0.7 2 23 950 972 949 972 0.96
13 13 0.0052 0.5 11.5 0.4 1 23 1041 1064 1041 1064 0.98

Sequence Information

Coding Sequence
ATGACGTCCACACTATCGCGCGGTGCGATCCTGCCTGATCCTGGCGAGCTGGACAGCGACGGTTCGAGTGGAGAAGAGCGAGACGCCAGGAAGCGTCTCCATGGCGACCTGGACAGCACCGGTCCGAAGAAGCGACGGAAACAGACGACCCCGGTGAGGTTCCCGGCGTCGCTGATGACTGGTGAACGAGCGGAGTCCGAGGACGACGGCGACGAGGACGAAGCGGAAGTCGACGAGGACGTCGAGGCTGAGCGGGAAGGTAAGCAGCAGCGTCGTTCTCCCCAGGACTCGGTCACCGGTGATCATCGAGTAACGAGCAAGGACGAGAACCTGAATAACGAATTCCGCTGCCAATATTGTAGTCAATTTTTCGATAACAAGGAAACTTTGAATCAGCATATAGATAGCGAGCACTATGTACAGTCGCGAGACCAAGTGCAGGTCAAATTAGAGCCGAGCCAGGAGCAGTCCGAGAGTCCTGTCAATCTGTCGGGACTCAGTATAAAGAGTTTCGCGGCATCTTGGTTGTCGGGCCAAGTTCAAGGTCAGCCACCGGGTCAGGTTCAGGTACAGAGCGAAGACTGGACGATCGGTAGCACAGTGGCACCCGTGAGCACGATACCTAATCATCTGCAGAGTCTACCGTTTCCTGGTGCCCTGGCCCAGTACCTTCCTCTACCTGGTTTCTCGCTGCCAGACTCGAGTCAGATATCAAGACCACCCATAGGTCCGGCCCCGGTACGAATTTTCAATCCGGACGCCTACTGCGACCTCTGCAACAAGGAGTTCTGCAATAAGTACTTCCTGAAGACACACAAAGCGAACAAGCACGGCATCTACGTGGACTCGCCAGGTCAGCCAGCCACAGAATCCAATCTTGGTCCACCGGTCTACGGTGGCACGTTCACCGCTGGTAACATCAAGATGGAACAGATTCAGAGGTTAGACGTTGCAGCGGTaccaccgccgccgccgccgtgCATACCGACGCCCAGCGCCTCCTGCGACGTCTGTCAGAAGAGGTTCAAGAACGAAGAGTCCGTGAGGAAGCACAAGCAAAAGGTTCATTCGGAGAACAGTGAGCCTGGTGAGAATCAGCCGATGCAATCTTTGGACGATGACCGGGACCAGAGTTATCACAGTCTAAGCCCAGGAGCTATGGAAGCACTTTTCAAGCAGGAGTTCGGCGTGGAGCAGGAAGACACGAGCTTCATGCCGGCACCTAGACACCTGTCGCCCCAGTCGATTCAGCAAGCTAGGGATTCAGGCTTCAACGCGGATCGTCTACGTAGACTGGGTGTTATAAATCCTGACGCCTTCTGCGAGATCTGCTGCAAGGAATATTGTAACAAGTACTTCCTCAGGACGCACAAGATGAAGCGCCATGGTATCTACATCCAGGACAGCGAGAAGTCGCCCAGCAACCCTGGAGCAGCCGCCAGCTGGCACCAGGTCCAAACCAGTCCGCTCAACCTGATCGTGACCGAGACGACCGGGAACAGTTCAGAGTCCAGTGACCGACCTGGCGAGGAGCACGAGTGCAAGCCCTGCGGACTGAGATTTCAGACCAATGGATTGCATCAGGCGCATAGACAGAAGATGCACGAGATCGAAGAGCAAAGGTCACCCAAGCAGGATTACGAGGTCGAGATCACGGATCAGCGACCTGACTCCATTTCCGAAGATCTTCAGAAGCTCCAGACAATGATCCTGCAACTAAACGGTTTGGAATCTAGTCGCGGTGCACCCTGTGCTGTCTGtggaaaagaatttgaaaccCGATTGGCCCTCAGGACTCACATGACCAGCGATCACGGCGCCATCATCGAGGAGCCAACGTCACCGTGTCCGGTGATAGAGAAGTCGCCGACACCTATTGGCGGTACCGTGAACTGCACCGTCTGCGACAAGGAATGTCTCAATCACGATCTATTGAGGAAGCACGTCAGCGAGGAACATCAGAATCAGAATCAGAATTGTACACCGGCGACGACACCGCTTCCCCAGGCGGTGCCGATTCCTGTAACTACTACTCCGACGTCGGCGCCGGCGGCCCAGACCGAGCGCAAGGCGTCGGTGTCCATGACGCCAACGTCCAGCTACTGTGAGATATGCAATAAGGAGTTGTGCAACAAGTACTTCATGAAGACTCACATGCAGAGGATGCACggtattgaaattgaaaatggggCCCAGATCGGTGGCGTTATATGCAATATATGTAACAAGGAACTGTGCAGCAAGTACTTCCTCAGGGTTCACAAGCACAACACGCACGGTATCGTCGAGGAGGGCACTTCCGGTTCGACGAAGCAAGAATCTTACGAGTCCTCGAATAGCGAAGACTCGGCCTTGAAACCCGAACAGTTAGGTGACCTGAGTCACAGATACTTCACCCACTTCACCGAAGTTTGTCCGATATGCAGCAGAAGATTTAGGAGTACGAAATGGCTGAAGGCTCATCTGCTGGGAGATCATGGCAAGGCAGGGGTGGACAAATGGCGTGAACTGGAACAACAGTACCAATCGGCACCACGAGGtgggagcagcagcagcagcagcaacaataGATCGGCAGGACCCTCGAGGTCTGCGCATCAGAATTCTAGCCTAAAAATACCAAACGGCCTGGAACTGGGTCAGCACGTTAAATCTACCGATTACACCGGTCTTGGCAATCAGGTACTGTCGAACTTATTTGGTACCGGTTCCGACGATCAGCAACTCAAGACCTATAGGTGTTCCTACTGCAACTTCACGACGACGGTGCTGCCATTTTTGTTCCTTCACGAAAGGTCTCACGTGAGTCCTCAGGGCGGGACTGGCCTGGACAACGACAGGGGACTCCAATGTCCAATTTGCTCCCAGGGATTTCCACAGCCTGAACTCCTGCACCATCACCTCCTGACTCAACATCAGTTTCCTGGACTGCTCACGCAATTCCAACCGCCGACGCTGAACAACATCAGGCCTGAGATAAGCGTCGATAAGCATCAAGTTGAAACGAAGGATCAAGATCAGAAGGAGGAGCATCGGCAGAGTAGTCCTCAGACGTCATCAAGTTTGGacgttaaacaaaaaagtgaagaacCCGCGGTCCAGGTGACACCTCAGGGCGCCTATAAGTGCGCCCAGTGTGGCTACGCCACTGCCAACCTCAATAGGATCAAGAAGCACATCAGGAAGGATCACAAGACCCTCGGCGATCCTACCGATAGCGTGATAACGGAACTGAGCAAGACTCTCAAAGACGTCGCCAACAAGCACAAGGTGCCAGCCAGTTACGCGATGCCGCAGGACATGAATTCGAATCCGGACAAGACGATAATGCAGCCGTTCCTTATAGAGGAGTGCGACCTCACGACGCCCGGCGAAGAATCAAGCTCGGAGAGACGCTTCGCGCCGGCCCTCATTTATTTGCCTGTTAAATCGCGCATAAACGGCCCCTTGACTGCGTCCTTTACACTGAGTCCCGCCTGA
Protein Sequence
MTSTLSRGAILPDPGELDSDGSSGEERDARKRLHGDLDSTGPKKRRKQTTPVRFPASLMTGERAESEDDGDEDEAEVDEDVEAEREGKQQRRSPQDSVTGDHRVTSKDENLNNEFRCQYCSQFFDNKETLNQHIDSEHYVQSRDQVQVKLEPSQEQSESPVNLSGLSIKSFAASWLSGQVQGQPPGQVQVQSEDWTIGSTVAPVSTIPNHLQSLPFPGALAQYLPLPGFSLPDSSQISRPPIGPAPVRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGIYVDSPGQPATESNLGPPVYGGTFTAGNIKMEQIQRLDVAAVPPPPPPCIPTPSASCDVCQKRFKNEESVRKHKQKVHSENSEPGENQPMQSLDDDRDQSYHSLSPGAMEALFKQEFGVEQEDTSFMPAPRHLSPQSIQQARDSGFNADRLRRLGVINPDAFCEICCKEYCNKYFLRTHKMKRHGIYIQDSEKSPSNPGAAASWHQVQTSPLNLIVTETTGNSSESSDRPGEEHECKPCGLRFQTNGLHQAHRQKMHEIEEQRSPKQDYEVEITDQRPDSISEDLQKLQTMILQLNGLESSRGAPCAVCGKEFETRLALRTHMTSDHGAIIEEPTSPCPVIEKSPTPIGGTVNCTVCDKECLNHDLLRKHVSEEHQNQNQNCTPATTPLPQAVPIPVTTTPTSAPAAQTERKASVSMTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVICNICNKELCSKYFLRVHKHNTHGIVEEGTSGSTKQESYESSNSEDSALKPEQLGDLSHRYFTHFTEVCPICSRRFRSTKWLKAHLLGDHGKAGVDKWRELEQQYQSAPRGGSSSSSSNNRSAGPSRSAHQNSSLKIPNGLELGQHVKSTDYTGLGNQVLSNLFGTGSDDQQLKTYRCSYCNFTTTVLPFLFLHERSHVSPQGGTGLDNDRGLQCPICSQGFPQPELLHHHLLTQHQFPGLLTQFQPPTLNNIRPEISVDKHQVETKDQDQKEEHRQSSPQTSSSLDVKQKSEEPAVQVTPQGAYKCAQCGYATANLNRIKKHIRKDHKTLGDPTDSVITELSKTLKDVANKHKVPASYAMPQDMNSNPDKTIMQPFLIEECDLTTPGEESSSERRFAPALIYLPVKSRINGPLTASFTLSPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00253103;
90% Identity
iTF_01474985;
80% Identity
-