Basic Information

Gene Symbol
-
Assembly
GCA_900080175.1
Location
FKYK01011445.1:1125-3530[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00019 0.016 15.7 0.3 2 23 32 54 31 54 0.96
2 16 0.0021 0.17 12.4 11.8 1 23 127 150 127 150 0.98
3 16 1.8e-05 0.0015 18.9 1.6 2 23 167 188 166 188 0.96
4 16 0.0012 0.1 13.1 0.6 1 23 210 233 210 233 0.94
5 16 1.1 95 3.8 3.2 1 23 292 315 292 315 0.89
6 16 0.0057 0.47 11.0 0.1 2 20 334 352 333 354 0.93
7 16 0.0012 0.096 13.2 7.5 3 23 368 389 366 389 0.97
8 16 6.5 5.4e+02 1.4 0.2 2 21 410 429 409 432 0.70
9 16 0.0035 0.3 11.7 0.9 1 23 440 463 440 463 0.93
10 16 0.15 12 6.6 1.7 1 23 489 511 489 511 0.97
11 16 1.8e-05 0.0015 18.9 1.8 1 23 517 540 517 540 0.97
12 16 0.0011 0.094 13.2 4.3 1 23 546 568 546 568 0.98
13 16 0.00049 0.041 14.4 0.7 1 23 574 596 574 596 0.96
14 16 2.3e-05 0.0019 18.6 3.0 1 23 602 624 602 624 0.98
15 16 0.00023 0.019 15.4 2.9 1 23 630 653 630 653 0.97
16 16 0.00048 0.04 14.4 4.0 1 23 659 681 659 681 0.98

Sequence Information

Coding Sequence
ATGGAGTCGCCCTCGGCACTACCATCCTCTACAGCCTTAAAATTTCCACCCTCGTGTAAAAAAACTCGTACCatccttaaaattgaaaaatcaaaatgcaaTATTTGTGGAGTCGCTTTTACCCATTTGGACGATTTAGACTGGCACAAAGATACCATTCATAACGTATCAAGTACTACGAGCGCAGTTCGTAAAAGTTCTCGAATCCAAGCTAGGACCTCAAGTAGAACAAAAGGAGCTAGATGTCTTGAGATGATAGAAATTGACTTGGGTTTTGAGAAAGCAGATGAGAATGACGTTGTAGTGGCGGATGAAAGAGAAACCGCAGAAAATAGTGAAGAtactgcttttaaaaaattaactattgTTGAATCTGAATTTCGTTGTCATCATTGCAatcacatttgtaaaaataaatctttgatGAACAAGCATATGCGAATGTATCATTCAGACGAATCGATAAGtggtaagaaaaaaaccagCCAGACCATCCTTTCGTGTGCAATCTGCCTGAAAACTTTCACTCACAAAGCTAATCTCCGGAAACACGTGGTCACTCATAACCTTTCCCATAACGGACCTGGCGAAGAGGTAAATCGATCCGAATTAAGGTGGAAGAAAGGATATTGTTGCGATATCTGCAATCGTGGATTTAACAACCAAAGAGATATACTGGCTCATCGTGATATAGTTCACAGTACAGCGGCACCTTTTGAGTGGATGAGTTTTTACGAAAGTTTGTGTAGAGTGAGCTATTGTAATAAATGtggtaatcattttaaaaagaagggttttcaaaatcaccatTGCAAAACTGATCCTGAAGAGGTCACTGAAAAAGTACAACAATTGCTAGAATCGAATCCGTCCTTTGAATGCGATATTTGTTCGTTATGCTTTCACTGGAAGTGGATGTACAGGTCGCATCGAGAAAGTGTGCATCCCACCGTATCACCTATCGATTGGGAAACATTGATCAAGACGAATGTATCGATTTATTGTCCATTTTGCCTGAAAGCTTTCGCTGACGAAGACACGCTTTCAAAACACAGATCTTTGTGTatcgtgaattttgaaaataaagtgaaGAGGTTTGGCTGTAGCTTGTGCGATCGATCATTCTGTCGCAAATTTGATTTCCATAGACATTTAAAGACCAAACATCCCGACCCAGAGCTACCAATAGGAGTTGAGAACTACACACCGAAGACCAAAGCAAACATTCCGTGCCCATATTGTGATATCGCAATGCCAACTTGTAGAGTCATCTTGCAGCATATCAAAGATGCGCACGGCATCGAGATTGACACACCATTTGTGTGTGTCTCTTGCAATaaggttttcaaaagaaaagctACCATGGATACGCACAACCAGATATACCATCCAAAAGAAGAGAATTccgaagaaatcgaaaaaatcctCAAGGAAGCAGAAATTCTGCTAGATGGCGAGACGGCCTACCATTGTAATATCTGCAATCGTAACGTATTGAACTCGATGCAGTTTGTAGCTCACTACAGATTGCATAAAATGGAACGAAAATTCACCTGCGATTTGTGTGGCAAACAAACCCGTACCCAGCATCAGCTCAACAATCACGTTAAAATAATCCACCTGGATATTCGTAACTTCGAGTGTGACATTTGCGGTAAAAGTTTTCACTCGAAGCAGTCGTGCGAAGAACATAGACGTATTCATACTGGAGAAAGGCCATACTCGTGCGAAATCTGCGGTAAAACCTTTATCGCTATGAACGCATTGTtcactcataaaaaattccacaacgATTTCTTCGCTCATTCTTGCTCGATGtgcccaaaaaaattcaaagtacgCAGATCACTCATTAATCATGTGAGAACGCATACCGGAGAACGTCCTTATAAATGTGATCTTTGTCCAAAAACCTTCAACAACTCGTCTAGATTTTCATACCATAAAAAAGTCACACATTCAGATAATCGACCGTTCACCTGCGATCAATGTGGCAGCTGCTTCAAGGCAAATAAATTCCTAATGAGGCATATGAAACTTCACACCATTCGTACTCATATACAGTTTCGTAGACGTAATAATCCGGCTTATTTCGAAAATCACGAAACCAATGCCAAGAAGCCAACGGCGTGTGCGTCGAAAAAATCCACCCGAAACAGGAATACCAAAGCTTTTAATGGTGGTGAAACCGTTGCTACTGAAACCACTACCACAACACCAGTTTTGTATACTATTCGTACCATTCGAAAAGTTACGGGTAATGAAGTGGAAAATATACAGATCAGTAATTCGGCCACAAATGATGAGCAGACTCTGGCTGATGGTGCTAAGCCCCATTTTCTAACTGAAGCGTTCGCCGGTGATTCCGGTCAAAATGAGCGCAAGGAAGAAGCTGATGAATGGTAA
Protein Sequence
MESPSALPSSTALKFPPSCKKTRTILKIEKSKCNICGVAFTHLDDLDWHKDTIHNVSSTTSAVRKSSRIQARTSSRTKGARCLEMIEIDLGFEKADENDVVVADERETAENSEDTAFKKLTIVESEFRCHHCNHICKNKSLMNKHMRMYHSDESISGKKKTSQTILSCAICLKTFTHKANLRKHVVTHNLSHNGPGEEVNRSELRWKKGYCCDICNRGFNNQRDILAHRDIVHSTAAPFEWMSFYESLCRVSYCNKCGNHFKKKGFQNHHCKTDPEEVTEKVQQLLESNPSFECDICSLCFHWKWMYRSHRESVHPTVSPIDWETLIKTNVSIYCPFCLKAFADEDTLSKHRSLCIVNFENKVKRFGCSLCDRSFCRKFDFHRHLKTKHPDPELPIGVENYTPKTKANIPCPYCDIAMPTCRVILQHIKDAHGIEIDTPFVCVSCNKVFKRKATMDTHNQIYHPKEENSEEIEKILKEAEILLDGETAYHCNICNRNVLNSMQFVAHYRLHKMERKFTCDLCGKQTRTQHQLNNHVKIIHLDIRNFECDICGKSFHSKQSCEEHRRIHTGERPYSCEICGKTFIAMNALFTHKKFHNDFFAHSCSMCPKKFKVRRSLINHVRTHTGERPYKCDLCPKTFNNSSRFSYHKKVTHSDNRPFTCDQCGSCFKANKFLMRHMKLHTIRTHIQFRRRNNPAYFENHETNAKKPTACASKKSTRNRNTKAFNGGETVATETTTTTPVLYTIRTIRKVTGNEVENIQISNSATNDEQTLADGAKPHFLTEAFAGDSGQNERKEEADEW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01150660;
90% Identity
-
80% Identity
-