Tman017320.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Trabutina mannipara
Gene Symbol
egg
Assembly
GCA_900080175.1
Location
FKYK01015907.1:12614-17465[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.2e-11 3e-07 30.0 0.0 12 70 636 688 627 694 0.87

Sequence Information

Coding Sequence
ATGGGGTCGTTGAATGCCAACCGCAGAATTCCCGACCCCATTGAATTGCTCAGCGATgatgacgacgaagacgacatCGCAATCATCGAAGATGAACCTACTAGAAAACCGAAAAGGTCCAGAATACCTACGGAGTGTCTTAATGTGCAGTGTAAATCCGGACTGAAATATATCGAGGGTGTACCGGCTTTTATTCTAGAGTACTTCAAAGTGAAGAGAAAGAAAGGCCTTAAAGTATGCGAGGAGTGTTTTGATGAAGCTTGTACTTATTACTCGaatttacaAGAAAAGTTGGTGAACAAACAATCGATTAGTCAGGTACCATTTCAGAAGTATACACGCGTGTTGAGTATCGACTCCGATGAAGAAGATTTATCTCCTGAAGACGATGAACCTATACTAGATGAAGAAACCGTGAATTTGGTCGAAGATGATTTAggtgaaattatcaaaaacgttACAACCAAATGCAATCTTGCATTTCAAATCAACGATACTCACGATGAGTTACTCAACACTGCGATATCATTGAAAGAATCATCGGATAAACACGATATTAAATTAGAAGctcttcaaaaagaaattgacgaTATTCGTAGACTTATTTACGGCGATTTTCAGCCTCTATTTACTCATCTTCCCGAGTTGATAATTACGAAAGAAGAAGAGGAACTAAAGGAAGATAAATTACCTACTGTACAAGAAATCACCGAAGTTCCGATTAGACAAATtgcttttaaagaaaatggcACTGTTGCTAAAAAGTCTGTCGCCCGAAAACATACTTCTACCGAAAACAAAGATAGTCAAGATGTAGTAGCAGTATCGGAAGAAATAATGGAACCTCCGGCTAATTTACCTTCGGATATCGAACGAATGGTCAGAACTCCATTGAAAGCTGGCGATATAATTTACGCGATGAaacataattataaatatcCTTGGAGAAAAGGCGTTATTGTCGatatttttaccgaaaaaggatataAAGAAtatcagttgaaaattgacgTAACGAATCCGAGGAAACCTAATCCTTCGATACTGCTGCAAGGAAAATGTTTAGCTTATCCTTTTCCAGCTGCTTTCCGATTCGCAGTGGGTGCTCGTGTAATAGCAGTTTTCCTCGACGAAAGAAACACCGATAAACAAGCACAGTTTTACTCCGGGGTCATCGCTGAACCTCCGAAAGTGATGAATAAGTTCagatatttaatatttttcgatgatgGCTGCGCTCAGTACGCTCCTCACGAGAATATAAGGTTAATTTGCGAACCATCTACCAACGCTTGGGACGATGTACCTTTCGAAGGTAGAGCGTTTATCAAAAACTACCTCATACAGTATCCAGAAAGACCGATGGTCAAGTTACAGAATGCAAATGTGATTAGGGTCGAATTCCAAAGAAATTGGTATTCTGCTAAAGTATTAGAGGTGGACGCGTCCTTAGTTAAAATGCAATTCATGAACGACACTCATACAGAATGGATTTACCGAGGCTCTACTCGTTTGGAACCTTTATTCAAAGAATTTGAGGCAGCTAAACATCGTATGCAGACCGGTGATCGAGTCCGTAAAATAGGGAATAAGTCTATGAATACATCAGAAgaTAATCGCCCTTACGTGGAGTACACAAGGAACGCTGATAACGAAGAAACAGAAGGACCTATTCGAGCGGTAGCTAGAAAGAGTACGAATGCTAATAAAGATCATCGTAATCAAacagaaaaaccaaaaaaatggacTCCGGTACCAATTCCAGGAAAAGTGGAGTTTAAGAAACTTAACACATCGATTGAGCCAAAGAAATTTAAACCACATCAGTGCGGTCCATCTTGCATCGATTGGACTAATTTTAATCCGCAAAAAGTTAAAGGTATCGGCCCTTTGGCAATTCCTTCTCATTTCGGTTTTAGAAGGTTAATCATAACATTCGGCGGTAGCAAACATAATGTGATTTATAGAGCACCTTGTGGTAGGCAACTTCGTAACATGGAAGAAGTTCATTTGTATTTAAGAATTACCAAATCTCTAATGACGGTagatttcttcgattttgattacTGGGTCAGATGTCAAGCGGAATTCATCATCACAAAATGTTTTGTAGACGTACCGGATATAACTCAGCGGAAAGAGAAATGTCCTATATCTTGCGTCAACTACATCGACGATAAACTACCCGATTTCGTTGGTTATATGACCGAGCGTGAACCTAGACAAAACGTCGTACTGAATCTAGATCCAGACTTCCTGTGTGGATGCGACTGCACCGACGACTGCTTGGATAAGAAGAAATGCTCTTGTTGGCAATTGACTTACGAAGGTCAGAAACTAATACCAAATAACGTCATTGACCCGAACGTCGGTTACAGGTATCGTAGACTCAACGAGAGAGTCATCACTGGAGTTTATGAATGTAATCCGCGATGTAAGTGCTCAAAACTCAGTTGTCTGAACAGAGTTGTACAGCATCCTTTGTCACAAAAATTGCAGCTATATAAGACCGAAGCAAAAGGATGGGGTATTAGGTGCCTCAATGATATACCTCATGGTGCATTTATTTGCGTATATGCTGGCCATTTATTAACGGAACAAGAAGCTAATGAAGAAGGTAAAACTTACGGAGATGAGTATCTCGCTGAATTGGACTATATTGAAACAATCGAAAGGACAAAAGAAGATTATGAGAGTGATGTCCCTGAAGAACTACTGGAAGAAAGCGACGAAGACTCTCAAGCTGATAAATcgGCCGATTCGCGTTCTTTGCCTAAAACTAATTTACACAAGAACTCTTCCGATTCTTCATCGTCAGAAGacattttaaactttgaacgGACTATTCCTGGAGATATAAGGTCCAGACTGAGGGAACGAAAAAAACCAGCACCTCCTCCGGTTCCTGAACCTAAACCaaaagaatctaaaaaaaaagaacgttttTCGATAAGAAAGTACTGCGGCGATAACGAAGATGACGTCTTCATTATGGATGCGAAAAGTAACGGCAATATTGGTCGTTATTTAAACCATTCCTGTATGCCGAACGTATTCgttcaaaatgttttcgttGATACGCATGATCTACGATTTCCTTGGGTTGCATTTTTCGCTTTAACCCATATAACTGCTGGTTCAGAACTAACATGGGATTACAACTACGATATAGGTAGCGTAGAAGGAAAAGTGAAGTATTGTTACTGTGGCACTCAACATTGTCGAGGAAGACTGTTGTAA
Protein Sequence
MGSLNANRRIPDPIELLSDDDDEDDIAIIEDEPTRKPKRSRIPTECLNVQCKSGLKYIEGVPAFILEYFKVKRKKGLKVCEECFDEACTYYSNLQEKLVNKQSISQVPFQKYTRVLSIDSDEEDLSPEDDEPILDEETVNLVEDDLGEIIKNVTTKCNLAFQINDTHDELLNTAISLKESSDKHDIKLEALQKEIDDIRRLIYGDFQPLFTHLPELIITKEEEELKEDKLPTVQEITEVPIRQIAFKENGTVAKKSVARKHTSTENKDSQDVVAVSEEIMEPPANLPSDIERMVRTPLKAGDIIYAMKHNYKYPWRKGVIVDIFTEKGYKEYQLKIDVTNPRKPNPSILLQGKCLAYPFPAAFRFAVGARVIAVFLDERNTDKQAQFYSGVIAEPPKVMNKFRYLIFFDDGCAQYAPHENIRLICEPSTNAWDDVPFEGRAFIKNYLIQYPERPMVKLQNANVIRVEFQRNWYSAKVLEVDASLVKMQFMNDTHTEWIYRGSTRLEPLFKEFEAAKHRMQTGDRVRKIGNKSMNTSEDNRPYVEYTRNADNEETEGPIRAVARKSTNANKDHRNQTEKPKKWTPVPIPGKVEFKKLNTSIEPKKFKPHQCGPSCIDWTNFNPQKVKGIGPLAIPSHFGFRRLIITFGGSKHNVIYRAPCGRQLRNMEEVHLYLRITKSLMTVDFFDFDYWVRCQAEFIITKCFVDVPDITQRKEKCPISCVNYIDDKLPDFVGYMTEREPRQNVVLNLDPDFLCGCDCTDDCLDKKKCSCWQLTYEGQKLIPNNVIDPNVGYRYRRLNERVITGVYECNPRCKCSKLSCLNRVVQHPLSQKLQLYKTEAKGWGIRCLNDIPHGAFICVYAGHLLTEQEANEEGKTYGDEYLAELDYIETIERTKEDYESDVPEELLEESDEDSQADKSADSRSLPKTNLHKNSSDSSSSEDILNFERTIPGDIRSRLRERKKPAPPPVPEPKPKESKKKERFSIRKYCGDNEDDVFIMDAKSNGNIGRYLNHSCMPNVFVQNVFVDTHDLRFPWVAFFALTHITAGSELTWDYNYDIGSVEGKVKYCYCGTQHCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00194311; iTF_01150347; iTF_01490972; iTF_01263371; iTF_00725519;
90% Identity
-
80% Identity
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