Basic Information

Insect: Toxorhynchites rutilus
Gene Symbol: egg_1
Assembly: GCA_029784135.1
Location: CM056649.1:155479392-155495114[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.5e-15 5.1e-11 43.7 0.1 5 74 1093 1156 1090 1159 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.5e-15	5.1e-11	43.7	0.1	5	74	1093	1156	1090	1159	0.92

Sequence Information

Coding Sequence: ATGGGGGATTCCAGTGCCGAGACCAGTGTACAATCACATAAACCGAAAGTACCGATTACGATCGATATTTTATCTGACGATGAAGGAGGACCATCGAATCAAGAATCGACCACGATCGACAAGGGAGACTCAGCTTCTGAAACTAAAGATGAAAAAGCAGAAGAAAAGTCAGTAGTTGCAGTTGAAACTGAGGAAGCAGCTAGTGCTGTTGAGGAAAATAAAGAGCCGGTAAAAACATTGCCGGATGATTCGAAGAGCTCAGAATGTGAAAATTCAgctaagaaaaaaagaaaaacggaGATCATCCGAATAGATGACGACGAAGATGAAAAGAAGAACGCGAAGGACCAAGCCGGTGTGAAAATGCCTGATAGTGAGCCGTCAAAACATGTGAAAGTAATAGaagaatctgttgaaaaatcttcagaGCAAGCAGATAGCACAGAATTCTTAGAGGTTGTTCGTGAGGAGACAAACAGCAAGAAAATTCCGAGCAACAGCGTTTCACCGGTTGATTCTACTGAAGCAACGCAACCGACTGACCCAGTGAATTCCGGCAGCGTAGAGGAAGCTCCAGAGGCTGAACAGAAAACAGACGACAAGGAAAATGAAAGCAAACAAAATGCAGAGGAAAATCCTAACGATGATATAATTATGTTGGATGAGAATTATGATAACGTGGAAAAGAAGAAATCGAAAACAAATGCAAACCAAGATAATATGGACTGTGAAAATGAGAATGAAGATAATTCGAGCAAACAACAGGCTTCTATGGATGGAGATAAACTTCCAGGCGATCGGAATAAACCTGATTCGTCGCACTCGGATAATACTCCACccacagaagaaaaacgaaaactaGCAGAAACCaataatgaagaaaacaaagacaAAAATGAAGACGTCGATGTAGAATTAGACCATAAACCTACGAATGCAGTAGAAAAAGAAACTGGGGATAAAAATAATGATGATATCATGGATTTAGATTCTGATTCGACAAACGCAGAACCAACGGACAAACAAGCTCAAAGCTCTCAAAATTCATTAGACAAGCAAAGTGAAGCAGACATGACAGATGAAGCATGTTCAAAGAGTGAAAACAATACTGAACAGACGAAACCGGATTTGGACAAACCTAAAGTTTTAGAAGAAGATAACAAACCACAATCATCCGATCAGACCCCAGCGAAGAAGCAAATTGTGCTTGACGAAAAATTGGGAACATTCGCAGAAAAAGATGCCCTACCGGAGGAAAAAGTTCCCGTTCTAATAACGGGTGACTCAGATGAAGATGTTGTCATGATTGAGGACGATGATCAGAAAGACCCGAAGGGTGCGAATCTGTTACCTAAAAAAACTGAACCGACAAGCAGCACTGCATCTAAAGGGCCGATACCAAAGGTGGACGCTAAGCAGGAAAAACCAAGTCGAAAAGTGCTGAGTATTGACTGCGTCAATCCCGAATGTAAAAAGGATTGTAAAGAAACTGCACCAGCACCCGCCTTTGTGCTCAATTTCTTCGGTGtgccaaaaaaatccaaacgacaACGCGTTTGTATGGTTTGTTATGACGATGTCCTGCTCAAATACTCTaaTCTTTGTGGCATGATAATGGATCAGCAACCGTTATTGTTCTGCGAGCTCCCTCAGAAAAATGAACTCGTCGAGATATCCGATAGCagcgaagaagaggaagacgaAGAAATTAAAAAGGAAGTGGAAAAGCCACTTGAAGCCGATATTATTTCACTGGTAGAATCGGAACTGAACGACATTTTGACCGACACATTCGAGAAAATTAATCTCAACCAACAAATAGATTGGACGGAACAAATTATGACACAAAGGATTGCCTACAATACGAagctttccaacgaaatcaacaACGAGTTGAGCGAATTGCAGCGCAAGGTCGACCGAATCCATTTGCAACTTTACTCTAAATCTCGGCCGAGATATCAGGATTTGCCACCGTGTAACATTTATCACGAAGTGGATCTAGTGAATAAGAGTCAACTATCATCTTCGTGTCAAACACCCCAAAGAACGCAACAGCAAGCGAAACAAACACTCCAAACTTCAACATCAGCGCAAAGTGTGGTGTCCTCTACTCCCCAAGCAGGAATTGTGGCGAAAAAAGAAGATTTATTCATCAGGCCAGCGATTGTCGTTGGTCAGTTCTATTTTGCGGTTAAACACAAACTTCTCAGCAATTGGGCTGAATGCCAAATAGTTGAAGCGGTGACCGTATCAGACAAATGTGTATACAAGGTTAACTTCCTGTTCAATCAAGGCGCCAACACCACTCCGGTCAAAGTTGTTCCAGCTAGATATCTTGCCTATCGGCACTCTTTCAATGTGAAACTACCATTGGGCACTCGTGTCATTGCACGTTTCGATGCAGGTACTACACAACCAACGCAAACTAAGCAACCGTCACAAACAAAGACATGCTCGTTCTATCCTGGTATCATAGCCGAATCGTTCGGCAAGTATAACCGTCAGCGCTATTTGATTTTCTTTGACGACGGATACGCACAGTACGTAGGTCATGGCGATGTGCGAGTCGTTTGCGAGGAATCAAAAGAAGTGTGGATGGATATTCATCCACATTCACAGGAGTTCATTAAGAACTATCTGGCGAACTTCCGCTCCCAGCGACCTATGGTGCAGGTGAAAGTTGGTCAACGAATAATCACCGAATGGAAAGGCAAGTGGATTTACGCCAAAGTGGTAGATATCGATGCTAGTTTGGTGCAGTTGCATTTCCCCGACGACAACCGCTACGAATGGATATATCGAGGTTCTACTCGACTCGGCCCGTTGTACCAGGAGAAGGCCCTCAGTATGGGCAAAATGAGCAACAACAAATTCtccaaatttcaaaaacgaaatgaGCCCTCTATTGAGTACATCACtatcgatgacgatgatgatgctcAGAATAAACAGCAGGATGTGAAGAAGCCAACCCCCCAGGAGCAGGCATTGCAAAGCTACAATCAACAAAACAAATCCATCTCGCCGTCAGACGCTGTTGCAAATCGTTCCGTTGCCAAGAAGAGTACTACTATCGTTCGTACTGGTTCCACGTCCAGCTCCCAACCATCGGCGGTTTTCATGAACAGCTCCACAATTTACTGCGAAGATGACCGACCCAAGGGAAAAATCGTGTATTATACCGCCAAGAAACATCTGCCTCCACTGAAATACAAACAGCACGAGTGTAACCCGAACTGTCTGTTCAAAATTACGCACAATCTCAAATCGTATAGCCCTTTGGCAAAACCGCTGCTCTCGGGTTGGGAGCGGCAACTTTGCAAAATGAAATACAAGAAAGTATTTGTCGTGTACCGTGCTCCATGTGGCAGGCGGTTGAGAAACATGTACGAGCTGCACAAGTACATCCGGATGACCAAAGCCACGTTGAATGTGGACAACTTTGACTTCGATCCTATGGTCCATTGCCTGGCGGAATACGTGATCGAGAATCACATCTACCACAATCCGGATATCTCGGACGGGCGCGAGTTCATGGCGGTCCCGTGTGTCAACTACTTCGACGATTCGAAACCTCCTCCGTGCATATACTCTACGGAGCGGATCCCATCGGAAGGCGTGAAACTGAATCtggatacagattttctgtgcGGTTGCGATTGTGAAGACGACTGCCTCGATAAAACTCGTTGCCAGTGCTGGCAGCTTACGATCGCCGGTGCTAAATTCGGTAATCCAACCACTTCGATCGACAACATCGGCTATGTGTACAAGCGGCTGCAGGAAACGGTTGTCACCGGAATCTATGAGTGCAATGCACGATGCAAATGCAACAGCAGCTGTTTGAATCGCGTCGTTCAACACCCACTGCAAACGAAGCTGCAGGTGTTCAAAACGAGCAACCGTGGCTGGGGCATTCGCTGTTTGAACGACGTATCGAAGGGAAGCTTCATCTGCATCTACTCGGGACATTTACTGACGGAGGAAGCTGGAAACATGATCTGTCAGATGAACGCGAATAAGGCAGGGGACGAATATTTCGCCGATTTGGATTACATCGAAACGGTGGAGCAGTTGAAGGAAGGGTACGAGACAGATGTGGTTGAGTCGGATAGTGAACTCGATAGCGACGAGGCGGAATACGACGCAAAACGTGATACCGACGCATCGGATGATGACTTTACTACGAGCTGCAACCCTTCCAAGGCTGCGGTAAAAACTAGATCTCAAGTTAGAAGAGATAGCACTAAAAAGACAGATCCCAAGagACAAAGTAAAAAGAAGGAAGATAATGGATATGGTTCTGATGATGAACGCGAAATGGTGAACTTAGTGCCCAATTCGGACATGACCAAAGGAGATGAATCCAGCCCTTCGATAAAATATCGCTCGGTACGTAAACTGTTTGGGAAACACGAGCAGATATACATCATGgatgccaaaaagtctggaaaTCTTGGTCGATACTTTAATcaTTCCTGCAATCCGAACCTATTTGTGCAGAACGTTTTCGTCGATACGCATGATCTTCGATTCCCGTGGGTAGCATTCTTTGCGTTGTCCAATGTTAGAGCAGGCTCAGAGCTAACATGGAATTATAACTACGACGTGGGATCCGTACCAGGAAAAGTGTTGTATTGCCAGTGCGGCGCTGAAAACTGCCGTCAACGATTACTGTAA
Protein Sequence: MGDSSAETSVQSHKPKVPITIDILSDDEGGPSNQESTTIDKGDSASETKDEKAEEKSVVAVETEEAASAVEENKEPVKTLPDDSKSSECENSAKKKRKTEIIRIDDDEDEKKNAKDQAGVKMPDSEPSKHVKVIEESVEKSSEQADSTEFLEVVREETNSKKIPSNSVSPVDSTEATQPTDPVNSGSVEEAPEAEQKTDDKENESKQNAEENPNDDIIMLDENYDNVEKKKSKTNANQDNMDCENENEDNSSKQQASMDGDKLPGDRNKPDSSHSDNTPPTEEKRKLAETNNEENKDKNEDVDVELDHKPTNAVEKETGDKNNDDIMDLDSDSTNAEPTDKQAQSSQNSLDKQSEADMTDEACSKSENNTEQTKPDLDKPKVLEEDNKPQSSDQTPAKKQIVLDEKLGTFAEKDALPEEKVPVLITGDSDEDVVMIEDDDQKDPKGANLLPKKTEPTSSTASKGPIPKVDAKQEKPSRKVLSIDCVNPECKKDCKETAPAPAFVLNFFGVPKKSKRQRVCMVCYDDVLLKYSNLCGMIMDQQPLLFCELPQKNELVEISDSSEEEEDEEIKKEVEKPLEADIISLVESELNDILTDTFEKINLNQQIDWTEQIMTQRIAYNTKLSNEINNELSELQRKVDRIHLQLYSKSRPRYQDLPPCNIYHEVDLVNKSQLSSSCQTPQRTQQQAKQTLQTSTSAQSVVSSTPQAGIVAKKEDLFIRPAIVVGQFYFAVKHKLLSNWAECQIVEAVTVSDKCVYKVNFLFNQGANTTPVKVVPARYLAYRHSFNVKLPLGTRVIARFDAGTTQPTQTKQPSQTKTCSFYPGIIAESFGKYNRQRYLIFFDDGYAQYVGHGDVRVVCEESKEVWMDIHPHSQEFIKNYLANFRSQRPMVQVKVGQRIITEWKGKWIYAKVVDIDASLVQLHFPDDNRYEWIYRGSTRLGPLYQEKALSMGKMSNNKFSKFQKRNEPSIEYITIDDDDDAQNKQQDVKKPTPQEQALQSYNQQNKSISPSDAVANRSVAKKSTTIVRTGSTSSSQPSAVFMNSSTIYCEDDRPKGKIVYYTAKKHLPPLKYKQHECNPNCLFKITHNLKSYSPLAKPLLSGWERQLCKMKYKKVFVVYRAPCGRRLRNMYELHKYIRMTKATLNVDNFDFDPMVHCLAEYVIENHIYHNPDISDGREFMAVPCVNYFDDSKPPPCIYSTERIPSEGVKLNLDTDFLCGCDCEDDCLDKTRCQCWQLTIAGAKFGNPTTSIDNIGYVYKRLQETVVTGIYECNARCKCNSSCLNRVVQHPLQTKLQVFKTSNRGWGIRCLNDVSKGSFICIYSGHLLTEEAGNMICQMNANKAGDEYFADLDYIETVEQLKEGYETDVVESDSELDSDEAEYDAKRDTDASDDDFTTSCNPSKAAVKTRSQVRRDSTKKTDPKRQSKKKEDNGYGSDDEREMVNLVPNSDMTKGDESSPSIKYRSVRKLFGKHEQIYIMDAKKSGNLGRYFNHSCNPNLFVQNVFVDTHDLRFPWVAFFALSNVRAGSELTWNYNYDVGSVPGKVLYCQCGAENCRQRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -