Tmul018895.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Toxonevra muliebris
Gene Symbol
ZNF131
Assembly
GCA_963691655.1
Location
OY829328.1:71807014-71816342[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00063 0.05 14.7 1.2 1 23 147 169 147 169 0.98
2 16 0.13 10 7.4 5.5 1 23 175 198 175 198 0.93
3 16 0.00075 0.06 14.5 0.9 2 23 445 466 444 466 0.97
4 16 4.7 3.8e+02 2.5 4.1 1 23 472 495 472 495 0.94
5 16 0.15 12 7.2 1.3 1 23 520 543 520 543 0.96
6 16 0.0065 0.52 11.5 4.9 3 23 589 609 587 609 0.97
7 16 0.015 1.2 10.4 3.7 3 23 804 824 803 824 0.92
8 16 0.047 3.8 8.8 0.6 1 23 830 853 830 853 0.93
9 16 0.42 33 5.8 0.1 2 23 890 912 889 912 0.95
10 16 0.15 12 7.2 0.4 1 23 926 949 926 949 0.96
11 16 0.12 9.6 7.5 1.4 1 23 1048 1070 1048 1070 0.97
12 16 0.0024 0.19 12.9 3.5 1 23 1081 1103 1081 1103 0.98
13 16 1.3e-05 0.001 20.0 0.5 1 23 1108 1130 1108 1130 0.98
14 16 0.00044 0.035 15.2 8.6 1 23 1136 1159 1136 1159 0.95
15 16 0.0061 0.48 11.6 0.5 1 20 1164 1185 1164 1188 0.92
16 16 1.8e-05 0.0015 19.5 1.8 1 23 1194 1217 1194 1217 0.98

Sequence Information

Coding Sequence
atggacgaAAGTTATGGCGGAACGATGGATTACAAGCTTGTCTGTAGAACGTGCCTTACTGCAGATGCAGAATTCTATAAATTAAGTGCACCCATAATATGTGATGAAGATGATGAGGAAAAGACTAGTTTTCAAGAATGTTTACGCTATTGTACGCATCTAGAAGATGTATCACAATATCCAATTTACATTTGTACTGAATGTAGCACAGCATTACAAGTGTCATATAACTTTATACGAAATGCTGTGGAGGCACATGAAATTCTGCGCCAAAAATTGTGCCCAGCACAGCAGCGAAATAATGGTGGATTACACATGGGAACGTCGTCGTCATCGATAGGTGGTGATGATGAAAGTGGGTGTGGCGGCGCCGTAGGTAGAAGGGGAGAGGGAAGAACTGATATTGCATCGggttCTGATATGGATAAAAAAATGCGATTCCGCTGTAAAATATGTAATGaaaaagtagaaacaaaaaaatcgttaaaagaACATGTTAAATTACATTTGGATATCATCTCATACTGCTGCAAAATGTGTAATTATGAAAGTAAGAAACGTAGTCATCTAAGCAATCATTATTCGGCTGCACATGGTATGGAACCTACACGGGATCAACTGAAACCAAAAACTTTAGTACATCAACCGAAAATCGAAGAAGATGCCAGagtaaaaaatgaaagagataatgacaaatttgaaacattttcccAAAATGACGACGAAATTTATCTGCAAATGGAGAAAATACACAACAGCGCAAATAACCCTGATGCTGATTATGATGACGACGAACTGTTAAAAGAGCAACGACAACAACTTTTTGAATTAGAGCATCAATTAGAGTTagaacagcagcaaaaacagcaacaagtgCTACAGCAAGAGCAGCAACTAGATGAGGATATTGCTATGGCAAATGTGATACCCACTGTcataaataatgataatatacAAGATTTTCGAAATGATTTTACTGTAGCGGCCAACGAATTAAGTATTGGTAATGAATTCATTGTGATGGCAGATGGTAGCGTTGAAGAAGTCATGGAAAAtgGTGTAGTAATTGAATACATTAATGCTGCTGATGATGGTGTTACTCTGGAAAATGGTTTAGTTTTAAATGATATCGTGCAAGTTGAACAACATACAACTAGTAATCCTGATGACGTTGTTTTAGACAACAATGGTACAAACGCCATGAATATGGATGTTGATGACATGATAATTGAAGAAAATGTTATGGCTGAAGATATGCCCAGCATTGAAGATGACATTCCACAATCTATTATCACTGTTAGTGGAGTGACGGCgggaaatgaaaagaaaatcaaatgcaaaatatgcgCTGACAATTTTAGTACTCAAGAGAAATTAAAAACGCACATGTTAACACATAATGAGATACCACATTTTTTCTGTGATCAATGCACATTTTATACGTtctttaaaatcgatttaacgCAACATTATAAAACCAAGCATAAATTACAACCAACTTTTAAACAATTACAAccgaaaaataaagttaaaaccGAAGTGGATACACGTCATATATACACATGTGATTTATGTCTATTTGAGACATATGTAAAAGTCAATTTACGTCGTCATTATTTGAGTAAACATCAAGTTGAGGCAACAGATGTACAATTACGTCCAACACTAGATGAAACCGATCTTGATGCCCTACCAATTGTACGCACTccgaaaaagaaacaatcagCTAAACCACCTAAACCTGATTATCCGCATGGTATGAATtgtaaaaagtgttttaaaacCTTCTATTAtcgtaataaattaaaagagcaCTATAAGCGTCATAATCTTGAATTGGATGTAGATACATTAGAATCGAATAGTTTTGGAATGCAAACCATTTCACAACATCAGCCGCAGCACCAGCGCGAGCAACACCAACAccatcaacaacaaacaacagccACAATAAAATACAATGCACAAGAAGATTATATTTTTGCAGAACAGCAAAATGAACATCAACAAACCAGCAATATGCTCGATAatacaagaacaacaaatacTCCCGCATATACCACTACTACCAATTCTATTATTAATAAGCCACttacaacaccaacaacaataacgacaacCACTAGCACCGGTTATAGCGCATTACCCTCAGATGCGATACCACAAATTGTTGAAACGGATACTGCTATTGATAAtgatattgattttgattttaatgatgCTCTCTTTGAGGAttttgaagatgatgatgatgaaaatgacaatgatgatgatgataatgaacaATTGCAAGATTTACTCTTGACCAGCGAAGATGATTTTGAAGATGTACTcgaagaacaacagcaacagcaacaaaaccatGACACCAATAATGATAATATATTAAATAGTATGCCACAACCATATTGCATACAttgcaataagaaatttttcagtCAATATCAATTTGAGAATCATATGTTTGTGCATCGtgGGCTTGCGCCATATCGTTGTGAAAtgtgtacaaatttatataatacaAAACGTGCTCTGATAAGACATTACACTGCTGTGCATAAAAGAGTACCTACTAGAGATATGATACAGGCTAAGGGAGATAAAGtttcaGTGGACAGAACGCCTATCGAGCATTTAAATCTACAAGAACAAAAAGCAATCACGTTAATGTGTGCAAAATGTCCTTATGAATCAAcagaattattaaatttacaaatacattTAAGTACAAGCCATGGGATTTCAGATGAAAGTTTCATTTTACAAAAATTATCTTTCGAATGTCCCAGATGCATACGCTCCTATGTATCAAAATTACGCCTTATAAGACACTTGGAACGTAGTCATTCTGTAGCTACAATTATACAACAGCAATCACAACTGGCTTCAGTCGAGAgttcatcatcaacatcaacaacaccTGCGTCAACTGCCTCAAATTCTAGATGTGgCATAGTAGAGCTAACCCCAATTGCATCAACATCATCAATAGATATCAATGATGAAATTACTGTAAAAGAGGAAATAAACACCATAACAGCTACCATTAAAGCAGAAACGGCAACAGAATCAACATTAATACCAACATCAAGCACAACCACATCAATAGAATCAGAAACAAAACTAATACAAAAATCTCATTATAATTGCAAAGCATGTGATTTTGTTTGCAGTACCATTGAACTATTAAATGAGCATAGTAAATCACATCCCAGTGATGATATACgcacaaatttcaattttgaatgcAGCATTTGTTCGTGTAAGTATAAAACAATTGAAGCGTTAAAATATCATATGAAAAGGCATATAGCGCGAAAATATCGTTGCAAACAATGCCCGAAATCATATATAAATCGTGGTGAATTGAATAATCATCTATTGCTCCATACCGGCGAGATGCCACATAAATGTGATATGTGCAATAAGAAATTTCGTTATTCTCATCATTTGAAGCGACATCGTGATGTTTTGCATTATGGAAAACGTTTTCGTTGCCCGACTGATGGTTGCGAAAGATTTTTTACAACGCAAGCGCAAATGAAAATACACACATGGACTCATAATGGAAATGTTCCCTATAAATGTAAATACTGTGATCGTGATTTTATAAAACGTGAATCTCTTCGTCAACATGCCCGCAAAGTGCATAATGTAAATTTAACTGAAGAGGAGATAGCTGAGATTTTTCGTAACGTTGTTGGCCATACAAATCCTCATGATTTCACTGTATCCGTCTCGAATGGAAAAATGGTGCGTCGCAGTGAAGTTGAAGCTGCCGAAGCAGAATcggaaatatttttgcaaaatagttGCAGTAATCTTccaaatgatgatgatgaaaatttagattaa
Protein Sequence
MDESYGGTMDYKLVCRTCLTADAEFYKLSAPIICDEDDEEKTSFQECLRYCTHLEDVSQYPIYICTECSTALQVSYNFIRNAVEAHEILRQKLCPAQQRNNGGLHMGTSSSSIGGDDESGCGGAVGRRGEGRTDIASGSDMDKKMRFRCKICNEKVETKKSLKEHVKLHLDIISYCCKMCNYESKKRSHLSNHYSAAHGMEPTRDQLKPKTLVHQPKIEEDARVKNERDNDKFETFSQNDDEIYLQMEKIHNSANNPDADYDDDELLKEQRQQLFELEHQLELEQQQKQQQVLQQEQQLDEDIAMANVIPTVINNDNIQDFRNDFTVAANELSIGNEFIVMADGSVEEVMENGVVIEYINAADDGVTLENGLVLNDIVQVEQHTTSNPDDVVLDNNGTNAMNMDVDDMIIEENVMAEDMPSIEDDIPQSIITVSGVTAGNEKKIKCKICADNFSTQEKLKTHMLTHNEIPHFFCDQCTFYTFFKIDLTQHYKTKHKLQPTFKQLQPKNKVKTEVDTRHIYTCDLCLFETYVKVNLRRHYLSKHQVEATDVQLRPTLDETDLDALPIVRTPKKKQSAKPPKPDYPHGMNCKKCFKTFYYRNKLKEHYKRHNLELDVDTLESNSFGMQTISQHQPQHQREQHQHHQQQTTATIKYNAQEDYIFAEQQNEHQQTSNMLDNTRTTNTPAYTTTTNSIINKPLTTPTTITTTTSTGYSALPSDAIPQIVETDTAIDNDIDFDFNDALFEDFEDDDDENDNDDDDNEQLQDLLLTSEDDFEDVLEEQQQQQQNHDTNNDNILNSMPQPYCIHCNKKFFSQYQFENHMFVHRGLAPYRCEMCTNLYNTKRALIRHYTAVHKRVPTRDMIQAKGDKVSVDRTPIEHLNLQEQKAITLMCAKCPYESTELLNLQIHLSTSHGISDESFILQKLSFECPRCIRSYVSKLRLIRHLERSHSVATIIQQQSQLASVESSSSTSTTPASTASNSRCGIVELTPIASTSSIDINDEITVKEEINTITATIKAETATESTLIPTSSTTTSIESETKLIQKSHYNCKACDFVCSTIELLNEHSKSHPSDDIRTNFNFECSICSCKYKTIEALKYHMKRHIARKYRCKQCPKSYINRGELNNHLLLHTGEMPHKCDMCNKKFRYSHHLKRHRDVLHYGKRFRCPTDGCERFFTTQAQMKIHTWTHNGNVPYKCKYCDRDFIKRESLRQHARKVHNVNLTEEEIAEIFRNVVGHTNPHDFTVSVSNGKMVRRSEVEAAEAESEIFLQNSCSNLPNDDDENLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01133177;
90% Identity
-
80% Identity
-