Basic Information

Insect: Toxonevra muliebris
Gene Symbol: zfh1
Assembly: GCA_963691655.1
Location: OY829327.1:35062348-35068327[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0001 0.008 17.2 0.8 1 23 202 224 202 224 0.95

2 15 0.0011 0.09 13.9 0.4 3 23 232 252 231 252 0.98

3 15 0.00079 0.063 14.4 0.1 1 23 408 430 408 430 0.97

4 15 0.0022 0.18 13.0 1.0 1 23 436 458 436 459 0.96

5 15 0.00018 0.014 16.4 3.2 1 23 488 510 488 511 0.95

6 15 0.013 1 10.6 0.3 1 23 534 556 534 556 0.94

7 15 0.014 1.1 10.5 2.1 1 23 562 585 562 585 0.97

8 15 0.4 32 5.9 0.3 5 19 596 610 593 611 0.91

9 15 0.00024 0.019 16.0 5.6 1 23 620 642 620 642 0.97

10 15 0.092 7.3 7.9 1.3 3 23 649 669 647 669 0.96

11 15 1.4e-05 0.0011 19.9 1.0 1 23 678 700 678 700 0.98

12 15 0.007 0.56 11.4 0.2 3 23 708 728 706 728 0.97

13 15 0.00022 0.018 16.1 0.3 1 23 734 756 734 757 0.95

14 15 0.084 6.7 8.0 0.1 1 23 767 789 767 789 0.96

15 15 0.068 5.4 8.3 0.0 1 20 1367 1386 1367 1389 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0001	0.008	17.2	0.8	1	23	202	224	202	224	0.95
2	15	0.0011	0.09	13.9	0.4	3	23	232	252	231	252	0.98
3	15	0.00079	0.063	14.4	0.1	1	23	408	430	408	430	0.97
4	15	0.0022	0.18	13.0	1.0	1	23	436	458	436	459	0.96
5	15	0.00018	0.014	16.4	3.2	1	23	488	510	488	511	0.95
6	15	0.013	1	10.6	0.3	1	23	534	556	534	556	0.94
7	15	0.014	1.1	10.5	2.1	1	23	562	585	562	585	0.97
8	15	0.4	32	5.9	0.3	5	19	596	610	593	611	0.91
9	15	0.00024	0.019	16.0	5.6	1	23	620	642	620	642	0.97
10	15	0.092	7.3	7.9	1.3	3	23	649	669	647	669	0.96
11	15	1.4e-05	0.0011	19.9	1.0	1	23	678	700	678	700	0.98
12	15	0.007	0.56	11.4	0.2	3	23	708	728	706	728	0.97
13	15	0.00022	0.018	16.1	0.3	1	23	734	756	734	757	0.95
14	15	0.084	6.7	8.0	0.1	1	23	767	789	767	789	0.96
15	15	0.068	5.4	8.3	0.0	1	20	1367	1386	1367	1389	0.93

Sequence Information

Coding Sequence: ATGGATGGGCAATCGTATGGAATTCAATGGATACAGCATGACATGAAAACAGCTGGTCAAATGATTATAGATGCACAGCCACCGCATGAGGAAGATATTTTGGCGAGTAGTGGTGACACCGATGATGGTGTGCAATATTTGGTAGATGATGATGAGCACGATGGAAATGTACATGTGCGGGCCACGGCGGCCGACATTGATCAAATTGCCGCTGAGAATCTTATATTTATGGCAAGAGATGGTCAAATGGTCACCGAGATAATAGGCACTGATGAAAACGGTGCTGTTGTGGTATCGGCCAGCGATGGTACCACAATAGATTGTGAAGCTGTGATGCAACAAGCTGCAGATATGTCATCGAATGACGCGACCGAACAACATGATGATGCGGGAGGTGGTGGTTGCGAGTATTCAGAAGAGTATACGGAGACTACACCCCAAATGGTTACAGAAGAAGTGATTACAGATGATTGGGTGCAGCATCAGGGTGAAGAACGtGTGGAAATTCCAGCGGAGCAAATAATTGGTTCAAATTCACACGTTCTTCTGGATATTGAAGTACCACTCCCCACTATGCAGGATGAGTACACTGCGCTGCGTCCTTATCCTTGCGACTTTTGCAGTCGTCGCTTTCGTAAGAAGGCTAGTCTCAACAATCACATGGTGGCACATCAACATGATCGTCCAAATCTTTGTAAATTATGTGGTGCGCGCTTTTTTCGACGTGGCGATTTGATAAATCATTTGAAGGCGCATGCCGAGGCACCCGAAGTTGATGGAGATTTTATAAGTTTTGTGGAACGAGAACATCATCAACAGCGTCATCATCATGCCAACGATCATTACTACGATCAAGATTGGAGCGTTAATACTGATGCAATTACAGGTGGTTATCATCATCCCGGTAAATCTAGTCGTAAATCTCATAATGCCAGTGGTAACAGCTCATCTACGTCAACATCTACGACTGTGGCACGTCGTGGACGTATTAGTCGTCTTAAGCCGAAAGAGGAGAACTATACGATTAATGAATCCCTCGTGCAGTCTCATTCGCACTCTAATCAACAGCAGCAGTGCGAGCAGTATGCTAACGTCGCAAGCGATATGGACTATGTTGAAGAGTGCCAAGAGTTGCAGGCTTCAACAGCAGCTGTTAAACTTTCACAGGATCATTCACCTGCGCATCAGCGACATTATCCGATTATAGACGATAGCAAACCGTTTGTGTGTCAGCAGTGCGGTTTGGCGTTTGCACGAGAGAAAGCTTTGCTGTCGCATgctaaaAATCATCGCAACGATTCACCCTACGAATGCAaccaatgcaatgaagtgtttTGGGATACTGCCACACTGCAGGAACACCAAAAATCACATCACTTTGAAGAGAGCAATTCGGAGTACGACCCCGAAGAGGCCGAAGATACCCAAAGTGAATCTGAATCTGAACGTTTGTATGGCGAGTTTTATTGTAGCGAGTGCGGCATGTCATTTCATCGGCAGGATGTTTTGCGTAGACATGCACGTGCCCATCACAAAACTACTACTGCAGATGCAGTAACGACAGCAACCGGCGTAGAAGTGGACAACACTCATGATCAGCATTGCTGCAATACTTGCGGCGAAACATTTGCCGAAGCTTTAGATTTATTGGCGCATGCAGAAATTCATGCACGCTACCCACCTTTCAAATGTGTTCTATGCGGTGAAACCTTCTTTGAAGAACACACCATCAAACGGCATTTACAGAGTCAGCATGTTGGCGAAATGACACAAAACTCGTGCATCCTTTGCGGTAAAGAATGTCGCGATCGCAAGGCATTGATTAAACATGCTTGGGATCATTCGCGCGAGAAATGCCACTCTTGTTCGAAATGTGGCAAGAACTTCCATAATAAAGCACGTCTCAAGCGCCACATGGCATCACATCGCGACAAATCGGTTATTTGTGATGTCTGCCATGAGGAGTTCCCCGATGGTCGCACGCTCTCGAATCACCGGCACTCACACAGCGCAACCGCTTCTGGAAAGCTGTTTCCTTGTCATGAGTGTGGTAAAACTTTTGGTTCACGCAGTTCGCAACAGATTCATGTCCGCATACACACCGGTGAGCGTCCGTATGGTTGCCGTTTCTGCTGGAAGGCATTCGCCGATGGTGGCACAttgcgcaagcatgaacgcatACATACGGGCGAAAAACCATATGCATGTGCAGTGTGCCCGCGTGCCTTCAATCAACGTGTTGTGCTGCGTGAGCATATACGTTCACATCATTCTGGCTTGGATGCTAAACGTGGCACATACTTTTGTACGGTTTGCACTGCAGATTTGTCATCGTCTAACGATTTAATTCAACATTTAATACAACACAGTGACATGAATACTGCCATGCAGAGACAACCAGTTACTGGCCCGCGTAAATATAAACGTCGTAGAAAGCTGAAGCCACATGAGATTGCACGTTTACGCAGCGAAGGTCAACAGAATGGCAGTGACATTGATATATCAGATTTCGATATGGATACCGTAGATGACTTGTTAGGAATAGGAGTAACAACATCAAATACTAATAGTACAACAAATTGTAAAAGTAATATGAAAAGTGCTGGAGGAGATGCTGTTAGAAATAACcccaataacaataataataataataacagccaCAACAACAGTGGCAAACGATCTAccgaagaagatgaagaagatgagaacgatgacgacgatgagGTAGCAAGAGATGCAGGTACAGTTTCTAAAAAGGAGCGTTACAATTCTGCCAGCAGTAATTCAGATAAATTATGGCAAACAAAATTGATAAATTCAAATGATGAGAGTTATAAATCAATGCTATCAAATTTGGAGAATACACTGCAAAGCATTGATACCTTGGTAGTTAGCAGTATTGCCACTAAACATATtgtggaagaaaaaaaatcaagacatagaactaacaacaataataataacgacAATGTGGCTGACAGCAGCAGCACAGCCCAACGCACACAGCAAGTACAAATTATCAAAATGGAAACGAAATACACCGCAGATGTAACGACAACAGCCACGACGTCGTCATCATTATCGACGAAAACGCGAAAAAAGCCTGAAAAGTCGCCAAAATTGACCCGCCCACGTATGATACACACGGAGAAGTCGCGCATTTCCAACTCGGACGGTAGTCGGAAACGCTCGAAAACATTCATTACACGCACTGAACCTGCCAGCATAGAATTGCTTCCGAAATCATCATCCACCACAATGGTTGATGATTATGAGATTATCTCACCCGATACCAAGCCGCCAAATCAAATAAGTTCCAGTCCATTGCATATCAAACAAGAGAATGACCAGCACCAGCAACATTCGCAGCATCAGTCGCATGCACTCTCATCGCGAAATGGCGATTTGTATGATGCGCAATTATTACTCGAAGCCTCGACACTACGTAAGGCggtatatgaaaaattcaatccAAGCATAGTTAATGACTTGGAAGAAATCCTACGTTCGCCTATCAAATCGGATCGTGGTGAACGACATCGCTTTACCAGCGAGTCGTCAAGTCAATATCTTGTCGAGCCCGCAGAAGAGGAACAGCATTTAATTAAGATCGAACCAACCTCACCTGATTTGCGTGAGATTGTTGTCGGTAGTAGCGCGGGCAGAAATAGAaagaataacaacagcagcaactctGCTGAACGTCGTTCTACACGTTCAACACGCAATCGTCTCATCACTGCCAATCGCAAGTATTTAGAATTCGAAACCGATATTACCTCAAATAACACCAAAACAAATGCACCCAGCACAGcgcatcaacagcaacaaaaacgaaatgcGGCGACAACAAGTAAAAGTAAAGCTGTCAAAAATCCGAAGAAGGACaacattaaaactatttcaCCACCAACAGCATTGCCATCATCGCCTTCGAAATCATATTTGAATGATGCTCATGATTCAGTATCACCCTCATCTTCCTTTGCATCAATATCTGCAGTTGTTTCTGCTGCTGATGCAAATGCGGCCGCGGCAGCtgccgccgctgctgctgctggagCGGTATCAACACAACCGGAGCGAAAACAGCGTTATTTCGAATGCGAAATGTGCTCAGCGATATTCCCCGATCGTGCACAATTGCTCGATCATGTGCCCATACATATTTAA
Protein Sequence: MDGQSYGIQWIQHDMKTAGQMIIDAQPPHEEDILASSGDTDDGVQYLVDDDEHDGNVHVRATAADIDQIAAENLIFMARDGQMVTEIIGTDENGAVVVSASDGTTIDCEAVMQQAADMSSNDATEQHDDAGGGGCEYSEEYTETTPQMVTEEVITDDWVQHQGEERVEIPAEQIIGSNSHVLLDIEVPLPTMQDEYTALRPYPCDFCSRRFRKKASLNNHMVAHQHDRPNLCKLCGARFFRRGDLINHLKAHAEAPEVDGDFISFVEREHHQQRHHHANDHYYDQDWSVNTDAITGGYHHPGKSSRKSHNASGNSSSTSTSTTVARRGRISRLKPKEENYTINESLVQSHSHSNQQQQCEQYANVASDMDYVEECQELQASTAAVKLSQDHSPAHQRHYPIIDDSKPFVCQQCGLAFAREKALLSHAKNHRNDSPYECNQCNEVFWDTATLQEHQKSHHFEESNSEYDPEEAEDTQSESESERLYGEFYCSECGMSFHRQDVLRRHARAHHKTTTADAVTTATGVEVDNTHDQHCCNTCGETFAEALDLLAHAEIHARYPPFKCVLCGETFFEEHTIKRHLQSQHVGEMTQNSCILCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVICDVCHEEFPDGRTLSNHRHSHSATASGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACAVCPRAFNQRVVLREHIRSHHSGLDAKRGTYFCTVCTADLSSSNDLIQHLIQHSDMNTAMQRQPVTGPRKYKRRRKLKPHEIARLRSEGQQNGSDIDISDFDMDTVDDLLGIGVTTSNTNSTTNCKSNMKSAGGDAVRNNPNNNNNNNNSHNNSGKRSTEEDEEDENDDDDEVARDAGTVSKKERYNSASSNSDKLWQTKLINSNDESYKSMLSNLENTLQSIDTLVVSSIATKHIVEEKKSRHRTNNNNNNDNVADSSSTAQRTQQVQIIKMETKYTADVTTTATTSSSLSTKTRKKPEKSPKLTRPRMIHTEKSRISNSDGSRKRSKTFITRTEPASIELLPKSSSTTMVDDYEIISPDTKPPNQISSSPLHIKQENDQHQQHSQHQSHALSSRNGDLYDAQLLLEASTLRKAVYEKFNPSIVNDLEEILRSPIKSDRGERHRFTSESSSQYLVEPAEEEQHLIKIEPTSPDLREIVVGSSAGRNRKNNNSSNSAERRSTRSTRNRLITANRKYLEFETDITSNNTKTNAPSTAHQQQQKRNAATTSKSKAVKNPKKDNIKTISPPTALPSSPSKSYLNDAHDSVSPSSSFASISAVVSAADANAAAAAAAAAAAGAVSTQPERKQRYFECEMCSAIFPDRAQLLDHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01133120;
90% Identity: -
80% Identity: -