Tmul020229.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Toxonevra muliebris
Gene Symbol
Hr39
Assembly
GCA_963691655.1
Location
OY829329.1:4703800-4707814[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.1 9.5e+02 -0.4 2.4 132 186 48 93 6 147 0.71
2 4 0.37 3.5e+03 -2.3 8.8 69 172 222 339 200 347 0.75
3 4 3 2.8e+04 -5.4 5.6 55 157 372 470 344 480 0.48
4 4 9.9e-94 9.4e-90 302.6 10.1 1 408 594 971 594 971 0.82

Sequence Information

Coding Sequence
ATGTCTtcaattaaaacagaaaatgcCACCGTAACGACAACAACCACAAATATTCAACCACCTTCATCCACACCATATAGCCACAGCCTAATGTCAGTTGGAGGAGGCGGCAGTGCTTTTCAGCTGCCCATCAATATGAGCAGTCACCCCGCGACTAATCCTAGCGCTAACTCGAACCCTTCCTCATCCTCTTCCACCTCCGCCGCATCAACAACGACAATAACACGTCATAATGTGTCAGTGACAAATATCAAGTGTGAAGTAGACGAAGCAGCGCTAATGGCTGCCCATACATCCAACGGCAACATTGTGCCTGTGATTGCATCaacaagcagcagcagctgtaCAACCGGCGGCTATTATAATTGCGCAGGTACGAGCACAAGTGGTGGCAGCATACGCATACCGGTAACAAAAGCAGAAGACTCCGACTCCGAAGCAGAGCTTGCAAGTATTGAGAACTTAAAGGTAGCGCGTCGCACTAGCAGCAGCGCAGCGGATATAAGTGGAAGCAGTGGAAGCAGCGGTTGTACTGGTGGGGGAATCGGCGGGATTTTTGGTAGCAGCGGCAATAATtgtaatagcaataaaaatggACCACGTCCGATGTCATGGGAGGGTGAACTCTCTGAAACAGAGACGACTGAAACTGAGCTTATGGATACCGAACATCATTCGTTAAGCAATGGTGGCGTTTCCTCTGATATGATAAGTGTAAGCGGTGGCGGTGGTGTAGCAGTAATTAAAAGTGAAGCCACAACCACCACACCAACGGTGGCGGGAGCTAATGCAAGTGTAACGTCGCATCATCATCAAAATTCATACCATGCGCATTCGCATCACCAGCTGATAAAACCAGAGTTGGAACAGATTTCTGTAGAAATACACAATTCAGCTTCTTCGTCAAGTCTCTACTCTTCGCCACATgccacaaaattaaaattggcgCCCACGCAAAGTGACCCCATCAATCTGAAATATGAGCCCGATGCCAATGCGGTGAATTCACCAGTGCTGACACGAAACAAATCAACAACTTTGCCACTCCCTGCCAATCCCAGCCCTGATTCTGCCATACATTCCGTTTACACGCACAGTTCCCCCTCAGAATCGCCGCTCACATCGCGTCACGCGCCCTACACGCCATCGCTGAGTCGGAACAATAGCGATGCATCGCACAGCTCTTGCTATTCCTACAGTTCTGAGTTTAGTCCCACACATTCACCAATACAAGGGCGACATGCGCCACCGGCGAGTGCTGCCTCGTCGATCTACGGCAATTTTAATAGTTCGCTGCATCATTCCGTATTGTATCGTCCCATATCGACTGCAGAGGGAGCAGCAGCGGTGGCGGCGATTGCGGCAGCAGCAGCGGTAGCTTCAACTTCAGTGCTTCCTAATTCCAACTCAGAAGCGGCGCAAAATCTTTCGATGGATGCTCGCAGCGGCGGCGGTGGCGAAGTGCCAACACAATTGGGAGGCGGTAACAGCGTGACGGCAACCATTGGCGGTGTTGAAGGTCTGCCCTCATCAGCTGCTGGCATCTCTCGGCAGCAACTAATAAATTCGCCATGCCCCATTTGCGGTGATAAAATCTCGGGCTTTCATTATGGCATCTTCTCGTGTGAATCCTGCAAAGGTTTCTTCAAGCGCACCGTACAGAATCGCAAGAATTATGTATGCGTGCGTGGCGGTCCGTGCCCCGTGAGCATTTCGACACGTAAAAAATGCCCTGCCTGCCGTTTTGAGAAATGCCTGCAAAAAGGTATGAAACTTGAGGCCATACGTGAGGATCGTACACGTGGCGGACGTTCGACGTATCAATGTTCATATACCTTGCCCAATACAATGTTGAGCCCGTTAATGAGTCCAGAACAATCGGGTGGCTTAACTGCAGTAGCGACGACTAgccaacaacatcagcagcagcaacaacagcagcaccaacatATGCAACAGATGCATGCTGCAGCAGTAGCAGCTGCCCATCATCACCATCAGCAtggcggtggcggtggcggtGTTAATGGTTTTGGCATAGGTAACCCCACACAAATGATTAAAACTGAACAAAACGATGCGTCCGTATGCCGTGCTGGAAATGTGCCAATATTATTGCAGGAAATAATGGATGTTGAGCATCTTTGGCAATATAACGAAGCTGAGATTTCACGTTTCGCTGTTCAACCTTCACTCTCTTCCTCAAATTCAAATGCCTCTTCTACATCTTCCACTTCATCATCTTCTAGCAATCCACCTACGGCTCATCAAATGACGAATCCTTTGCTTGCTAGCGCTGGCTTCGGCGCTAATGGTGAAAATGCAAATCCGGATTTGATACAACATCTTTGCAAAGTCGCCGATCAtcgtttgtataaaattgtCAAGTGGTGCAAAAGTTTgccactttttaaaaatatttcgATTGATGATCAAATTTGCCTGCTTATCAATTCATGGTGTGAACTTTTATTATTCTCTTGCTGTTTTCGTTCAATCGATACTCCAGGAGAAATTAAAATGTCACAAGGCAAAAGGATTACATTAGCACAGGCCAAATCAAGTGGTACTCAGGCCTGCATTGAACGAATGCTTAATCTGACAAATCATTTGAGACGTCTACGTGTCGATCGTTATGAATATGTTGCCATGAAAGTTATTGTGCTACTACAATCTGATACATCAGAATTGCAAGAACCGGTAAAGGTGCGTGAATGCCAAGAGAAAGCGCTACAAAGTCTACAAGCATATACACTAGCCAATTATCCAGATACACCGTCCAAATTTGGTGAATTATTATTACGTATACCGGATTTACAAAAGACATGCCAGCTTGGCAAAGAAATGCTCACTATAAAATCCCCAGACGGTGGAGATTTCAATTTACTTATGGAATTGTTACGTGGAGAACATTGA
Protein Sequence
MSSIKTENATVTTTTTNIQPPSSTPYSHSLMSVGGGGSAFQLPINMSSHPATNPSANSNPSSSSSTSAASTTTITRHNVSVTNIKCEVDEAALMAAHTSNGNIVPVIASTSSSSCTTGGYYNCAGTSTSGGSIRIPVTKAEDSDSEAELASIENLKVARRTSSSAADISGSSGSSGCTGGGIGGIFGSSGNNCNSNKNGPRPMSWEGELSETETTETELMDTEHHSLSNGGVSSDMISVSGGGGVAVIKSEATTTTPTVAGANASVTSHHHQNSYHAHSHHQLIKPELEQISVEIHNSASSSSLYSSPHATKLKLAPTQSDPINLKYEPDANAVNSPVLTRNKSTTLPLPANPSPDSAIHSVYTHSSPSESPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHAPPASAASSIYGNFNSSLHHSVLYRPISTAEGAAAVAAIAAAAAVASTSVLPNSNSEAAQNLSMDARSGGGGEVPTQLGGGNSVTATIGGVEGLPSSAAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNTMLSPLMSPEQSGGLTAVATTSQQHQQQQQQQHQHMQQMHAAAVAAAHHHHQHGGGGGGVNGFGIGNPTQMIKTEQNDASVCRAGNVPILLQEIMDVEHLWQYNEAEISRFAVQPSLSSSNSNASSTSSTSSSSSNPPTAHQMTNPLLASAGFGANGENANPDLIQHLCKVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGKRITLAQAKSSGTQACIERMLNLTNHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLANYPDTPSKFGELLLRIPDLQKTCQLGKEMLTIKSPDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01470575; iTF_01132958; iTF_01132977;
90% Identity
iTF_01470575;
80% Identity
iTF_01470575;