Basic Information

Gene Symbol
-
Assembly
GCA_036873485.1
Location
JAYJLV010059411.1:928-1413[+]

Transcription Factor Domain

TF Family
HMGA
Domain
HMGA domain
PFAM
AnimalTFDB
TF Group
Unclassified Structure
Description
This entry represents the HMGA family, whose members contain DNA-binding domains, also known as AT hooks due to their ability to interact with the narrow minor groove of AT-rich DNA sequences. They play an important role in chromatin organisation [1]. The high mobility group (HMG) proteins are the most abundant and ubiquitous nonhistone chromosomal proteins. They bind to DNA and to nucleosomes and are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. They can be grouped into three families: HMGB (HMG 1/2), HMGN (HMG 14/17) and HMGA (HMG I/Y). The characteristic domains are: AT-hook for the HMGA family, the HMG Box for the HMGB family, and the nucleosome-binding domain (NBD) for the members of the HMGN family [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 5.2e-09 0.00019 22.9 4.5 5 20 137 151 135 152 0.89

Sequence Information

Coding Sequence
ATGTTGGCCCCGAAGTACGTTGGCCCATATGAGATATTAGAGAAGAGTGAGCCCAACACGTATAAATTGGTGGATCAGGAAGGAGACTTCGAAGGCCTGGTGCACGCGGAACACTTGAAGCCATTTTACGCCGGAAAGGAGTCCGAGGATAACGAAGAAGCGTCTTGTCTCAACAacagcgaagaagaagacgacgacgccCGACCACCGAGGGATGTTAGCGAAACGGCGATGAGCGACCCGCCTCCTGCAAGAAATCAGTCGCCAGCGGGCGCTGAGCGAGTTCAGCACGAGGTTGGCGTAGCTACGCAAGCTCACGGGAGGGGTAGGTCTAGAAAGACTGTCTTAGTCATTCAAAGGCAAGCCGATTCCACTCCTATATCAGCCAGCCCCGTGCCTGTTGCTAGCGAGCCCTCTAAACGACCACGTGGCCAACCGAAagggtcaaaaaatagtatactaaCCAAGCTACCCCGGTTCAACTAG
Protein Sequence
MLAPKYVGPYEILEKSEPNTYKLVDQEGDFEGLVHAEHLKPFYAGKESEDNEEASCLNNSEEEDDDARPPRDVSETAMSDPPPARNQSPAGAERVQHEVGVATQAHGRGRSRKTVLVIQRQADSTPISASPVPVASEPSKRPRGQPKGSKNSILTKLPRFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-