Tyan012698.1
Basic Information
- Insect
- Topomyia yanbarensis
- Gene Symbol
- -
- Assembly
- GCA_030247195.1
- Location
- CM058068.1:187310571-187312306[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0074 0.75 12.4 0.9 1 23 47 72 47 72 0.95 2 12 0.00042 0.043 16.3 0.9 1 23 80 102 80 102 0.94 3 12 0.02 2 11.0 1.7 2 23 111 133 110 133 0.95 4 12 0.08 8.2 9.1 0.5 2 23 192 214 191 214 0.95 5 12 1.2e-05 0.0013 21.1 0.3 1 23 246 269 246 269 0.93 6 12 0.0053 0.54 12.8 4.0 1 23 277 299 277 299 0.98 7 12 0.00025 0.025 17.0 4.7 1 23 307 329 307 330 0.95 8 12 8e-06 0.00081 21.7 0.3 3 23 338 358 336 358 0.95 9 12 0.89 90 5.8 1.0 2 21 369 388 368 389 0.93 10 12 0.0011 0.11 15.0 0.0 2 23 397 419 396 419 0.96 11 12 0.043 4.4 10.0 0.2 3 23 427 447 425 447 0.91 12 12 0.00041 0.041 16.3 2.7 1 23 453 476 453 476 0.97
Sequence Information
- Coding Sequence
- ATGAAACACTTTTGGTTTAAGACCGCAGATTGCCAGAACCAGTTCGTGTGCTGTAGTTGCTGGAAGAGGATATCGGATTTTCATCAGCTATACTGTGCGGTCGAGACGCGCTGGTTCTATGTTAAACCAGCTTTACTGTTCCGTTGCGAGGAGTGTGACCACTCAAAGGCCTTCAGCACTGAAACTGACCTGCAATTACACACTCTGTTGCTTCACTCCAAGGAAACCGACAAGGTACACAACTGCGATCAATGTGATAAATCTTTCGCCACCGAATGGCAGCTTTCTAGTCACAAAGCATGGCACCAGGATGTGGATAATTTGAATATTTCGTGTAACGTATGCAACAAACAATTTGCGTCAATGCACACCCGAAATGCTCATGTGCGGAATCAACATTCGGATTATTCGATAGCCAACATGGCAAAGGTAGTGATGACGCATGAAGAGGACAACGCTGACAGTATGCTGATAGCGACAACAGAGACAGAAAAGGAAACCGCtaagaaaatacaaaaatcggCTGAAACAATAGCTCAGGAGGATGAATTGATCCGACAATTCTGCAATTTGTCCTGTAAAAGGTGTGAGTATGTTGGTGATAATCTCTATCAACTTTTGAAGCACTATACAACCGATCACCAAATGCGTGGCTATGCGGAGTGTTGTGGAATTAAGTTTACTAAAAAACCTCGCTTATATAACCACTGTCAATTGCATGTGAATCCGAATATGTTTCAATGTGAGATATGCAGCAAAACCTTCTCTCAGAGTGAAGCGCTGGAACAGCACAATCAATGGGTACACACTCCTGACTCtgcaaaaccattcaaatgtgATATTTGTGACGCAgcattttgcaaaagttttcaGCTCCGGTTTCATATGAAGTACCACATtgccaaagaacaaaaaattttcCAATGCAAAGATTGCAACAAATCCTTTGGCACCAATCTTTTACTTCAAGCTCATCGCCACAACCATCACGGAGCTTTCAGCAATTGGGCTTGTGATATTTGCGGCAAAGGTTTCACGCACAAGGCACTGCTGGAAAAGCACTACCTTTTGCATTCGGAGCAAGGCGCTGCAAGTTTGATGGTACAGTGCGGACACTGTAGCAAGTGGCTGAAGAACAAGGACACCTATCAGAGTCATGTGAAACGATGCCTCGCCAGTGGCTCTATTACTTGTGATGTTTGCGGGAAAAAACTAGCGAATGAGCCGGCCTTGGCACGACACAAACGAGTCATACACCGGCATCGTCCAATGCTAGCATGTAGTTACTGTGGTAAAGCATACAAGGAAATTcggcgattgagagagcacgaAGCAAACCATCGTGGGGTCGTTTTGTACACGTGTCCTTACTGCCCGAAAACGAGTAATTCAAGTTCAACCATGCACAACCATAAGAAATCGGCTCATCCAGAGCAGTTCGCCGCTAGAAGGGCGGAACAAGCATGCATACAGTCGGATACATAG
- Protein Sequence
- MKHFWFKTADCQNQFVCCSCWKRISDFHQLYCAVETRWFYVKPALLFRCEECDHSKAFSTETDLQLHTLLLHSKETDKVHNCDQCDKSFATEWQLSSHKAWHQDVDNLNISCNVCNKQFASMHTRNAHVRNQHSDYSIANMAKVVMTHEEDNADSMLIATTETEKETAKKIQKSAETIAQEDELIRQFCNLSCKRCEYVGDNLYQLLKHYTTDHQMRGYAECCGIKFTKKPRLYNHCQLHVNPNMFQCEICSKTFSQSEALEQHNQWVHTPDSAKPFKCDICDAAFCKSFQLRFHMKYHIAKEQKIFQCKDCNKSFGTNLLLQAHRHNHHGAFSNWACDICGKGFTHKALLEKHYLLHSEQGAASLMVQCGHCSKWLKNKDTYQSHVKRCLASGSITCDVCGKKLANEPALARHKRVIHRHRPMLACSYCGKAYKEIRRLREHEANHRGVVLYTCPYCPKTSNSSSTMHNHKKSAHPEQFAARRAEQACIQSDT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01462529;
- 90% Identity
- iTF_01462529;
- 80% Identity
- -