Basic Information

Insect: Topomyia yanbarensis
Gene Symbol: Znf516
Assembly: GCA_030247195.1
Location: CM058069.1:170847928-170867294[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00018 0.018 17.4 0.3 3 23 173 193 171 193 0.98

2 14 0.0099 1 12.0 4.4 1 23 199 221 199 221 0.96

3 14 4.5e-06 0.00046 22.5 0.4 1 23 230 252 230 252 0.98

4 14 4.9e-06 0.0005 22.4 6.4 1 23 258 280 258 280 0.99

5 14 0.0095 0.97 12.0 0.2 2 23 288 309 287 309 0.97

6 14 0.00039 0.04 16.4 7.4 1 23 315 338 315 338 0.98

7 14 0.0046 0.47 13.0 5.9 1 21 344 364 344 365 0.94

8 14 0.054 5.5 9.7 3.0 3 23 373 394 371 394 0.94

9 14 3.6e-05 0.0037 19.7 0.8 1 23 418 440 418 440 0.97

10 14 0.00016 0.017 17.6 0.1 1 23 451 473 451 473 0.94

11 14 0.016 1.6 11.4 0.9 1 23 503 525 503 525 0.99

12 14 0.0013 0.13 14.8 3.1 1 23 588 610 588 610 0.98

13 14 6e-07 6.1e-05 25.3 1.4 1 23 618 640 618 640 0.99

14 14 0.025 2.5 10.7 0.8 1 23 646 669 646 669 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00018	0.018	17.4	0.3	3	23	173	193	171	193	0.98
2	14	0.0099	1	12.0	4.4	1	23	199	221	199	221	0.96
3	14	4.5e-06	0.00046	22.5	0.4	1	23	230	252	230	252	0.98
4	14	4.9e-06	0.0005	22.4	6.4	1	23	258	280	258	280	0.99
5	14	0.0095	0.97	12.0	0.2	2	23	288	309	287	309	0.97
6	14	0.00039	0.04	16.4	7.4	1	23	315	338	315	338	0.98
7	14	0.0046	0.47	13.0	5.9	1	21	344	364	344	365	0.94
8	14	0.054	5.5	9.7	3.0	3	23	373	394	371	394	0.94
9	14	3.6e-05	0.0037	19.7	0.8	1	23	418	440	418	440	0.97
10	14	0.00016	0.017	17.6	0.1	1	23	451	473	451	473	0.94
11	14	0.016	1.6	11.4	0.9	1	23	503	525	503	525	0.99
12	14	0.0013	0.13	14.8	3.1	1	23	588	610	588	610	0.98
13	14	6e-07	6.1e-05	25.3	1.4	1	23	618	640	618	640	0.99
14	14	0.025	2.5	10.7	0.8	1	23	646	669	646	669	0.96

Sequence Information

Coding Sequence: ATGGACTACAACACGTTCAGCAATAAACACTACTCCGTCTCAAACTCATCGGTACCTGCTAGTACCGGGTTTTTCCAGCCAAGTTCTTCCGGCGGCTTTCTGAAAGTGCCCAATCCCAGCGTCATTCTGAAGCAGGAAAATGTACCATCGGGATCACAAAGTGGAACTGCTACTCCACCCGTGAACTACAGTCAAAATGCCCCAATTTACGAGCAACACCCACATCATCCGGACACGAAGCCGGTTTATTATGCGAAACCACTCGATCTGCAGCTTATATCGAATCATTACCTGTCGCATCCGCAGCAGAACGCTACCGGTCAGCAGCCCGCTTCGTTCCATATGGCACACGAGTATCATCATGATCACTCCAACGCGTCGACGATTAGCTCGGGGGTAGATCAGCACCGATCGTACAGTGTGGAACCTGCGCCGGTTCATCCTGGCCAGCCAGGAGCAATTCTTCAGCATCATGCGGCTGTTCCAGTAGCTCCACCACCCAAGATTAGTTATGGTTGCGAGATCTGCGCGAGGACTTTCGATTCCAAGGCAAAGTTGGAGAAACACTATCGGATTCACAACGAAGAACCGACCTTTGAATGTCGGATGTGCGAGAAGAAATTTCGTAGCCAGAGCACTCTCACTTGCCACGAGAAGGTGCATGGGGAGAACGGAGTGGATAATAATTTCTCCTGTGTGACCTGTGGGAAAGTTTTCAAGTCGGAAGATAAACTGCTCATCCATATGCGATTGCATACGGGTGAAAAACCGTATCAGTGCAAAATCTGCTTCAAGTGCTTTAATCACCAGTCGAATCTGATAGCTCACTCACGAACGCACGAGACGATCAAAAAGGCCATCAAATGCGACCGATGCAACAAGGTGTTGGACAACGAGCAACGTTTGGCGATTCACATGAGACTGCACACCGGAGAGAAACCTTACAAATGTTCGTATTGTGATAAACGATTCAACCACAAGAGCACGGTTTGCACTCACGAGAAGACGGTACACATTGCCTCCAACGCATACAAGTGCGAACGGTGCCACAAGACGTTCAACCAGAAGTGTCAGCTGCAGTATCACGAGAAGCTGCAGGAACCGCACGTTATCGCGTGTACTATGTGCGACAAGGTATTTTGCTACCAGGCCAGCCACAAGGAGCACATGTTTAAGATCCATTTTCCGCGATCGAAGAAAGACCGCTTTGTCAGCGGTGTCGTAGAGGGCGAAGGCAGTGGACGCAACAAGTTCAAATGTAACGTCTGCGATCGAAGGTTCTACTACAAGCGGGCCCTGGAGATGCATATGGGTGTTCACGACTCCTCGCTGGACGTCAATGTGCTTTACTTTTCGTGTAACTACTGCCCGGAGACATTTACCGACGAGGATCCGTTGCAGAAACACGAAGCGGAACACGTCGCAAACAACACGActgatttcatggagaatctcaAATCACTGGAACAGTACGAGGATCCGGAAAACGGCCAAGTAGAGGGCAAATACCGCTGTCCACTGTGCTTTAGTCGCTTTGATGATATTCCAGCCCTACAAGAGCATCACAAGACACATCTCTGCTCCAATCCGGAGGAGTGTGATAAATGCAAGCCTACGCTTGCGGAAGATTACGACTTCACGAAAAGCACTTACGATGAGAACGATGATAACCAGCCGACGCAATGTCACCTTTGTGAGCGAACTTTACAATCTTTCGAACTGTTTCAGAACCATTTCCACTATCACACCTCGCGGGTTCCCTTCTACTGTTATCACTGCCGGGAGGAATTTCCCGACAAGAAAGAGCTGTATGCGCACACTAAGACACACGCTCCAAGAGACGCGGAGTCGTATACGTGCGAGATATGTGCCAAAGTTTTCTCGACCAAGGGTAACTTCCGGCGACATCTGAAGTCACATGAAGCAATTCGAGCCTTTGCGTGTGATCGATGTTTCAAGCAATACGACTACAAAAGTGCACTGGACCTGCACCTAAAGAAAGCTCACGGAATTGACTACTCTTGA
Protein Sequence: MDYNTFSNKHYSVSNSSVPASTGFFQPSSSGGFLKVPNPSVILKQENVPSGSQSGTATPPVNYSQNAPIYEQHPHHPDTKPVYYAKPLDLQLISNHYLSHPQQNATGQQPASFHMAHEYHHDHSNASTISSGVDQHRSYSVEPAPVHPGQPGAILQHHAAVPVAPPPKISYGCEICARTFDSKAKLEKHYRIHNEEPTFECRMCEKKFRSQSTLTCHEKVHGENGVDNNFSCVTCGKVFKSEDKLLIHMRLHTGEKPYQCKICFKCFNHQSNLIAHSRTHETIKKAIKCDRCNKVLDNEQRLAIHMRLHTGEKPYKCSYCDKRFNHKSTVCTHEKTVHIASNAYKCERCHKTFNQKCQLQYHEKLQEPHVIACTMCDKVFCYQASHKEHMFKIHFPRSKKDRFVSGVVEGEGSGRNKFKCNVCDRRFYYKRALEMHMGVHDSSLDVNVLYFSCNYCPETFTDEDPLQKHEAEHVANNTTDFMENLKSLEQYEDPENGQVEGKYRCPLCFSRFDDIPALQEHHKTHLCSNPEECDKCKPTLAEDYDFTKSTYDENDDNQPTQCHLCERTLQSFELFQNHFHYHTSRVPFYCYHCREEFPDKKELYAHTKTHAPRDAESYTCEICAKVFSTKGNFRRHLKSHEAIRAFACDRCFKQYDYKSALDLHLKKAHGIDYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01471726; iTF_00949050; iTF_01525152;
90% Identity: -
80% Identity: -