Basic Information

Gene Symbol
-
Assembly
GCA_030247195.1
Location
JASDBJ010000041.1:19599-22480[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.046 4.7 9.9 0.6 1 23 156 178 156 178 0.98
2 14 0.019 1.9 11.1 4.8 1 23 183 205 183 205 0.97
3 14 0.00023 0.024 17.1 1.6 1 21 222 242 222 245 0.90
4 14 7.4e-07 7.5e-05 25.0 2.0 1 23 251 273 251 273 0.98
5 14 1.5e-05 0.0015 20.8 4.4 1 23 279 301 279 301 0.98
6 14 0.0041 0.42 13.2 0.4 1 19 307 325 307 328 0.94
7 14 0.00086 0.087 15.3 2.2 1 21 334 354 334 356 0.95
8 14 3.8e-07 3.9e-05 25.9 1.1 1 23 365 387 365 387 0.99
9 14 1.7e-06 0.00017 23.8 0.4 1 23 393 415 393 415 0.98
10 14 0.00034 0.035 16.6 1.9 1 21 422 442 422 443 0.95
11 14 0.00028 0.029 16.8 1.2 1 23 524 546 524 546 0.98
12 14 6.4e-07 6.5e-05 25.2 1.9 1 23 564 586 564 586 0.98
13 14 0.0022 0.22 14.0 0.6 1 23 593 615 593 615 0.97
14 14 0.00012 0.012 18.0 3.2 1 23 623 645 623 645 0.98

Sequence Information

Coding Sequence
ATGGCAGAAGATTTATCGATCAATAAAAATAAGATCTGTTCTTCGCGCTATGCCAACAACTACATCTGCCGTTTGTGCTTGAAAAATGAGGCCCATATGGAACCGCTGTTTTACGCGAATCTATTTCCGAACATTTTGCTCACCAAAAAGATATACGATTGCACGTCGATACAGATCATTTTCGAACGTAACCTGCCGATGTTTGTTTGCAAACTTTGCGCCAACAAGTTGGACGAGTATATCCGTTTTCGTGAACGCTGTGTGGCAAACGATGAATTTTTAAGGAATGCTCTAGCATTTTTCGATGCCGGGCAAAACATCATTAAAACGGAACAGGAGCTGGCTCCTTCCTCAGCCCAATTACAACAACATGCGGGCCCAATCGATTTTCGCCAAATTAAAAGTGCTGTTGATTCAGAATCATTTGAACAGGCAGACGAGGACGAACAATTGGAAACGGAGCAATTCTCCTGCAATGAATGTGATTTCATAACAGGTGATGAATCCACTATACGTACTCATCAGAAACAGCACGAAGATAGACCTTACGCATGCACGATGTGCTCGAAGTCGTTCAAGATTCGACAACATTTGCTGATTCACAGCCATACGCACGTAGATCTACAGCAGCGAATAGAACAATCGGTCGACATGAAGCCCACCTACAGTTGTTCGAAATGCACCAAGGTTTTTATCAACAGAGGAAACCTGATAAATCACTCGGCCGAGTGTCACGGTAACGTAAAGAATTTCAGTTGCGAAATCTGCTTCAAATCATTCAAGTACAACGTCCAACTGCGGATTCACATGAGAACGCACTCCGGAGAACGGCCACATACATGTGAAATTTGTCACCGTGGATTTTCTCAGCTTTCGAATCTGAGGTCTCACCGAAAGGTACACTCGAAAGTTAAACCGTACAAATGTCAGCTGTGCCTCAAGAGTTTCACCATGCTCGATAACTTATCGGTGCACAGCTTGAAGTGCGTTAAGGATAAGTACCGCTGTACGCTGTGCTCGAAATCATTCGCAAAAGAAGGCAATTTGATCTCACACTTGCAGTGCCACAGTGAAGGAGTGGTGGAGAAAAACTTCAAGTGCGAAATGTGTCCCAAGAGTTTCAAGAACAAGGAGGATTGGAAGCGGCATGTTCGGGTGCATACAGGCGAAAAACCTTACATCTGCGACATCTGTAACAAAGGCTTCGCGCAAAAGGCCAATCTCCTGTCGCACCGGAAAACCCATCTCAAACCGGAGATTGTGTTTAAGTGTGAGCGCTGTGACAAAGTTTGTCGAACTCAGAAGTTGCTGGAAATGCACATACAGAAATGCGGTACACTTGAATTAAAAACTGCAACACCGCCGGTTTCGGAGCTGCCAACTCCAACCCAATCACCGATGGTATCCGTACCGCCGCCAACATCTGTGACACCAACATTAGAAGCTTTGTCCGACCTTTTGCGGTATGAAATCGCTATGCGTGCTCCGACTGAACTGCAAGAGATGCTGCTGGCTACGATGGAGAAAAAGAAAGCAGCTAAACAGAATACGACGACCGGTAACCGAAACTACCGGTGTGAAGTGTGTTTTAAGGTATACTCGCAGTATCCGAGTTTGGTAAAACACCGGAAGTTACACCTGAAAGGTGCTCGCTTACGGACGAAATCAACAGAAGCGGACGATCGACCGTATTATTGTGATATCTGTGGGAAGAATTTTAAGTTTAACAGAAATCTAAAGGTTCACATGAAGCTACACACCAAATCAAATGGCTGTTTCAAGTGCGACAAATGCAGCAGCACATTCGAACTGGCCGACCAACTGAAGAATCACCTGTTGGAGCATCCCATCGACATGGAGAAGATCTTCAATTGTGAATTCTGTTCGAACACATTCAAATCGAACGAAGATTTGAAGCGACATCGGAGATCCCATACGGGTAAGTGA
Protein Sequence
MAEDLSINKNKICSSRYANNYICRLCLKNEAHMEPLFYANLFPNILLTKKIYDCTSIQIIFERNLPMFVCKLCANKLDEYIRFRERCVANDEFLRNALAFFDAGQNIIKTEQELAPSSAQLQQHAGPIDFRQIKSAVDSESFEQADEDEQLETEQFSCNECDFITGDESTIRTHQKQHEDRPYACTMCSKSFKIRQHLLIHSHTHVDLQQRIEQSVDMKPTYSCSKCTKVFINRGNLINHSAECHGNVKNFSCEICFKSFKYNVQLRIHMRTHSGERPHTCEICHRGFSQLSNLRSHRKVHSKVKPYKCQLCLKSFTMLDNLSVHSLKCVKDKYRCTLCSKSFAKEGNLISHLQCHSEGVVEKNFKCEMCPKSFKNKEDWKRHVRVHTGEKPYICDICNKGFAQKANLLSHRKTHLKPEIVFKCERCDKVCRTQKLLEMHIQKCGTLELKTATPPVSELPTPTQSPMVSVPPPTSVTPTLEALSDLLRYEIAMRAPTELQEMLLATMEKKKAAKQNTTTGNRNYRCEVCFKVYSQYPSLVKHRKLHLKGARLRTKSTEADDRPYYCDICGKNFKFNRNLKVHMKLHTKSNGCFKCDKCSSTFELADQLKNHLLEHPIDMEKIFNCEFCSNTFKSNEDLKRHRRSHTGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00949006;
90% Identity
iTF_01462296;
80% Identity
iTF_01462296;