Basic Information

Insect: Topomyia yanbarensis
Gene Symbol: Zbtb8b_1
Assembly: GCA_030247195.1
Location: CM058070.1:10062963-10064411[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.16 17 8.1 0.4 3 23 11 30 9 30 0.95

2 16 2e-05 0.002 20.5 0.4 1 23 36 58 36 58 0.98

3 16 0.00034 0.034 16.6 1.8 1 23 64 86 64 86 0.97

4 16 6.6e-06 0.00067 22.0 2.3 2 23 106 127 106 127 0.97

5 16 2e-07 2e-05 26.8 1.6 1 23 133 155 133 155 0.99

6 16 6.8e-06 0.00069 21.9 1.7 1 23 161 183 161 183 0.98

7 16 2.9e-07 2.9e-05 26.3 0.7 2 23 190 211 189 211 0.98

8 16 9.9e-06 0.001 21.4 0.4 1 23 217 239 217 239 0.98

9 16 0.0026 0.26 13.8 1.7 1 23 245 267 245 267 0.96

10 16 1.7e-08 1.8e-06 30.1 0.4 1 23 273 295 273 295 0.97

11 16 1.2e-05 0.0012 21.1 3.4 1 23 301 323 301 323 0.98

12 16 2.4e-05 0.0024 20.2 3.6 2 23 330 351 327 351 0.94

13 16 0.00029 0.03 16.8 1.2 1 23 357 379 357 379 0.97

14 16 1.6e-05 0.0016 20.8 0.8 1 23 385 407 385 407 0.98

15 16 8.6e-06 0.00088 21.6 2.6 2 23 414 436 413 436 0.97

16 16 2.2e-05 0.0022 20.3 5.6 1 23 442 464 442 464 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.16	17	8.1	0.4	3	23	11	30	9	30	0.95
2	16	2e-05	0.002	20.5	0.4	1	23	36	58	36	58	0.98
3	16	0.00034	0.034	16.6	1.8	1	23	64	86	64	86	0.97
4	16	6.6e-06	0.00067	22.0	2.3	2	23	106	127	106	127	0.97
5	16	2e-07	2e-05	26.8	1.6	1	23	133	155	133	155	0.99
6	16	6.8e-06	0.00069	21.9	1.7	1	23	161	183	161	183	0.98
7	16	2.9e-07	2.9e-05	26.3	0.7	2	23	190	211	189	211	0.98
8	16	9.9e-06	0.001	21.4	0.4	1	23	217	239	217	239	0.98
9	16	0.0026	0.26	13.8	1.7	1	23	245	267	245	267	0.96
10	16	1.7e-08	1.8e-06	30.1	0.4	1	23	273	295	273	295	0.97
11	16	1.2e-05	0.0012	21.1	3.4	1	23	301	323	301	323	0.98
12	16	2.4e-05	0.0024	20.2	3.6	2	23	330	351	327	351	0.94
13	16	0.00029	0.03	16.8	1.2	1	23	357	379	357	379	0.97
14	16	1.6e-05	0.0016	20.8	0.8	1	23	385	407	385	407	0.98
15	16	8.6e-06	0.00088	21.6	2.6	2	23	414	436	413	436	0.97
16	16	2.2e-05	0.0022	20.3	5.6	1	23	442	464	442	464	0.98

Sequence Information

Coding Sequence: ATGCCTAGGAAGCAGCGGAAGCGAACAGACTGTGAGGTATGTGGCAAAGAAATGCTTCAGAAACAGCTCAAGCGACACCTTGCTACCCACTCTGGTGAGCGGCCGTACAAATGTGACATCTGCGACAAATTATTCACTCGGCGGGACGGCCTAGTTTCACATAAACTTATTCACACGAGTAGTCTACCGCATAAGTGCGATGTGTGTGACAAAGTGTTCCTTCTAAAGGAGAGCCTGCGGCGGCATATGTTTGTCCATACTGAGGGACGAGCACCCAAGCAACTTGGTAAATCGACCTCGGACATGCTGTGGAATGAGTGTGAAATATGCGGCAAAAAATTCCACCAAAAATATTACCTGCAGCAACATCTGTTAACCCACACTGGCGAGGAACCTTATAAATGTGATATATGTGGCAAAgcatttattcaaaaaaataacCTTCATAAACACGTCTTAACCCACACTAACGAGCGGccatataaatgtaaaatatgtGACCAGGTATTCAATCAAAAGATTACCCTGCAACGACACGAGTTCACGCACACTGGCGAGCGTCCAAACAAATGTGAAATATGTGGCAAACTATTTATTCAAAAGTCGAACCTGCAGCGCCATTTGATCACCCACACTGGCGAGCGCCCGTACAAATGTAGAATATGTGACAAAATGTTTGCCAACCGCGATTCCTTAGTTGAACATAAACTTATTCACAGTGTTGATCGTCCGCATAAATGTGACATGTGTGGCAAACAATTCATGTTGAAGAGTCGCCTAAAGCTACACGTTTTAGCCCACACTAGTGAGCGGCCGTACAAATGTGATATATGTGGCAAAGCATTTAAAAGGCAGAGTAACTTGAACGCGCACAGAGTCATTCACGATAGTGACCAACCGCACAAGTGCGAGATATGTGGCAAAAATTTCCCTCGCAAGCATGCCCTGAAGCTACACGTCTACACTCATACAGGTGGGTACCCATGCAAATGTGATGTATGTGGCAGAGCATTTTACCAGCAGTATCACTTGACTTTGCACAAACTCACTCACAGTAGTGAAGTGCCGCATAGCTGTGAAGTATGTGGAAAAAAGTTCCTTCAGAAGGGTGAGCTGCAGCTACACAGAATTACTCACACTGACAAGCGGTCATATAATTGTGAAATATGTGGcaaattattcatacaaaaaaCTAAAATGCAACAACACATGATCACCCACACTGGTGAGCACCCGAACAAATGTGATATTTGTGGTAAAACATATAAACAGCAGCATGACTTGAACTTGCACAGACTTACTACTCATAATAGTGAGCAGTCGCATAAGTGCGACATATGTGACAAAAAATACCGCCACAAAACTTCACTGCGGCGACACGTTGCAACTCACACTGGCAAGTGTTCATCAGAGGATACAATATGTGAATTTACAACCGCACCAGTGTGA
Protein Sequence: MPRKQRKRTDCEVCGKEMLQKQLKRHLATHSGERPYKCDICDKLFTRRDGLVSHKLIHTSSLPHKCDVCDKVFLLKESLRRHMFVHTEGRAPKQLGKSTSDMLWNECEICGKKFHQKYYLQQHLLTHTGEEPYKCDICGKAFIQKNNLHKHVLTHTNERPYKCKICDQVFNQKITLQRHEFTHTGERPNKCEICGKLFIQKSNLQRHLITHTGERPYKCRICDKMFANRDSLVEHKLIHSVDRPHKCDMCGKQFMLKSRLKLHVLAHTSERPYKCDICGKAFKRQSNLNAHRVIHDSDQPHKCEICGKNFPRKHALKLHVYTHTGGYPCKCDVCGRAFYQQYHLTLHKLTHSSEVPHSCEVCGKKFLQKGELQLHRITHTDKRSYNCEICGKLFIQKTKMQQHMITHTGEHPNKCDICGKTYKQQHDLNLHRLTTHNSEQSHKCDICDKKYRHKTSLRRHVATHTGKCSSEDTICEFTTAPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01462923;
90% Identity: iTF_01462923;
80% Identity: iTF_01462923;