Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.22 1e+04 -2.6 1.0 28 37 42 52 40 52 0.78

2 3 5.4e-28 2.6e-23 82.6 0.6 1 51 57 107 57 108 0.98

3 3 0.31 1.5e+04 -3.0 0.6 13 33 163 184 155 189 0.51

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.22	1e+04	-2.6	1.0	28	37	42	52	40	52	0.78
2	3	5.4e-28	2.6e-23	82.6	0.6	1	51	57	107	57	108	0.98
3	3	0.31	1.5e+04	-3.0	0.6	13	33	163	184	155	189	0.51

Coding Sequence: ATGCCGAAAAAGAAGTCTCTGGAATCGGACTCTGATAGCGATTCAGGCCCAGACGATAGAAATCCACCGCCATCAAAAAAGGTCAAGGAGGACGCAAAGTCTTCGTCCTCGGCGAAGGCCCCAAAATCTAAGGGCAAGGAAAAACCCAGCGACAAACAGCAGACGAAGTGGCAGCTGGAGAAGATGCGATTTGTGAACATCAACGAATTTCGCGGCCGGAAGATGGTCGACATCCGGGAGTTTTACGAGAAGGACGGGGATACGTTGCCGGGCAAGAAGGGGATCTCCCTCTCCGTCGTCCAGTGGAAGAAGCTCCTGGAAGTCGCCGAGGAGacATCTCTCAGTAAGAGTGGATTTTGCACAATTCAACTTCGAGGGCAAAAATTCGGTGCATGGTTGGGTTCTTCAAATATCGGCATTTTATTagAGACCGCTGGCGAAAACGATCGCGGCAAGCTCCTGGATTCGAAGCGGGAAAGGGAAAAGACCTGGAATGACGAAGAAAAATTACGGGAGAGGCGGGCTAAGGAGGACCAGGAGAAGAAATCGAAGCAGCGCAGCAAGGGATCTTCGGGCACCAttcTTCAGCTAATTCCGGACTTGAAGCTAAGCTGGGTTGTGTACGGGACTATTGCATCCACGTTCCACATTTTCCCGGCGCTCGAACCGACCTGGTTTGGGACCTGGGTGCGAGGTAAAATTCTAGCCAAGACGCGTACCACTCGGAGCTTACGGTCGTCCGGTAAGCTCGGCCCGGTGGCGGTCCTGGCTAAAATTTTACCTCGCAGCAGGGTTCCGAACCAATTATACCCGGCACCCAAACCAAATTGGTTTGGGTCCTAG
Protein Sequence: MPKKKSLESDSDSDSGPDDRNPPPSKKVKEDAKSSSSAKAPKSKGKEKPSDKQQTKWQLEKMRFVNINEFRGRKMVDIREFYEKDGDTLPGKKGISLSVVQWKKLLEVAEETSLSKSGFCTIQLRGQKFGAWLGSSNIGILLETAGENDRGKLLDSKREREKTWNDEEKLRERRAKEDQEKKSKQRSKGSSGTILQLIPDLKLSWVVYGTIASTFHIFPALEPTWFGTWVRGKILAKTRTTRSLRSSGKLGPVAVLAKILPRSRVPNQLYPAPKPNWFGS

Sequence clustering based on sequence similarity using MMseqs2