Tver062045.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula vernalis
Gene Symbol
topi
Assembly
GCA_958295665.1
Location
OY282558.1:458373167-458377423[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 5 2.8e+03 2.4 0.4 1 23 275 297 275 297 0.93
2 25 0.0017 0.93 13.4 1.0 1 23 329 351 329 351 0.99
3 25 0.0029 1.6 12.6 2.0 1 23 357 380 357 380 0.96
4 25 0.0006 0.33 14.8 0.2 1 23 386 408 386 408 0.96
5 25 3.2e-06 0.0018 21.9 1.6 1 23 414 436 414 436 0.98
6 25 0.00028 0.16 15.8 0.1 1 23 441 463 441 463 0.97
7 25 0.0015 0.85 13.5 3.6 1 23 469 491 469 491 0.97
8 25 0.083 46 8.0 1.4 1 14 497 510 497 513 0.88
9 25 0.0089 4.9 11.1 1.1 1 23 523 546 523 546 0.96
10 25 0.00029 0.16 15.8 1.1 1 23 604 627 604 627 0.96
11 25 0.67 3.7e+02 5.2 0.9 1 23 633 656 633 656 0.84
12 25 4.5e-05 0.025 18.3 1.8 1 23 662 684 662 684 0.98
13 25 0.22 1.2e+02 6.7 0.3 1 10 691 700 691 701 0.91
14 25 0.6 3.3e+02 5.3 2.8 2 23 728 750 727 751 0.92
15 25 0.22 1.2e+02 6.7 0.6 2 23 754 776 753 776 0.96
16 25 0.0011 0.6 14.0 1.1 1 19 839 857 839 858 0.97
17 25 8.7e-05 0.049 17.4 0.4 1 23 900 922 900 922 0.94
18 25 0.00033 0.18 15.6 0.1 1 20 926 945 926 946 0.96
19 25 0.022 12 9.9 0.6 3 23 963 986 961 986 0.86
20 25 0.11 62 7.6 0.4 2 23 993 1014 992 1014 0.96
21 25 0.00012 0.069 16.9 0.3 1 23 1018 1040 1018 1040 0.97
22 25 0.029 16 9.5 5.8 1 23 1046 1068 1046 1068 0.97
23 25 5.7e-05 0.032 18.0 1.2 1 23 1074 1096 1074 1096 0.99
24 25 0.0022 1.2 13.0 6.5 1 23 1102 1125 1102 1125 0.97
25 25 0.11 59 7.7 0.3 2 20 1127 1145 1127 1149 0.94

Sequence Information

Coding Sequence
ATGAACAAACTAACTGAAGATAATGCactttgtttatataaatgcgAAAATAATGACGGAGAAGAGGAAGAAGATGTCGACCAAATCCAAGATGAAATCATCGAGGTGGATTTATACTCGCTATGTCGAATATGCGGTAATATGCATGACACTTTAGTCCCGATTTATGCGGATCAGGGGCTAGAGTTGGAGCTAAgcacgaaaataaattattatttgccaaTTGATGTTACCGAAGAGGATATTCTACCACTTAAGATATGTTCCAATTGTGCTACTACAGTCACATTCTGGCATGAATTCGTCGCCGAATGCTGTGAAGCTGACAAACGATTCAGTATCATGCTGCAGTCGAGTATGATTGAGGATACGAAGCCAGAAGTAGCCGCTGAAAATATACAAGATGAGGTCAACGAAATAGACAATTCTGATGAAAACCAAACCATGGATACGGAAACCCAAGGAACAGAATATTTAGAAGAAACCGAATATGAGAATGatgaaaatattccagaaaGGTTGCCGGTTGAGGAGGTGGAATTAGATGAACATTCAAACGGACTGGAATCAATACTGGAAGAGGATACAGAAGAACAAAGCAAACCGAATAAATCACCCGACACTGCCGTAACAAGAACACGATgctcaaaaatcatttcaaccaTAGAAACCTCTCCTAAAACATCATATTTTCTAAACTCTAAGGATTCAGCTAAGCTTGACGAGCTTGTTAAAAAATCTAATCGCTCCGGGAATATGCGCCTCTCGAATGAAATTCTCGATGAAATTCGCTTGAATTTAAAACTAGAAGAGGATGGTGTGTACAAGTGCTACGAGTGTGAATTCGATACAAACGAACGGGATGTGATGGAAGGACATTTGAGGCAACACTTTCAgaacacattaaaaaaattgaaacagacTATGAAGCTTAAGGCGAAATTTTTTGacgagaataaaattgaaatggatGGTAAAACGTTATACGAGTGTCCCGAGTGTAATAAACGTTTGCACGCGACAAGTACATTCCTCTGGCATATGCGGATTCATACGGGGGAAAAACCATACGTTTGCTATATGTGCGGGAAAAAATTCCGAGTCTATCATGGGATTTCGCGACACATCAAAGAGACGCATATGAAGACAAAAGACTTTGCGTGCGATATTTGTGGCCGCCTATTCTCGAATAGGCGTAATGTCGCCGAACACCGGAATTTGCATTCAAACGAACGGCCTTATACGTGTGGTACATGCGGAAAGTCGTTTAAACAGCAGGCTTCCTTATTTATGCATAAACGACTACATCAACCGCATCAATATAAATGCGAGGAGTGTGGGTTAGGATTCCGGATTAAAAGTTCACTGCTTGTGCATGCCACGGTACATACAGGTGTCAAAGACCATGAGTGTGATATATGCCAGAAACGATTTCGTATCAAGCATGAGTTAAATCTTCATAAGCTGGTGCATACGGATTTTAAGCCGTTTGCATGCGAAAAATGTGGGCAGTCGTTTAAACAGAAGCGATTTTTTGTCTCGCGTAACGCGACCACTTCCATCCAATACAAATGCAAATTTTGTCCGATGATCTTTGTCGAAAAGTCCCGATTCAACGAACACACGAAGCTCGCACATTCCGAACTTATATTCCATTGTGATATGTGTAACGAGCTGGTCGAACGTAACCTTCTCATTTCACATATGACTGAGCACGCCGTGGAAGAGGTTCGACTAATAAACGAGCAGATCGAGAGTAAGAAAATTTTGGCCACACCTGATCTCGAAACTTTAcgaaaaaattttcagttcaaGTGTGATTCTTGCCCAAAAATGTTTGTCACCAAAACTGGGCTGCGGTATCACGTGAATCAGACACACAAAATGCTGCGACGATATAAGTGTGCAGAATGTGGGAAATTATTCGGTTGTAATCGTATTCTACGCAATCATATACTGAGCGTACATTCTAACGAGCGATCGTATAATTGTGAATTATGTCCGAAATCATTCAAAACCGATTCGTCTTATTACATTCATAGGCGGACTCATGACGTGAAAATTGCCGCTTTTCCGTGTGATATATGCGGCAAAGCATTCAAttgTGATTTCGATAGCGTCAAGGAGCCGGAGAGTTTGGAAATCCCACAAACTCTAATAGCCGCCTTTCAGCTGAACACCAAATGCTCGTTCAATTGTGATATAAGATTCAAGTCGTACCAAGCATTTCGAGAACATAATCTTGAGCATCACTTAAAGACGTGTATGCAGTGTGGCTTGCACTTTGCTGAGTTCGGCATGATTCAAGACCACATAAAAACTGTTCATGTATTCGAAAACGATTGGTCcgaaatttgtaaattctgcGGTTTCCGAACCGACGATTTAGGCGAGCATATCCGACAACATAATTTCCTTTGGCTAGATGATGTCTATTGTGATAGTTGTGAGCTGCTGTTCGAGAATGAAATTGCAGTTGAAGTTCATTTTGCGGTGATCAAGCATGAATACCGGTATCGATGCTTTGTTTGTGATGAAACATTTAACGATCAAGACTCATATCGTAATCATAAATGGGGGCATACTGCGTTCACAACCATGGAACAAACTTCACCCGCACCTGACCCTCAGAACAGGGTTATAACGACCGAGATAAAGAAAGGACATCGCGCAGAACGGCTAAATCAACCAACGACATTCGAGTGCCCAATGtgtgatcaaaaatttggtcgcAAGTACAATATGGAAAAACATGTGGGTCTACATCGACACGACCATCCTTGTCGAGTGTGTGGTCTTAGTTTTGTTACGAATAACGGACTCCAAAAACATATGGGCGGTTCATGCAAATCGcgtctcaaaataaaattcgaaattgcGATTGTTTGCGGAAAGAATTCGTGCAACCAAACTTTTCGATCACGATACGACCTCTATCAGCACgagaaaaatgttcatttacaAATTCAAACCGTAAAGTGTCTAGACTGTGACCTGGAATTTAAATCAACGTCGATTATGGAGACGCATCGAAAGGTGCACTCACTCTCATTCGAGTGCCCATTATGTGACAAAAAATTCCCGCTTCTACATCAACTAAAGGCGCATGAAATTGTACATACAGATGACCGACCATTTGAATGCGATATATGCATGCAAAAATTTCGGCACCATAGCAATCTGTATCAGCACAAGTTGAGTCATGCCAATATTCGGAAATACAAGTGCCTGTATTGTGATGCCGAATTTATGCGTGCGAATACATTTCGCGAGCATATGCGAACGCACGATGGTGATCGACCGTATCAGTGCGAGATTTGCCATAAAAAGTATACGCAATCTTGCGTCCTCAGGCGGCACAAGCAATCGATGCATCGGAAGTGTGATATTTGTAAGACGGTAGTGGGGAATAAAATGAAACTTCAAGTACATATGTGGAAAATGCATCCGCTTTCGGATACAGATGGTATGGGTCAAGCAGATTATTTGGCGGAAGAGGAAGATGAATAG
Protein Sequence
MNKLTEDNALCLYKCENNDGEEEEDVDQIQDEIIEVDLYSLCRICGNMHDTLVPIYADQGLELELSTKINYYLPIDVTEEDILPLKICSNCATTVTFWHEFVAECCEADKRFSIMLQSSMIEDTKPEVAAENIQDEVNEIDNSDENQTMDTETQGTEYLEETEYENDENIPERLPVEEVELDEHSNGLESILEEDTEEQSKPNKSPDTAVTRTRCSKIISTIETSPKTSYFLNSKDSAKLDELVKKSNRSGNMRLSNEILDEIRLNLKLEEDGVYKCYECEFDTNERDVMEGHLRQHFQNTLKKLKQTMKLKAKFFDENKIEMDGKTLYECPECNKRLHATSTFLWHMRIHTGEKPYVCYMCGKKFRVYHGISRHIKETHMKTKDFACDICGRLFSNRRNVAEHRNLHSNERPYTCGTCGKSFKQQASLFMHKRLHQPHQYKCEECGLGFRIKSSLLVHATVHTGVKDHECDICQKRFRIKHELNLHKLVHTDFKPFACEKCGQSFKQKRFFVSRNATTSIQYKCKFCPMIFVEKSRFNEHTKLAHSELIFHCDMCNELVERNLLISHMTEHAVEEVRLINEQIESKKILATPDLETLRKNFQFKCDSCPKMFVTKTGLRYHVNQTHKMLRRYKCAECGKLFGCNRILRNHILSVHSNERSYNCELCPKSFKTDSSYYIHRRTHDVKIAAFPCDICGKAFNCDFDSVKEPESLEIPQTLIAAFQLNTKCSFNCDIRFKSYQAFREHNLEHHLKTCMQCGLHFAEFGMIQDHIKTVHVFENDWSEICKFCGFRTDDLGEHIRQHNFLWLDDVYCDSCELLFENEIAVEVHFAVIKHEYRYRCFVCDETFNDQDSYRNHKWGHTAFTTMEQTSPAPDPQNRVITTEIKKGHRAERLNQPTTFECPMCDQKFGRKYNMEKHVGLHRHDHPCRVCGLSFVTNNGLQKHMGGSCKSRLKIKFEIAIVCGKNSCNQTFRSRYDLYQHEKNVHLQIQTVKCLDCDLEFKSTSIMETHRKVHSLSFECPLCDKKFPLLHQLKAHEIVHTDDRPFECDICMQKFRHHSNLYQHKLSHANIRKYKCLYCDAEFMRANTFREHMRTHDGDRPYQCEICHKKYTQSCVLRRHKQSMHRKCDICKTVVGNKMKLQVHMWKMHPLSDTDGMGQADYLAEEEDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01456668;
90% Identity
iTF_01456668;
80% Identity
-