Basic Information

Insect: Tipula unca
Gene Symbol: su(Hw)
Assembly: GCA_951394425.1
Location: OX596381.1:15035715-15038014[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.029 4.3 9.4 0.2 1 21 69 89 69 90 0.93

2 13 0.06 8.9 8.4 0.3 2 23 126 148 125 148 0.92

3 13 0.13 20 7.3 2.5 1 23 154 176 154 176 0.98

4 13 4.3e-06 0.00064 21.4 3.3 1 21 182 202 182 203 0.96

5 13 1.5e-06 0.00023 22.9 0.2 2 23 216 237 215 237 0.96

6 13 1e-07 1.5e-05 26.6 1.1 1 23 247 269 247 269 0.99

7 13 5.7e-07 8.4e-05 24.2 0.5 1 23 275 297 275 297 0.98

8 13 5.3e-05 0.0078 18.0 0.6 1 23 303 325 303 325 0.99

9 13 8.6e-06 0.0013 20.5 3.3 1 23 331 353 331 353 0.96

10 13 0.00068 0.1 14.5 1.3 1 23 359 382 359 382 0.95

11 13 3.3e-05 0.0049 18.6 0.8 2 23 389 410 388 410 0.96

12 13 7.4e-06 0.0011 20.7 1.3 1 23 416 438 416 438 0.99

13 13 0.0045 0.67 11.9 3.7 2 23 445 467 444 467 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.029	4.3	9.4	0.2	1	21	69	89	69	90	0.93
2	13	0.06	8.9	8.4	0.3	2	23	126	148	125	148	0.92
3	13	0.13	20	7.3	2.5	1	23	154	176	154	176	0.98
4	13	4.3e-06	0.00064	21.4	3.3	1	21	182	202	182	203	0.96
5	13	1.5e-06	0.00023	22.9	0.2	2	23	216	237	215	237	0.96
6	13	1e-07	1.5e-05	26.6	1.1	1	23	247	269	247	269	0.99
7	13	5.7e-07	8.4e-05	24.2	0.5	1	23	275	297	275	297	0.98
8	13	5.3e-05	0.0078	18.0	0.6	1	23	303	325	303	325	0.99
9	13	8.6e-06	0.0013	20.5	3.3	1	23	331	353	331	353	0.96
10	13	0.00068	0.1	14.5	1.3	1	23	359	382	359	382	0.95
11	13	3.3e-05	0.0049	18.6	0.8	2	23	389	410	388	410	0.96
12	13	7.4e-06	0.0011	20.7	1.3	1	23	416	438	416	438	0.99
13	13	0.0045	0.67	11.9	3.7	2	23	445	467	444	467	0.94

Sequence Information

Coding Sequence: ATGGAAGGTAAAGTGACCAAagttaaaattgatgaaaatgagGAAATCGAATATATTATTTCGACGGTTAATACTTCGGACGAGGAAGAAATAATTGATGAATATATAATTGATGAAGCGGCAGAAGAAAATGAGGAGCCCGAATTGATTGAGACAGCCGATGGTCGGACACTTATCAAAATGGATCAATCGACTGTGGTGGAACATGTTTGCGGCAAGTGTGCCCAAACTTTTACAAATCTTGATATCCTTAAGAAGCATATTTCGGTATGTCGACAGAGCCaacctaaattttataatacttaTCCGAAGAAGAGAAAACTTTTATGTTTCTGTTGTGACGAGGAGAAGATCAAAGCTCATCAAGGGAATATCGTTTGTCCAGAATGCGATTTGAAATTTCATACAGCACTCGGCCGCGAGCGGCATATATTTTCTTTACACGCAGAAAATACAGaattcaaatgtaaattatgtaagtCTACCTGTCCTACAAAAGGTATACTTGATCTGCATATGCAGACACATGCTCCCACTAAGCCGTTTGAATGCGATAAATGTGGTCGAGATTTTACGCGGAAATATCATTTAGAGCGTCATTTAAAACATACCTCATGCGGTGGAACAAGCGAACAAGAGGTCTTACCGTGTGCTGTGTGcggaaaaaaatttacacgcacGGATAATTTACGTGAGCATTTACGTGGTCATATGGGCCAAACTACTAAGAAACGAGATTTCCAGTGTTCATACTGTGACAAGTCATTTTATGGTTCTTCGCTTTTAAATATTCACATTCGCACTCATACCGGGGAAAAACCGTTCCCATGCGATATATGCCAAAAACCATTTTCATCGACCGGAGCCCTTCGTAAACATCGCCGTACTCATACCGGTGAAAAACCTTATAAATGTCCAATTTGCGAATCATCGTTCAGCGCCAAGGAAACTTTTAATCGACACGTTAAAATTCATACCGGTGATCGACCACATAAATGCGAAATATGTGACAAGAGTTTTATCCAGGGTTCACAGCTTAAAGCTCACATGTTCCACCATACTGGTGAAAGTGGATTTGAATGCCGATTATGTCGACGGGTATTTAATCGAAAGGCACGGTTGCTTGACCACATGAAATTCATACATGAAGGTGAGAAACCGATCAAATGTCCATACTGTCCGAAAACTTTTTTAACGCAATCGGATTTTCGGCGGCACGAAAAAGCTCATAAAGGAGTTAAAGATTATAAGTGTGATGTGTGCCACAAGGAATTTGGAACACGGGCCATGCTGGTGACTCATTTACGTATGCACACCAATGAAGAACCGTGCATTTGCGatttatgcaataaaaaatttatccgATTTGATTGTATGCTGCGACACATTCGTGCAGTTCACCGTGAAGCGCTTTTTGAAGTAATCACCGAGGAAGAACGCAAacgcttaaaatttataaatggtaCACCGGTAGTTGCGAGTGAAGCTGAAAATAAAACTGCAATTAAAGAAGAGGAACCTAAATCGGGGGACGAAGAAATAGAAATTGATGAAAGTTATGTCGATTATgaggatgatgatgatcatgacgatgaaaatataattgatgAAGACGCAATGCATTTTGAGGAAACGACTTGCAATACGGAAGATATAAAACCATCGCTACGCGATAAACTTCCTGAGCCCGAGGAGATTACATTTATGGATGACGCTacgttaaaaaaatcaatttcacaaCTATTAAATTTGCTCGTCGATGAGGAAACACTTTTGCAGTTTGGTTGGCCCGAGACCGGGGTAGAAGAAGTATTGAGTTCGGTGATTAAGCAGTGCGGACATCAGCCCGCAGATTATAAAGATTGTGGCGATTATACGACAAAAATGCGTGAAAATACAAAACTTCTGTTCACCGTGGTAATTGATGATGACTCGATCAAGTCGCTACTAAACAATCACACAATTGACGAAGTCATATTGCGGGTCCTTAAAATGGCCCAGAATAAGTGA
Protein Sequence: MEGKVTKVKIDENEEIEYIISTVNTSDEEEIIDEYIIDEAAEENEEPELIETADGRTLIKMDQSTVVEHVCGKCAQTFTNLDILKKHISVCRQSQPKFYNTYPKKRKLLCFCCDEEKIKAHQGNIVCPECDLKFHTALGRERHIFSLHAENTEFKCKLCKSTCPTKGILDLHMQTHAPTKPFECDKCGRDFTRKYHLERHLKHTSCGGTSEQEVLPCAVCGKKFTRTDNLREHLRGHMGQTTKKRDFQCSYCDKSFYGSSLLNIHIRTHTGEKPFPCDICQKPFSSTGALRKHRRTHTGEKPYKCPICESSFSAKETFNRHVKIHTGDRPHKCEICDKSFIQGSQLKAHMFHHTGESGFECRLCRRVFNRKARLLDHMKFIHEGEKPIKCPYCPKTFLTQSDFRRHEKAHKGVKDYKCDVCHKEFGTRAMLVTHLRMHTNEEPCICDLCNKKFIRFDCMLRHIRAVHREALFEVITEEERKRLKFINGTPVVASEAENKTAIKEEEPKSGDEEIEIDESYVDYEDDDDHDDENIIDEDAMHFEETTCNTEDIKPSLRDKLPEPEEITFMDDATLKKSISQLLNLLVDEETLLQFGWPETGVEEVLSSVIKQCGHQPADYKDCGDYTTKMRENTKLLFTVVIDDDSIKSLLNNHTIDEVILRVLKMAQNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01457751; iTF_01460482; iTF_01456669; iTF_01455071;
90% Identity: -
80% Identity: -