Basic Information

Insect: Tipula unca
Gene Symbol: ZFX
Assembly: GCA_951394425.1
Location: OX596381.1:199633542-199636833[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 6.8e-06 0.001 20.8 0.3 2 23 156 177 156 177 0.97

2 14 5.5e-07 8.2e-05 24.2 4.0 1 23 183 205 183 205 0.98

3 14 7.7e-06 0.0011 20.6 1.0 1 23 211 233 211 233 0.97

4 14 0.00011 0.016 17.0 4.6 1 23 241 263 241 263 0.97

5 14 1.6e-05 0.0024 19.6 6.6 1 23 269 292 269 292 0.98

6 14 1.3e-07 1.9e-05 26.3 0.7 1 23 298 320 298 320 0.97

7 14 0.00014 0.02 16.7 1.0 1 23 326 348 326 348 0.98

8 14 8.8e-07 0.00013 23.6 0.7 2 23 492 513 491 513 0.97

9 14 1.1e-06 0.00016 23.4 1.2 1 23 519 541 519 541 0.98

10 14 8.9e-05 0.013 17.3 3.9 1 23 547 569 547 569 0.97

11 14 0.017 2.5 10.2 3.9 1 23 577 599 577 599 0.97

12 14 2.1e-07 3.1e-05 25.6 1.9 1 23 605 628 605 628 0.98

13 14 6.1e-07 9e-05 24.1 1.0 1 23 634 656 634 656 0.96

14 14 0.0012 0.18 13.7 2.7 1 23 662 684 662 684 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	6.8e-06	0.001	20.8	0.3	2	23	156	177	156	177	0.97
2	14	5.5e-07	8.2e-05	24.2	4.0	1	23	183	205	183	205	0.98
3	14	7.7e-06	0.0011	20.6	1.0	1	23	211	233	211	233	0.97
4	14	0.00011	0.016	17.0	4.6	1	23	241	263	241	263	0.97
5	14	1.6e-05	0.0024	19.6	6.6	1	23	269	292	269	292	0.98
6	14	1.3e-07	1.9e-05	26.3	0.7	1	23	298	320	298	320	0.97
7	14	0.00014	0.02	16.7	1.0	1	23	326	348	326	348	0.98
8	14	8.8e-07	0.00013	23.6	0.7	2	23	492	513	491	513	0.97
9	14	1.1e-06	0.00016	23.4	1.2	1	23	519	541	519	541	0.98
10	14	8.9e-05	0.013	17.3	3.9	1	23	547	569	547	569	0.97
11	14	0.017	2.5	10.2	3.9	1	23	577	599	577	599	0.97
12	14	2.1e-07	3.1e-05	25.6	1.9	1	23	605	628	605	628	0.98
13	14	6.1e-07	9e-05	24.1	1.0	1	23	634	656	634	656	0.96
14	14	0.0012	0.18	13.7	2.7	1	23	662	684	662	684	0.98

Sequence Information

Coding Sequence: atgaaaccaattttttttgatGCAAATTTACCACAATATTTATGTGATAACTGTAAACTGCGGCTCGAAAATGCGTATATATTTCGTAAGGAGATTGAATACTCTGAAAGTAAATTACGCGAATTGTTTCCATATGAGGAATCCCAGAAAAAGGAGGAGGTTGTGGATGAAATTAAAAGTGAGGAGGTGGTAGCTGAAGAAATACCAGTACAGGTCGATATCCATGTACAAGATGAGTTGATCAAAGAAGAGGAGGAATCTGGCGAAGGGAAAGAGAATGATGAGGATGGAAATTCATTTGCTGGTGGTGAAGATGGCCATGAATCGGGGATTTCGTACATTGCAGAGGATACTAAGCCAAAGGTTAAGAAAAAAACGCGTATTAAAAGCGGAGCtagacacaaaattttaaaagaggtTCGAATGAAAGCTGCTAAGGTAACTATAAATGCCGAGGAGAATCGAACGTGTAAGCAGTGCGGCAAGGTATTTGCCCGCTATCAAAATCTGGTGATCCACGAAAGGATCCATACAGGGGAAAAGCCGTTCGAATGCCATTTGTGTGATAAGAAATTTACCCAAAAATCTAATCTGTTCTTGCACCTCAAAATTCATTCACAGGAAAAGTCGTTTATCTGCGAAATATGTAGCAAGCAATTTACCACAAATCTGCAGCTAAAACAGCATATGGTTACGCATCTGCCCGAATCGGCGAAACAGTTCAAATGTGATACATGCCCGAAAGCTTTTCATGACAAACGCACACTGAAACGGCATCATGCTATTCACGAGGGTAAAAAAAGCTTCAAATGCACGCACTGCCAAAAAGGCTTCATAACACGATGTTACCTAAACAAACATATCCGAACGGTTCATCTATCGATAAAACGACATGTTTGCACTGTCTGTGGCAAAGCATTTTCGAATTCGGGTAACTTACGTGCCCATTTTCGAATACACACTGGCGAGAAACCCTACGAATGTAAATACTGTGATGCCAAATTTAACCAATCGACCCCACTGGTGCGCCACACGCAGCAGCATATTGATCGAGGGGATATATATGAGAATGTCGAGCTTCCacaatttttgtgtaataaCTGTGCAAATCGacttgaaaatgtatatttaatgaaattacaaGTGGAAGAGACGGACGATAGGCTGAAAAAAATCTGTAGCAATTTGACAACAAaggaaatatttgaaccacccCCTGTAGAGCCTCCACCATCCGAAATTGACCTTAATGCAGTAATCGCGAACGTGGTAGACGATAGCGTGGAACCGATTAAAATTGAGGAGGGGCCCAGTTTAGAATTTGCCAATGTTTCGGATTTTGATCGAGTATATGTGAAGGAGGAAGATGGGAATTATGATGATAGCTCGAGCGATGTAAAGGATATAAAAGATGAGGATGAAGATAGGACGAGTGATGAAAAACGGAGTAAAATTAGAAGTAAGACAAATAAAACATGTGAAATATGTGGTAAAGGATTTACACGAACTGAAACTCTCAAAATTCATCAACGGGTGCACACAGGTGAAAAACCATTCGaatgtaatatatgtaataaaaaatttgcccAAAAATCGAGCGTATTCGCTCATCTTAAAACTCATTCCGACGAAAAGGCCTTCATATGCGAAGTATGCAGCAAACAGTTTAAGACCAAGCTTCATTTAAAGCAACACCTGACCACACATCTACCCGAATCGGAAAAACGTTTTAAATGTGACCAATGCCCTAGGGCATTTCACGTTGAACATCATCTCAAAGGACATAAAGCGATACACGAAGGTAAAAAACCGTACAAGTGTAACGATTGTGATAAAGGTTTTATATCGCGACGTTATTTAAATCGACACTATCGTACCGTGCATTTATCAATTAAGCGACACGCGTGTACCGTGTGtggaaaaacattttcaaattccgGCAATTTAGCATCTCATTTCCGAATACACACGGGTGAAAAACCGTACGAGTGTAACTACTGTGATTCGAGGTTTAACCAATCGACCCCGCTAGTGCGACATACTCAGCATCATATAAACAGGGGTGATCCGGTCAAGATAGAAGCTTTATGA
Protein Sequence: MKPIFFDANLPQYLCDNCKLRLENAYIFRKEIEYSESKLRELFPYEESQKKEEVVDEIKSEEVVAEEIPVQVDIHVQDELIKEEEESGEGKENDEDGNSFAGGEDGHESGISYIAEDTKPKVKKKTRIKSGARHKILKEVRMKAAKVTINAEENRTCKQCGKVFARYQNLVIHERIHTGEKPFECHLCDKKFTQKSNLFLHLKIHSQEKSFICEICSKQFTTNLQLKQHMVTHLPESAKQFKCDTCPKAFHDKRTLKRHHAIHEGKKSFKCTHCQKGFITRCYLNKHIRTVHLSIKRHVCTVCGKAFSNSGNLRAHFRIHTGEKPYECKYCDAKFNQSTPLVRHTQQHIDRGDIYENVELPQFLCNNCANRLENVYLMKLQVEETDDRLKKICSNLTTKEIFEPPPVEPPPSEIDLNAVIANVVDDSVEPIKIEEGPSLEFANVSDFDRVYVKEEDGNYDDSSSDVKDIKDEDEDRTSDEKRSKIRSKTNKTCEICGKGFTRTETLKIHQRVHTGEKPFECNICNKKFAQKSSVFAHLKTHSDEKAFICEVCSKQFKTKLHLKQHLTTHLPESEKRFKCDQCPRAFHVEHHLKGHKAIHEGKKPYKCNDCDKGFISRRYLNRHYRTVHLSIKRHACTVCGKTFSNSGNLASHFRIHTGEKPYECNYCDSRFNQSTPLVRHTQHHINRGDPVKIEAL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01457743;
90% Identity: -
80% Identity: -