Basic Information

Insect: Tipula lateralis
Gene Symbol: ZFX
Assembly: GCA_963932295.1
Location: OZ010736.1:116077798-116080787[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 6.5e-06 0.00084 20.7 0.3 2 23 197 218 197 218 0.97

2 14 5.2e-07 6.8e-05 24.2 4.0 1 23 224 246 224 246 0.98

3 14 1.3e-05 0.0017 19.8 1.0 1 23 252 274 252 274 0.97

4 14 0.0001 0.013 17.0 4.6 1 23 282 304 282 304 0.97

5 14 8.9e-05 0.012 17.2 6.2 1 23 310 333 310 333 0.98

6 14 1.2e-07 1.6e-05 26.2 0.7 1 23 339 361 339 361 0.97

7 14 0.07 9.1 8.0 0.3 1 14 367 380 367 383 0.88

8 14 8.4e-07 0.00011 23.5 0.7 2 23 524 545 523 545 0.97

9 14 1e-06 0.00013 23.3 1.2 1 23 551 573 551 573 0.98

10 14 8.4e-05 0.011 17.2 3.9 1 23 579 601 579 601 0.97

11 14 0.016 2 10.1 3.9 1 23 609 631 609 631 0.97

12 14 4.1e-07 5.4e-05 24.5 1.9 1 23 637 660 637 660 0.98

13 14 1.3e-06 0.00017 22.9 0.3 3 23 668 688 667 688 0.99

14 14 0.00026 0.033 15.7 1.9 1 23 694 716 694 716 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	6.5e-06	0.00084	20.7	0.3	2	23	197	218	197	218	0.97
2	14	5.2e-07	6.8e-05	24.2	4.0	1	23	224	246	224	246	0.98
3	14	1.3e-05	0.0017	19.8	1.0	1	23	252	274	252	274	0.97
4	14	0.0001	0.013	17.0	4.6	1	23	282	304	282	304	0.97
5	14	8.9e-05	0.012	17.2	6.2	1	23	310	333	310	333	0.98
6	14	1.2e-07	1.6e-05	26.2	0.7	1	23	339	361	339	361	0.97
7	14	0.07	9.1	8.0	0.3	1	14	367	380	367	383	0.88
8	14	8.4e-07	0.00011	23.5	0.7	2	23	524	545	523	545	0.97
9	14	1e-06	0.00013	23.3	1.2	1	23	551	573	551	573	0.98
10	14	8.4e-05	0.011	17.2	3.9	1	23	579	601	579	601	0.97
11	14	0.016	2	10.1	3.9	1	23	609	631	609	631	0.97
12	14	4.1e-07	5.4e-05	24.5	1.9	1	23	637	660	637	660	0.98
13	14	1.3e-06	0.00017	22.9	0.3	3	23	668	688	667	688	0.99
14	14	0.00026	0.033	15.7	1.9	1	23	694	716	694	716	0.98

Sequence Information

Coding Sequence: atgaatacAATATCGATAAATTCATGTCGTATCTGCTTATTCAAACCCGGAACTACATCTTTATGTGATAATCGAAGTGATACAACCTTAATCgatatgatgaaaatattttcaaatctgAATattcttttcgattcaaatttacctcaatatttatgtgataattgTAAATTGCGACTGGAAAATGCATATTTATTTCGTAAAGAGATTGAATATTCGGAAAGTAAATTGCGCGAATTATTTCCTTATGGTGAACCCCAGAAGAAAGAAGAGGCGGTGAATTCTGATGAGATTAAAAGTGAAGATACATTAACTGAAGTGATCCCTCCAATGTTGTTAGACTTACAAGTAGAAGAAGAAATGATAAAAGAAGAGGAAGAACCAGGCGAAGGTAAAGAAAATGATGATGGTAATTCTTTTGCTAGCGATGATCATCCAGATGACGATTTAAGAACTTCATATTCCGTAGACGATACTAAGCGCAAGGTTAAGAAAAAGTCTCGTATAAAAAACGAAACAAGAAACAAGATTTTAAAGGAAGTACGCATGAAAGCGTCTAAATCGATTATAAATACTGAAGAGAGTAGAACGTGCAAACAGTGTGGTAAAGTATTTGCCCGTtatcaaaatttagttataCACGAAAGGATTCATACGGGTGAAAAGCCGTTCGAGTGTCATTTGTGcgataaaaaatttactcaaaAGTCAAATCTTTTCTTACATCTTAAAATCCATTCACAAGAGAAGTCATTCATATGTGAAGTATGTAGCAAACAATTTACAACAAATCTGCAGCTAAAACAGCACATGGTCACACATCTGCCCGAATCGGCAAAACAGTTTAAATGTGATACATGCCCAAAAGCTTTCCACGACAAACGTACATTGAAGCGACACCATGCTATCCACGAGGGtatgaaatgttttaaatgtACACATTGTCTTAAAGGGTTCATAACACGATGCTATTTAAACAAGCATATACGAACAGTCCATCTATCAATAAAACGACACGTTTGCACCGTGTGTGGTAAAGCGTTTTCGAATTCAGGCAATTTGCGAGCCCATTTTAGGATTCACACGGGTGAAAAACCATACGAATGCAAATACTGTGATGCTAAATTTAATCAATCAACCCCATTGGTCTACGAGAATGGCGAATTACCTAAATTTTTGTGTAATAACTGTGCGAATCGTCtcgaaaatgtatatttaatgaaattgcaAGTGGAGGAGACTGACGATAGGCTGAAGAAAATTTTGTGTGCCAATATTACAACAAAGGAAATTTTTGAACCTCCCCCTGAAGAGCCTTTACCTCCCGAGATTGATCTTAATGTTGTGATCAGTGATGTGGTGGACGAACATGAGGAAGCAATCAAAATGGAAGATACGCCCAATTTAGAGTTTGCCAATGTTTCGGATTTTGATCGCGTCTACGTGAAGGAGGAAGACGGAAATTTTGGCCTAGATGAAAGCTCAAGCGACGTAAAAGATATAAAAGATGAGGATGATGTAAGAATAGACGAAGATAAATGTaggaaaattagaaataaaacgaataaaacatgCGAAATATGTGGTAAAGGTTTTACACGAACCGAGACTCTAAAAATCCATCAGCGGGTACACACAGGCGAAAAACCATTCGAGtgcaatatatgtaataaaaaatttgccCAAAAATCAAGCGTTTTCGCCCATCTCAAAACGCATTCCGACGAGAAGGCTTTTATTTGCGAAGTGTGTAGCAAACAGTTCAAGACAAAGCTTCACTTAAAACAACACCTAACTACACATCTACCTGAATCGGAAAAACGTTTTAAATGTGATCAGTGTCCTCGTGCATTCCATGTCGAACATCATCTCAAAGGGCATAAAGCGATACACGAAGGTAAAAAACCATACAAGTGTTCAGAGTGTGACAAAGGATTTATATCACGGCGCTATTTGAATCGACACTATCGTACCGTACATTTATCAATCAAGCGTCATGGATGCACCGTATGCGGCAAAACATTTTCGAATTCCGGCAATTTAGCATCCCATTTTCGGATACATACAGGAGAAAAACCGTACGAGTGTAACTATTGTGATGCAAGATTTAATCAATCGACTCCATTAGTGCGACATACTCAGCACCACATAAATCGAGGGGATCTAGTTAAAATCGAACCATCATGA
Protein Sequence: MNTISINSCRICLFKPGTTSLCDNRSDTTLIDMMKIFSNLNILFDSNLPQYLCDNCKLRLENAYLFRKEIEYSESKLRELFPYGEPQKKEEAVNSDEIKSEDTLTEVIPPMLLDLQVEEEMIKEEEEPGEGKENDDGNSFASDDHPDDDLRTSYSVDDTKRKVKKKSRIKNETRNKILKEVRMKASKSIINTEESRTCKQCGKVFARYQNLVIHERIHTGEKPFECHLCDKKFTQKSNLFLHLKIHSQEKSFICEVCSKQFTTNLQLKQHMVTHLPESAKQFKCDTCPKAFHDKRTLKRHHAIHEGMKCFKCTHCLKGFITRCYLNKHIRTVHLSIKRHVCTVCGKAFSNSGNLRAHFRIHTGEKPYECKYCDAKFNQSTPLVYENGELPKFLCNNCANRLENVYLMKLQVEETDDRLKKILCANITTKEIFEPPPEEPLPPEIDLNVVISDVVDEHEEAIKMEDTPNLEFANVSDFDRVYVKEEDGNFGLDESSSDVKDIKDEDDVRIDEDKCRKIRNKTNKTCEICGKGFTRTETLKIHQRVHTGEKPFECNICNKKFAQKSSVFAHLKTHSDEKAFICEVCSKQFKTKLHLKQHLTTHLPESEKRFKCDQCPRAFHVEHHLKGHKAIHEGKKPYKCSECDKGFISRRYLNRHYRTVHLSIKRHGCTVCGKTFSNSGNLASHFRIHTGEKPYECNYCDARFNQSTPLVRHTQHHINRGDLVKIEPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01458835;
90% Identity: -
80% Identity: -