Tunc031375.1
Basic Information
- Insect
- Tipula unca
- Gene Symbol
- btbd6
- Assembly
- GCA_951394425.1
- Location
- OX596382.1:13019528-13032242[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 5 1.8e-05 0.0031 19.1 0.0 9 57 12 56 6 60 0.85 2 5 6.9e-17 1.2e-14 55.8 0.8 10 108 60 154 56 156 0.94 3 5 2e-16 3.5e-14 54.3 0.8 4 103 173 268 171 274 0.91 4 5 1.7e-18 2.9e-16 61.0 0.5 3 105 489 587 488 590 0.94 5 5 1.7e-17 3e-15 57.8 2.8 4 105 608 705 606 710 0.92
Sequence Information
- Coding Sequence
- ATGGAAATACCAAGCAAACTTTTAGGTTTAGCATTCCTGTCAGATGTTATATTTATCGTCGGCGATAAGCGAATCTATGCTCATTCTTTAGAGTTAATGAAGCGAAGCATTGTGTTTCAACAGCAGCTGGAATCAAATATAGGTGGACAAAAAGAAATTCCTATTACTGATTATGGAATATCGGATGTCACGTTCTCCGTGGAAGACAAACCGATTTATGCTCACTCGTTAGAGTTAATGAAGCGGAGTATCGTGTATAAACAGCAGTTGGAGTCGACTTTgggtgaaaaaaaattaattgcaattagTGATGTTAGATATGACGACTTTTATCAGTTCATTCGATTTATTTACACCGACGAGTGTAAGATCAATGAagaaaattctttaatattattgaaattggcGAAAGAGTACAAAGTGATGGGATTAGTCAACGCTGTGcacaatttcaacaaaaatatggAATTCGAAATCAACCATGCAGCATTCAAAATGAAGGAAATGTCGTGCAAACTTTTTAATGTACAATTCCTATCGGATGTTATATTTATCGTCGATGACAAGCAGATTTATGCTCACTCGTTGGAGTTAATGAAGCGTAGCGTTGTATTTCAACAGCAGTTGACGTCACCTGTTGGTGAGAAAAAGCAAATTCCAATTAATGGATATGGTTATGATACATTTTATCAgtttattcgatttatttacaCTGACCAGTGTGATATCACtacagaaaattgttttgaattgttGAAATTGGCAATAGTGTATAAAGTGGTAAGGCTCATCAATTTTGTGCAAAGTTCGTATGATTATGACAATTTCGAATTGTTAGACTTTTGTGTTGTAGCAAGGGACCAAATTGCTTTACATGATGCTAAACGTAAAGTAGCTAAGGATTTAAAAAGATTAATGACTGCAGATTCATTTATATCGATACGTCCCGATACGATTGaagaaatcttaaaaattgatCATGTCGACGATGGATTATCCGAATTAAATATCATCGATGCACTTGTCGGTTGGTTCAATCACTATTGCATTCAAAACAATATGCAATTTTCCGAGTGCCTTctaaaatttgggaaatttattcGATTAATTCGTTTCCCAACGATGTCCAGCGAAGAGATGGATGATATTAAAACAAGATATCCACATTTATTAACGCAAAGTGATATACTGCTCATTGAGGGTCAGAAAATATTTGGAGCTGACTTTGGAAGCGGAATATTTAATTGTACGCCACGCTTGAATTTGATGCGATATTTATACACGGAGGTATACACGAAACAATTCTTTGATTaccaatttaaaaccaaatttgtcGTCGCTTCTGACATGATCCTCGGTGGATTTGCTATTGGCTTGGCTACACCTTTAAAAtcaaatttaatttcgtcgaAAATGGAATTTGAAATCAATCAAGTGCCATTCGAAATGGTCGAAATATCGGCCAAGCTATTCAATTCAGAATCGCTATCGGATATCACGTTCTCAGTGGAAGACAAACCGATTTATGCTCACTCGTTAGAGTTAATGAAGCGAAGCGCTGTGTTTATACAGAAGTTGGAGACAAATTTgggtgaaaaaaaattaattccaattaGTGATTTTGGGTATGACGACTTTTATCAGTTCATCCGATTTATTTACACCGACGAGTGTAACATCAATGAagaaaattctttaatattattgaaattggcGAAAGAGTACAAAGTGATGGGATTAGTCAACTCTGTGCACAATTTCAAAGATATGGAATTTGAAATCAATCATGCGGCACtcaaaatgaaagaaatatCTAGCGAACTTTTAGATTTTAAGTTCCTATCGGATGTTACATTTGTCGTCGAAGACAAACATATTCATGCTCACTCTTTGGAGTTAATGAAGCGTAGTGTTGTATTTCAACAGCAGCTAGAGCTAACGATCggtgaaaaaaaacaaattttaattactgaaTATGGATATGAAACATTTTACCAGTTCATACGATTTATATACACTGACCAGTTTGATATCagtaaagaaaattgttttgaattgttGAAATTGGCAATAGTATATAAAGTGGTAAGGCTTGTCAATGTTGTGCAAAATTCATATGATTATGATAATTTCCAATTGTTAAACTTTTGTGTTGCGGCAAAGGACCAAATTGCTTTACACAATGCTAAACGTAGAGTAGCAGCTTTCAATTTAAAAGAGTTAATGGCTGCAGAGacatttatatcaattcattCCGATACgattgaagaaattttaaaagctgaCCAGGTCGGCGCTGGAATATCTGAATTAAATATCTTGGATGCATTGGTCCGTTGGTTGAACCACCATTGCATTCAAAACAATATGCAATTTTCCGAGTGCCgtcaaaaattcgataaattagtTCGATTAATTCGATTTCCAACGCTGTCGAAGAAGGAAATGAGAGATATTGAAACAAGATATCCCCATTTATTAACGGAAAGTGATATCCTGCTGATTGAGGGCCACAAAATATTCGGAGCTAATTTTGAAAGCGGAATATTTAATTGTACACCACGGTTGAATTTTGTGCCATATAAATCTACAAAAGTACTAACTAACGAATTTGTAACCAATTTTTTCGTCACTTCTGACATGATCCTCGGTGGATTTTCTTTTGGCTTGGCTTCTATGTATGGCTACAATAATTATACCGGTTTCGTTTTGGCCGATGCAAATCTTGAGGCAATTTCAGAACCGCTGAATAAGACGTGA
- Protein Sequence
- MEIPSKLLGLAFLSDVIFIVGDKRIYAHSLELMKRSIVFQQQLESNIGGQKEIPITDYGISDVTFSVEDKPIYAHSLELMKRSIVYKQQLESTLGEKKLIAISDVRYDDFYQFIRFIYTDECKINEENSLILLKLAKEYKVMGLVNAVHNFNKNMEFEINHAAFKMKEMSCKLFNVQFLSDVIFIVDDKQIYAHSLELMKRSVVFQQQLTSPVGEKKQIPINGYGYDTFYQFIRFIYTDQCDITTENCFELLKLAIVYKVVRLINFVQSSYDYDNFELLDFCVVARDQIALHDAKRKVAKDLKRLMTADSFISIRPDTIEEILKIDHVDDGLSELNIIDALVGWFNHYCIQNNMQFSECLLKFGKFIRLIRFPTMSSEEMDDIKTRYPHLLTQSDILLIEGQKIFGADFGSGIFNCTPRLNLMRYLYTEVYTKQFFDYQFKTKFVVASDMILGGFAIGLATPLKSNLISSKMEFEINQVPFEMVEISAKLFNSESLSDITFSVEDKPIYAHSLELMKRSAVFIQKLETNLGEKKLIPISDFGYDDFYQFIRFIYTDECNINEENSLILLKLAKEYKVMGLVNSVHNFKDMEFEINHAALKMKEISSELLDFKFLSDVTFVVEDKHIHAHSLELMKRSVVFQQQLELTIGEKKQILITEYGYETFYQFIRFIYTDQFDISKENCFELLKLAIVYKVVRLVNVVQNSYDYDNFQLLNFCVAAKDQIALHNAKRRVAAFNLKELMAAETFISIHSDTIEEILKADQVGAGISELNILDALVRWLNHHCIQNNMQFSECRQKFDKLVRLIRFPTLSKKEMRDIETRYPHLLTESDILLIEGHKIFGANFESGIFNCTPRLNFVPYKSTKVLTNEFVTNFFVTSDMILGGFSFGLASMYGYNNYTGFVLADANLEAISEPLNKT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -