Tlat007649.2
Basic Information
- Insect
- Tipula lateralis
- Gene Symbol
- Hr39
- Assembly
- GCA_963932295.1
- Location
- OZ010736.1:98558686-98562880[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.086 1.1e+03 -0.2 1.7 66 175 96 201 72 227 0.55 2 4 3 3.9e+04 -8.7 12.8 51 132 166 276 129 326 0.41 3 4 3.1e-09 4e-05 24.3 0.0 1 31 426 456 426 470 0.84 4 4 6.7e-77 8.8e-73 247.2 4.1 154 408 480 743 469 743 0.89
Sequence Information
- Coding Sequence
- ATGGCCACTACGGGTAGTAGCAGTAGTAGTGGTGGCAGTAATAACTGCGTCGCTAGCAGTGGTTGTCCTCCTATTTCGCGAGGTAACGTGTCCGTAACAAGTATTAATTGCAGTGATGATAATGGAACACAGTCCCAGATTACTCAGGCAAATGGAACAATATTAACAAATGGTGGGACAActcatttttttgaaaatggtgGAATTAGAATTTCtgtgccaaaaatggaagaatcAGATGAATCTGATACCGAATTGACAAATATTGAGAATAATTCAAATAGCAATGTTGGAATGCGAgaaaatcgtaataaaaatatGCCTCGACCGATGAGTTGGGAGGGTGAACTATCGGAAAATGAGGATAGCAATATGATGGTTGTAGAAAATGGTGAAGCGAGTAATTTATCTGCCGCCACAATTCAAACAACGTCAACAACTGCAGTTACAACTGACGAACCAATTAATTTACAACAATTGCCAAAAGAATTTAAGCCTGAATTTTTAGACACCAATAGCTCATCGAATTTAACAGCAACCTCGTCAACTGCaacaacatatttaaatttaaatagtaaaaaatttccggagtatattaatttaaaaaatgaaactgGTGTTCATGATGTAATTAGTTCTCCATTACTAGCTAGATCTAAATCAAATTTACTTCCAGCCAATCCAAGTCCGGATTCCGCAATACATTCTGTTTACACACATAGTTCACCTTCTCAATCACCATTAACATCTCGACATACTCCGTACACTCCATCGCTGAGTCGAAATAATAGTGATGCGTCACATAGTAGTTGTTATTCATATAGTTCCGAATTTAGTCCAACACATTCCCCCATACAAAGCCGTCACTATTTATATGGACCGCCACCAAATGCTGCCCAAGCTGGTCTGACAAATTCACCTGCACATCATTCACTGCTATACCGTCCGATGTTAGATAATGAACAAAGTACATCATCGAAATTTTTACAACCAAAAGAAGAAGGTGTATTAGAAGGCGAGGCAATTCCTTCGCCAGGAATATCACGGCAACAACTAATAAATAGTCCGTGTCCaatatgtggtgataaaatatcTGGTTTCCATTATGGTATTTTTTCGTGTGAATCGTGCAAAGGGTTTTTTAAGCGTACTgttcaaaatagaaaaaattatgtatgtttgCGAGGGGCAGCATGTCCTGTTACAATAGCAACACGAAAGAAATGTCCGGCATGCcgatttgaaaaatgtttgcaAAAGGGTATGAAATTAGAAGCGATCCGTGAAGATCGGACACGTGGTGGACGATCCACCTACCAATGTTCATATACATTACCCGGATCAATGTTAAGTCCATCGGTTAGTTCCGAATCATCAGCTAATATGTATTATAGTCAAAGACTTTCCACTAATGGATTATTAAAAGTTGAAACACCTGAATCGAGTTCAAGTACATCGACATTTAATAGTAGTGTTAAACTAGAAATTCCACCACTTTTGCAAGACATTATGGATGTTGAACATTTGTGGCATTACAATGATGCTGAGTTGTCTCGTCTAAATCAACCAGCTCCGTCGAATCAATCAACAAATGTTGCATCGAATCCTTTATTAGCTAGTGCCGGATTATCAAAAAGTGATAATCCTGATTTAATTGCAAATTTATGTAATGTAGCTGATCATCGATTGTATAAAATAGTGAAATGGTGTAAAAGTTTACccctatttaaaaatatatcgattGATGATCAAATATGTTTACTTATAAATTCATGgtgtgaattattattattttcatgttgTTTTCGATCAATGTCCACTCCTGGTGAGATTAGAATATCGTTAGGCAAATCGATTACATTACAACAAGCAAGATCAAGTGGTTTACAGtcaTGTATTGAACGTATGCTTAATTTAACAGAGCATCTAAGGCGATTAAAGGTAGATAGATATGAGTATGTTGCTATGAAAGTTATAGTATTACTACAATCAGACACATCCGAATTAAAGGAGCCTGAAAAAGTGCGAACAAGTCAGGAGAAGGCATTACAAGCATTACAGGCTTATACATTATCACATTATCCGGATACACCGGCTAAATTTGGTGAACTGTTATTACGGATACCCGAGTTACAGCGAACATGCCAGGTTGGAAAAGACATGctaattattaaatcaaaagaaGGCGAAGAATTTAATTTACTGATGGAATTACTACGAGGTGAACACTAG
- Protein Sequence
- MATTGSSSSSGGSNNCVASSGCPPISRGNVSVTSINCSDDNGTQSQITQANGTILTNGGTTHFFENGGIRISVPKMEESDESDTELTNIENNSNSNVGMRENRNKNMPRPMSWEGELSENEDSNMMVVENGEASNLSAATIQTTSTTAVTTDEPINLQQLPKEFKPEFLDTNSSSNLTATSSTATTYLNLNSKKFPEYINLKNETGVHDVISSPLLARSKSNLLPANPSPDSAIHSVYTHSSPSQSPLTSRHTPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQSRHYLYGPPPNAAQAGLTNSPAHHSLLYRPMLDNEQSTSSKFLQPKEEGVLEGEAIPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTIATRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPGSMLSPSVSSESSANMYYSQRLSTNGLLKVETPESSSSTSTFNSSVKLEIPPLLQDIMDVEHLWHYNDAELSRLNQPAPSNQSTNVASNPLLASAGLSKSDNPDLIANLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRISLGKSITLQQARSSGLQSCIERMLNLTEHLRRLKVDRYEYVAMKVIVLLQSDTSELKEPEKVRTSQEKALQALQAYTLSHYPDTPAKFGELLLRIPELQRTCQVGKDMLIIKSKEGEEFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01458497;
- 90% Identity
- iTF_01458497;
- 80% Identity
- iTF_01457384; iTF_01457469;