Basic Information

Insect: Tipula helvola
Gene Symbol: RREB1
Assembly: GCA_963556165.1
Location: OY744483.1:335380559-335385823[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00093 0.35 14.2 2.2 1 23 131 153 131 153 0.97

2 14 0.00013 0.049 16.9 5.1 1 23 161 183 161 183 0.99

3 14 5.3 2e+03 2.4 0.7 1 23 300 324 300 324 0.82

4 14 0.02 7.6 10.0 4.2 2 22 330 350 330 350 0.94

5 14 3.5 1.3e+03 3.0 0.6 1 11 395 405 395 415 0.85

6 14 0.03 11 9.5 0.1 1 23 552 574 552 574 0.97

7 14 4e-05 0.015 18.5 0.9 1 23 583 605 583 605 0.99

8 14 0.001 0.39 14.1 2.0 1 23 611 634 611 634 0.97

9 14 0.0012 0.44 13.9 2.1 1 23 980 1003 980 1003 0.95

10 14 2.6e-05 0.0096 19.1 0.4 2 23 1312 1333 1311 1333 0.98

11 14 0.18 68 7.0 6.3 1 23 1339 1362 1339 1362 0.97

12 14 0.66 2.5e+02 5.3 3.8 1 23 1444 1467 1444 1467 0.95

13 14 0.011 3.9 10.9 0.5 3 23 1522 1542 1520 1542 0.96

14 14 0.0056 2.1 11.8 5.1 1 23 1548 1570 1548 1570 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00093	0.35	14.2	2.2	1	23	131	153	131	153	0.97
2	14	0.00013	0.049	16.9	5.1	1	23	161	183	161	183	0.99
3	14	5.3	2e+03	2.4	0.7	1	23	300	324	300	324	0.82
4	14	0.02	7.6	10.0	4.2	2	22	330	350	330	350	0.94
5	14	3.5	1.3e+03	3.0	0.6	1	11	395	405	395	415	0.85
6	14	0.03	11	9.5	0.1	1	23	552	574	552	574	0.97
7	14	4e-05	0.015	18.5	0.9	1	23	583	605	583	605	0.99
8	14	0.001	0.39	14.1	2.0	1	23	611	634	611	634	0.97
9	14	0.0012	0.44	13.9	2.1	1	23	980	1003	980	1003	0.95
10	14	2.6e-05	0.0096	19.1	0.4	2	23	1312	1333	1311	1333	0.98
11	14	0.18	68	7.0	6.3	1	23	1339	1362	1339	1362	0.97
12	14	0.66	2.5e+02	5.3	3.8	1	23	1444	1467	1444	1467	0.95
13	14	0.011	3.9	10.9	0.5	3	23	1522	1542	1520	1542	0.96
14	14	0.0056	2.1	11.8	5.1	1	23	1548	1570	1548	1570	0.99

Sequence Information

Coding Sequence: ATGGATCGTCGCATATCAACCAATTCCGAATCATCGATTGAACCGATGGACGTAAGTGtttcgaataaaacaacaagttcAGACGGTACAAATAATACATCGTCTGCAATGGCAATAAGTAAAATAAGTGAACCAAATCATAGTGAATCGGATAACGGTGGTATTGAATCGgaggaaaatgatgaaaatattgTAAGACGTGAAAATTTGCGTTTGCACAATAGTAGTAGCCACATTGATACAAAAATGCTGCGAAAAAAATTTCGTCtcatgaataataataataataccaacaataacaacaacaataataataataataatagtagtaatAATACGGCGGCGACCGATAAAAATCTCAGTATTGAATCAcatggaaatttggaaaattttcaatgTCATATTTGCTCAAAACATTTAACAACATCGATCGCATTGGTCCGCCATCTGCAAGCGCATAGCTTAGAGAGTGAAAGCCcttataaatgtaatttgtgTCATATTACCTTCACCACCTTGGCGAATATGCACCGGCACATTAAAAGCCATCGACTCGATAATGACAAGAACAATAATAATGATGAGGATGATGAAGATTATCTTAGTAATGACAATGAAGAATATGAACGTGGTGTCTCATCGGATGCTTCGTCGGGTAACGAAAGCCGCGACAGTGTTAATGATAATATacgaaataataacaataataataataatagtaatagtaacaataataataattattcgatTGGTAAACGAAAAAATGCGAATGACGACCATGACGATTTAATAAGCCTGAAgcgtaaaaattacaataataataacctaattaataaaaattttataaatcaaacaaGTCAAATGCTGGTGGCGGctcaacaacagcaacaacaaaaattttgttgcccCGTTTGCGATCGTAACGATTTTATTAGTATGCTCACCTTAGAAAATCATATGGACAAGGAACATCCGAGTATACAAGCGCGATGTCGTCATTGCGACATTGTATTTAAAAGTCACAAAGCATTAAATGCCCACCGTTGCACAAAATCAACAAATCAAAGTATAACTCAGGGATTTAAAGATTTAACATTTATCGATTTTTCAAGTGAAAAATTTCCTATAATTGCGAAATCGATGTGCGAACAAACAATTCGCACACCAATAACATCGCAAAAATACGAATGTCCAAAATGTTATCGCGCTTTTCCATGTTCGACCGCGGTTGATATACATGTACGTGAATGCGGCGGTGGAAATGATTCAGCAATTGTTCAAGATTTTTCTATGCGTACTAATAAACGCGCCGACAGCAGTGACATCTCGGACGATGATGAATGCAAACGTGACGATTTCTTTGCTAACCTAGACTTACAAAATAAGACGTCGAATACATTTAATACATCGAACAATAGTTCACCCCGATCGACTGTTTCATCTGATATTATGAGAACACCATCTCTACATCACTCAATGGACTCGAAAGATTTGGCTGATATTCAATCGATAATTAATGTAACGTCATCGGGTGGATTATTGCGACATTTGGACAAACCGTTAAAAGATCACTTAGGCCAACCAAAAGAGATCGAGGAAGAGGCACAAGACGTATTCACCGCTGAATTCCGGAAAATGAAACTACGCGGTGAGTTTCCCTGTAAATTGTGTACTGCAATTTTTCCTAATTTGAGAGCACTCAAAGGCCACAATCGTGTACATTTATCGTCAGCTGGTGCCGGTCCATATCGGTGCAATATGTGTCCATATTCGATACATGATAAAGCGGCTTTAATTCGTCACATGCGAACACATAACGGTGATCGTCCTTATGAATGTGCAGTTTGTAATTATGCTTTTACGACCAAAGCCAATTGTGAACGCCATCTACGTAATCGGCATGCTAAAACTACAAGAGACGAAGTTAAACGCGCGATCATTTATCATCCATCAGAGGACTCATCAGCTGACGAACACCATCACAGTAAAAAGATGACAATGTTTAGTTCACCAGATTTTAATGAGGATGAAGATCGAATCCCAAAAGATCGAAGCACTCCAGTCTCATCAAGGCTTCAAGATTTATTATTACCTGATAATCATCATCAACGTTTAACTGCATCACTTTCGCCTTCACCATTGAAAATTCAAGTGAAAAGTTTAGAGAAATTGATTCACACAGAAACCATTAAAAGCGAGATAGAAGAAGAAGAAGTCGATGAAAAAAAAGTTGTTGTACCTAATAATGATGATACAAATCGATCTGAAGATGAAGACGATGAGGATGAAGAAGCGAATGATGAAACAAAACCGATCGATCTTTCAATGGATGCTCTAGATTTaagcaaaaaaactaaattcgatGAAAACAAAGCATTAAATCTGatcaacaataacaacaacgaTGATCTATCATTCTTCGAAAAGAATAAACAGCTGTTTATGgcacaacaacaatttttaaacgaaactCTTCCAAAAATCGATCCCTCACACTATTTGCAACTGTCCCATTTGTATCGAAATTTTATGTTTCCACCGCCTGGTTTCCCGCTTCCACCGTTTTTAATGCAAAATCCTTTATTGCAACCACCAAATATGGGTGAAATGCAGGACATGATGCGCGGTCAAATGTCTggaggaaatttaatatttaatcaacAATCATCTTCGTCGCCAACACCACCACTTTCAATCAAATCACAACCACTCGATGATTCTCCATCGAAAAGTGGTAGTGCGACTGAGTCACACAAGTACAGCCCAATAGCAACCCCAACAAATACTAACAATAATACACcacaacataataataataataataataataatcaggtacaaaataatcaaatgtcGAATGGGCCAGTTAAAATGGTTATTAAAAATGGTGTCTTGatgccaaaacaaaaacaacgaaGATATCGCACCGAACGTCCATTTGCTTGTGAACACTGTAGCGCAAGATTTACGTTACGTTCGAACATGGAACGACACATTAAACAGCAGCATCCACAGTTTTGGGCGCAGCGTCAACGAAGTGGACATAATCTATTGCGTCGTGGAAGCGGACCACCACCACCCGCTTCTCCACAACAACAGCCGCAACAACAATTGCAATCATCTCCACAGCAATCCATCAATCACTTGATCCCACAAGGTGGTGTATCGCAATTAACAAATCAATCGAATTTCACATCGATCtctgatcaagtaaaatatgcCATTCTCGCTCAACAACTCAAATACAATAAggatagtaataataaaatggGAATGCCATCGTCACTAGTACAATCCCTAAATAATCAAAGTCACATGCCCCCGAACAATAATAACAACTCGATATatgcaaatcaaaataatcaatCTACTAACAACGATGAGGAAGATGAACCTCAATTAGTCATTGACGAAGACTCACAACCGGAAGACTTATCCAAATTGGAATCACCAAAGAATAATGCTGTCACACCAAATAATGAACTACACCATAATAATGTAATTGAGGCGAAAAAAATTGCCGAAACTATATTGGAACAAGCCAAAAAAGCGTCATCTGGTATGAACCCTACTGCTACAGTTCCACCAACAACTATAAATCCAGAAACTACTaaagattttgatttaaaaatttcaccaaatttaattgccaaatcagaaaatttatcaaactaTAATCTATACCAAACGAAAGATAATCACCGAGAAGAAGGTGATTTGGCATCGGTATCACGGTTGGTGGATAATGcgtttgggaatttttttggcAATAATGAAATTAGCGCACCAATGGAACACAGTGATGAAGATGGTTTAGTGGCATCGGGCAGTGCGTCCGAAAGTAATACTTCAGGGCCTGAAGATCATGTGTCTGCCATACCAATTGAAccacaaaagaaaaaatcagcaTACAGTTTAGCACCAAATCGTGTCAAGTGTCCATATTGCCAACGTTCATTTCCATGGTCCAGCTCTTTGCGGAGACATATTTTAACACATACTGGGCAAAAACCATTCAAATGTTCGCACTGTCCATTACTGTtcacaacaaaatcaaattgtgATCGCCATTTACTGCGCAAACACGGAAATGTTGAATCAGCCATGTCAGTCGCTGTGCCAATCGATGAAAATATTCCCGAACCGATAATAAAGAAAGAACCAAAGgaatatattgaaaatgaacCGAATAAATCACCCAAAATGACAACCAACATAAATCAAGCTGCTGCAtccattccaaatttaaatttagcattGAATTTAAAAGCTGAGCTCAtgaatagtaataataatgcATCAAATATACCTGTTAGTACCGAACTTCCATACAAGTGTCATTTATGCGATGGTTCGTTTTCGGAACGAATGCAATGTTTAGAACATATTCGCAATTCACATGCACAAGAATTTGCATTACTATTGGCCAAAGGTGCTATTGATGCAGATTcagaaaataattcaaatgtaCAACAAGCCCAACATAATAACGAACATAATATGGACGATGATAATAAAGAGGGAAAAGGGAAATATCCAGACTATGCTAATCGAAAGGTCATTTGTGCTTTCTGTGTCCGAAGATTTTGGTCGACAGAAGATTTACGGCGACATATGCGAACTCATTCCGGGGAGCGGCCATTCCAGTGTGACATTTGTTTACGTAAATTTACGTTAAAACACAGTATGTTGCGACACCAGAAAAAGCATAGTGCACATAATAataaccaacaacaaaataatagtgCATCGGATATGTCGGATGAAGAACCGCCAACCACAATGATTCCAAATAAATTACTCAACATTCCTGATTTAATACCAAAAGACGTAGCACACAGTACACAATGGAAATTAAGTCATTTACAAGCAAAACTATTTGCTCAACAACACCACAACGAAAGTGCAggcacaaataataataatagtaataaccatcatcatcaacatcatcatcatcatcatcaagcTCCATCCCCACCTTCATTTCTTATTTCACCATTTCTACAGTTACAACAGCGTTTTGCTAGTTTAGCGCACGCCGGACTTGATGGACACGCGAAAGATCATCATGATCAAGATGAATCGGATTTAATTGGTAATCTACTCGGTATAAGTGACCAAGGTATTTTAAATAGAGTTTTGGTATCGTCAGCTGATGAAGCTGCTAAATTGTTAggagttgaaaaataa
Protein Sequence: MDRRISTNSESSIEPMDVSVSNKTTSSDGTNNTSSAMAISKISEPNHSESDNGGIESEENDENIVRRENLRLHNSSSHIDTKMLRKKFRLMNNNNNTNNNNNNNNNNNSSNNTAATDKNLSIESHGNLENFQCHICSKHLTTSIALVRHLQAHSLESESPYKCNLCHITFTTLANMHRHIKSHRLDNDKNNNNDEDDEDYLSNDNEEYERGVSSDASSGNESRDSVNDNIRNNNNNNNNSNSNNNNNYSIGKRKNANDDHDDLISLKRKNYNNNNLINKNFINQTSQMLVAAQQQQQQKFCCPVCDRNDFISMLTLENHMDKEHPSIQARCRHCDIVFKSHKALNAHRCTKSTNQSITQGFKDLTFIDFSSEKFPIIAKSMCEQTIRTPITSQKYECPKCYRAFPCSTAVDIHVRECGGGNDSAIVQDFSMRTNKRADSSDISDDDECKRDDFFANLDLQNKTSNTFNTSNNSSPRSTVSSDIMRTPSLHHSMDSKDLADIQSIINVTSSGGLLRHLDKPLKDHLGQPKEIEEEAQDVFTAEFRKMKLRGEFPCKLCTAIFPNLRALKGHNRVHLSSAGAGPYRCNMCPYSIHDKAALIRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHAKTTRDEVKRAIIYHPSEDSSADEHHHSKKMTMFSSPDFNEDEDRIPKDRSTPVSSRLQDLLLPDNHHQRLTASLSPSPLKIQVKSLEKLIHTETIKSEIEEEEVDEKKVVVPNNDDTNRSEDEDDEDEEANDETKPIDLSMDALDLSKKTKFDENKALNLINNNNNDDLSFFEKNKQLFMAQQQFLNETLPKIDPSHYLQLSHLYRNFMFPPPGFPLPPFLMQNPLLQPPNMGEMQDMMRGQMSGGNLIFNQQSSSSPTPPLSIKSQPLDDSPSKSGSATESHKYSPIATPTNTNNNTPQHNNNNNNNNQVQNNQMSNGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQFWAQRQRSGHNLLRRGSGPPPPASPQQQPQQQLQSSPQQSINHLIPQGGVSQLTNQSNFTSISDQVKYAILAQQLKYNKDSNNKMGMPSSLVQSLNNQSHMPPNNNNNSIYANQNNQSTNNDEEDEPQLVIDEDSQPEDLSKLESPKNNAVTPNNELHHNNVIEAKKIAETILEQAKKASSGMNPTATVPPTTINPETTKDFDLKISPNLIAKSENLSNYNLYQTKDNHREEGDLASVSRLVDNAFGNFFGNNEISAPMEHSDEDGLVASGSASESNTSGPEDHVSAIPIEPQKKKSAYSLAPNRVKCPYCQRSFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVAVPIDENIPEPIIKKEPKEYIENEPNKSPKMTTNINQAAASIPNLNLALNLKAELMNSNNNASNIPVSTELPYKCHLCDGSFSERMQCLEHIRNSHAQEFALLLAKGAIDADSENNSNVQQAQHNNEHNMDDDNKEGKGKYPDYANRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHQKKHSAHNNNQQQNNSASDMSDEEPPTTMIPNKLLNIPDLIPKDVAHSTQWKLSHLQAKLFAQQHHNESAGTNNNNSNNHHHQHHHHHHQAPSPPSFLISPFLQLQQRFASLAHAGLDGHAKDHHDQDESDLIGNLLGISDQGILNRVLVSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01455207;
90% Identity: iTF_01458989;
80% Identity: -