Thel045862.1
Basic Information
- Insect
- Tipula helvola
- Gene Symbol
- -
- Assembly
- GCA_963556165.1
- Location
- OY744481.1:392161087-392163311[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.081 30 8.1 0.2 2 23 248 269 247 269 0.96 2 9 0.095 36 7.9 0.1 1 21 342 362 342 363 0.90 3 9 2.9 1.1e+03 3.3 0.5 1 23 477 502 477 502 0.94 4 9 0.00019 0.072 16.4 1.2 3 22 510 529 509 529 0.94 5 9 2.2e-05 0.0084 19.3 0.6 1 23 536 558 536 558 0.98 6 9 1.7e-06 0.00064 22.8 0.8 1 23 564 586 564 586 0.98 7 9 4.7e-06 0.0017 21.5 0.5 1 23 592 614 592 614 0.98 8 9 0.0017 0.63 13.4 0.2 1 23 620 642 620 642 0.96 9 9 2.3e-06 0.00086 22.4 2.1 1 23 648 670 648 670 0.98
Sequence Information
- Coding Sequence
- ATGTTAGAAGAAAATGAATATGAATTAGAAATAAGCTCCGACGAAATATGTCGATCGTGTCTtaatcaagaaaaaaatttaaaaagtctcTTCTGCAGTGAAATTTTGGATGGACAAATTGTgtcatttccaaaaatttttcaagATGTTACCGATCTgaagatagcAAAGAATGATAACCTTCCGTCACGAATTTGcctaaattgcaaattaaaaataaatgagtttTACATATTCAAAGAGAAATGTCGGCGATCACATGAACTGGCACTATCCATATTTTCTAAAGTTGAACCCACTGAAGTATGGTCGCTCGAATCTGAAAATCCTACAAAAAATCATGATGAGGAGACTAGCAGCAGCGACACGGCTACAGAAACGAACATTATTGATTCTAATGTAACAGTTAGTACAGAAATACCGTCACAATTGCTAGACGAAAATtcatctgtaaatattataaaaaatgaagtccTAGCATCGTTGAATGATGAAGATTGTGATAAATCTGTCATTGATGTTGCCAATATTAAATCAGAACCAAACATAGTCGATGTTACCAATGTAGATTACATCGAGGATGAGCAAGCGGAAGAGGAGGCAACTGAAAGTGGTGATACCGAGGGTGATTTCGacgaattaaaaaacacaaccgAATATTTAGAGGAACAGGAGTTTGGGGTGGTCGAATTgatcgatgatgatgatgtttcCTTTACACCTCCTGAATTGCGTGAAATATCTTGCGAAATATGTAAAATcgaattcttaaataaaatggaattcgtTGATCATATAAAAAGTCACGATTTAACCGATGGCATCATCCATATCGAATCTAATACATCTCATGAGCTTGATAAAAAGGAGCCGAGACAACGTAAAAGTGGAAAATACGGTGACTATTGTAAATTTTGCAAAAGTTTCGTAAAACCCAACAAATCAAAAGATaacgatttatataaaaaacatatCGATTTGCATCgacaaacttttaaaattattttagagacGATAGATTTGTACAAATGTGGCACTTGTAATTTGGTTTTCATCgataaaattatctttaaagAGCATATTAATTCACCCGAATATTACTGTAAGGAAACTATTACTGCGGATGTAGATGTGTCTGACTCTGAATCTAGATGtattgaaatggatttttttgaaaacgatTTCGAACCCCAAAAtcctattaaaataattaattgtaccAAAATTAACGATAATGGTTTGTTAGAATGTAAATCGTGTACTGAGTTTCAAACATCAGAGATTGATATGCTGGTAGAACACACTGAAAAGGAGCACAATGATAATTTAGATTTCTACAATAatggtttaaatatttgtaatatttgtaaCAAATGGTCAGCCTCATTGGTAGAAATACTAATGCATATCTATTTCCATGCCAGTACATATAATTGcccatttttaaattgtgctatGCTTTATAattcgtttggaaaattaaatacacaTTTGGAGCGAACACATTTATTCCTGAATACGCCAAATTGCAGTCACtgtgatgaaaaatttaaaacgtacGATGATTTAACGATTCATTTGAAGCGCTTTTGTGAAAAGCGAATTTTCAAATGTGACGACTgtggtaaaacatttttatcgaattCAAGTCTGGGAGTTCATAAACGTATacataatcaaaatataatgtATGTGTGCCAATTTTGCGGGAAAAAATTCACACAAAGTGGTGATATGAAAATACATGTACGAATGCATACGGGCGAGAAACCTTATCAGTGCCCGTTGTGTCCAAAACAATTCCGAACTTCTGGCAATCGACAGGATCACATGGAATCGCACAatgattccaaaaattttttttgtGAAATATGCCTAAAATCTTTTAAAGGCGAACGAGTATTGAAGGCCCATATGGTTATTCATTCGGGTGAAAAGAAGTTTATTTGCCCGATCTGTGGCAAGCAATTTTATAGAAAACAGCACGTAAAAAGTCATTTGCGGGTGCATGACAGGCGACCAAATAAACACAAGGTCATGGATTGGCTAGAAGACGATGGTGGATCAGAATCGAATGCTGATACTAAGCTTGAAAAATAA
- Protein Sequence
- MLEENEYELEISSDEICRSCLNQEKNLKSLFCSEILDGQIVSFPKIFQDVTDLKIAKNDNLPSRICLNCKLKINEFYIFKEKCRRSHELALSIFSKVEPTEVWSLESENPTKNHDEETSSSDTATETNIIDSNVTVSTEIPSQLLDENSSVNIIKNEVLASLNDEDCDKSVIDVANIKSEPNIVDVTNVDYIEDEQAEEEATESGDTEGDFDELKNTTEYLEEQEFGVVELIDDDDVSFTPPELREISCEICKIEFLNKMEFVDHIKSHDLTDGIIHIESNTSHELDKKEPRQRKSGKYGDYCKFCKSFVKPNKSKDNDLYKKHIDLHRQTFKIILETIDLYKCGTCNLVFIDKIIFKEHINSPEYYCKETITADVDVSDSESRCIEMDFFENDFEPQNPIKIINCTKINDNGLLECKSCTEFQTSEIDMLVEHTEKEHNDNLDFYNNGLNICNICNKWSASLVEILMHIYFHASTYNCPFLNCAMLYNSFGKLNTHLERTHLFLNTPNCSHCDEKFKTYDDLTIHLKRFCEKRIFKCDDCGKTFLSNSSLGVHKRIHNQNIMYVCQFCGKKFTQSGDMKIHVRMHTGEKPYQCPLCPKQFRTSGNRQDHMESHNDSKNFFCEICLKSFKGERVLKAHMVIHSGEKKFICPICGKQFYRKQHVKSHLRVHDRRPNKHKVMDWLEDDGGSESNADTKLEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01458929;
- 90% Identity
- iTF_01460601;
- 80% Identity
- -