Basic Information

Insect: Tipula helvola
Gene Symbol: -
Assembly: GCA_963556165.1
Location: OY744481.1:255691407-255693345[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0045 1.7 12.1 0.7 2 23 210 231 209 231 0.95

2 12 3.4e-05 0.013 18.7 6.2 2 23 270 291 269 291 0.98

3 12 0.0017 0.63 13.4 7.8 1 23 297 319 297 319 0.98

4 12 1.5e-06 0.00057 23.0 0.8 1 23 325 347 325 347 0.99

5 12 1e-05 0.0039 20.4 1.7 1 23 353 375 353 375 0.98

6 12 0.01 3.9 10.9 2.5 1 23 381 404 381 404 0.95

7 12 0.069 26 8.3 4.1 3 23 429 449 428 449 0.98

8 12 0.00017 0.065 16.5 0.4 1 23 453 476 453 476 0.97

9 12 0.01 3.8 10.9 2.0 1 23 482 505 482 505 0.96

10 12 2.8e-06 0.001 22.2 1.1 1 23 512 534 512 534 0.98

11 12 0.00013 0.05 16.9 3.3 1 21 540 560 540 562 0.95

12 12 0.0032 1.2 12.5 0.2 1 23 568 590 568 590 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0045	1.7	12.1	0.7	2	23	210	231	209	231	0.95
2	12	3.4e-05	0.013	18.7	6.2	2	23	270	291	269	291	0.98
3	12	0.0017	0.63	13.4	7.8	1	23	297	319	297	319	0.98
4	12	1.5e-06	0.00057	23.0	0.8	1	23	325	347	325	347	0.99
5	12	1e-05	0.0039	20.4	1.7	1	23	353	375	353	375	0.98
6	12	0.01	3.9	10.9	2.5	1	23	381	404	381	404	0.95
7	12	0.069	26	8.3	4.1	3	23	429	449	428	449	0.98
8	12	0.00017	0.065	16.5	0.4	1	23	453	476	453	476	0.97
9	12	0.01	3.8	10.9	2.0	1	23	482	505	482	505	0.96
10	12	2.8e-06	0.001	22.2	1.1	1	23	512	534	512	534	0.98
11	12	0.00013	0.05	16.9	3.3	1	21	540	560	540	562	0.95
12	12	0.0032	1.2	12.5	0.2	1	23	568	590	568	590	0.98

Sequence Information

Coding Sequence: ATGCTAGGAACAGAAGAATCTTTCGACTCTGATAAAACTACTAAATCGGATGAAATATGTCGTGCATGTTTATGCAAATCGGATAATCTAAATTCATTGTTCAGCGAAGCGGTTTTGGATCAAGATGAATCAGAAAGTGATGAGGAATCAGCCCAGAGTAGTCGTGAAATCGAACTCACttatcttaaattatttgaagattGTACATCAATAAAGTTGGACAAGTTTGATGAAAAACCAACAAGTTTGTGCCCCGATTGTATTGAGGAATTGGTCGCATCCTACAGCTTTCGCAATAAATGTATCAATTCGGATAATGAACTGGGTACTCTGGTTGTCGAAGAGGAACATAATGATGATGAAAGAGGGGTTTCCGAAGAGGTAGACATTAAAACAGAgacaactaatttaaaaatcgttGCCATTGAAAATCTCGTCAAAGCAAGTGAAACTCCGGTTGATGACGAGGAAAGTTTTATGTATGAGGATCATTTAATTGAGATGGCAGATGACGAGGATGACCATCAAGatcattttgaattatgtaCGGAAGACAAAGTGAAACTTGACGACGAAGAAGATGAGGAGCATTCGATTGAGGACGAAAATTCAGGTGATGACATATTGGAGTGCCGCATctgtaaattaagttttgtgaGTTTAAGCGAATTTCATTTGCACTATGCCGTTCATAATCCAGAACGACCATTTAAATGTTTCGAAAAAAAGTGTAAACAATGCTCGTTTAAAACCCAAGAAGAACTTGAAATGCACAATTTCGTATATCACTCCCCCGAAAATGAGTCCAAGTGTTCGTACTGTAAAAAGGAATGTAAAAACAAACGGTCGCTTAAAGCCCATATGAAGACGCATTCAACGGATCGACCgcacaaatgcaaaaactgcgaTAAGGCGTTTATATTTACGCACCATCTAAAAAATCACGAGAAAATACACGAAAATGTCAAGAAATATACTTGCTCTGATTGTCAGAAGTCGTTTATCAACAAAGATCGGCTAGCACTGCACCAACGTATACATACTGGGAAACGGCCGCATAAATGTTCTACCTGTCAGAAAGCGTTTATAAGTGCGtcatcattaaaaattcattatgcGACGCATACGGCcgaaaaaccatttttgtgtacTCAGTGCGGAGCGTGCTTTAAACTAGAAGTATTCCTAAACACGCATCTTAAGAGATCACATTCAGTTAACAGTAATACGGTTGCGTCAGTGACGAAACCGAAATCAATCAAACCGAAGGAGGAACAAAAATTCTGTAATCTGTGTAATACTAAATTTGAAACTTCGATTGAATGTAATCAACACATGAAAACCCATAGCTACAAATACTCATGCCAAATTTGCACTAAGCCATTTGCACTCAAATCAAAGCTAGATTCGCATATTAAAAATGCTCACGCGACAAATTTAAGATACATCTGCGGGCAATGTTCAGCAAAATTTCATCGGCCTGATTTGCTGCGTTATCATTATTTGCGTAAACATGCTGATGGGAAATTACCATTCACTTGCGAAATTTGTGATCGCGGATTTATTACGAACAGTGACTATAAGGTACATAAACGAAGGCATTATGGCGAAAAACCATATGAGTGTAACATATGTGATAAACGGTATGTAACAACTTCCGAATTGCGTCAGCACAAACGATGTCATACGGGTGAGAAACCATATGTTTGCAATTTATGTGATAAATCTATTGCAACAATTAATTTGCTCCTGTATCACATCAAGCAGCATAATAAAGATGGCAGTATCGATACTGAGCGTTACAATCAAGAGGTGAAGGCGATTGAAAGTATTGCGGAAGAGCAGATAGATGAAGTGCAGCCGGAGGAgatagaaaatgattaa
Protein Sequence: MLGTEESFDSDKTTKSDEICRACLCKSDNLNSLFSEAVLDQDESESDEESAQSSREIELTYLKLFEDCTSIKLDKFDEKPTSLCPDCIEELVASYSFRNKCINSDNELGTLVVEEEHNDDERGVSEEVDIKTETTNLKIVAIENLVKASETPVDDEESFMYEDHLIEMADDEDDHQDHFELCTEDKVKLDDEEDEEHSIEDENSGDDILECRICKLSFVSLSEFHLHYAVHNPERPFKCFEKKCKQCSFKTQEELEMHNFVYHSPENESKCSYCKKECKNKRSLKAHMKTHSTDRPHKCKNCDKAFIFTHHLKNHEKIHENVKKYTCSDCQKSFINKDRLALHQRIHTGKRPHKCSTCQKAFISASSLKIHYATHTAEKPFLCTQCGACFKLEVFLNTHLKRSHSVNSNTVASVTKPKSIKPKEEQKFCNLCNTKFETSIECNQHMKTHSYKYSCQICTKPFALKSKLDSHIKNAHATNLRYICGQCSAKFHRPDLLRYHYLRKHADGKLPFTCEICDRGFITNSDYKVHKRRHYGEKPYECNICDKRYVTTSELRQHKRCHTGEKPYVCNLCDKSIATINLLLYHIKQHNKDGSIDTERYNQEVKAIESIAEEQIDEVQPEEIEND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460535;
90% Identity: iTF_01460535;
80% Identity: -