Basic Information

Insect: Tipula helvola
Gene Symbol: -
Assembly: GCA_963556165.1
Location: OY744481.1:6416193-6423126[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 3.8e-06 0.0014 21.7 1.7 1 23 304 326 304 326 0.98

2 9 7.6e-08 2.8e-05 27.1 1.6 3 23 334 354 332 354 0.98

3 9 0.00033 0.12 15.6 0.3 1 23 360 382 360 382 0.98

4 9 6.4e-06 0.0024 21.0 0.2 1 23 388 410 388 410 0.98

5 9 2.8e-05 0.01 19.0 1.7 2 23 499 520 498 520 0.96

6 9 3.6e-09 1.3e-06 31.3 1.6 1 23 526 548 526 548 0.98

7 9 0.012 4.6 10.7 1.0 3 23 556 576 554 576 0.97

8 9 0.00024 0.088 16.1 0.9 1 23 582 604 582 604 0.99

9 9 0.02 7.4 10.0 1.3 1 23 610 634 610 634 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	3.8e-06	0.0014	21.7	1.7	1	23	304	326	304	326	0.98
2	9	7.6e-08	2.8e-05	27.1	1.6	3	23	334	354	332	354	0.98
3	9	0.00033	0.12	15.6	0.3	1	23	360	382	360	382	0.98
4	9	6.4e-06	0.0024	21.0	0.2	1	23	388	410	388	410	0.98
5	9	2.8e-05	0.01	19.0	1.7	2	23	499	520	498	520	0.96
6	9	3.6e-09	1.3e-06	31.3	1.6	1	23	526	548	526	548	0.98
7	9	0.012	4.6	10.7	1.0	3	23	556	576	554	576	0.97
8	9	0.00024	0.088	16.1	0.9	1	23	582	604	582	604	0.99
9	9	0.02	7.4	10.0	1.3	1	23	610	634	610	634	0.95

Sequence Information

Coding Sequence: atggcaatAAATTTTTCGGCCTCATTTGCTGCTTGTCTGGCGGCAGGATTAAAAGTACCAAGACAAATAATGTACTGTATCTCACAGGATACAGGTGCAccatatgtattatataaagaTTCACAAGAGGCTGCTGAACGGGGTGCGCTAACCGGGCAATGGGGAACAGATGTATATCAATCGGCGATACAACAAAGTCCTCAGCAAGCACATGTCACAACGCACAATGCGGTACAAATAACGGCAGTGcaacaaaatcaacaacaacaacaaacggCACCGCAAAGTCCGCAGGGCGATGAAAATACAACCGGAAATAATAGTGGTAGCATAAATAGTCCGGCCCATAGTCCTGCATATCAAAGCAATAATAATCAGGAAATGGATGATGATGCCTCAGCAGCTCAaGTAACGTCTATGCACAATCAGCAGCAAGCCCAATCTAATCAACCAGCTGTGCCCGTAAcgcaaaataatcaaaatcaacAGACTTCCGAGCAGCAAACAATTGACCTGCAGCAAAATGAGCAGAATCAAAATGGACAAGCTCAACAAATAcagcaacagcaacaacaacaacagcagcaacAAACTacacaacagcaacaacaacaagctCAAAATACCAATACCCAACCGAATGGACCACCATGTTTTGCTGAACCCGCGCAACAATCAGAATTAGCTCAGTATTATGCACAGCGGCATCCTGCGGCACAAGGCGCAATGCTGGCACCAGCCGGATTTCCACCCCTCCACTATCTAAACAAAACTATTCCAATAAGTGGTGGAATGGATCAAAGTGCAATTGAAACATATACAATGCCGGATCTACTGCCCGGCGGCCATCAAATGGGACATCACAATCAATCGCCGagtaataaatcgaaaaattcagATTTGCGATTATTCAAATGCCTGACATGTGGGaaagattttaaacaaaaaagtacATTACTGCAACACGAGCGAATCCATACAGATGCCCGTCCATTTGGTTGTCCTGAGTGTGGGAAACGTTTTCGACAGCAATCCCATCTGACCCAGCACGTTCGGATACATGCAAACGAAAAACCATTTTCATGTGGGTTATGTCCCAGAAGTTTCAGACAACGGGCTATTCTCAACCAGCACGTTCGCATCCATTCGGGTGAGAAGCCCTACGCGTGCCCAGAGTGCGGCAAATCATTTCGCCAGAGGGCCATCCTATATCAACATGTGCGCACCCATCAAGatgtGTCACctcatttaatatttaaaaatggccCACATCCGACACTATGGCCTAGTGATGTACCATATCCGGGCGATGAGACAAAAGATGAAAATGGTTCGGGTTTCAATGAGGATGGTTCGCCGAGTGAAGGTCGTACATTATTCTCGCAAAAAGGTGGCATACATTATCCTGTTTACTTTAAAGATGCGAAAGGACAAAAAGGTTTATTACCCGATGTTATACAACATGGACGATCGTCTGGTATGCCCTTGTATGTACGTTGTCCGATATGTcaaaaagaatttaaacaaaagaGTACACTGTTACAACACGGTTGTATCCATATAGAATCTAGACCATATCCATGTCCAGAATGTGGTAAACGTTTTCGACAACAATCACATTTAACGCAACACTTACGGATACATACAAATGAGAAACCATTTGGATGTTTATATTGTTCGAGGTATTTCAGGCagagaacaattttaaatcaaCACATAAGAATACATACGGGTGAAAAACCATACAAATGTGTACAGTGCGGAAAAGATTTTAGACAAAAGGCCATATTGGATCAACATACCAGAACGCATCAGggCGATCGTCCATTCTGTTGTCCGATGCCAAATTGCCGAAGGCGATTCGCAACCGAACAAGAAGTGAAGAAACATATTGACAATCATATGAATCCGCATGCATCAAAATCACGTCGCGGCGGTGGCATAAATGCTGCATCAATGCTGGGAGCTGTAACGCAAGCGGTTAGTGGTGTGACAGGTAATGGTGATGGTCCAAAACCATCAACTTTTTTAACTATggataaacaaacaaatttaataccaCGTATGGGACCTGTTGTTAAACATGAATTATATTTTCCGCAATGTTATGCACCACCATTTAATCAGGCATTTGGTGGGCAACAACAAGCTCATAGTGGTAGTACTGCAGCAACAACTGTTACACCAACAGTACAAACAGTGGCTCAGTGA
Protein Sequence: MAINFSASFAACLAAGLKVPRQIMYCISQDTGAPYVLYKDSQEAAERGALTGQWGTDVYQSAIQQSPQQAHVTTHNAVQITAVQQNQQQQQTAPQSPQGDENTTGNNSGSINSPAHSPAYQSNNNQEMDDDASAAQVTSMHNQQQAQSNQPAVPVTQNNQNQQTSEQQTIDLQQNEQNQNGQAQQIQQQQQQQQQQQTTQQQQQQAQNTNTQPNGPPCFAEPAQQSELAQYYAQRHPAAQGAMLAPAGFPPLHYLNKTIPISGGMDQSAIETYTMPDLLPGGHQMGHHNQSPSNKSKNSDLRLFKCLTCGKDFKQKSTLLQHERIHTDARPFGCPECGKRFRQQSHLTQHVRIHANEKPFSCGLCPRSFRQRAILNQHVRIHSGEKPYACPECGKSFRQRAILYQHVRTHQDVSPHLIFKNGPHPTLWPSDVPYPGDETKDENGSGFNEDGSPSEGRTLFSQKGGIHYPVYFKDAKGQKGLLPDVIQHGRSSGMPLYVRCPICQKEFKQKSTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCLYCSRYFRQRTILNQHIRIHTGEKPYKCVQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATEQEVKKHIDNHMNPHASKSRRGGGINAASMLGAVTQAVSGVTGNGDGPKPSTFLTMDKQTNLIPRMGPVVKHELYFPQCYAPPFNQAFGGQQQAHSGSTAATTVTPTVQTVAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460514; iTF_01458880; iTF_01054625; iTF_01052549; iTF_01457780; iTF_01053720;
90% Identity: iTF_01054625;
80% Identity: -