Basic Information

Insect: Tipula helvola
Gene Symbol: hang
Assembly: GCA_963556165.1
Location: OY744483.1:342692650-342698725[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.00063 0.23 14.8 0.4 3 23 272 293 271 293 0.96

2 24 6.2 2.3e+03 2.2 1.3 6 22 370 386 366 386 0.90

3 24 0.076 28 8.2 0.7 3 21 396 414 395 415 0.95

4 24 0.032 12 9.4 0.5 3 23 457 478 455 478 0.90

5 24 5.8 2.2e+03 2.3 0.2 3 20 492 509 490 511 0.91

6 24 0.035 13 9.3 1.1 3 23 520 541 518 541 0.94

7 24 0.0014 0.51 13.7 0.4 3 23 576 597 574 597 0.95

8 24 2e-05 0.0073 19.5 1.2 1 23 605 628 605 628 0.96

9 24 0.099 37 7.8 0.2 2 23 654 675 653 675 0.96

10 24 0.0022 0.81 13.1 0.6 1 23 678 700 678 700 0.98

11 24 0.00078 0.29 14.5 1.3 1 23 706 729 706 729 0.98

12 24 0.051 19 8.7 0.2 2 23 815 836 815 836 0.97

13 24 0.028 10 9.6 0.9 2 23 863 885 862 885 0.94

14 24 0.028 11 9.6 2.5 2 23 894 916 891 916 0.96

15 24 0.01 3.7 11.0 6.8 1 19 943 961 943 966 0.91

16 24 0.0032 1.2 12.5 1.1 1 23 1001 1023 1001 1023 0.99

17 24 0.0011 0.4 14.0 1.2 1 23 1031 1054 1031 1054 0.93

18 24 6e-05 0.022 18.0 1.1 2 23 1062 1083 1061 1083 0.97

19 24 0.001 0.38 14.1 2.3 1 23 1111 1133 1111 1133 0.98

20 24 0.045 17 8.9 0.1 1 23 1185 1207 1185 1207 0.92

21 24 0.001 0.39 14.1 0.3 2 23 1245 1267 1245 1267 0.91

22 24 0.37 1.4e+02 6.0 0.5 2 23 1292 1313 1291 1313 0.95

23 24 7.2e-06 0.0027 20.9 0.7 3 23 1327 1347 1327 1347 0.99

24 24 0.00048 0.18 15.1 0.8 2 23 1432 1453 1431 1453 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.00063	0.23	14.8	0.4	3	23	272	293	271	293	0.96
2	24	6.2	2.3e+03	2.2	1.3	6	22	370	386	366	386	0.90
3	24	0.076	28	8.2	0.7	3	21	396	414	395	415	0.95
4	24	0.032	12	9.4	0.5	3	23	457	478	455	478	0.90
5	24	5.8	2.2e+03	2.3	0.2	3	20	492	509	490	511	0.91
6	24	0.035	13	9.3	1.1	3	23	520	541	518	541	0.94
7	24	0.0014	0.51	13.7	0.4	3	23	576	597	574	597	0.95
8	24	2e-05	0.0073	19.5	1.2	1	23	605	628	605	628	0.96
9	24	0.099	37	7.8	0.2	2	23	654	675	653	675	0.96
10	24	0.0022	0.81	13.1	0.6	1	23	678	700	678	700	0.98
11	24	0.00078	0.29	14.5	1.3	1	23	706	729	706	729	0.98
12	24	0.051	19	8.7	0.2	2	23	815	836	815	836	0.97
13	24	0.028	10	9.6	0.9	2	23	863	885	862	885	0.94
14	24	0.028	11	9.6	2.5	2	23	894	916	891	916	0.96
15	24	0.01	3.7	11.0	6.8	1	19	943	961	943	966	0.91
16	24	0.0032	1.2	12.5	1.1	1	23	1001	1023	1001	1023	0.99
17	24	0.0011	0.4	14.0	1.2	1	23	1031	1054	1031	1054	0.93
18	24	6e-05	0.022	18.0	1.1	2	23	1062	1083	1061	1083	0.97
19	24	0.001	0.38	14.1	2.3	1	23	1111	1133	1111	1133	0.98
20	24	0.045	17	8.9	0.1	1	23	1185	1207	1185	1207	0.92
21	24	0.001	0.39	14.1	0.3	2	23	1245	1267	1245	1267	0.91
22	24	0.37	1.4e+02	6.0	0.5	2	23	1292	1313	1291	1313	0.95
23	24	7.2e-06	0.0027	20.9	0.7	3	23	1327	1347	1327	1347	0.99
24	24	0.00048	0.18	15.1	0.8	2	23	1432	1453	1431	1453	0.96

Sequence Information

Coding Sequence: ATGGATAATAGTGAAATTACAATATCAAATAGACAAATTTGTTGTCGTCTATGTTTGGCACCAGATAATGAATGTGTTCCCATTTTTACAAATTCGGCAGCTGATAAAGAACCATTATCATCAAAAATTCAAGCTTGTGTTAATATTaaggttcATGAAACCGATAGACTATCATCACGAATCTGTCATTATTGTATAAGTTATTTGAATTCCTGGcaaagcttcaaaaatcgatGTTTGGCTGCACAGAAAAAGCAAAGaacattgttatttttattatcggagaaacaaaaatttcaaagacaGCATGCAGCGACACAGGCAGCCACCATAGCAAGGCGACAACTGCAGCATCAATTAcagagaaatttattaaattttgttgccaACAAAGATGGTGGTAGTGGTATCCAAAACGAGGTTCAAGACGAGGATAGAAATAATGCAACGAATCAGATAAAGAATAATGACGTTGACTTAACCTGTGTTAAAGAGGAACCACAAGAAATGATATCAGACGATGAAgatcAAAATAATATGAATGTGGAACTAGATCCGTCACAATTTTTAGCAAATAACGAGGATGATGATGATTATCAAGCGTATGATGAACGTGAGCCAGTTCCCGCACCTATAATATCAATGGAAGAAGGCCCACCTATATTAACTTCTCTCGGACTTACTCACGTAAATCATGTAAATTCTTGCAATTTTGTGaaaactGAAGCTGATTACGGTGACGATCTAACAAATTCTGGCGAGCTGTACAACTCATTCAACGATCAAAAATTAGGGGGACCAATACCCGGTGCTTGTTCAATTTGTgacatgaaattttcaaatcgcGCAAACGCCCGGCGACATGAGCGTAACATACATGGTATATTGCCGAACCCGCTAACATTTACGCCACAAATTTCCAATCCTACCACAATAAATCCAGCTGCCGTTAAACCAGTAATTAGCCGCAAAGTTATTCATGTTCCTGAAGTTTATAATTATGAAACTCCTGAAAAATATCGACCGTATTTAACAGAAAATAAGATCAAATTtattcgtaataatttaacatttcttGAACAATATCAAGATATGATATGCGCGTGTTGCGACCGACAATACCAAACCTATAAAGCATTTATGTCTCACAtgagaaaaaaatatcaatttttaccacgaaatttatgttttaaatgtttaaaacaatttgaaaccAAAGGACAATTTAttgcacatttaaaaaaaagaaattgtattaatttatataaattgtatatgaTTGATGAATCAATAACGAAACCGGAATTAACCGAAGAAGAAAAGGCTCGTAACAAAACCAAAGATATTCTTGCAAATAAAGACTATGGATGCAAATTGTGTGGATTaacttttaagttaaaaatggattttcgTGCACATGTATTTGAACAGCATGCCGATAATCAAAAAGGCAATGACGTAGCATTAACTATTTGTGGATTTTGCAATGTAAAATTCGAGGATGCCCCTACCAAAAAAAGACATTATACCAATTTAGAATGTATAATTTCGATTATATGTGGCTCATGTGGTGAGAAATTTACTCAGCATCCACATTACATTGATCATGTATATACGAATCATTTATCGAATGCAAAtgcaaatgattttaatgaagcTGATTCTTATGACGGTGAATTTGAAACATCATATCAATCAACATCACGTTTACGAACTCCACAAAATTGTGCTGTTTGTGggaaacaatacaataattattataatgtgTTGCGGCACATGGAAAGTAAACATCCAGATCAATTACCACAAACGTATTCATGTGAACATTGTCAAACTGGATTCCCGCGGCAGTCTGAACTACGGgagcatataaaattaaatcatcgcGACAGTTTATTTCGGACACCAACATCATCGGCAAATGTATCTGTAAGCGGTGGTATAAAACAATCAATAATTTCATGTAACGATTGTGGTTTAGTATGTGAGACGAGAGATATCTGGATTGAACACATGACAACTCATTCAAAATTCGTATGTCCACAATGTGAATATAAAACGGAATCGAAAGAAGAATACAACAATCATTTGAgtacacatttaaaatttaagttatacTCTTGCGTAATTTGTAAGCATtcgtttaataatgaaaaaggattagatttacaTATGAAGACAATACACAACCAAAATGCAGATGATGAATTAGGAAGTAATGAGCATAGTGATGAATGCAAAGACAATGACACGTTACAGGTGTCAGTTAAAAGAGAAATGATTGATGAAATTGACgtttcaattaataataatgacaaTGATAACgataatgatgatgatattGACAATACTATGgaggaaaattcaaatatggGCGATTCCATTCAGCCCAGTGATAATGACAATACAAATGGTGGTACACAATCGCCACCAAAACAACGTGAATGTCCGATTTGTAAATCGATTTTCAATGCCGGTGTATCATTTTCAAATCATATGCGAACTCATATGGTATCGTCACCGCACCAAAATTTTTTACGTACCCTAAATGTATCGGGCCAACCCATTGTAAAGCCATCACGAATGCGTTGTCGTTTGTGCCAAAAAAGAATCAATACCAAATTGGGACTGAAGCGACATATGCTGCTGGCACATCAAATACGTGATTATACTTGTGTTAAATGTTATATGTGTCCAGCTGAATTCAGCAGTCATAAAGGACTGAGGGTTCATTTATTGAAATCACATCAAATCGCTAAGGCTGAGGATGATGCAAATACGATGGATGGCGGcttaaaaatcaaaacggaaacgtcgataaataattttgaatgtcaTATTTGCCATATAGTGTACAAAAATAAAGATGATTTGAAACATCATTGTTCATCAGTACATGGATTTGAGCtGCCAACAGAAGACATTGACTCGAAAGATAATCTATTGGATGAAGACACGTTGAATGAAACAAAAGAAGACTCATTTGAAAGGGATTACTGGTATCAATGCCGTTATTGTGTGGACACTTTTAATTCTGGAAAACAATTGACTGTTCACATGAATACACATGAAGAACAATATCCTACTGATTATTCATGTAAAGATTGTGGAAATGTTTATAATACAAGGAAGTCACTGTGGGTTCATCGATATAATAAACATCCACGGCCGCCAAATCCGACCGTCTGCGAAATTTGCAAAAAGGTGTTCTTCGAtaaaacagaattattttatcatttaaaaacaCATTCACAGTCTAATACAAATGCCGCAAGTTTGcaatcgaatttaaaattttcatctcCATCAACTATAAATCAGCCAGGTAAATATGCATGTCACGTTTGTGGTCAGAAATTCCATGAAAAGGGTCCACTTAGCAAACATATTAAAATGCACGAATTGGAGAATAATTCGTTTGGCGGTAATCCTCTAATGTCAATGTTTGATGAAGGTGGTTCAACGAGTGGGGGAAATAACGGTAACGATTACGATAGCGGGAATGATATTAAGACACAGTTTCAAGAACAAATACGTATGGTGAATGGTGAATATGCTTGTGATTTATGTCCAAAAAcgtttccaattttaaatgcGCTTCATGTACATAGAGGATGGCATTTTCGATCACCGAGTGGCAGGCAAGTAACAGATCCTAGTCAAACCTGGCAGCCTGATAGTATTCCACCTTCAAAATTGCGACGAATGCGGAACCCATACGGCCAACCGCCTACGTGTCCATATTGTAGCTCAACGTTTGCCAGTACAAACAACCTTCGAAGACATATAGTCGAGGTCCATAAGCGGAATGAAGCAAAATTAATGCGTGAAAGTGCGAGTGATAATGCCGGGTTTTATGTTGAGAAAATAAAGGAATGTCGATCGTGTAACATGTCATTTAATACAACCACGGAATGGATtgatcataaaattatccaTGCGCGAAACCAAAAACCATCAACGACCTTCGAATGGGGCTGTGAAATATGTGGCAAAATGTTCACCCGCAAAGAACGACTACTGCAACATATGATAACACATTTAAATAGTCGGGAATTTGATGAGGATGGTAATTTTACTAATACCGGTGGTGACGGAACAAATGAAAATTCTATGGAACCATCGCAAATGGGTagtgaattaaattttgaaagtaatTCCCAAAGTTCACAGAGTTCAATGTCTTCGTCATCGAACGAACAAAATAATGAAGACCAAaatgatgataatgataattatgATCAGGATGAAATGATGTCTGAGCCGGATAATTCTGAACTTCCCGAAAGTTTATCTTGTGAGTTGTGTCAAAAAAGGTTTACATCTACTGCAACGCTTCGTGAGCATATATCAAATCATATTTTGAATGGTAATTTACAGTCAGATCCCACTGAATCTtctcaaaaatcaaatgaacaGGATATGCAACAatcttctaataatttttgtcaaatatcaaatatgttttaa
Protein Sequence: MDNSEITISNRQICCRLCLAPDNECVPIFTNSAADKEPLSSKIQACVNIKVHETDRLSSRICHYCISYLNSWQSFKNRCLAAQKKQRTLLFLLSEKQKFQRQHAATQAATIARRQLQHQLQRNLLNFVANKDGGSGIQNEVQDEDRNNATNQIKNNDVDLTCVKEEPQEMISDDEDQNNMNVELDPSQFLANNEDDDDYQAYDEREPVPAPIISMEEGPPILTSLGLTHVNHVNSCNFVKTEADYGDDLTNSGELYNSFNDQKLGGPIPGACSICDMKFSNRANARRHERNIHGILPNPLTFTPQISNPTTINPAAVKPVISRKVIHVPEVYNYETPEKYRPYLTENKIKFIRNNLTFLEQYQDMICACCDRQYQTYKAFMSHMRKKYQFLPRNLCFKCLKQFETKGQFIAHLKKRNCINLYKLYMIDESITKPELTEEEKARNKTKDILANKDYGCKLCGLTFKLKMDFRAHVFEQHADNQKGNDVALTICGFCNVKFEDAPTKKRHYTNLECIISIICGSCGEKFTQHPHYIDHVYTNHLSNANANDFNEADSYDGEFETSYQSTSRLRTPQNCAVCGKQYNNYYNVLRHMESKHPDQLPQTYSCEHCQTGFPRQSELREHIKLNHRDSLFRTPTSSANVSVSGGIKQSIISCNDCGLVCETRDIWIEHMTTHSKFVCPQCEYKTESKEEYNNHLSTHLKFKLYSCVICKHSFNNEKGLDLHMKTIHNQNADDELGSNEHSDECKDNDTLQVSVKREMIDEIDVSINNNDNDNDNDDDIDNTMEENSNMGDSIQPSDNDNTNGGTQSPPKQRECPICKSIFNAGVSFSNHMRTHMVSSPHQNFLRTLNVSGQPIVKPSRMRCRLCQKRINTKLGLKRHMLLAHQIRDYTCVKCYMCPAEFSSHKGLRVHLLKSHQIAKAEDDANTMDGGLKIKTETSINNFECHICHIVYKNKDDLKHHCSSVHGFELPTEDIDSKDNLLDEDTLNETKEDSFERDYWYQCRYCVDTFNSGKQLTVHMNTHEEQYPTDYSCKDCGNVYNTRKSLWVHRYNKHPRPPNPTVCEICKKVFFDKTELFYHLKTHSQSNTNAASLQSNLKFSSPSTINQPGKYACHVCGQKFHEKGPLSKHIKMHELENNSFGGNPLMSMFDEGGSTSGGNNGNDYDSGNDIKTQFQEQIRMVNGEYACDLCPKTFPILNALHVHRGWHFRSPSGRQVTDPSQTWQPDSIPPSKLRRMRNPYGQPPTCPYCSSTFASTNNLRRHIVEVHKRNEAKLMRESASDNAGFYVEKIKECRSCNMSFNTTTEWIDHKIIHARNQKPSTTFEWGCEICGKMFTRKERLLQHMITHLNSREFDEDGNFTNTGGDGTNENSMEPSQMGSELNFESNSQSSQSSMSSSSNEQNNEDQNDDNDNYDQDEMMSEPDNSELPESLSCELCQKRFTSTATLREHISNHILNGNLQSDPTESSQKSNEQDMQQSSNNFCQISNMF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460484;
90% Identity: iTF_01052503;
80% Identity: -