Basic Information

Insect: Tipula helvola
Gene Symbol: -
Assembly: GCA_963556165.1
Location: OY744481.1:386690910-386692768[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00013 0.047 16.9 0.6 1 23 118 140 118 140 0.97

2 14 0.00013 0.05 16.9 0.5 1 23 178 200 178 200 0.98

3 14 0.024 8.8 9.8 3.1 1 23 208 230 208 230 0.98

4 14 3.6e-05 0.014 18.7 0.8 1 23 239 262 239 262 0.97

5 14 2.5e-05 0.0092 19.2 0.6 1 23 303 325 303 325 0.99

6 14 0.38 1.4e+02 6.0 2.5 1 21 334 354 334 356 0.92

7 14 1.5e-05 0.0055 19.9 0.8 1 23 362 384 362 384 0.98

8 14 0.00046 0.17 15.2 3.8 1 23 390 412 390 412 0.97

9 14 1.7e-06 0.00062 22.9 1.5 3 23 425 445 424 445 0.99

10 14 3.2e-05 0.012 18.8 1.5 1 23 451 473 451 473 0.97

11 14 9.9e-06 0.0037 20.4 3.1 1 23 479 501 479 501 0.97

12 14 2.8e-07 0.0001 25.3 1.1 1 23 507 529 507 529 0.98

13 14 1.7e-06 0.00062 22.9 1.4 1 23 535 557 535 557 0.99

14 14 6.5e-05 0.024 17.9 0.4 1 23 563 585 563 585 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00013	0.047	16.9	0.6	1	23	118	140	118	140	0.97
2	14	0.00013	0.05	16.9	0.5	1	23	178	200	178	200	0.98
3	14	0.024	8.8	9.8	3.1	1	23	208	230	208	230	0.98
4	14	3.6e-05	0.014	18.7	0.8	1	23	239	262	239	262	0.97
5	14	2.5e-05	0.0092	19.2	0.6	1	23	303	325	303	325	0.99
6	14	0.38	1.4e+02	6.0	2.5	1	21	334	354	334	356	0.92
7	14	1.5e-05	0.0055	19.9	0.8	1	23	362	384	362	384	0.98
8	14	0.00046	0.17	15.2	3.8	1	23	390	412	390	412	0.97
9	14	1.7e-06	0.00062	22.9	1.5	3	23	425	445	424	445	0.99
10	14	3.2e-05	0.012	18.8	1.5	1	23	451	473	451	473	0.97
11	14	9.9e-06	0.0037	20.4	3.1	1	23	479	501	479	501	0.97
12	14	2.8e-07	0.0001	25.3	1.1	1	23	507	529	507	529	0.98
13	14	1.7e-06	0.00062	22.9	1.4	1	23	535	557	535	557	0.99
14	14	6.5e-05	0.024	17.9	0.4	1	23	563	585	563	585	0.99

Sequence Information

Coding Sequence: ATGAGCAGTATAATAGTAGACGAACAAGGCCTGAATTTCCAAAGCATATGCCGCTTGTGTTTAAAAACCCATGAAGTGTTCCAATCGATTTTCGACTATATAGAAAGTGGTGTGAAGTACTCGGACATTATTGTCTTGTTTGCCCCAATCGCAATTCATGTAAATGATGGCTTGCCGCATAAAATATGCAATAATTGTGCACACAGCCtaaatctattaaataatttgcgAAGTGTCTGTGTTAAATCGGATACATGGTTACGGGAAAAAGCCGATAGAAAAATCAAGCAGGAACTCGTAGTGCCATCATCAAACGAAAATGACACCACCATCCTAGACGACCTACAACAATATAAGTGTGAACAGTGCGATGAGATATTTGCGAACGAAGACTGCCTTGAGGTGCACACAAAAGATCATGCCAATGAATCTCAAATTTATAACGATGGGCCTCATCACAATGATGCCGATGATATCGACAGCGATGATATTCCACTGATTCAATGCAAGAAAAATGGTAAACGACAAATTTATACTTGCGCTGTTTGTAATAAAGAATTTCCGAGTCGACATGCTGTAACTCGGCATGCGAATGTGCACAACAATGCTAAGGGGAAAAAATTTAAGTGTGAGGTGTGCCATATTTACTTAATGACACGACGAACGCTTCTACGGCATCGGAAGATTCACTTAAAGCCTGAATCGGATAAACAATACGCGTGTAAACAATGCGAtggtaaaacttttaaaaatcaaaaatcatacgCAGCCCATATGCGGGTACATAAAATTTACTACGAGACCAAAGAGAACCCGACGGACAGTGAGCAGGATGAGGAGCAAAGCAGTGACgaagaaatgaatgaaatggaTAAACCATCTAAAACGAAACAACTAAAAAGTGTATTTAAGTGTAAAGATTGTTTCCGGGTGTTTGAGAAACAACCGTCTCTTGCCTCGCACGTTCGCGTCCACAAAGAGAATATCACCAAGAAGGAATACATTTGTGACATATGCAATCAAAAATTCATCGCATATTTATTCCTAAAGAGGCATTGGAAATGCCATCCAGAGAAAAAAATCCACAAATGTAGTATGTGCAACGAAGCCTTTGTTTCGAGTGACCAACTGGCGGACCACCTTAATAAACATAACGATGTACGGCCGTATGAGTGTGACAAGTgcgataaaaaatttcattcagaCGAAACGTTACGCAAACATCGTTACGTTCataaaccaaattataaaaaaagtaaaatcgaaCGACTTTGTCCACATTGTGGCAAAGTGTTCAGCAACAATACGGTATTGCGACAACATTTGAATACCCATTCGGATACCAAACCTTTTGCATGTGATCAGTGTCCTAGTCGTTTCGTCTCAAAGCGATACCTAAAGAAGCACATTAAAACGCATGCTCGCTTAAAACCGCATATTTGTGAGGAATGTGGTCATGCATTTTCCAAGAAATCATCATTAGTTAAACATAAGCGTATACACACGGGTGAAAAGCCGTACTCGTGTGCAACTTGTGAAAAACGATTTAATTCATCAGAGAATTTAAAACGGCATATACGGATTCATACCGGGGAAAAGCCTTACAAATGTAAATTCTGTGATCGCGCTTTTGCACAAAGCAGTGAATTGACTGGACATACGCGTAAACATTTAGGCGATAATATATATCAATGTGAAGAGTGTCCGGCTGCGTTTCGATTGCACGGAGAACTAAGAGAACATACACGAATGCATTTTCTAGAAAGGAAGGAATCCAAAGAGGCGACTAatgaaatgatttaa
Protein Sequence: MSSIIVDEQGLNFQSICRLCLKTHEVFQSIFDYIESGVKYSDIIVLFAPIAIHVNDGLPHKICNNCAHSLNLLNNLRSVCVKSDTWLREKADRKIKQELVVPSSNENDTTILDDLQQYKCEQCDEIFANEDCLEVHTKDHANESQIYNDGPHHNDADDIDSDDIPLIQCKKNGKRQIYTCAVCNKEFPSRHAVTRHANVHNNAKGKKFKCEVCHIYLMTRRTLLRHRKIHLKPESDKQYACKQCDGKTFKNQKSYAAHMRVHKIYYETKENPTDSEQDEEQSSDEEMNEMDKPSKTKQLKSVFKCKDCFRVFEKQPSLASHVRVHKENITKKEYICDICNQKFIAYLFLKRHWKCHPEKKIHKCSMCNEAFVSSDQLADHLNKHNDVRPYECDKCDKKFHSDETLRKHRYVHKPNYKKSKIERLCPHCGKVFSNNTVLRQHLNTHSDTKPFACDQCPSRFVSKRYLKKHIKTHARLKPHICEECGHAFSKKSSLVKHKRIHTGEKPYSCATCEKRFNSSENLKRHIRIHTGEKPYKCKFCDRAFAQSSELTGHTRKHLGDNIYQCEECPAAFRLHGELREHTRMHFLERKESKEATNEMI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01458854; iTF_01460475;
90% Identity: iTF_01460475;
80% Identity: -