Thel045761.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula helvola
Gene Symbol
-
Assembly
GCA_963556165.1
Location
OY744481.1:390356909-390360186[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 6.5e-05 0.024 17.9 0.5 1 23 248 270 248 270 0.98
2 13 9.6e-05 0.036 17.3 1.5 2 23 277 298 276 298 0.96
3 13 5.6e-05 0.021 18.1 0.1 3 23 305 325 305 325 0.99
4 13 0.00018 0.066 16.5 0.6 3 23 357 377 356 377 0.97
5 13 0.00032 0.12 15.7 0.4 1 23 463 486 463 486 0.95
6 13 0.0063 2.3 11.6 0.2 1 21 493 513 493 514 0.91
7 13 6.5e-05 0.024 17.9 4.3 1 23 581 603 581 603 0.98
8 13 3.6e-08 1.3e-05 28.1 2.2 1 23 610 632 610 632 0.98
9 13 1e-07 3.7e-05 26.7 1.7 3 23 644 664 642 664 0.96
10 13 2.6e-05 0.0095 19.1 2.8 1 23 670 692 670 692 0.99
11 13 1.3e-06 0.00049 23.2 2.2 3 23 700 720 698 720 0.97
12 13 4.3e-07 0.00016 24.7 3.1 1 23 726 748 726 748 0.99
13 13 0.0016 0.59 13.5 0.1 1 23 754 776 754 776 0.98

Sequence Information

Coding Sequence
ATGGatgaaaatatatcaaatagtttagaatataatttaaatcgGATATGTAGATTATGTTTGAACGAGTATGATGAGCTCAAATCAATATTCCAATTGAGTGAATATTATAATTCACAGCCATTGCATGAGATCATTATGGCTTGTGCCCAAATCCAGATTGTTGAAGATGATGGATTGCCAAATGGAATTTGTAGTGGCTGTGTGAGACAAGTGAATATGGCTTATGAATTCAAATTAAGATGTGAACAAAGTGATAATAAGCTCCGATCgtatataataagaaaatatcCTACTAGAAATATTAAGTTTGCAATCTCTGAATCGTCTTCGAGCTATATTAAAGAAGAAGATCAAGACTATTCGTTAGGTGCTGTTATTAAACCAGAAATATCGATTATAGAAGGTGATCCTTTAAATGGAAATTTCTATACGAGTAATGGACGTGAATTCAACGccataaatcaatttaataatcaacaTAGTGTAGATAATGTTGAACAGATAAATGGAATTCAGAATGAAATGTGTGGTATACAGCAGCAGCAAAGTACATCATGCGATGATGATTCAAATAATGATTTCAACGATGATCTGTTAAATGATGATGAGGACgacgacgatgatgatgatgaacagGTTAAAAAGGACGAACTATCGATCTATATAAAAAATGATCCAGATtccgattttaatgaagatAAATTTGATTATCAGTCAGCACGTAATGAACAAGGCAGGTACAGTTGTCATATATGTGAAAAGACTTTGGTTGATGCCAAAGGGTTGAAACTGCATATTCGTCTTCACACGGGAAACAAATTGAAACGATGCGATATTTGCAATAGAGgatttGCTAAACAAAATCACTTGAATCGTCATTTGGTCATTCATAAGGGTAAACCAATCGGCTGTGACGAATGTGGTCTATCGTTTCCATCGCTtagtgaattaaaaattcatgtgCTTACTCACAGTGGTACAAATATAAAaaaacaagTTAAAGCCAGTTATAATGAAAATCGGGAAAGCGATATAAATGATAATTCACCAGAAAAATATGCACTGTGTAAAATATGTGACACAACGTTTACACAAATTAAATCACTCAAAATACATTTGCAAGCCCATATAGATGTGAattcatttcaaaatgtgaatttgcaTACAAAACTTTTTCTATtcgatttaacaaaaattacacCAAATATCGAAGATCATGATACCCTAATAAAATACGTTATTAATGATataaaagctaacattttaGCACGATTTTATCAAATAACAAATCGAAATGGTTACGAATATCAATTATCTGATTCTGAATCGGAAAATGACGAAGAAATGCATGAAATGAATGCGGACCGTATTACAAATATTCAACATGAATGTCCCGAGTGTGATAGCATCTTTAATCGatcgtataaattaaatttacatttagaaATAGAACACGGTGATTATCAAAATCCGTTCGTCTGTATTGATTGTGGCCGAAGATTTCCGACCGAATGGTTACTGAATCGGCATTTTAAACGccaatgtaataataaattgaaacaatattcgtgtagtttatgtaaatttaaatttatgtggcaGTACAGTTACGAGTTGCATAATGAGAAGTTTCATTcgggcaaaaaaataaaacgttctACAATTGCGTCTTCGTTAGATTTACTAACGGATGATAGAAAATCAAGATCATTGAaagaaaaaccaaaagaaaaaaattttaggtGTGGTACGTGTAGCAAATCTTTTTATCGACAAGAGCATTTGGATCGACATACTAAAATCCATATCCCATCAGAAAAGAAATTTGAATGTACAATTTGTCAGAAAAAGTTTAACCGCAAGGATAATTTACGGTCGCACATGAGGGTGCACCGAGATGATAAAGAAGACACGGATAAACATCTATGTGTTTATTGTGGTAGAAGTTTctcaaattcatcaaatttaatagTTCATATGCGACGCCATACTGGAGAAAAACCATACAAATGTGATTTATGTGATAAAGGTTTCCCTCGATCATCTGATTTGCAATGCCATCGAAGAACACACACAGGGGAAAAGCCTTGCCTTTGTACAATTTGTGGTAAAGGATTTTCTAGATCAAACAAACTTGTACGACATATGCGCATTCATACAGGCGTTCGGCCCTATAAATGTACGCATTGTGATCGAGCTTTTACACAATCAAATGATTTAACGCTTCACATAAGGCGACATACTGGAGAAAAACCCTACGTATGTGGAATATGTGGTGATCGGTTTATTCAGGGAACTGCTCTTCAAACGCATCGAAGAGTGCACGGTCATTATGAGGAAAATCAACCAGCACCTTATGCAAGTATCAGTGTAAATAATCCTAATCGGTATACAAACGCAAATCGAGTTAATCGCATTGGATTCATTGCACCAGTTACTGCGACAACGGCATCAACATCAAATTCTGTTATAAAGCCAATTATATCAAGGCGTTCCAcaccaaattcaacatttttaactCGTTCTACTACAACAGCGCCATCCATAATCACAGAGGAGTCTTCTCCAAATCTGATTgagcaacagcaacaacaaattaattcaacaatGCCAGTAAATCCAATAAATGTTGCACATTTACCGCGTTCTCAATTATCTGATTCGGCAACTCCTACTCCTATTGGAGATCCCCTACAACCTACTAATTTAGTTGGAAACACGAATGCTAATAATCTCCATAATATGCCACCCATACTACCATCACCTCATCCTACATCACAGACATCACAGCGAATGCTACCAAATATTGGATTCCCATATGCTCCAAATctagaaatatttacaattttagaaatgtaa
Protein Sequence
MDENISNSLEYNLNRICRLCLNEYDELKSIFQLSEYYNSQPLHEIIMACAQIQIVEDDGLPNGICSGCVRQVNMAYEFKLRCEQSDNKLRSYIIRKYPTRNIKFAISESSSSYIKEEDQDYSLGAVIKPEISIIEGDPLNGNFYTSNGREFNAINQFNNQHSVDNVEQINGIQNEMCGIQQQQSTSCDDDSNNDFNDDLLNDDEDDDDDDDEQVKKDELSIYIKNDPDSDFNEDKFDYQSARNEQGRYSCHICEKTLVDAKGLKLHIRLHTGNKLKRCDICNRGFAKQNHLNRHLVIHKGKPIGCDECGLSFPSLSELKIHVLTHSGTNIKKQVKASYNENRESDINDNSPEKYALCKICDTTFTQIKSLKIHLQAHIDVNSFQNVNLHTKLFLFDLTKITPNIEDHDTLIKYVINDIKANILARFYQITNRNGYEYQLSDSESENDEEMHEMNADRITNIQHECPECDSIFNRSYKLNLHLEIEHGDYQNPFVCIDCGRRFPTEWLLNRHFKRQCNNKLKQYSCSLCKFKFMWQYSYELHNEKFHSGKKIKRSTIASSLDLLTDDRKSRSLKEKPKEKNFRCGTCSKSFYRQEHLDRHTKIHIPSEKKFECTICQKKFNRKDNLRSHMRVHRDDKEDTDKHLCVYCGRSFSNSSNLIVHMRRHTGEKPYKCDLCDKGFPRSSDLQCHRRTHTGEKPCLCTICGKGFSRSNKLVRHMRIHTGVRPYKCTHCDRAFTQSNDLTLHIRRHTGEKPYVCGICGDRFIQGTALQTHRRVHGHYEENQPAPYASISVNNPNRYTNANRVNRIGFIAPVTATTASTSNSVIKPIISRRSTPNSTFLTRSTTTAPSIITEESSPNLIEQQQQQINSTMPVNPINVAHLPRSQLSDSATPTPIGDPLQPTNLVGNTNANNLHNMPPILPSPHPTSQTSQRMLPNIGFPYAPNLEIFTILEM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01455062;
90% Identity
iTF_01460471;
80% Identity
-