Tcon014120.1
Basic Information
- Insect
- Tipula confusa
- Gene Symbol
- topi
- Assembly
- GCA_963556175.1
- Location
- OY744475.1:190849748-190851852[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 1.2e-06 0.00018 23.1 0.8 1 23 187 209 187 209 0.98 2 9 0.0031 0.46 12.3 0.5 2 23 229 251 228 251 0.94 3 9 0.00096 0.14 13.9 1.4 1 23 319 341 319 341 0.99 4 9 0.011 1.6 10.7 0.7 1 21 387 407 387 411 0.88 5 9 1.1e-06 0.00017 23.2 2.0 1 23 470 492 470 492 0.95 6 9 0.004 0.6 12.0 1.0 1 23 498 523 498 523 0.95 7 9 0.054 8.1 8.4 0.7 1 23 529 551 529 551 0.89 8 9 7.7e-07 0.00011 23.7 0.2 3 23 559 579 557 579 0.98 9 9 0.00012 0.018 16.8 0.6 1 23 585 608 585 608 0.96
Sequence Information
- Coding Sequence
- ATGAACATCTTAAACAGTGaactaaacgaaaatattttaatcgatcTAAATAGTTTGGCACTATCTACAGACGAAGACGATGATCGTGGTGACAATCAAATACCGGaagaaacaaatacaaaaatttcgaaTGAATCTGAAAATGTAGTCGAAGTTGCGGATGAAATAAGTTGGGATCAAATAATTCAATTGGCCCAAGATAGAACGAATGACGTGTATTTGATGCCAGACGATAATAATCATCAAGATATATTCACACTTTTAAAAATGGAAGGAAAAGAATTGCCATcggaCCAAACAATTATAATTGAGGTGATAAACTACAGTGACAATATTCCGAATGCTATGGAGGAGGGTCCAAAGAGTGATGATAATATGTTAGTGAAAGAAACGAAATTACATCAACCCGTTACGATAAATCAAGAAGAGTCCCTATTGAAAATGCTTAATTCGCCTTGTTTCAAACAGCTTAAAGACAATAATATcaaattgcaaacatttttaaaggaACAAGCCAAAATTGACttaaaaattcacaataaaaAAGGCGATGGCCCATTTGAATGTAATCTATGTGAACGAGTATTTGTGCATGCTTCGGGCTTGAATCGTCACATGGAAAAGCATACCAGTGAATATATACCAaattctaatataaaatatgtaccaTATCAGTCGATTGTAAAGTGTATGGTATGCGGAAGAATATTCGCCAATAACCATTCAGCGCTGGATCACATGAAATTTGATCATCAAGCTGAATATCGTACGGAAATTCACTATTCAGAGCTAGAAAAGTTCGACGATTATGTTGTACCCGAATGTAGTAGCACATCGGATAGCTATCCAGacgatttaattataataaatgagCTCATAAGAAGGGAATCTTTAATCCCAGGCCCCGATGAGAGAACCGGTAAAATGTTCGATGTCATAATTTTGAGTTGCGTTTTTCAATGTGAATTCTGTGACTATCTGTTTGGTGATGTGGCACAATTAATGCACCATCAAAAGTCGCATGATCCGTTGAATGGATACGAATGTCGATCAtgcgatatttttgttgatacattAAAAGGGATACTGTTACATTGGCAAATTGAATGTATTTATCAGAGTGATCAATTTTACGGTTCGATAAAACTTCAACGGTATTATCTCTGCAATATTTgctttgaaacatttaaaaccaTTGACCTCCTTTACAGTCATCGataTGTGAATTCGCATTTATTTCCACGAGTTTGTCACTCGACGggaaaattaaaagtgatttgTGAAATATGCGGCAGTGTGCACGAGTCGGCCAAATCAATGGTCGATCATTATAATCAAAAGCATGTAACagtaaaaaaaacgagtaaaaAAGTGAGTAAGCCTGAACCGATAGTTCGAAGCCGCCAATTTTTGTGTGATGTTTGCGGTAAATCATATACGCAATCAAGCCATTTGTGGCAACATTTAAGATTTCATCGAGGCGTTAAGCCATTTGCATGCAGTGTCGAAGGATGTACGAGAAAATTTACGATAAGACCCGATTTAAATGATCACATTCGAAAATGCCATACTGGTGAACGGCCATATCAATGTCTTGTGTGCGGAAAACGATTTCTCACTGGCTCGGTATTTTATCAGCATCGGCTTATACATCGCGGTGAACGTCGCTATGGGTGTGAACAATGTGGCAAACGATTTTATCGAGCCGATGCGCTTAAAAACCATATAAGGATACATACGGGCGAAAAACCATATCCGTGCGAATACTGTTCAAAAGCTTTTCGACAGCGCGGCGATAAAGACAAACATATTCGGGCTCGACACTACGcatttatcaacaaaaatatggtAAAACCGAACGCCGTTAAATTTCCGATTAAGAATCATGTCCAAAATAAAGTGGTTTATGTTGGCGATGTTGCATTTCCCCAAAGCATGTTTCAACCGATGATTCGTGATATAGACTCGATTGATTtgagttaa
- Protein Sequence
- MNILNSELNENILIDLNSLALSTDEDDDRGDNQIPEETNTKISNESENVVEVADEISWDQIIQLAQDRTNDVYLMPDDNNHQDIFTLLKMEGKELPSDQTIIIEVINYSDNIPNAMEEGPKSDDNMLVKETKLHQPVTINQEESLLKMLNSPCFKQLKDNNIKLQTFLKEQAKIDLKIHNKKGDGPFECNLCERVFVHASGLNRHMEKHTSEYIPNSNIKYVPYQSIVKCMVCGRIFANNHSALDHMKFDHQAEYRTEIHYSELEKFDDYVVPECSSTSDSYPDDLIIINELIRRESLIPGPDERTGKMFDVIILSCVFQCEFCDYLFGDVAQLMHHQKSHDPLNGYECRSCDIFVDTLKGILLHWQIECIYQSDQFYGSIKLQRYYLCNICFETFKTIDLLYSHRYVNSHLFPRVCHSTGKLKVICEICGSVHESAKSMVDHYNQKHVTVKKTSKKVSKPEPIVRSRQFLCDVCGKSYTQSSHLWQHLRFHRGVKPFACSVEGCTRKFTIRPDLNDHIRKCHTGERPYQCLVCGKRFLTGSVFYQHRLIHRGERRYGCEQCGKRFYRADALKNHIRIHTGEKPYPCEYCSKAFRQRGDKDKHIRARHYAFINKNMVKPNAVKFPIKNHVQNKVVYVGDVAFPQSMFQPMIRDIDSIDLS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01456764;
- 90% Identity
- -
- 80% Identity
- -