Tcon021437.1
Basic Information
- Insect
- Tipula confusa
- Gene Symbol
- Lztr1
- Assembly
- GCA_963556175.1
- Location
- OY744476.1:108620987-108626183[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 8.1e-15 4.1e-12 47.6 0.1 1 107 370 501 370 504 0.84 2 4 3.8 1.9e+03 0.3 0.0 76 108 502 534 501 536 0.88 3 4 3.2e-18 1.6e-15 58.5 0.0 8 106 599 699 595 703 0.85 4 4 1.3 6.6e+02 1.8 0.0 76 100 701 725 695 733 0.85
Sequence Information
- Coding Sequence
- ATGTTGTCTCAGAGTGGGTCATCTTGTGTTCTAAAATATAAAGACTACAAGGGATCATCGATTTCGACGCGAGATTCTACTTATCATGCACTAACATTGGATTTGGCTCCTTTTGAAACCGTCCACCAATGGAAACGTATGCTGGAGTGTGATGAGTTTGTGGGTGCTCGTCGTAGCAAACATACGGTAGTGGCATTCCGAGATgcaatttatgtatttggtgGAGATAATGGCAAAAGCATGTTAAATGATTTGATTCGTTTCGATGTAAAAGATAAATCGTGGGCTCGATCATTTTCTACCGGAATACCGCCAGCTCCAAGATATCATCATTCGGCTGTTGTTCAtggaaattcaatatttatatttggtgGCTACACGGGTGACATTCATTCTAATTCAAACCttactaataaaaatgatttattcgaGTATAACTTTCATACGGCACAATGGGTTGAATGGAAATTTGTAGGACGAACTCCAGCTCCTCGATCTGCCCACGGAGCAGCGGTATACGATAACAAACTTTGGATTTATGCTGGTTATGATGGAAATGTACGACTGAATGATATGTGGACTATTTCTCTTACCGGCGATTTGAAACAATGGGAAGAAATTGAGCAAAAAGGTGATAGACCACCAACATGTTGTAATTTTCCGGTAGCAGTTGCGCGTGAATGTATGTACGTTTTTTCCGGACAGAGTGGACTTCAAATCACCAATACATTATTTGAATTCAACTTTCAAGAAAAAAATTGGCGCCGAATATCAAATGAGCATATCTTACGTGGAGCGCCACCTCCTCCAGCAAGACGTTATGGCCATACAATGGTGCATCACGATCGTTTTCTGTATGTTTTTGGAGGTTCAGCTGATTCCACTCTGCCAAATGATCTTCATTGCTATGACCTTGATTCACAAATTTGGTCCATTATTGTGCCGGCCGTCGATTCACAAATACCTTCGGGACGAGTTTATCACGCATCTGCAGTAATCGGTGATGCAATGTACATTTTTGGTGGTACCGTTGACAATAATGTTCGTAGTGGTGATATGTATCGATTCCAATTTTCAAGCTATCCAAGATGTACACTACAtgaagattttggaaaattttttactaGCCGACAATTTTGCGACGTTCAATTTATTGTAGGCGAACAGGAACTTAAAATTCCAGCCCATATTGCCATAATTGCAGCACGATCAGAATATTTAAGGGGCAAGATATTATCCGCTCGAGAAGCAATGAATAagcatttggaaaaattatttgggaCAGCTGAAGTGCCGTTTGATCAACATCCCCTGCTTGAGGTAAAACTTCCTAACGTGAATAGTGAGGCGTTCGAATTGGTgttatattacatttataatgatCGCATAGAATTTCGTGACCCGTTTAGCGCCAATCTGGTGGTTTTTATGATGGACGTCTATCAGCtagctgttgaattttttatgcCACGATTGGAGCAACTCTGTGTTCAGTATTTAGAgtttaaaatatcaaagaaaaatgttttggatgCCCTGTACAATTCTGATAAAAtgcaatTAGCACGAATTAAAGAATATTGTCTTGGATATATTATTAAAGATGATAATTTCTCGGATATCGTGATGTCAAACGAATTTGTAGGATTGGAAAAATCTTTAATGGTCGATGTAATAAGACGACGACTGAATCCGGCCAAAACAGGAAATGAGCTTAAATGTGAAAAAGCTTTGTCCAATAGTAATGGATGCACGTTAGAAAGTGATATGGCCGTATTTCTCATTACAACAGGGCATGAGttttgtgatataaatttaattctcgaTGGTATTGTCATTCCCGCTCATAAAACTGTTCTTGCTGCGAGATGTACATATTTTCAAGCATTATTTCGATCGTTTATGCCCCCTGATCGAACGGTGAACatccAGATCGGTGACATTTCACCATCGCGTGAAGCTTTTGATTCCCTTCTACGATACATATATTACGGTGACACAAAAATGCCGGCTGAAGATTCGCTTTATTTGTTTCAAGCTTCCTGTTTTTATGGATTCTCAAACAATCGATTACAAGCATTTTGTAAACACAATCTAGAAAATAATATAAGCCATGAGAATGTCTTACAGATTCTTGAAGCTGCTGATAACATGAATGTACCTGATATTAAAAGTTATGCACTCCGAATGATTGCACATGATTTTCAACGTGTTAAGGACCAACCAaaattagtttcgttaagtaaaCCACTGGTACATGATGTGCTCCTAGCCATGGTTCCATCGTCCGTATTATTATGCTCTAAAAGGAATTTCTATACGCATATTcctttttataataaagaaatCGTTGAAgataaaaacaaaccaacaacaTCGGGGGGAACAACGACATCAACGTTAGAAAtaggaaaaaatggaaaattaatagtGAAAAATGTTGAAGTTTTCGATAATGTAACAAAAGATGTGATAAATACAGTTGATAATAGTGAACTGTTGGCCGATGGACTTAAACCGATTGGTGGTAAAAAGCCAGTTGATGAAAAATTGCAAGTGAAGCAAGTAAAGAAAAAAAGTCGAGTGGATTTTAATAGGTCGTCTCTTGAACGCAATTTTATAACACCGGCTCGTGCATTGGCTGAATTTCAATTAAAGCTCTCGGATATAGAAAAACTTCCAAAAACCAAACGACGTTCACCATATGAGCAAGAACCACCAATCGATGTGTACTGGCGCAAAGATGTTGAAACTAAAGCCATAGAAGTTTGGGGATCACGAGAACGTATCGTACAAGAATGTTTGAAACGTGAAATTGAACGTAGGAAACATcagcaaaatatatttacggTGAAACGGCGACTGCGTGATTATCGACGGGAAATCGGAAGTCGGACGACCGTAGTTGACAGTGAACCGGGATTAATGGGGAAATCCGGTCGCGTCGTCCTCACTGCAATCGTTATTAACGCGACcaatttagtatttaaatttggtGCTTGGATTTATACTGGATCGCATAGTATGTTTGCTGAATGCATTCATTCACTTGCGGACACAATAAATCAATGTATTTTGGCGTATGGAATTCATAAATCTACCCAAACAGCTGATTCCGACCATCCATATGGCTATGCAAATATGAGATATGTCTCATCATTGATTTCAGGATGTGGCATTTTTTGTATAGGAACTGGATTATCGTTTTATCATGGAATTGTTGGTTTAATAAATCCAGCGCCAATCGAAGATTTTTTTtgggcattttttattttaggcgGATCATTTATTTCGGAAGGTGCTACATTACTAGTTGCTGTGAATGCAATAAAAAGTGCTGCGGCCAAAAATAATGTTACCTTTAAAGAGTATGTATTACGAGGACAAGATCCTTGTGTAAACGTTGTGCTAGCTGAAGATGCCGCGGCTGTTCTTAGTGTTGCACTTGCTGCCGGATGTATGGGACTCTCAACATTTACTGGCTCGTCTATACCGGATGCAGTTGGTTCGCTTCTTGTTGGTGGAATGCTAGGTGTTGTCGCCTCATTCATCATTTACACGAATGGTACTGCTCTAGTAGGTCGTTCAATACCACAAGAGAATCTCGATAGAATAAATTCCGAACTCGAAAGTGATATTATGATAAGAGCCATCCATGATGTTAAAGGTATTGACATTGGAAATTCGTTGGTACGGTATAAAGCTGAAATCGATTTCGATGGTCGCGAATTATCGCGTTTATATTTAGAAAAGCAAGATATCAATAAAATgcttgaagaaattaaatattttaccacaTCGGAGGAGCTCGAAGCGTACATGTTAAATCATGGCGAGAATATTGTCGATTTGATGGGTGGTGAAATTGACCGTATCGAAATGAAGTTACGAAAGAAATTTCCAGAAATTCGTCATGttgatttagaaattttgtaa
- Protein Sequence
- MLSQSGSSCVLKYKDYKGSSISTRDSTYHALTLDLAPFETVHQWKRMLECDEFVGARRSKHTVVAFRDAIYVFGGDNGKSMLNDLIRFDVKDKSWARSFSTGIPPAPRYHHSAVVHGNSIFIFGGYTGDIHSNSNLTNKNDLFEYNFHTAQWVEWKFVGRTPAPRSAHGAAVYDNKLWIYAGYDGNVRLNDMWTISLTGDLKQWEEIEQKGDRPPTCCNFPVAVARECMYVFSGQSGLQITNTLFEFNFQEKNWRRISNEHILRGAPPPPARRYGHTMVHHDRFLYVFGGSADSTLPNDLHCYDLDSQIWSIIVPAVDSQIPSGRVYHASAVIGDAMYIFGGTVDNNVRSGDMYRFQFSSYPRCTLHEDFGKFFTSRQFCDVQFIVGEQELKIPAHIAIIAARSEYLRGKILSAREAMNKHLEKLFGTAEVPFDQHPLLEVKLPNVNSEAFELVLYYIYNDRIEFRDPFSANLVVFMMDVYQLAVEFFMPRLEQLCVQYLEFKISKKNVLDALYNSDKMQLARIKEYCLGYIIKDDNFSDIVMSNEFVGLEKSLMVDVIRRRLNPAKTGNELKCEKALSNSNGCTLESDMAVFLITTGHEFCDINLILDGIVIPAHKTVLAARCTYFQALFRSFMPPDRTVNIQIGDISPSREAFDSLLRYIYYGDTKMPAEDSLYLFQASCFYGFSNNRLQAFCKHNLENNISHENVLQILEAADNMNVPDIKSYALRMIAHDFQRVKDQPKLVSLSKPLVHDVLLAMVPSSVLLCSKRNFYTHIPFYNKEIVEDKNKPTTSGGTTTSTLEIGKNGKLIVKNVEVFDNVTKDVINTVDNSELLADGLKPIGGKKPVDEKLQVKQVKKKSRVDFNRSSLERNFITPARALAEFQLKLSDIEKLPKTKRRSPYEQEPPIDVYWRKDVETKAIEVWGSRERIVQECLKREIERRKHQQNIFTVKRRLRDYRREIGSRTTVVDSEPGLMGKSGRVVLTAIVINATNLVFKFGAWIYTGSHSMFAECIHSLADTINQCILAYGIHKSTQTADSDHPYGYANMRYVSSLISGCGIFCIGTGLSFYHGIVGLINPAPIEDFFWAFFILGGSFISEGATLLVAVNAIKSAAAKNNVTFKEYVLRGQDPCVNVVLAEDAAAVLSVALAAGCMGLSTFTGSSIPDAVGSLLVGGMLGVVASFIIYTNGTALVGRSIPQENLDRINSELESDIMIRAIHDVKGIDIGNSLVRYKAEIDFDGRELSRLYLEKQDINKMLEEIKYFTTSEELEAYMLNHGENIVDLMGGEIDRIEMKLRKKFPEIRHVDLEIL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01458505; iTF_01456120;
- 90% Identity
- iTF_01456120;
- 80% Identity
- -