Tcon005480.2
Basic Information
- Insect
- Tipula confusa
- Gene Symbol
- Hr39
- Assembly
- GCA_963556175.1
- Location
- OY744475.1:62884965-62896354[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 5 0.34 5.3e+03 -2.2 1.5 98 171 133 203 80 228 0.43 2 5 3 4.6e+04 -9.7 13.3 61 150 183 298 142 333 0.49 3 5 4.2e-09 6.5e-05 23.9 0.0 1 31 430 460 430 473 0.85 4 5 8.6e-05 1.3 9.7 0.0 76 140 473 538 454 545 0.70 5 5 4.1e-76 6.3e-72 244.6 0.9 202 408 548 747 537 747 0.98
Sequence Information
- Coding Sequence
- atggCCACTACGGGTAGTACCAATAGTAATAGTGGCAGCAATAATTGCACGATTAGCAGTAGTAGCAGCAGCAGTTGTGGGCCACCGACTTCGAGAGGCAACGTATCCGTAACAAGTATTAATTGCAGTGATGATAGTGGAATACAATCCCAAAGTTCTCAGGCAAATGGATCAATATTAACAAATGGTGGGGCaacacatttttatgaaaatggtgGAATTCGAATTTCTGTGCCAAAAATGGAGGAATCAGATGAGTCTGATACCGAATTGACAAATATTGAGAATAATTCAAATAGCAATGTTGGAATGCGAGAAaatcgtaataaaaatattccacGACCGATGAGTTGGGAGGGAGAACTATCGGAAAACGAGGATAGTAATATGATGATTGTGGAAAATGGTGAAACGAGTAATTTATCAGCTACCACAATTCAAACAACGTCGACAAATACGGTTACAACAACCGATGAACCGATTAATTTACACCAATTGCCAAAAGAATTTAAGCCTGAGTTTTTAGATAACAATAGCACATCGAATTTAACAACAACGTCGTCGTCTGcaacaacatatttaaatttaaatagtaaaaaatttccggagtatattaatttaaaaaatgaaactggTGTTCATGACGTAATTAGTTCTCCGCTACTAGCTAGATCTAAATCAAATTTACTTCCAGCTAATCCAAGTCCAGATTCCGCAATACATTCTATTTACACACATAGTTCACCGTCCCAATCTCCTTTAACGTCCCGACATACTCCATACACTCCCTCACTGAGTCGAAACAATAGTGACGCGTCACATAGTAGCTGTTATTCATATAGTTCAGAATTTAGTCCAACACATTCCCCCATACAAAGTCGCCACTATTTATATGGACCAAATGCTGCGCAATCTGGTCTTACAAATTCACCTGCACATCATTCTCTGCTCTACCGTCCTATGTTAGATAGTGAACAAAGTACATCGTCGAAATTTTTACAGCCGAAAGAAGAGGGCGTACTTGAAGGTGAAGCAATTCCATCGCCCGGTATTTCACGACAGCAATTAATAAATAGTCCATGTCCAATATGTGGTGATAAAATATCAGGCTTCCATTATGGTATTTTTTCATGTGAATCATGCAAAGGATTTTTTAAGCGTACcgtacaaaatagaaaaaactatGTATGTTTGCGGGGAGCGGCATGTCCTGTTACAATAGCAACACGAAAAAAATGTCCTGCCTGTCGATTTGAAAAGTGTCTGCAAAAGGGTATGAAATTAGAAGCGATACGTGAAGATCGGACACGTGGTGGTCGATCGACATATCAATGTTCGTATACACTACCCGGATCAATGCTTAGTCCATCGATTAGTTCCGAATCATCAGCGAATTTATATTATAGTCAAAGACTTTCCACCAACGGATTATTAAAAGTTGAAACGCCTGAATCGAGTTCAAGTACATCGACATTTAATAGTAACATAAAACTAGAAATTCCACCACTTTTGCAAGATATTATGGATGTTGAACATTTGTGGCACTACAATGATGCTGAATTAGTTCGTTTAAATCAGCCAGCACCAACGAATCAATCAACAAATGTTACATCAAATCCATTATTAGCTAGCGCCGGACTATCGAAAAGTGATAATCCCGATTTAATTGCTAATTTATGTAATGTGGCCGATCATCGTCTATATAAAATAGTGAAATGGTGTAAAAGCttacctttatttaaaaatatatcgATTGATGATCAAATATGTTTGCTTATAAATTCATGgtgtgaattattattattttcatgttgTTTTCGATCAATGTCCACTCCTGGTGAGATTAGAATATCGTTAGGCAAATCGATTACATTACAACAAGCGAGATCAAGTGGTTTACagTCATGTATTGAACGTATGCTTAATTTAACAGAGCATTTAAGGAGATTAAAAGTAGATAGATATGAATATGTTGCGATGAAAGTTATAGTATTATTACAATCAGacacATCTGAATTAAAAGAGCCTGAAAAAGTGCGAACGAGTCAGGAAAAAGCACTACAAGCATTACAGGCATATACATTATCACATTATCCAGATACACCGGCTAAATTTGGTGAACTTTTATTACGGATACCCGAGCTACAGCGAACGTGCCAGgtGGGAAAAGAAATGCTAATCATTAAATCAAAAGAGGGtgaagaatttaatttactgATGGAATTACTACGAGGTGAACACTAG
- Protein Sequence
- MATTGSTNSNSGSNNCTISSSSSSSCGPPTSRGNVSVTSINCSDDSGIQSQSSQANGSILTNGGATHFYENGGIRISVPKMEESDESDTELTNIENNSNSNVGMRENRNKNIPRPMSWEGELSENEDSNMMIVENGETSNLSATTIQTTSTNTVTTTDEPINLHQLPKEFKPEFLDNNSTSNLTTTSSSATTYLNLNSKKFPEYINLKNETGVHDVISSPLLARSKSNLLPANPSPDSAIHSIYTHSSPSQSPLTSRHTPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQSRHYLYGPNAAQSGLTNSPAHHSLLYRPMLDSEQSTSSKFLQPKEEGVLEGEAIPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTIATRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPGSMLSPSISSESSANLYYSQRLSTNGLLKVETPESSSSTSTFNSNIKLEIPPLLQDIMDVEHLWHYNDAELVRLNQPAPTNQSTNVTSNPLLASAGLSKSDNPDLIANLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRISLGKSITLQQARSSGLQSCIERMLNLTEHLRRLKVDRYEYVAMKVIVLLQSDTSELKEPEKVRTSQEKALQALQAYTLSHYPDTPAKFGELLLRIPELQRTCQVGKEMLIIKSKEGEEFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01458497;
- 90% Identity
- iTF_01458497;
- 80% Identity
- iTF_01454943;