Tcon031006.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tipula confusa
Gene Symbol
Baz2b
Assembly
GCA_963556175.1
Location
OY744477.1:28014317-28065085[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.9e-13 3.8e-09 37.4 0.0 5 75 759 829 756 831 0.90

Sequence Information

Coding Sequence
ATGGGTCTATTAGACGAAGTTTCATATGTTGGTTTTTCAGGTTTTACATACTGGGGCCGGGGAGATCAGGCTGCAGCTGCTGCTGCTGCGGCCGCGGCTGCATCTAATCCATTATTTGCATCACCGTTCGGAGCAGCTGGATTAGGATTATTACCGGGATCTGGTGGCGGAGGTGGTTCATCGAATGATCGTTATTCGTTGGCATCACATCAACAGCATCACAATACAATGGCTGTGGCCGCATCACAGGCCGCCAGTCTCGCTGGGTTGCATCCGGCTAgTTGGTGGTCAATGGCACAATTAGCGGCTCAAGATTATTTCACGCGATTACAAGCATCTGGCCTATCGCCATTTTCCCATCCTGAATTAGCAAGTGCATTTCCGCAATCGTTTGTTAATTCTGGTGGAGGTGGTGGAGGAGGAGGTAGCGGTGGTGGgagtggtggtggtggtggttcgTCACGCAACGGAAACGATAAAGGTAGTAGTAAAAATGCTAAAAAGGAGAAAAAATTACTCGCAGGAAGTGGAAATTCAAATGATAATCGGTCTGGAAGTGGTAGTGGATTGGGGAATAGTAGTGGGGGCAGTAATACTGGATACAagcatCCATCTGCGTCGTCATCATCATATAAATCATCTTTGTATAATCCGGTGAATTTCCATAAAGAATTGCTCGCTATGCAAGCTGCAGCAGCCGCAGCATCAAATAATTCCCATCAATCACAATCTAGTTTATCATCATCGTctaataaaaaatcatcatcatcaaataaTTCGTCGTCAAATTTGTTAGGAAGTTCAAATTCAAAACACCAATCAGGTAGTAATATTAGTAATTTaagtagtagtaataataataatggcgGTGGACAccatcaaaatcaatcatcaaaTCATCATCACAATCGAAGTGAgaataataaagatttaatgctTAATAAACATAATCATGCATCAGCATCATCGCCTGGTATTAATACATCATCATCTTTATCCTCGACATCAGCCTCATCAGCATCATCATCCATGTCCATGAATGCGCTGAGTTCGCTGTCCCAAATAggaaatttgaatttaacatCACAACAGAGTGTTACAGCAGCAATGAATGCACTGGCAGCCGGTTCAACCAAAGCCAAGGATTATATGGCATCTGGAATACTCAAcgCTGCACTAGAAGGTAACGATCCATCCTCAATTCTCGGAGTTCGTCTCCCTCCTGATAccgatataataaaatacaccTCATCAATAGTTGGACCCAAAATTCCGGGGACAACAAATCGTGGCCGAAAGAAGACAATTTCCCTAGACCCAAATCCATTGATGGCCGGCCTGCATGGACTTGGCAGCAGCAGTGGCGGAGGTCGAGGGAGTGGCGGCGGCGGTGGTGGTGATCATCATGGTGGTGGCAACAATAATTCCAGTAATATTAGTTCAATTACTGGTGGTAGTGCGGCAAAACGAGCTAGACTAGATTTAGACTATTCAAATTTACAGAGTGCCCATCAAAATGATCGTATCGAAGTTATAAAACTTCCACCAACGATCACATCAAATGGtgcatttaatttttccaaaacaaataataataccaaTTCGTCTTCGAAAGACGGTTCATCGTCGCACGATTTAAGTGGCGGCGGTGGAAATCCAAACGATTGGTCcggtttaaatttatctaagtcAACTTCATCGTCTCAGAATAATAGTTGTAATTTAAATGATAGTGATGCCGATGCaccattaaatttatcattgaaatccgattcaaaaagtaacaataaaaatatgaacaatagtaataataataataataacaacagtaataataatagtaataataataataataataataatagtaataatagtctTAGCAATATAAATAACAGTAACAATAATTCTGAAATTTCCATAACATCCGGTAGCAATAGTTTACAAAGTCTAAGCTCAATAACCGCAGCACTTGGTACTGGAAGTGGAGGCGATCGTATTTtGCATTATAAAGAGGGTCGACCACGTAATTTAGGTCGTGGtgtttcaaaaccaaaaaagaaTACGGTTGCTTCGCTTCTAGCCCAAAGTCGAGCGGTTGGTTTAAAACCAATGTTGGCCACACAGCAATTACTAAATCAAGGTgcagatttagaaaaaattcgtCAAGCCATATCGGaggcaaatcaaaatttagatgtTTCAACAGATTCGGAAAGTGTGGCGGCCGAATCTGGTATGTCCGAATCGGAAGGCGaagaacaatataatataaacgaTTTGCGGCTACCAATCGATAAAGGTTGGAAACGTGAAACGATAATACGTGGTTTAACAAAAAGTGGGCAAATAAAAGGTGATGTGCATTATATAGCACCGGGTagtcaaacaaaattaaagcacATGAGCCAAGTACAAGGTGTGCTCGATTCAATGTCGAGTAGTTTAAATCGTgatcattttagtttttcacCACGTCCAATTATTGGTACATTTTTACAACCGGCACCGCCCCCATATGCGACCGATAGTGAATTTATTCGCATGACTGATACAGAAGTAGCTAAAAAAttagaagaattaaaaatatttacgcgACATTCGCAGTTAAATGTTGAACAACGGATAGAAATTGCACGACAACAACAAGCATTACGCGATGctaaaaaattggcaaaagaAGAATTGGCTCGAAGTAAAGAAaaggCACGACAAGCTAAAGAGCTAGAAAGAACTGAAAGACTGGAACAAGCTCGTAAAGAGCGAGAACTCAAAAATCAACAAGCCATCGAGGCGCGAAGAAAACGTCAAGAAGAAATTGAAAAGCAAAAACTCGAAGAAACTCAAAGAAAGCAACagGAAAAGGAACTAAAACGACAACAGGCTATTTTGGCTAAGGAACAGGATCTCAACAAACAAAAGGAGTTACTCTACACCGTTGAATTGGAACGCGAAAGGCGACGTCAACATATGAACTTGATAAAGCAGTTAGATTTTCGACGAAAATTTGAAGAGCGTGAAAAGAAAAagcatcaaattattttggataaGCTAATTACACGTgagaaaaaaattgcaacacgCCGTCGTGATGCTGATTTACTGGTCGAATTACGAAAACCGATGGAGGATTCGGAAATTCCAAATCAAAAAGAGCTTCCCGAACTAAAACGTATACCCGGACAACGATTAACCGGTCAAGCACTATCCGATTTATTGATGGCATtcgaatttctaaataattttggtgaaaCACTCGGCTTCGATATGGAATCATTACCAACAATGCAATCGTTACACCAAGCCCTTGTATCGGACGATGCAATCGATGCCGAAGAAGAATTGCTTTCGGTTATGACTCATTTACTAGTGTGCGCCATCGAAGATCCGGGCATACCAAATCCTACACGGCATACAACATTACTTGGACAATCATTGAAACAGGCCGATATTACGAATTCAAATGTTTCcgaaatattacgaatatatttatatgcaacAGCCACTGgtgaagttaaaatattaactgGAATTAATTTTGAACGAGATCGAGAACGACGACTACCCGACCATCATTTGACGGAAGCCGAATTGAATACATCGAATTCGGCTTGCCGAAATACACAATTTTACGAGCAGCTACATGAAAATATGCGTTGGAAATTGTCTGAATTTTTAAAGGATAAACCTTTTGTTGCATTAAATCCTAGTGTTAAAGCTCAAATATTAGCGTTGTTATGTAACGACTTGCTTTTGAATAAAGCGGTTGTCAAACAAATCGAAACAAGTTTGGAGGCGGTGGCCACCCTTAAACGTGAACGATATTTGCTCGAAAATAAAGTGCGAAAATATAAATCATGGCATATGCGAAAAACTCGTATGGAAATTTATGAACGGACCCAACAGCTAGCTATGGAAAAGGCGATGGCGCTTAAATATGAGCACGAAATGAATaacatgaaaaataatgaagaaGCGGCTGCTAAAGCTGCAGAAGCGCTAAATACAGTGACGGCGGCTACAAATTTGGATAACAATAACGAGGCTGAAAAGACAGCGACAACAATAACGATTGAAGAAAATTCGTTCGATAAATCTCAAATCACATTGACCAAATCATCTAGTTCGGAGAATGTGAACGAAATTGGAATAGCTGAGTCTAATCACGATAATGTTAGTATCGATGAGGATAATAATTCGCCTGGGAATACTCCGGGAAAAATAAATGTGATCGATGAGGTTAAGAAAGATACGAGTTTTAATTATATCGAGCCTGCGACGAATATATCAAATAACGGTACTAGTACACCAGATATAAACAGTTTACTTAACAAGACAATCATGTCACACACCGAAGGTGGACTTGAAGATGAATTAAGCGACTTAGAGAGTGAATGTACGATGGTTGAAGAGGATGAAGACACAAAAGTGACCGCCGAAGAAGTACAAAAGAAATTGGAAAAGGTACTTAAAAGTAGTTATCAAACTAATCGTATGTTGGAACATAGTTCGCATCAGCTTCGAGCCACTTACTATGGTCAGGATCGCTATTGGCGACGATATTGGCATCTACCTCGAACTGGAGGAATTTATGTAGAATCGATGGAATCTGCACAGCCCGAAATTTTCAAGTATCACGCAATGCTTGAGGAGCAGGCCGTACAAGATCAAGATTTgcagaatattaaaaatgaacttAAGCTCAGTGATCTTGCTCAAATTACGAAATACGAAGCGAATGACTCCGAAATGGAAAAAATGGAGGAAAAATGTGTTCAAATATCTAAAGAGGATCAAGAAGACGAAATGATGATGGATATAGAGGATTCAATACCGACTGCAGTCCTTGTTCAAAAAACAAATCGATCGTTTAAATCCGAGGACGGGACGATGAGACTCAATGACAGTACtgaaaatattgttgaagttagccaaattaataataatgtacGTCCACCATCTGCACCACTGCAAATTAAACTTGAAACTGCAAAATTAGAACCATCATCGATTGAAGTAACAGATAATATTGTGGTTGAagatgacgacgatgatgatgtgGTTGAGGTGAAACCAACGATGGAGAATGGTGAAATAATTATAGCCGAAGATTCAAAAGATGACGTAATAATACAAGAACCTGACGAGTCGTTCGATAAGAAACCCATTGTGATcaaaacagaaaattgtgaaGAGGAGcagaagttaaaaattaaatcggaatattcgCAACAATTCATTGAGAAATGGTTTTCGTTGATAAATCGTGAAATTCAATTGACATCGACCGAGTACACACCATGTCACAACGCACAAATTGCATATGCTAATATTACGTGCGAGACTATACTTCAGGTGCAGGGAAATCGGTGGGACATTGGAAataatattcaacattttaatattccaCTTGAATACAATTCATGCGATATTGTATTTCCAAACGAGTCGCATCTAACATTGTCCGGATTGGATGATAAAATAATGGAGACGGTGATCAATGGTGGTGAAGGTGTTATAAATAATACTGTTATGGAAACGGAGGAAGATAGTATCAAAGCGGAAGTTAAATCTGAAATTACTGATTGCGAGATAAACGACACAGATTCAATAACGAACGAGTTGAAATCCAATGATTTCAAAACACAACCACGTAACGATGATTTGTATGCGTTCCAACCATCACTTAATATGTCACTCGTTAATTTAAGCACATATATCCAATGCGATAGTCCTAGTCCTCTACAAATGACGGAGGACGAGTATAAATTATTAGAGCAGGTGAAAGCGAATGGGGCACCGCAACGTTtggataaaaattatgtatcagCCGATTTACGTCACGGTTGGTGGAAGATTAACGATATAGAAACATTACATGAACTAGTATCCGCATTACATACGCGTGGAGTACGGGAAAAAGATTTACGCATTAATTTACTTTCGGCCATGGCCGATTCCCTAGACTTGGCGATGCCAAGTAATGTTTTTAATGATGAATTAGGACTCCCACCAAAAGGATATACTGAGTTAGATACGACGATCGCTTGGAATCCTAAAATAGCACATCGTGTGGAACTATCCCTTTTGGAGCAGGTTGAGAGTTTAGAAGATAAAGTCGCGAGTGCTTCGATGCAAATCAAAGGTTGGATAATTCCACAACGCGAAGGTGATTATGATAATGCCGAAGGTTATGTTGGCCTAATCAGCGTGATAAAAGATCGTATACTTGGTTTAGAGTCGGCCATCGAGCGCCGTTATTTAAAACCTCCACTAGGAATTAATACTGCCGAGGCAAAACTTGCCGCCATAGCACAAGGACAGGATGCACAAAAGAAATCGACTACCAGCCATCGTAACGACGACCTAGACAGTAATGTTGGTAGTCCCGGATCAGCCAGTCTTGATGAATTTGATAATATAACCAAAGGCTTGGCGTCGTGGCGTGAAGCTGTGTCTCGATCAAATACAAGTTCTCAGTTGGCGATGGCATTGTACGTACTAGAATCATGTGTAGCCTGGGACAAGAGTATTATGAAAGCGaATTGCCAGTTTTGCCACTCGGGCGAATGTGAGGACAAATTGCTTTTGTGTGATGGATGTGACAAAGGTTACCATACGTACTGTTTTAAGCCAAAAATGGAGAAAATTCCAGAAGGTGATTGGTactgttttgaatgtttgaataAAGCGACAAGTGAACGAAAATGTATTGTTTGCGGTGGACATCGTATAGCACCTGTCGGCAAAATGATTTACTGTGATTTGTGTCCGCGTGCTTATCATCATGACTGTTACATTCCACCGTTGTTGAAAGTACCGCGAGGTAAATGGTACTGTCATGATTGCGTTTCTCGAGCACCGCCACCCAAAAAAAGGCCACGCAAagaaaaaaccgaaaaaatgaAGAGTCATAATTCGTCGCAATCATTAAATTCATCGCACGACGAAATGCCACCAAGtccTGCTCATTCCGTTGCATCAACTTCGTGTGACGATCATCACATACCCGATGCTAAATTTGGTTCGAATTCTATTCCAGTACTACCATTGTCGATACCATCACCATTACCGATCAACAATGAAATATGTGAAACTAGTTTAGACGATATCGGTATAAACAATAGTAGTTGTAGCGCAGGAGCACCTCCAATACCCACAACGGCTGTGACATCTCCaccgccaccaccaccaccggTGCCAATGATTACTCATTCTTCTCCGATCTCTCCACCAATACCAAACTCAACCAGTAACACTAGTGGTAATAGTATTATCAACGTAACACCATCGTCATCTCAATTGGACGCATCTTTAGCAAAAACGATTAGTGAGAATAAAGAAAAGCTAAAGCAggaaaagaaagaaaaacattCAGCCAAAAAACTTATGAAAGAATTGGCTGtgtgcaaaattattttagaggaAATGGAGttacaCGAAGATGCATGGCCATTTTTATTGCCGGTGAATACAAAACAATTCCCAACGTataagaaaatcattaaaattccaATGGATCTATCAACGATTAAAAAAAGACTACAAGAAATAATATACAAATCCCGCGATGATTTTATCGTTGATGTTCGACAAATATTCGATAATTGCGAAGTATTCAACGAAGATGATTCACCAGTTGGCAAAGCTGGTCATGGTAtgcgaaaattttttgaaatgagaTGGAATGAATTGACCGACAAACAGTCATGA
Protein Sequence
MGLLDEVSYVGFSGFTYWGRGDQAAAAAAAAAAASNPLFASPFGAAGLGLLPGSGGGGGSSNDRYSLASHQQHHNTMAVAASQAASLAGLHPASWWSMAQLAAQDYFTRLQASGLSPFSHPELASAFPQSFVNSGGGGGGGGSGGGSGGGGGSSRNGNDKGSSKNAKKEKKLLAGSGNSNDNRSGSGSGLGNSSGGSNTGYKHPSASSSSYKSSLYNPVNFHKELLAMQAAAAAASNNSHQSQSSLSSSSNKKSSSSNNSSSNLLGSSNSKHQSGSNISNLSSSNNNNGGGHHQNQSSNHHHNRSENNKDLMLNKHNHASASSPGINTSSSLSSTSASSASSSMSMNALSSLSQIGNLNLTSQQSVTAAMNALAAGSTKAKDYMASGILNAALEGNDPSSILGVRLPPDTDIIKYTSSIVGPKIPGTTNRGRKKTISLDPNPLMAGLHGLGSSSGGGRGSGGGGGGDHHGGGNNNSSNISSITGGSAAKRARLDLDYSNLQSAHQNDRIEVIKLPPTITSNGAFNFSKTNNNTNSSSKDGSSSHDLSGGGGNPNDWSGLNLSKSTSSSQNNSCNLNDSDADAPLNLSLKSDSKSNNKNMNNSNNNNNNNSNNNSNNNNNNNNSNNSLSNINNSNNNSEISITSGSNSLQSLSSITAALGTGSGGDRILHYKEGRPRNLGRGVSKPKKNTVASLLAQSRAVGLKPMLATQQLLNQGADLEKIRQAISEANQNLDVSTDSESVAAESGMSESEGEEQYNINDLRLPIDKGWKRETIIRGLTKSGQIKGDVHYIAPGSQTKLKHMSQVQGVLDSMSSSLNRDHFSFSPRPIIGTFLQPAPPPYATDSEFIRMTDTEVAKKLEELKIFTRHSQLNVEQRIEIARQQQALRDAKKLAKEELARSKEKARQAKELERTERLEQARKERELKNQQAIEARRKRQEEIEKQKLEETQRKQQEKELKRQQAILAKEQDLNKQKELLYTVELERERRRQHMNLIKQLDFRRKFEEREKKKHQIILDKLITREKKIATRRRDADLLVELRKPMEDSEIPNQKELPELKRIPGQRLTGQALSDLLMAFEFLNNFGETLGFDMESLPTMQSLHQALVSDDAIDAEEELLSVMTHLLVCAIEDPGIPNPTRHTTLLGQSLKQADITNSNVSEILRIYLYATATGEVKILTGINFERDRERRLPDHHLTEAELNTSNSACRNTQFYEQLHENMRWKLSEFLKDKPFVALNPSVKAQILALLCNDLLLNKAVVKQIETSLEAVATLKRERYLLENKVRKYKSWHMRKTRMEIYERTQQLAMEKAMALKYEHEMNNMKNNEEAAAKAAEALNTVTAATNLDNNNEAEKTATTITIEENSFDKSQITLTKSSSSENVNEIGIAESNHDNVSIDEDNNSPGNTPGKINVIDEVKKDTSFNYIEPATNISNNGTSTPDINSLLNKTIMSHTEGGLEDELSDLESECTMVEEDEDTKVTAEEVQKKLEKVLKSSYQTNRMLEHSSHQLRATYYGQDRYWRRYWHLPRTGGIYVESMESAQPEIFKYHAMLEEQAVQDQDLQNIKNELKLSDLAQITKYEANDSEMEKMEEKCVQISKEDQEDEMMMDIEDSIPTAVLVQKTNRSFKSEDGTMRLNDSTENIVEVSQINNNVRPPSAPLQIKLETAKLEPSSIEVTDNIVVEDDDDDDVVEVKPTMENGEIIIAEDSKDDVIIQEPDESFDKKPIVIKTENCEEEQKLKIKSEYSQQFIEKWFSLINREIQLTSTEYTPCHNAQIAYANITCETILQVQGNRWDIGNNIQHFNIPLEYNSCDIVFPNESHLTLSGLDDKIMETVINGGEGVINNTVMETEEDSIKAEVKSEITDCEINDTDSITNELKSNDFKTQPRNDDLYAFQPSLNMSLVNLSTYIQCDSPSPLQMTEDEYKLLEQVKANGAPQRLDKNYVSADLRHGWWKINDIETLHELVSALHTRGVREKDLRINLLSAMADSLDLAMPSNVFNDELGLPPKGYTELDTTIAWNPKIAHRVELSLLEQVESLEDKVASASMQIKGWIIPQREGDYDNAEGYVGLISVIKDRILGLESAIERRYLKPPLGINTAEAKLAAIAQGQDAQKKSTTSHRNDDLDSNVGSPGSASLDEFDNITKGLASWREAVSRSNTSSQLAMALYVLESCVAWDKSIMKANCQFCHSGECEDKLLLCDGCDKGYHTYCFKPKMEKIPEGDWYCFECLNKATSERKCIVCGGHRIAPVGKMIYCDLCPRAYHHDCYIPPLLKVPRGKWYCHDCVSRAPPPKKRPRKEKTEKMKSHNSSQSLNSSHDEMPPSPAHSVASTSCDDHHIPDAKFGSNSIPVLPLSIPSPLPINNEICETSLDDIGINNSSCSAGAPPIPTTAVTSPPPPPPPVPMITHSSPISPPIPNSTSNTSGNSIINVTPSSSQLDASLAKTISENKEKLKQEKKEKHSAKKLMKELAVCKIILEEMELHEDAWPFLLPVNTKQFPTYKKIIKIPMDLSTIKKRLQEIIYKSRDDFIVDVRQIFDNCEVFNEDDSPVGKAGHGMRKFFEMRWNELTDKQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01457347;
90% Identity
-
80% Identity
-