Tfem004227.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tiphia femorata
Gene Symbol
hmgxb4
Assembly
GCA_944319705.1
Location
CALUEQ010000085.1:3624-6124[+]

Transcription Factor Domain

TF Family
HMG
Domain
HMG_box domain
PFAM
PF00505
TF Group
Other Alpha-Helix Group
Description
High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 9.1e-14 6.8e-11 42.6 0.5 5 59 227 281 224 285 0.94
2 2 1.7 1.3e+03 0.0 0.0 39 54 295 310 292 315 0.87

Sequence Information

Coding Sequence
ATGCAAACGAACATTCGTAAGCCCGCGAAATCTGAGAAGACGCTGCGCCGCAAGAAGCTTGGCGAGGAACGAAGCGACGCAATGGATATGTTCGTCTCACCGAAGCGTCAAAAAAGTGACGATCTAGAGGTCACGGGTATCTCCCGCAGTGGCCGTGTAAGAAAGAAATCATCAAAATTAGTTGATTTTGAATCTCCCGATGACTTTGCGGACAATAAATACAAACGACAGAAAGCGCAGCAATTACAAGCTCAGCAATTGTTAGACCGATATGAAGTGTCGCAACAGCATGTATCTCCAAATCAACCACTTCAACAAGGAAGTGCCGGGAGACAAAGAAAGAACTCAGGTTCTCATTTGGCACAGCAGAGAGTTAAAGCAGAACCTTTATCTGATAATGAGGCACAGTCATCGGGATCGGAATCCGATGATCCAAGTGGGATAAACGAGGAGGATAGATACAGTATGGAATCTGGAAGCGACGATGAAGTAGACCCGCTTATGATTGACGATAGAGAAACTGGATTTAGAAAACTCGAACCGCCGGGACAAGAAAGCACGCCATCGCAAGCGAAGAGCTTGTATATGCTCGAAAAGTGTAAAAAGAAATTAATTATCAAAGATGGTAAAATTATAGGGAGAATGAAGGCGCAACGGAAAGATAAAGGGAAAACAAGGTTTACCGCATACATGCTGTGGGCGAAGGAAATCAGGCAAGAATTATTAGAACAATGTCCTTATATGGATTTCGCAGCAATTTCTAAACGGTTAGGAGAACTTTGGGCTACTGTTCCAAATCTGGAAAAGTATAATTGGCGCAGACGTGCGAAACGTTTAGCAGCAAAACCTCATTCTTTACCAGCGAGTAAAGATGAGCCTGTTTGGAAAATGCCGCCGCCAGCCTCGCGAAAAAAATTCATTAACAAAATTGGTAATGGAAAAGAGATCAAGCCTGCTTCTTCAAAAAAGACTATTCAATTAGGTGTACCCTCCGTTGTAGGAAATGTTCCAGTTTCACCACCATCGCATAGGCCTGGAAAGGATTTGGTTAATGAGCCTGTTATTGGTACAGGCATGTACAAAGTTGTTGGAACACAACCTATTGATGTTGCTGCCCACTTGAAATTACTTGGAGAGAGCTTAACAATTATTGGTGAAAGATTGAAGGAACACGATGGCCAAATAGCAGTTTCAGGCAGTCTTTCGGTTTTGTTGGATTCGCTTCTTTGTGCGCTGGGTCCCTTGATTTGCCTAACACAACAAGTGTCTGAAACAAATGGAGCTAAGCATGAAACCTTATCACAAATGCTTGataatattgcatatctcatgcctggtctataa
Protein Sequence
MQTNIRKPAKSEKTLRRKKLGEERSDAMDMFVSPKRQKSDDLEVTGISRSGRVRKKSSKLVDFESPDDFADNKYKRQKAQQLQAQQLLDRYEVSQQHVSPNQPLQQGSAGRQRKNSGSHLAQQRVKAEPLSDNEAQSSGSESDDPSGINEEDRYSMESGSDDEVDPLMIDDRETGFRKLEPPGQESTPSQAKSLYMLEKCKKKLIIKDGKIIGRMKAQRKDKGKTRFTAYMLWAKEIRQELLEQCPYMDFAAISKRLGELWATVPNLEKYNWRRRAKRLAAKPHSLPASKDEPVWKMPPPASRKKFINKIGNGKEIKPASSKKTIQLGVPSVVGNVPVSPPSHRPGKDLVNEPVIGTGMYKVVGTQPIDVAAHLKLLGESLTIIGERLKEHDGQIAVSGSLSVLLDSLLCALGPLICLTQQVSETNGAKHETLSQMLDNIAYLMPGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00393579; iTF_00729281; iTF_01245200; iTF_00730038; iTF_00730717; iTF_00279940; iTF_00280589; iTF_01233634; iTF_01232385; iTF_01234325; iTF_01235006; iTF_01232384; iTF_01512813; iTF_01512165; iTF_01513453; iTF_01514806; iTF_01514136; iTF_01232979; iTF_01089977; iTF_00360194; iTF_00117990; iTF_00306246; iTF_00760966; iTF_00360886; iTF_01169150; iTF_00769603; iTF_01409090; iTF_01228999; iTF_01228353; iTF_01255529; iTF_01477546; iTF_01087179; iTF_01520207; iTF_01077444; iTF_00452560; iTF_00867377; iTF_00868776; iTF_00125906; iTF_00126693; iTF_01406473; iTF_00127435; iTF_01405676; iTF_00128181; iTF_00128954; iTF_01407258; iTF_01408186; iTF_00129724; iTF_00016663; iTF_01254775; iTF_01355288; iTF_00015353; iTF_00264250; iTF_01354589; iTF_00898724; iTF_01099166; iTF_00625477; iTF_00754629; iTF_01523340; iTF_00756621; iTF_00109806; iTF_00733938; iTF_00983580; iTF_01015794; iTF_01537938; iTF_01498203; iTF_00966012; iTF_00219777; iTF_00231297; iTF_00225894; iTF_00228646; iTF_00227943; iTF_00232584; iTF_00215689; iTF_00222505; iTF_00223853; iTF_00230669; iTF_00220558; iTF_00229330; iTF_00224531; iTF_00219092; iTF_00214998; iTF_00230007; iTF_00227256; iTF_00217050; iTF_00218395; iTF_00217728; iTF_00223168; iTF_00225216; iTF_00303009; iTF_01418977; iTF_00221890; iTF_01123042; iTF_00963169; iTF_01539585; iTF_00684770; iTF_01424357; iTF_00964457; iTF_01122413; iTF_00961806; iTF_00684147; iTF_00963829; iTF_00962490; iTF_00088803; iTF_00087142; iTF_00087978; iTF_00085355; iTF_00084531; iTF_00086259; iTF_00216371; iTF_00982947; iTF_01419619; iTF_01067591; iTF_01066920; iTF_01068954; iTF_01070344; iTF_01065549; iTF_01069647; iTF_01068277; iTF_01066235; iTF_00763210; iTF_00762531; iTF_00864620; iTF_00860368; iTF_00865298; iTF_00863251; iTF_00861119; iTF_00873773; iTF_00142446; iTF_00862542; iTF_00141807; iTF_00140563; iTF_00141210; iTF_01420912; iTF_01418329; iTF_01420256; iTF_01417682; iTF_00183925; iTF_00183267; iTF_00024600; iTF_00231962; iTF_00214372; iTF_00866684; iTF_00865989; iTF_00982269; iTF_00863934; iTF_01071006; iTF_00676000; iTF_00861856; iTF_01120190; iTF_00773791;
90% Identity
iTF_00360886;
80% Identity
-